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The map label for this gene is dppE [H]

Identifier: 116871558

GI number: 116871558

Start: 138068

End: 139717

Strand: Direct

Name: dppE [H]

Synonym: lwe0138

Alternate gene names: 116871558

Gene position: 138068-139717 (Clockwise)

Preceding gene: 116871557

Following gene: 116871559

Centisome position: 4.91

GC content: 36.73

Gene sequence:

>1650_bases
ATGAAAAAAAGAGTAGCGTTAATATGTATCATGATACTATCGATATCAACCTTTTTAATGGCATGTGGAGGAAATAAAGA
CGAAGCAAGCAAATCACAAGGCAAAAAGACATTAAAAATTATGGAAAACGCCGAAGTTTCTTCTATGGATTCTACTTTAT
CTCAAGATGTTCCGAGTTTTACCGAACAAGGCCAAGTGTTTGAAGGCTTATACACTTTGAATGACAAAGATCAAGCAGTT
CCAGCTATTGCAAAAGACATGCCAACCTTGAGCGAGGATCAAAAAACATATACGATTAAATTGCGAGATGATGCTAAATG
GTCAAACGGCACAAAAGTTACTGCAAATGACTTCATTTTTGCTTGGAAAAAATTAGCAAATCCCGATACTGCCGCGCAAT
ATTCATTTTTACTTGATGGTACAGTTAAGAATGGAACGGATGTAATTAACGGCAAGAAAAGTGTAGACGAATTAGGAATA
AAAGCGCTTGACGATTATACGATTGAAATTCAGTTAGAACAACCAGTTCCATATTTTACATCCCTGCTAGCTTTCAACTC
ATTCTATCCTCAAAATGAAGATTACGTGAAAGAGCAAGGAGAAAAATATGCGCAAAGCAGTGAAAATATGATTTACAACG
GTCCTTTTGTCATGAAAGGTTGGACCAACACTGAAAAAGCTTGGACTTTAGAAAAAAATCCTGAGTACTGGGATAAAAAG
AATGTGAAATCCGATAAAATCGAAGTAAGCGTAGTAAAAGCACCTAACACAGCGGTAAATCTATATGATACTGGAAAACT
TGATGTAGCAACACTTTCCGGTGATTATGCTTCCCAAAAAAGCAACGATAAAGATTACCATTCTGAACTAGATGCTTATG
TAACGCATCTAAAACTAAACCAAGAACTCGACGGTAAGAAAACGCCACTTGCTAATGAAAACTTACGAAAAGCTCTTTCT
CTAGCGGTAGACAAAGAATCGCTTACAAAGAAAATTTTAGCAGATGGATCTAAAGCGATTTATGGCTATGTCCCAGAAAA
ATTTGTCACCAATCCTGAAACGGGCGAAGATTTCCGTAAAGAAAGTGGCGACTACATGAAACAAGACAAAACGGAGGCAA
AAAGCTACTTTGACAAAGCAAAACAAGAACTTGGTGGAGGTGAAGTTACAGTAGAACTACTAAACTCTGATTTAGAATCA
AGTAAAAAAGTTGGCGAATATCTACAAAGTCAACTAGAATCGGCTTTGCCAGGGCTAAAAGTAAACTTAAAAACGGTTCC
TAAAAAGAACTTATTGCAATTAACACGAGAACAAAAATATGAAATCGTTCTGTCAAACTGGGGGCCGGATTTCCAAGATC
CACTAACGTTCTTAGGTAATTACACAACTGGCAACACATACAACGCTAGTGGTTATTCAAGCGCCGACTACGATAAAATG
ATTAATGCAACATCAACAACATTAACAACTCAACCAGAAAAACGCTGGGAGACTTTCATTGATGCAGAAAAACTTCTTAT
CGAAACAGATGCTGCTATGATTCCGCTATATCAAACGGCAGTATGTAATTTGAAAAAAGATACAGTAAAAGGAATTGTTC
ATCATAACTTTGGGACAAGCTTTTCCTATAAAGGTGCTTACGTAGAGTAG

Upstream 100 bases:

>100_bases
TAATACTGGGCTAGAAGCAAATGCGACGGCTTGGATGCAGATAATAGGGAAAGAATTATTTTCTGAAATGATAAATACCA
AATAATAAGGGGGAAACAAA

Downstream 100 bases:

>100_bases
AAGGAGAGAGTGAAATGAAACTTTGGATTTCAGTAGATATGGAAGGGATAAATGGTCTTCCAGATGATACTTTTGTTGAT
TCTAGTATGCGAAATTATAC

Product: solute-binding family 5 lipoprotein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MKKRVALICIMILSISTFLMACGGNKDEASKSQGKKTLKIMENAEVSSMDSTLSQDVPSFTEQGQVFEGLYTLNDKDQAV
PAIAKDMPTLSEDQKTYTIKLRDDAKWSNGTKVTANDFIFAWKKLANPDTAAQYSFLLDGTVKNGTDVINGKKSVDELGI
KALDDYTIEIQLEQPVPYFTSLLAFNSFYPQNEDYVKEQGEKYAQSSENMIYNGPFVMKGWTNTEKAWTLEKNPEYWDKK
NVKSDKIEVSVVKAPNTAVNLYDTGKLDVATLSGDYASQKSNDKDYHSELDAYVTHLKLNQELDGKKTPLANENLRKALS
LAVDKESLTKKILADGSKAIYGYVPEKFVTNPETGEDFRKESGDYMKQDKTEAKSYFDKAKQELGGGEVTVELLNSDLES
SKKVGEYLQSQLESALPGLKVNLKTVPKKNLLQLTREQKYEIVLSNWGPDFQDPLTFLGNYTTGNTYNASGYSSADYDKM
INATSTTLTTQPEKRWETFIDAEKLLIETDAAMIPLYQTAVCNLKKDTVKGIVHHNFGTSFSYKGAYVE

Sequences:

>Translated_549_residues
MKKRVALICIMILSISTFLMACGGNKDEASKSQGKKTLKIMENAEVSSMDSTLSQDVPSFTEQGQVFEGLYTLNDKDQAV
PAIAKDMPTLSEDQKTYTIKLRDDAKWSNGTKVTANDFIFAWKKLANPDTAAQYSFLLDGTVKNGTDVINGKKSVDELGI
KALDDYTIEIQLEQPVPYFTSLLAFNSFYPQNEDYVKEQGEKYAQSSENMIYNGPFVMKGWTNTEKAWTLEKNPEYWDKK
NVKSDKIEVSVVKAPNTAVNLYDTGKLDVATLSGDYASQKSNDKDYHSELDAYVTHLKLNQELDGKKTPLANENLRKALS
LAVDKESLTKKILADGSKAIYGYVPEKFVTNPETGEDFRKESGDYMKQDKTEAKSYFDKAKQELGGGEVTVELLNSDLES
SKKVGEYLQSQLESALPGLKVNLKTVPKKNLLQLTREQKYEIVLSNWGPDFQDPLTFLGNYTTGNTYNASGYSSADYDKM
INATSTTLTTQPEKRWETFIDAEKLLIETDAAMIPLYQTAVCNLKKDTVKGIVHHNFGTSFSYKGAYVE
>Mature_549_residues
MKKRVALICIMILSISTFLMACGGNKDEASKSQGKKTLKIMENAEVSSMDSTLSQDVPSFTEQGQVFEGLYTLNDKDQAV
PAIAKDMPTLSEDQKTYTIKLRDDAKWSNGTKVTANDFIFAWKKLANPDTAAQYSFLLDGTVKNGTDVINGKKSVDELGI
KALDDYTIEIQLEQPVPYFTSLLAFNSFYPQNEDYVKEQGEKYAQSSENMIYNGPFVMKGWTNTEKAWTLEKNPEYWDKK
NVKSDKIEVSVVKAPNTAVNLYDTGKLDVATLSGDYASQKSNDKDYHSELDAYVTHLKLNQELDGKKTPLANENLRKALS
LAVDKESLTKKILADGSKAIYGYVPEKFVTNPETGEDFRKESGDYMKQDKTEAKSYFDKAKQELGGGEVTVELLNSDLES
SKKVGEYLQSQLESALPGLKVNLKTVPKKNLLQLTREQKYEIVLSNWGPDFQDPLTFLGNYTTGNTYNASGYSSADYDKM
INATSTTLTTQPEKRWETFIDAEKLLIETDAAMIPLYQTAVCNLKKDTVKGIVHHNFGTSFSYKGAYVE

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=502, Percent_Identity=28.2868525896414, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI87081878, Length=535, Percent_Identity=27.2897196261682, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1789397, Length=479, Percent_Identity=28.6012526096033, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI1787762, Length=461, Percent_Identity=27.3318872017354, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787052, Length=348, Percent_Identity=25.8620689655172, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61408; Mature: 61408

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRVALICIMILSISTFLMACGGNKDEASKSQGKKTLKIMENAEVSSMDSTLSQDVPSF
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCHHHHHHHCCCCHHHHHHHHHHCCCCH
TEQGQVFEGLYTLNDKDQAVPAIAKDMPTLSEDQKTYTIKLRDDAKWSNGTKVTANDFIF
HHCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCEEECCHHHH
AWKKLANPDTAAQYSFLLDGTVKNGTDVINGKKSVDELGIKALDDYTIEIQLEQPVPYFT
HHHHHCCCCCHHEEEEEEECCCCCCCCCCCCCCCHHHHCCEEECCEEEEEEECCCCHHHH
SLLAFNSFYPQNEDYVKEQGEKYAQSSENMIYNGPFVMKGWTNTEKAWTLEKNPEYWDKK
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEECCCEEEECCCCCCCEEEECCCCCCCCCC
NVKSDKIEVSVVKAPNTAVNLYDTGKLDVATLSGDYASQKSNDKDYHSELDAYVTHLKLN
CCCCCCEEEEEEECCCCEEEEEECCCEEEEEECCCHHCCCCCCHHHHHHHHHHHHHHEEC
QELDGKKTPLANENLRKALSLAVDKESLTKKILADGSKAIYGYVPEKFVTNPETGEDFRK
CCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEECCCHHHCCCCCCCHHHHH
ESGDYMKQDKTEAKSYFDKAKQELGGGEVTVELLNSDLESSKKVGEYLQSQLESALPGLK
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHHHCCCCE
VNLKTVPKKNLLQLTREQKYEIVLSNWGPDFQDPLTFLGNYTTGNTYNASGYSSADYDKM
EEEEECCHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHH
INATSTTLTTQPEKRWETFIDAEKLLIETDAAMIPLYQTAVCNLKKDTVKGIVHHNFGTS
HCCCCCEEECCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCC
FSYKGAYVE
CCCCCCCCC
>Mature Secondary Structure
MKKRVALICIMILSISTFLMACGGNKDEASKSQGKKTLKIMENAEVSSMDSTLSQDVPSF
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCHHHHHHHCCCCHHHHHHHHHHCCCCH
TEQGQVFEGLYTLNDKDQAVPAIAKDMPTLSEDQKTYTIKLRDDAKWSNGTKVTANDFIF
HHCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCEEECCHHHH
AWKKLANPDTAAQYSFLLDGTVKNGTDVINGKKSVDELGIKALDDYTIEIQLEQPVPYFT
HHHHHCCCCCHHEEEEEEECCCCCCCCCCCCCCCHHHHCCEEECCEEEEEEECCCCHHHH
SLLAFNSFYPQNEDYVKEQGEKYAQSSENMIYNGPFVMKGWTNTEKAWTLEKNPEYWDKK
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEECCCEEEECCCCCCCEEEECCCCCCCCCC
NVKSDKIEVSVVKAPNTAVNLYDTGKLDVATLSGDYASQKSNDKDYHSELDAYVTHLKLN
CCCCCCEEEEEEECCCCEEEEEECCCEEEEEECCCHHCCCCCCHHHHHHHHHHHHHHEEC
QELDGKKTPLANENLRKALSLAVDKESLTKKILADGSKAIYGYVPEKFVTNPETGEDFRK
CCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEECCCHHHCCCCCCCHHHHH
ESGDYMKQDKTEAKSYFDKAKQELGGGEVTVELLNSDLESSKKVGEYLQSQLESALPGLK
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHHHCCCCE
VNLKTVPKKNLLQLTREQKYEIVLSNWGPDFQDPLTFLGNYTTGNTYNASGYSSADYDKM
EEEEECCHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHH
INATSTTLTTQPEKRWETFIDAEKLLIETDAAMIPLYQTAVCNLKKDTVKGIVHHNFGTS
HCCCCCEEECCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCC
FSYKGAYVE
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]