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The map label for this gene is hisJ [H]

Identifier: 116871956

GI number: 116871956

Start: 569625

End: 570452

Strand: Direct

Name: hisJ [H]

Synonym: lwe0536

Alternate gene names: 116871956

Gene position: 569625-570452 (Clockwise)

Preceding gene: 116871945

Following gene: 116871958

Centisome position: 20.24

GC content: 37.32

Gene sequence:

>828_bases
ATGAAAAGAGACGGGCACACGCATACCGAATTTTGTCCACATGGTACGCATGATGATGTGGAGGAAATGGTTTTAAAAGC
GATTGAACTTGATTTTGATGAGTATTCTATTGTTGAACATGCACCGCTTTCGAGTGAGTTTATGAAAAATACTGCTGGTG
ATAGCAAAGCCGTAACGACCGCAAGTATGGCAATGAGTGATCTGCCTTATTATTTTAAAAAAATGAACCATATAAAGAAA
AAATATGCGAGCGATTTATTCATACATATTGGATTGGAAGTAGATTATTTGATTGGTTATGAGGATTTTACGCGAGATTT
TTTAAATGAGTATGGACCACAAACTGATGATGGCGTGTTGTCCTTACATTTTTTAGAAGGGCAAGGTGGATTTCGTTCGA
TTGATTTTTCGGCGGAAGATTATAATGAAGGAATTGTGCAATTTTATGGTGGATTTGAACAAGCGCAACTTGCTTATTTG
GAAGGTGTGAAACAGTCGATTGAAGCGGATTTAGGTCTATTTAAACCGCGGAGGATAGGACATATTTCATTGTGTCAGAA
GTTTCAACAGTTTTTTGGAGTAAGTACACCTGATTTTTCAGAAGAAGTAATGGAAGAATTTCAAGCGATTCTTGCTCTAG
TGAAAAAGCGCGATTATGAGCTTGATTTTAATACGGCGGGCCTATTTAAGCCACTTTGCGGAGAAACTTACCCACCTAAA
GAAATCGTGACTTTAGCTAGTGAGTTAAAGATTCCATTTGTATATGGATCTGATTCGCATGGTGTTCAAGATATTGGTCG
TGGTTATAACACTTATTGCCAAAAATGA

Upstream 100 bases:

>100_bases
TTAGCACGTTAAAGCATTTTTGTAAATAATGAATAGAAAAATAATTCCATATGGTATAATTAATCTAGCATTTAGCGCAT
TTAAGGAAAGAGGGTTGAAT

Downstream 100 bases:

>100_bases
TCTTTCATTTTGACATGTCCATTTTCTTTAAATGTAATACCTTCTAATAGAAGCAGTTCGCGTTGTTCTTCCCAACCCGG
GACGAGGCGACCAGCTGCAT

Product: histidinol-phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MKRDGHTHTEFCPHGTHDDVEEMVLKAIELDFDEYSIVEHAPLSSEFMKNTAGDSKAVTTASMAMSDLPYYFKKMNHIKK
KYASDLFIHIGLEVDYLIGYEDFTRDFLNEYGPQTDDGVLSLHFLEGQGGFRSIDFSAEDYNEGIVQFYGGFEQAQLAYL
EGVKQSIEADLGLFKPRRIGHISLCQKFQQFFGVSTPDFSEEVMEEFQAILALVKKRDYELDFNTAGLFKPLCGETYPPK
EIVTLASELKIPFVYGSDSHGVQDIGRGYNTYCQK

Sequences:

>Translated_275_residues
MKRDGHTHTEFCPHGTHDDVEEMVLKAIELDFDEYSIVEHAPLSSEFMKNTAGDSKAVTTASMAMSDLPYYFKKMNHIKK
KYASDLFIHIGLEVDYLIGYEDFTRDFLNEYGPQTDDGVLSLHFLEGQGGFRSIDFSAEDYNEGIVQFYGGFEQAQLAYL
EGVKQSIEADLGLFKPRRIGHISLCQKFQQFFGVSTPDFSEEVMEEFQAILALVKKRDYELDFNTAGLFKPLCGETYPPK
EIVTLASELKIPFVYGSDSHGVQDIGRGYNTYCQK
>Mature_275_residues
MKRDGHTHTEFCPHGTHDDVEEMVLKAIELDFDEYSIVEHAPLSSEFMKNTAGDSKAVTTASMAMSDLPYYFKKMNHIKK
KYASDLFIHIGLEVDYLIGYEDFTRDFLNEYGPQTDDGVLSLHFLEGQGGFRSIDFSAEDYNEGIVQFYGGFEQAQLAYL
EGVKQSIEADLGLFKPRRIGHISLCQKFQQFFGVSTPDFSEEVMEEFQAILALVKKRDYELDFNTAGLFKPLCGETYPPK
EIVTLASELKIPFVYGSDSHGVQDIGRGYNTYCQK

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 31229; Mature: 31229

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRDGHTHTEFCPHGTHDDVEEMVLKAIELDFDEYSIVEHAPLSSEFMKNTAGDSKAVTT
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHCCCCCHHHHH
ASMAMSDLPYYFKKMNHIKKKYASDLFIHIGLEVDYLIGYEDFTRDFLNEYGPQTDDGVL
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEEECHHHHHHHHHHHHCCCCCCCEE
SLHFLEGQGGFRSIDFSAEDYNEGIVQFYGGFEQAQLAYLEGVKQSIEADLGLFKPRRIG
EEEEEECCCCCEEECCCCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
HISLCQKFQQFFGVSTPDFSEEVMEEFQAILALVKKRDYELDFNTAGLFKPLCGETYPPK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCHH
EIVTLASELKIPFVYGSDSHGVQDIGRGYNTYCQK
HHHHHHHHCCCEEEECCCCCCHHHHHCCHHHHCCC
>Mature Secondary Structure
MKRDGHTHTEFCPHGTHDDVEEMVLKAIELDFDEYSIVEHAPLSSEFMKNTAGDSKAVTT
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHCCCCCHHHHH
ASMAMSDLPYYFKKMNHIKKKYASDLFIHIGLEVDYLIGYEDFTRDFLNEYGPQTDDGVL
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEEECHHHHHHHHHHHHCCCCCCCEE
SLHFLEGQGGFRSIDFSAEDYNEGIVQFYGGFEQAQLAYLEGVKQSIEADLGLFKPRRIG
EEEEEECCCCCEEECCCCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
HISLCQKFQQFFGVSTPDFSEEVMEEFQAILALVKKRDYELDFNTAGLFKPLCGETYPPK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCHH
EIVTLASELKIPFVYGSDSHGVQDIGRGYNTYCQK
HHHHHHHHCCCEEEECCCCCCHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]