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The map label for this gene is yabD [H]

Identifier: 116871574

GI number: 116871574

Start: 154744

End: 155541

Strand: Direct

Name: yabD [H]

Synonym: lwe0154

Alternate gene names: 116871574

Gene position: 154744-155541 (Clockwise)

Preceding gene: 116871573

Following gene: 116871575

Centisome position: 5.5

GC content: 39.22

Gene sequence:

>798_bases
ATGATTTTATTAGGAGGAATTACTTTGCTATTTGATACGCATGTTCACCTCAATGACGAGGCTTTTGATGATGATATAGA
AGAAGTGATAAAACGCGCGCAGGAAAACGATGTGACACATATGGCCGTCGTAGGTTTTAATAAAGAGACAATTGATCGGG
CGCTTCTATTAGCTGATAAATATGATTTTATCTCACTAATCGTCGGCTGGCACCCTACAGATGCTATCACCTTCACAGAC
GAAGATTTAGAATGGTTGCGCGATTTAGCTCTTACACATCCAAAAGTAGTTGCTTTGGGCGAAATGGGCTTGGATTATCA
TTGGGACACTTCACCAAAAGAAACGCAATTCGAGGTTTTTAGAAAACAAATCCGTTTAGCTAAAGAAGTGAATTTACCGA
TAGTCATTCATAACCGTGAGGCAACAGAAGATGTTGTTCGTATTTTGCAAGAAGAGCATGCGGAAGAAGTAGGAGGAATA
ATGCACTGCTTTGGTGAAACTGTCGAAGTGATGGAAGCGTGCCTAGCAATGAATTTTTACATTTCCTTTGGAGGAACAGT
CACTTTCAAAAATGCAAAACTGCCAAAAATTGCGGCTCAAGCTATACCAATTGACCGAATGTTGATTGAAACAGACGCTC
CTTATTTAGCTCCAACTCCAAATCGTGGAAAAAGAAATGAACCAGCATACGTCAAGTTAGTTGCCGAAAAAATTGCAGAA
CTCAAAGAAATGAAATATAGCGAAATCGCCACGCACACAACAGCTAACGCAAAAAAATTATTTAAAATCCAAAAGTGA

Upstream 100 bases:

>100_bases
ATAGAAGTAATTAAATGAAGCTAAGAACAAAATCATTATATGTCTCGTCTATAATTTGTCATTTTTGTTTAGATGGAAAA
TTATAGTATAATAGAAGGAA

Downstream 100 bases:

>100_bases
TTGTAATAAAACTGTAACATAAGGGCGAGTCTGTAACCCAATCTTAAGCTTCGTGCAGATAAAAAAGACAGTTTAGGTCA
AAACCCTTATTTTATGCCTA

Product: TatD family deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MILLGGITLLFDTHVHLNDEAFDDDIEEVIKRAQENDVTHMAVVGFNKETIDRALLLADKYDFISLIVGWHPTDAITFTD
EDLEWLRDLALTHPKVVALGEMGLDYHWDTSPKETQFEVFRKQIRLAKEVNLPIVIHNREATEDVVRILQEEHAEEVGGI
MHCFGETVEVMEACLAMNFYISFGGTVTFKNAKLPKIAAQAIPIDRMLIETDAPYLAPTPNRGKRNEPAYVKLVAEKIAE
LKEMKYSEIATHTTANAKKLFKIQK

Sequences:

>Translated_265_residues
MILLGGITLLFDTHVHLNDEAFDDDIEEVIKRAQENDVTHMAVVGFNKETIDRALLLADKYDFISLIVGWHPTDAITFTD
EDLEWLRDLALTHPKVVALGEMGLDYHWDTSPKETQFEVFRKQIRLAKEVNLPIVIHNREATEDVVRILQEEHAEEVGGI
MHCFGETVEVMEACLAMNFYISFGGTVTFKNAKLPKIAAQAIPIDRMLIETDAPYLAPTPNRGKRNEPAYVKLVAEKIAE
LKEMKYSEIATHTTANAKKLFKIQK
>Mature_265_residues
MILLGGITLLFDTHVHLNDEAFDDDIEEVIKRAQENDVTHMAVVGFNKETIDRALLLADKYDFISLIVGWHPTDAITFTD
EDLEWLRDLALTHPKVVALGEMGLDYHWDTSPKETQFEVFRKQIRLAKEVNLPIVIHNREATEDVVRILQEEHAEEVGGI
MHCFGETVEVMEACLAMNFYISFGGTVTFKNAKLPKIAAQAIPIDRMLIETDAPYLAPTPNRGKRNEPAYVKLVAEKIAE
LKEMKYSEIATHTTANAKKLFKIQK

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=265, Percent_Identity=31.3207547169811, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI110349734, Length=265, Percent_Identity=31.6981132075472, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI226061853, Length=270, Percent_Identity=31.8518518518519, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI14042943, Length=266, Percent_Identity=30.0751879699248, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI226061614, Length=254, Percent_Identity=30.3149606299213, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI225903424, Length=164, Percent_Identity=37.1951219512195, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI226061595, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI225903439, Length=247, Percent_Identity=29.1497975708502, Blast_Score=99, Evalue=3e-21,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=40.3100775193798, Blast_Score=184, Evalue=4e-48,
Organism=Escherichia coli, GI48994985, Length=259, Percent_Identity=34.3629343629344, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=30.2325581395349, Blast_Score=121, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17559024, Length=282, Percent_Identity=32.2695035460993, Blast_Score=143, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=25.9541984732824, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17565396, Length=222, Percent_Identity=35.5855855855856, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17543026, Length=182, Percent_Identity=34.0659340659341, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24648690, Length=286, Percent_Identity=29.7202797202797, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI221330018, Length=273, Percent_Identity=30.4029304029304, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24586117, Length=273, Percent_Identity=30.4029304029304, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30076; Mature: 30076

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLGGITLLFDTHVHLNDEAFDDDIEEVIKRAQENDVTHMAVVGFNKETIDRALLLADK
CEEEEEEEEEEECEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCC
YDFISLIVGWHPTDAITFTDEDLEWLRDLALTHPKVVALGEMGLDYHWDTSPKETQFEVF
CCEEEEEEECCCCCEEEECCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHH
RKQIRLAKEVNLPIVIHNREATEDVVRILQEEHAEEVGGIMHCFGETVEVMEACLAMNFY
HHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
ISFGGTVTFKNAKLPKIAAQAIPIDRMLIETDAPYLAPTPNRGKRNEPAYVKLVAEKIAE
EEECCEEEECCCCCCHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LKEMKYSEIATHTTANAKKLFKIQK
HHHHHHHHHHHHCCCCHHHHHEECC
>Mature Secondary Structure
MILLGGITLLFDTHVHLNDEAFDDDIEEVIKRAQENDVTHMAVVGFNKETIDRALLLADK
CEEEEEEEEEEECEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCC
YDFISLIVGWHPTDAITFTDEDLEWLRDLALTHPKVVALGEMGLDYHWDTSPKETQFEVF
CCEEEEEEECCCCCEEEECCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHH
RKQIRLAKEVNLPIVIHNREATEDVVRILQEEHAEEVGGIMHCFGETVEVMEACLAMNFY
HHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
ISFGGTVTFKNAKLPKIAAQAIPIDRMLIETDAPYLAPTPNRGKRNEPAYVKLVAEKIAE
EEECCEEEECCCCCCHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LKEMKYSEIATHTTANAKKLFKIQK
HHHHHHHHHHHHCCCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]