Click here to switch to the map view.

The map label for this gene is yycG [H]

Identifier: 116871682

GI number: 116871682

Start: 283259

End: 285091

Strand: Direct

Name: yycG [H]

Synonym: lwe0262

Alternate gene names: 116871682

Gene position: 283259-285091 (Clockwise)

Preceding gene: 116871681

Following gene: 116871683

Centisome position: 10.07

GC content: 37.7

Gene sequence:

>1833_bases
ATGCATAAAATGAGATTTTTTCAGTCTGTACAATTTAAGTTAGTTATTATGTATTTGCTATTAATTATTGTAGCGATGCA
AGTAATCGGTGCGTATTTTGTGCGTGAGCTTGAAGGACAATTAGAGAAGAATTTCCAGAATTCTATTACAAACAGCATAA
CGCTGCTAGATTATAATGCCAGAGAAGAAATCATTAAAAATAGCGATAACTCAGTGAAATTACAAAATGATATCCGAGAA
CTTTTAGTCGATTTTTCGCGTGCAAGTAGTAATTTAATAGAAGTAAGAATAGTAGATGAAAAAGGTAAAATTCTTGGCAC
ATCTAATTTAAACAATCAAGGTATCGTTGGACAAAAGAGCAACGATCCGCTTGTTAAACGAACGTTATCTCTTGGAACAA
CTTCCGAAGATAAAATTTATAAAGACGAATCAAATAAAAATAACCGTGTTTGGGTTAACGTATCCTCTATCAAAAATAAA
GGCGAAGTGATAGGGGCTATTTATCTTGTCGCTGATATTGAAAGTGTTTATAAACAAGTGGACGATATCACGAATATTTT
CATCACAGGAACTTTGATTGCGATGGTTATTACTGCAATTCTAGGTATTTTACTATCAAGAACAATTACGAAACCAATTG
TCGAAATGAAACGCCAAGCTTATGCAATGGCTCGCGGGAATTACAGCCGCAAAGTTAAAGTTTACGGTGTAGATGAAATT
GGGGAACTTGCTGATTCCTTTAATACGCTAACGAAACGTGTTCAGGAAGCACAAGCCATGACAGAAGGGGAAAGGCGCAA
ACTTTCCTCCGTATTAGCCTATATGACCGACGGCGTAATCGCTACAGACCGGCGTGGAAAAGTTATTCTAATTAATACTC
CAGCAGAAAAAATGCTACGAGTTAAACACGAAAGCGCAAATGGACGTTCTATCATTGATGTGTTGGATATTGGAGATAGC
TACCAATTTGAAGATTTAATGGAAGTTGACGGGTCGCTAACGATGGACCGCAGCACGCTTGATAAGCCTTATATTCTTCG
TGCCAATTTTTCCGTTATTCAACGTGAAACTGGCTTCAATAATGGTGTTATCGCAGTTTTACATGATATTACAGATCAAG
AAAAAGTGGATCAAGAACGCCGCGATTTTGTATCCAACGTATCGCATGAATTAAGAACCCCACTTACAAGTATGCACAGC
TATTTGGAAGCACTAAGCGACGGAGCTTGGGAAGATAAAGAAATTGCACCACGCTTCCTTGAAGTAACACAAAATGAAAC
AGAACGAATGATTCGCCTTGTCAATGATTTGCTTAAACTCTCTAGAATGGACGGCGGTAGAGAACACTTAGAAAAAAGTT
TCGTGAATTTCACGGACTTCTTTAACCATATTATCGATCGGTTTGAAATGATGAAAAAAGAAACGATTATGTTCAAACGG
CATATTCCAAAAGAGCCAGTTATTATTGAAATTGATGAAGATAAAGTGATGCAAGTGCTAGATAATATCATATCTAATGC
GAATAAATATTCACCAGATGGGGGAAGAATTTCGTTTTATTTGAAGAAGTTTGAAGATGAAATTGAAATTAGTATCGCTG
ATGAAGGTTTAGGTGTACCAGAAGAAGATTTAGCAAATGTATTCGACCGATTCTTCCGCGTAGATAAAGCTCGTTCGCGG
GAAATGGGAGGAACAGGGTTAGGACTGGCTATAGCTCGAGAAGTCATCGAAGCGCATGGCGGTCGAATTTGGGCAGAACG
TAACAAGTCCAAAGGTACAGTTATTAAATTCACCCTGCCATATAGTGACTTACCGGAGGATGATTGGGAATGA

Upstream 100 bases:

>100_bases
TAAATAAATGGGCCCAAATAATAAGAAAAACCATATCTCTTACTGGAACATATGGTATACTAATCTCAATATATGACCCC
GAATAGGAGTAGAAAGACTT

Downstream 100 bases:

>100_bases
TGAAAAAAACAGGATTTCGTTCATTTTTATTAACAATTTTAGTTATACTCAGCATCGTCTTAAGCTACTTTATTTGGAAA
GGACAACCCGATTACGAAGC

Product: two-component sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 610; Mature: 610

Protein sequence:

>610_residues
MHKMRFFQSVQFKLVIMYLLLIIVAMQVIGAYFVRELEGQLEKNFQNSITNSITLLDYNAREEIIKNSDNSVKLQNDIRE
LLVDFSRASSNLIEVRIVDEKGKILGTSNLNNQGIVGQKSNDPLVKRTLSLGTTSEDKIYKDESNKNNRVWVNVSSIKNK
GEVIGAIYLVADIESVYKQVDDITNIFITGTLIAMVITAILGILLSRTITKPIVEMKRQAYAMARGNYSRKVKVYGVDEI
GELADSFNTLTKRVQEAQAMTEGERRKLSSVLAYMTDGVIATDRRGKVILINTPAEKMLRVKHESANGRSIIDVLDIGDS
YQFEDLMEVDGSLTMDRSTLDKPYILRANFSVIQRETGFNNGVIAVLHDITDQEKVDQERRDFVSNVSHELRTPLTSMHS
YLEALSDGAWEDKEIAPRFLEVTQNETERMIRLVNDLLKLSRMDGGREHLEKSFVNFTDFFNHIIDRFEMMKKETIMFKR
HIPKEPVIIEIDEDKVMQVLDNIISNANKYSPDGGRISFYLKKFEDEIEISIADEGLGVPEEDLANVFDRFFRVDKARSR
EMGGTGLGLAIAREVIEAHGGRIWAERNKSKGTVIKFTLPYSDLPEDDWE

Sequences:

>Translated_610_residues
MHKMRFFQSVQFKLVIMYLLLIIVAMQVIGAYFVRELEGQLEKNFQNSITNSITLLDYNAREEIIKNSDNSVKLQNDIRE
LLVDFSRASSNLIEVRIVDEKGKILGTSNLNNQGIVGQKSNDPLVKRTLSLGTTSEDKIYKDESNKNNRVWVNVSSIKNK
GEVIGAIYLVADIESVYKQVDDITNIFITGTLIAMVITAILGILLSRTITKPIVEMKRQAYAMARGNYSRKVKVYGVDEI
GELADSFNTLTKRVQEAQAMTEGERRKLSSVLAYMTDGVIATDRRGKVILINTPAEKMLRVKHESANGRSIIDVLDIGDS
YQFEDLMEVDGSLTMDRSTLDKPYILRANFSVIQRETGFNNGVIAVLHDITDQEKVDQERRDFVSNVSHELRTPLTSMHS
YLEALSDGAWEDKEIAPRFLEVTQNETERMIRLVNDLLKLSRMDGGREHLEKSFVNFTDFFNHIIDRFEMMKKETIMFKR
HIPKEPVIIEIDEDKVMQVLDNIISNANKYSPDGGRISFYLKKFEDEIEISIADEGLGVPEEDLANVFDRFFRVDKARSR
EMGGTGLGLAIAREVIEAHGGRIWAERNKSKGTVIKFTLPYSDLPEDDWE
>Mature_610_residues
MHKMRFFQSVQFKLVIMYLLLIIVAMQVIGAYFVRELEGQLEKNFQNSITNSITLLDYNAREEIIKNSDNSVKLQNDIRE
LLVDFSRASSNLIEVRIVDEKGKILGTSNLNNQGIVGQKSNDPLVKRTLSLGTTSEDKIYKDESNKNNRVWVNVSSIKNK
GEVIGAIYLVADIESVYKQVDDITNIFITGTLIAMVITAILGILLSRTITKPIVEMKRQAYAMARGNYSRKVKVYGVDEI
GELADSFNTLTKRVQEAQAMTEGERRKLSSVLAYMTDGVIATDRRGKVILINTPAEKMLRVKHESANGRSIIDVLDIGDS
YQFEDLMEVDGSLTMDRSTLDKPYILRANFSVIQRETGFNNGVIAVLHDITDQEKVDQERRDFVSNVSHELRTPLTSMHS
YLEALSDGAWEDKEIAPRFLEVTQNETERMIRLVNDLLKLSRMDGGREHLEKSFVNFTDFFNHIIDRFEMMKKETIMFKR
HIPKEPVIIEIDEDKVMQVLDNIISNANKYSPDGGRISFYLKKFEDEIEISIADEGLGVPEEDLANVFDRFFRVDKARSR
EMGGTGLGLAIAREVIEAHGGRIWAERNKSKGTVIKFTLPYSDLPEDDWE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=365, Percent_Identity=27.6712328767123, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1788393, Length=228, Percent_Identity=32.8947368421053, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1790346, Length=247, Percent_Identity=33.6032388663968, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1786783, Length=240, Percent_Identity=29.1666666666667, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI145693157, Length=232, Percent_Identity=28.0172413793103, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=29.8701298701299, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788713, Length=232, Percent_Identity=26.2931034482759, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI48994928, Length=291, Percent_Identity=24.3986254295533, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788549, Length=377, Percent_Identity=24.6684350132626, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1789149, Length=231, Percent_Identity=25.5411255411255, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790551, Length=245, Percent_Identity=28.1632653061224, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082128, Length=237, Percent_Identity=26.5822784810127, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=27.3542600896861, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790861, Length=215, Percent_Identity=25.5813953488372, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787894, Length=230, Percent_Identity=25.2173913043478, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081816, Length=239, Percent_Identity=26.3598326359833, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1788279, Length=241, Percent_Identity=29.045643153527, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1787374, Length=219, Percent_Identity=26.9406392694064, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790300, Length=240, Percent_Identity=27.9166666666667, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789403, Length=206, Percent_Identity=27.6699029126214, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69484; Mature: 69484

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKMRFFQSVQFKLVIMYLLLIIVAMQVIGAYFVRELEGQLEKNFQNSITNSITLLDYNA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCH
REEIIKNSDNSVKLQNDIRELLVDFSRASSNLIEVRIVDEKGKILGTSNLNNQGIVGQKS
HHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCC
NDPLVKRTLSLGTTSEDKIYKDESNKNNRVWVNVSSIKNKGEVIGAIYLVADIESVYKQV
CCHHHHHHHHCCCCCCCCEECCCCCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHH
DDITNIFITGTLIAMVITAILGILLSRTITKPIVEMKRQAYAMARGNYSRKVKVYGVDEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHH
GELADSFNTLTKRVQEAQAMTEGERRKLSSVLAYMTDGVIATDRRGKVILINTPAEKMLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEECCHHHHHH
VKHESANGRSIIDVLDIGDSYQFEDLMEVDGSLTMDRSTLDKPYILRANFSVIQRETGFN
HHCCCCCCCEEEEEEECCCCCCHHHHHHCCCCCEECHHHCCCCEEEECCHHHHHHCCCCC
NGVIAVLHDITDQEKVDQERRDFVSNVSHELRTPLTSMHSYLEALSDGAWEDKEIAPRFL
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHH
EVTQNETERMIRLVNDLLKLSRMDGGREHLEKSFVNFTDFFNHIIDRFEMMKKETIMFKR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HIPKEPVIIEIDEDKVMQVLDNIISNANKYSPDGGRISFYLKKFEDEIEISIADEGLGVP
CCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCC
EEDLANVFDRFFRVDKARSREMGGTGLGLAIAREVIEAHGGRIWAERNKSKGTVIKFTLP
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECC
YSDLPEDDWE
CCCCCCCCCC
>Mature Secondary Structure
MHKMRFFQSVQFKLVIMYLLLIIVAMQVIGAYFVRELEGQLEKNFQNSITNSITLLDYNA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCH
REEIIKNSDNSVKLQNDIRELLVDFSRASSNLIEVRIVDEKGKILGTSNLNNQGIVGQKS
HHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCC
NDPLVKRTLSLGTTSEDKIYKDESNKNNRVWVNVSSIKNKGEVIGAIYLVADIESVYKQV
CCHHHHHHHHCCCCCCCCEECCCCCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHH
DDITNIFITGTLIAMVITAILGILLSRTITKPIVEMKRQAYAMARGNYSRKVKVYGVDEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHH
GELADSFNTLTKRVQEAQAMTEGERRKLSSVLAYMTDGVIATDRRGKVILINTPAEKMLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEECCHHHHHH
VKHESANGRSIIDVLDIGDSYQFEDLMEVDGSLTMDRSTLDKPYILRANFSVIQRETGFN
HHCCCCCCCEEEEEEECCCCCCHHHHHHCCCCCEECHHHCCCCEEEECCHHHHHHCCCCC
NGVIAVLHDITDQEKVDQERRDFVSNVSHELRTPLTSMHSYLEALSDGAWEDKEIAPRFL
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHH
EVTQNETERMIRLVNDLLKLSRMDGGREHLEKSFVNFTDFFNHIIDRFEMMKKETIMFKR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HIPKEPVIIEIDEDKVMQVLDNIISNANKYSPDGGRISFYLKKFEDEIEISIADEGLGVP
CCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCC
EEDLANVFDRFFRVDKARSREMGGTGLGLAIAREVIEAHGGRIWAERNKSKGTVIKFTLP
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECC
YSDLPEDDWE
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]