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The map label for this gene is adcB [H]

Identifier: 116871551

GI number: 116871551

Start: 130130

End: 130936

Strand: Direct

Name: adcB [H]

Synonym: lwe0131

Alternate gene names: 116871551

Gene position: 130130-130936 (Clockwise)

Preceding gene: 116871550

Following gene: 116871553

Centisome position: 4.62

GC content: 39.16

Gene sequence:

>807_bases
ATGGAAATGTTTCTCTATGGATTTATGCAAAGAGCCTTCCAAGCCTCAATGATTATTGCTATTATTGCACCTCTTTTAGG
GGTTTTCTTAATTATACGAAGACAGTCACTGATGGCGGATACGCTTTCGCATGTATCGCTTGCGGGTGTTGCTTTAGGAC
TGGTTTTAAATGTGAATCCCAGTGTGACAACTTTAATTATAGTAGTGATTGCGGCGCTTGGGATTGAGTATTTACGCGGA
GTTTATGCAACTTATTCGGAGTTATCGATTGCGATACTTATGGCTGGCGGGCTTGCTGTAGCGCTAGTTTTGATGAGTTT
AGATCAAGGTGGAATTACAACGAGTGTGCAGCAATATTTATTTGGTTCTATTGTGACAATAAGCAAGGCGCAAGTTCAGT
TGTTAGTGATTTTAGGTATTGCTATCATAGTACTGTTTCTTGTGTTTAAGCGGTTCATGTTTGTACTTACATTTAGTGAA
GATGTTGCGGTTGCAGAAGGAGTTCCCGTACGTTTGATTTCCCTTTTATTTAGTGTAGTTACTGGTATCGCTATTGCTGT
GATAATGCCAATAGCAGGGGCGCTTCTGGTGTCAGCACTTATTATACTACCGGCGGCAATTGGGATGCGTGTTTCGAAAG
GATTTTTGATGTGTGTTATTAGTGCGATTTTAATTGGGTTAGTTGGAATGTTTTCCGGATTAGTATCTTCCTATCAGCTC
GGAACTCCTCCTGGCGCAACGATTACTTTAATGTTTATTATACTTTTCATTATTTCAACTTTCATTTTAAAAATAGTACG
AAAATGA

Upstream 100 bases:

>100_bases
AGGTCCATAATAAAGCGATTTTAATGGTAACGCATGATAGTGAAGAAATGGAAGCTTATGTTGATAAACACATTCGCCTT
GTTAGAAAGGAGGATGTATC

Downstream 100 bases:

>100_bases
TTTTTTAAATAGATACTTGGCCATTTCGAATTTTAGCATTCAATTCTTTGTTGTAGATAATCCAAGTTTTATCTTGTTTT
TCAATTTGGTTAGTGATTTT

Product: zinc ABC transporter, permease protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MEMFLYGFMQRAFQASMIIAIIAPLLGVFLIIRRQSLMADTLSHVSLAGVALGLVLNVNPSVTTLIIVVIAALGIEYLRG
VYATYSELSIAILMAGGLAVALVLMSLDQGGITTSVQQYLFGSIVTISKAQVQLLVILGIAIIVLFLVFKRFMFVLTFSE
DVAVAEGVPVRLISLLFSVVTGIAIAVIMPIAGALLVSALIILPAAIGMRVSKGFLMCVISAILIGLVGMFSGLVSSYQL
GTPPGATITLMFIILFIISTFILKIVRK

Sequences:

>Translated_268_residues
MEMFLYGFMQRAFQASMIIAIIAPLLGVFLIIRRQSLMADTLSHVSLAGVALGLVLNVNPSVTTLIIVVIAALGIEYLRG
VYATYSELSIAILMAGGLAVALVLMSLDQGGITTSVQQYLFGSIVTISKAQVQLLVILGIAIIVLFLVFKRFMFVLTFSE
DVAVAEGVPVRLISLLFSVVTGIAIAVIMPIAGALLVSALIILPAAIGMRVSKGFLMCVISAILIGLVGMFSGLVSSYQL
GTPPGATITLMFIILFIISTFILKIVRK
>Mature_268_residues
MEMFLYGFMQRAFQASMIIAIIAPLLGVFLIIRRQSLMADTLSHVSLAGVALGLVLNVNPSVTTLIIVVIAALGIEYLRG
VYATYSELSIAILMAGGLAVALVLMSLDQGGITTSVQQYLFGSIVTISKAQVQLLVILGIAIIVLFLVFKRFMFVLTFSE
DVAVAEGVPVRLISLLFSVVTGIAIAVIMPIAGALLVSALIILPAAIGMRVSKGFLMCVISAILIGLVGMFSGLVSSYQL
GTPPGATITLMFIILFIISTFILKIVRK

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable). Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=248, Percent_Identity=32.258064516129, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 28458; Mature: 28458

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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CCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377 [H]