Click here to switch to the map view.

The map label for this gene is esxA [H]

Identifier: 116871469

GI number: 116871469

Start: 46748

End: 47041

Strand: Direct

Name: esxA [H]

Synonym: lwe0047

Alternate gene names: 116871469

Gene position: 46748-47041 (Clockwise)

Preceding gene: 116871468

Following gene: 116871470

Centisome position: 1.66

GC content: 39.46

Gene sequence:

>294_bases
ATGTCAGGTCAAATTAGAATGAGTCCGGCAGAGTTACGCGATCGCGCTAAAACTTATGGTCAGAGTGGTAGAGATATTGA
AGATATTTTAAGCCGTTTAAGCCAGTTACAAGAACAGCTTCGTAGCGAATGGGAAGGTCAAGCTTTTGCTCGTTTTGATG
AGCAATTTGAGCAATTAAGACCAAAAGTAACTGAATTTGCGAACTTAATGGATCAAATCAACGCTCAACTTGAGAAGACA
GCAAACGCAGTAGAAGAACACGATCAACAACTTTCTCAAAATTTCGGATTCTAA

Upstream 100 bases:

>100_bases
TATATTATTCGCTTTTCTGTCACATTTTATTTTGTGAATTCGTGATATAATTTTAAGGTGATATCTTATTCACAATAGAT
AATAAGAGGAGATGAAGTGA

Downstream 100 bases:

>100_bases
AATCAACAAAAGTGGAGCATACATACAAATATCGTTGGATGCTTTACGAAAAGCCATGCAGTTTTTTGCATGGCTTTTTC
TAAAATAGAAAACATATGCC

Product: WXG domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 97; Mature: 96

Protein sequence:

>97_residues
MSGQIRMSPAELRDRAKTYGQSGRDIEDILSRLSQLQEQLRSEWEGQAFARFDEQFEQLRPKVTEFANLMDQINAQLEKT
ANAVEEHDQQLSQNFGF

Sequences:

>Translated_97_residues
MSGQIRMSPAELRDRAKTYGQSGRDIEDILSRLSQLQEQLRSEWEGQAFARFDEQFEQLRPKVTEFANLMDQINAQLEKT
ANAVEEHDQQLSQNFGF
>Mature_96_residues
SGQIRMSPAELRDRAKTYGQSGRDIEDILSRLSQLQEQLRSEWEGQAFARFDEQFEQLRPKVTEFANLMDQINAQLEKTA
NAVEEHDQQLSQNFGF

Specific function: Virulence factor that is important for the establishment of infection in the host [H]

COG id: COG4842

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ESAT-6 (esx) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010310 [H]

Pfam domain/function: PF06013 WXG100 [H]

EC number: NA

Molecular weight: Translated: 11279; Mature: 11147

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQIRMSPAELRDRAKTYGQSGRDIEDILSRLSQLQEQLRSEWEGQAFARFDEQFEQLR
CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
PKVTEFANLMDQINAQLEKTANAVEEHDQQLSQNFGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGQIRMSPAELRDRAKTYGQSGRDIEDILSRLSQLQEQLRSEWEGQAFARFDEQFEQLR
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
PKVTEFANLMDQINAQLEKTANAVEEHDQQLSQNFGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA