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The map label for this gene is adcA [H]

Identifier: 116871549

GI number: 116871549

Start: 128499

End: 129464

Strand: Direct

Name: adcA [H]

Synonym: lwe0129

Alternate gene names: 116871549

Gene position: 128499-129464 (Clockwise)

Preceding gene: 116871547

Following gene: 116871550

Centisome position: 4.57

GC content: 38.2

Gene sequence:

>966_bases
ATGAAGAAATGGTCGTTTATAGTTGTAGCAGTGTTAACATTCGCTTTAGTTTTGGCGGGATGTGGTGCTAGTAGCGATAA
AGTAAGTGGGGATAAGGACAAGCTTAAAATAGTGACCACTTTTTATCCTATGTATGATTTTACCAAGAATGTGGCGGGAG
ACAAGGCTTCTATTGAAATGTTGATTGATGCTGGAACAGAGCCGCATGATTACGAACCAAGTGCAAAAGATATTGCCAAA
ATCGAAGCAGCAGATGTATTTGTTTATAACAGTGAAGACATGGAAACATGGGTGCCAAGCGTGCTTAAAAGCTTAGACTC
AAAAAAATTGACCGTGATTGATGCTAGTAAAGGAATTCAGCTTGTAGAAGGAACCGAAGAAGAAGAACATCATGACCACG
AAGAAGAAGGGCACGATCATGATCATGAAGAAGCGCACCATCACGAACATGATCCACACGTATGGCTAAGTCCAGTTCTT
GCCCAACAAGAAGTAACCAATATCCAGAATGGTTTAACTAAAGCGGATAAAACAAATGCAGATACATATGAAAAGAATGC
AGCAAATTACAATGACAAACTAAAAGCCCTTGATGGCAAATTTAAAACAGCTTTTGAAGGAGCGAAACAACGCGATTTTG
TAACCCAACATGCCGCATTTCAGTATTTAGCAAAAGAATATAATCTTCACCAAGTAGCAATAGCCGGACTTTCACCTGAC
CAAGAACCAAGCCCTGCACGTTTAGCAGAATTACAAAAATACGTGAAAGACAACAACATCAGTACTATTTATTTTGAAGA
AGTAGCTTCCCCTAAAGTAGCGGAAACGCTTGCTAATGAAACTGGCGCAAAATTAGAAGTGTTAAGTCCAATTGAAGGAA
TTACTGACAAAGAACAGAAAAAAGGTATGGATTACATTGCTTATATGGGACAAAATCTAAAAGCCTTACAAAAAACAATT
AAATAA

Upstream 100 bases:

>100_bases
GTGCAAATAAGAATGATTACGTTTTGCGATGCGTAATCGAAATGTACATACTATAGTTTTAAGTTTTAAATCGTAATCAT
TACGAAAAAGGAGAGATAAT

Downstream 100 bases:

>100_bases
GGAAGCGATTAAATGAAATACATTGATATAGCCAATGTTGGTTTTAAATATGAATCCGAGCCAGTACTTGAAAACATTTC
TTTTCAGGTGAGTGCAGGAG

Product: zinc ABC transporter, zinc-binding lipoprotein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MKKWSFIVVAVLTFALVLAGCGASSDKVSGDKDKLKIVTTFYPMYDFTKNVAGDKASIEMLIDAGTEPHDYEPSAKDIAK
IEAADVFVYNSEDMETWVPSVLKSLDSKKLTVIDASKGIQLVEGTEEEEHHDHEEEGHDHDHEEAHHHEHDPHVWLSPVL
AQQEVTNIQNGLTKADKTNADTYEKNAANYNDKLKALDGKFKTAFEGAKQRDFVTQHAAFQYLAKEYNLHQVAIAGLSPD
QEPSPARLAELQKYVKDNNISTIYFEEVASPKVAETLANETGAKLEVLSPIEGITDKEQKKGMDYIAYMGQNLKALQKTI
K

Sequences:

>Translated_321_residues
MKKWSFIVVAVLTFALVLAGCGASSDKVSGDKDKLKIVTTFYPMYDFTKNVAGDKASIEMLIDAGTEPHDYEPSAKDIAK
IEAADVFVYNSEDMETWVPSVLKSLDSKKLTVIDASKGIQLVEGTEEEEHHDHEEEGHDHDHEEAHHHEHDPHVWLSPVL
AQQEVTNIQNGLTKADKTNADTYEKNAANYNDKLKALDGKFKTAFEGAKQRDFVTQHAAFQYLAKEYNLHQVAIAGLSPD
QEPSPARLAELQKYVKDNNISTIYFEEVASPKVAETLANETGAKLEVLSPIEGITDKEQKKGMDYIAYMGQNLKALQKTI
K
>Mature_321_residues
MKKWSFIVVAVLTFALVLAGCGASSDKVSGDKDKLKIVTTFYPMYDFTKNVAGDKASIEMLIDAGTEPHDYEPSAKDIAK
IEAADVFVYNSEDMETWVPSVLKSLDSKKLTVIDASKGIQLVEGTEEEEHHDHEEEGHDHDHEEAHHHEHDPHVWLSPVL
AQQEVTNIQNGLTKADKTNADTYEKNAANYNDKLKALDGKFKTAFEGAKQRDFVTQHAAFQYLAKEYNLHQVAIAGLSPD
QEPSPARLAELQKYVKDNNISTIYFEEVASPKVAETLANETGAKLEVLSPIEGITDKEQKKGMDYIAYMGQNLKALQKTI
K

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable) [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=257, Percent_Identity=21.011673151751, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 35765; Mature: 35765

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKWSFIVVAVLTFALVLAGCGASSDKVSGDKDKLKIVTTFYPMYDFTKNVAGDKASIEM
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHCCCCCCEEEE
LIDAGTEPHDYEPSAKDIAKIEAADVFVYNSEDMETWVPSVLKSLDSKKLTVIDASKGIQ
EEECCCCCCCCCCCHHHHHHHEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCEE
LVEGTEEEEHHDHEEEGHDHDHEEAHHHEHDPHVWLSPVLAQQEVTNIQNGLTKADKTNA
EECCCCHHHHCCCHHCCCCCCHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCC
DTYEKNAANYNDKLKALDGKFKTAFEGAKQRDFVTQHAAFQYLAKEYNLHQVAIAGLSPD
CHHHHCCCCCCHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
QEPSPARLAELQKYVKDNNISTIYFEEVASPKVAETLANETGAKLEVLSPIEGITDKEQK
CCCCHHHHHHHHHHHHCCCCEEEEEHHHCCCHHHHHHHHCCCCEEEEECCCCCCCCHHHH
KGMDYIAYMGQNLKALQKTIK
CCCHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure
MKKWSFIVVAVLTFALVLAGCGASSDKVSGDKDKLKIVTTFYPMYDFTKNVAGDKASIEM
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHCCCCCCEEEE
LIDAGTEPHDYEPSAKDIAKIEAADVFVYNSEDMETWVPSVLKSLDSKKLTVIDASKGIQ
EEECCCCCCCCCCCHHHHHHHEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCEE
LVEGTEEEEHHDHEEEGHDHDHEEAHHHEHDPHVWLSPVLAQQEVTNIQNGLTKADKTNA
EECCCCHHHHCCCHHCCCCCCHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCC
DTYEKNAANYNDKLKALDGKFKTAFEGAKQRDFVTQHAAFQYLAKEYNLHQVAIAGLSPD
CHHHHCCCCCCHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
QEPSPARLAELQKYVKDNNISTIYFEEVASPKVAETLANETGAKLEVLSPIEGITDKEQK
CCCCHHHHHHHHHHHHCCCCEEEEEHHHCCCHHHHHHHHCCCCEEEEECCCCCCCCHHHH
KGMDYIAYMGQNLKALQKTIK
CCCHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9811636 [H]