| Definition | Listeria welshimeri serovar 6b str. SLCC5334, complete genome. |
|---|---|
| Accession | NC_008555 |
| Length | 2,814,130 |
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The map label for this gene is thiD [H]
Identifier: 116871708
GI number: 116871708
Start: 313230
End: 314033
Strand: Direct
Name: thiD [H]
Synonym: lwe0288
Alternate gene names: 116871708
Gene position: 313230-314033 (Clockwise)
Preceding gene: 116871707
Following gene: 116871709
Centisome position: 11.13
GC content: 42.41
Gene sequence:
>804_bases ATGATTTTCAAACAAGTGTTAACGATAGCTGGTTCAGATTCAGGTGGCGGCGCGGGAATCCAAGCAGATATTAAGACATT TCAAGAGCGCAGAACCTTTGGAATGTCTGTTATCACCGCAATTACAGCACAAAATACATTAGGTGTAAAAGCAGTGCATA AAATCCCAATAGATATCATTTGCAAACAGTGCACCGCGATTGCTGAGGATTTCCAAGTGAGTGCTGTGAAAACTGGTATG CTGGCAGATGCAGAAATTATTCGGGAAGTGGCGCGGAATATACGTTTGTACGATTTTCCCAATTTGGTTATTGATCCGGT GATGATTGCGAAGGGCGGCACAGCTTTGCTTGAAAACGAGGCTATACGAGTTTTGAAAGAGGAGCTTTTGCCGCTTGGTA CGATTATTACGCCAAATATTCCAGAAGCCGAAGAAATTCTTGGAGAAAAAATCACAACCAAGGCGGAAATTGAACAGGCT GCTAAGAAAATTTGTGATTTGGGAATAAAAGCGGTAGTTATTAAAGGAGGACATAGCGAAATGAGTGAGGCGGCTGATTT TTACTATGATGGCAAAACGACGAAATGGCTTACAAGTGAGCGTTTTGATACGCTACATACGCACGGAACTGGTTGTACTT TTTCGGCATGTATTGCGGCTGAGCTTGCGAAAGGGAATTCCCTTTTAAATAGCGTGATAGTTGCGAAAGAGTTTATCACG AGTGCAATTAAATATCCGCTTGGAATTGGTCACGGTCATGGTCCAACCAACCATTTTGCTTATAGAATGGAGGAAGGTAA GTGA
Upstream 100 bases:
>100_bases TCCCAGGCTCTTTTCGACCATTATTTTTGGATGCGCTGGCTAGTTGGTCGGTCGAAAAAACGCGTGCTAAAGCCAAAATC CTAGAAAGTGGTGAACACAA
Downstream 100 bases:
>100_bases AAGAAGAATTAGCTGTATATTTTATCGCTGGAACGCAAGACATTGTGCGCGGAACGTTGCCAAGTGTGTTAGAAGAAGCA CTGAAAGGCGGAATCACTTG
Product: phosphomethylpyrimidine kinase
Products: NA
Alternate protein names: Hydroxymethylpyrimidine kinase; HMP kinase; Hydroxymethylpyrimidine phosphate kinase; HMP-P kinase; HMP-phosphate kinase; HMPP kinase [H]
Number of amino acids: Translated: 267; Mature: 267
Protein sequence:
>267_residues MIFKQVLTIAGSDSGGGAGIQADIKTFQERRTFGMSVITAITAQNTLGVKAVHKIPIDIICKQCTAIAEDFQVSAVKTGM LADAEIIREVARNIRLYDFPNLVIDPVMIAKGGTALLENEAIRVLKEELLPLGTIITPNIPEAEEILGEKITTKAEIEQA AKKICDLGIKAVVIKGGHSEMSEAADFYYDGKTTKWLTSERFDTLHTHGTGCTFSACIAAELAKGNSLLNSVIVAKEFIT SAIKYPLGIGHGHGPTNHFAYRMEEGK
Sequences:
>Translated_267_residues MIFKQVLTIAGSDSGGGAGIQADIKTFQERRTFGMSVITAITAQNTLGVKAVHKIPIDIICKQCTAIAEDFQVSAVKTGM LADAEIIREVARNIRLYDFPNLVIDPVMIAKGGTALLENEAIRVLKEELLPLGTIITPNIPEAEEILGEKITTKAEIEQA AKKICDLGIKAVVIKGGHSEMSEAADFYYDGKTTKWLTSERFDTLHTHGTGCTFSACIAAELAKGNSLLNSVIVAKEFIT SAIKYPLGIGHGHGPTNHFAYRMEEGK >Mature_267_residues MIFKQVLTIAGSDSGGGAGIQADIKTFQERRTFGMSVITAITAQNTLGVKAVHKIPIDIICKQCTAIAEDFQVSAVKTGM LADAEIIREVARNIRLYDFPNLVIDPVMIAKGGTALLENEAIRVLKEELLPLGTIITPNIPEAEEILGEKITTKAEIEQA AKKICDLGIKAVVIKGGHSEMSEAADFYYDGKTTKWLTSERFDTLHTHGTGCTFSACIAAELAKGNSLLNSVIVAKEFIT SAIKYPLGIGHGHGPTNHFAYRMEEGK
Specific function: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P [H]
COG id: COG0351
COG function: function code H; Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the thiD family [H]
Homologues:
Organism=Escherichia coli, GI1788420, Length=256, Percent_Identity=40.234375, Blast_Score=198, Evalue=2e-52, Organism=Saccharomyces cerevisiae, GI6325378, Length=269, Percent_Identity=33.457249070632, Blast_Score=137, Evalue=2e-33, Organism=Saccharomyces cerevisiae, GI6324517, Length=268, Percent_Identity=33.5820895522388, Blast_Score=125, Evalue=9e-30, Organism=Saccharomyces cerevisiae, GI6324997, Length=268, Percent_Identity=33.5820895522388, Blast_Score=124, Evalue=1e-29,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013749 - InterPro: IPR004399 [H]
Pfam domain/function: PF08543 Phos_pyr_kin [H]
EC number: =2.7.1.49; =2.7.4.7 [H]
Molecular weight: Translated: 28791; Mature: 28791
Theoretical pI: Translated: 6.40; Mature: 6.40
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIFKQVLTIAGSDSGGGAGIQADIKTFQERRTFGMSVITAITAQNTLGVKAVHKIPIDII CCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHH CKQCTAIAEDFQVSAVKTGMLADAEIIREVARNIRLYDFPNLVIDPVMIAKGGTALLENE HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEECCCHHCCCEEEECCCCHHHHHH AIRVLKEELLPLGTIITPNIPEAEEILGEKITTKAEIEQAAKKICDLGIKAVVIKGGHSE HHHHHHHHHCCCCCEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCHH MSEAADFYYDGKTTKWLTSERFDTLHTHGTGCTFSACIAAELAKGNSLLNSVIVAKEFIT HHHHHHEEECCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH SAIKYPLGIGHGHGPTNHFAYRMEEGK HHHHCCCCCCCCCCCCCCEEEEECCCC >Mature Secondary Structure MIFKQVLTIAGSDSGGGAGIQADIKTFQERRTFGMSVITAITAQNTLGVKAVHKIPIDII CCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHH CKQCTAIAEDFQVSAVKTGMLADAEIIREVARNIRLYDFPNLVIDPVMIAKGGTALLENE HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEECCCHHCCCEEEECCCCHHHHHH AIRVLKEELLPLGTIITPNIPEAEEILGEKITTKAEIEQAAKKICDLGIKAVVIKGGHSE HHHHHHHHHCCCCCEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCHH MSEAADFYYDGKTTKWLTSERFDTLHTHGTGCTFSACIAAELAKGNSLLNSVIVAKEFIT HHHHHHEEECCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH SAIKYPLGIGHGHGPTNHFAYRMEEGK HHHHCCCCCCCCCCCCCCEEEEECCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7542800 [H]