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The map label for this gene is rhtC [H]

Identifier: 116696484

GI number: 116696484

Start: 2875608

End: 2876195

Strand: Direct

Name: rhtC [H]

Synonym: H16_B2548

Alternate gene names: 116696484

Gene position: 2875608-2876195 (Clockwise)

Preceding gene: 116696481

Following gene: 116696488

Centisome position: 98.73

GC content: 69.22

Gene sequence:

>588_bases
GTGACCGTGCTGGCCGTTGTCAGTCCGGGCCCGGACTTCGCCATGGTGACCCGCAACAGCTACCTGTACGGCCGCCGCGC
CGGCCTGCTCAGCGCCCTCGGAATCGCGCTGGGGGTGCAGGTGCATGTGCTCTATACGATGTTCGGGGTGGCGCTGCTGA
TGGCTCATGCGCACAGCATGCTGACGGTGGTGAAGATGCTGGGGGCGGCCTACCTGGTGTGGATCGGCGTCCAGACCCTG
CGCAACCGCGAGGCGCTGGCAGCAGACCTGCAAGGTGCGCGCACGCTGCGGCCGTGGGCGGCGCTGCGCATGGGCTTCCT
GACCAATGCGCTGAACCCGAAGACCACGCTGTTCGTGGTCAGCACCTACACCCAGGTGGTCGGTGCGCACACGCCGGTGC
CGGTGCAATGGGCTTATGGCGGATTCATGTCGGTGGCGCACCTGGCGTGGTTCAGCCTGGTGGCGTGCGTATTCACCGCG
CCGGCGCTGCGCGCGGCGATGCTGCGGCGCCAGCGGCTGCTGGACCGCACCATCGGCTCGGCCTTGTGCGGGCTGGGCGT
GGCGCTGGGGCTCAGCAACCTGGCGTAG

Upstream 100 bases:

>100_bases
TTGGGTACGCCCGGATCTCCCGATGTGGCGATCTCCGGATAATTACAACGTAACCTGACAGAAAATGCCCCCAATCGCCG
AATCCCTGGCGGTCGCCGCC

Downstream 100 bases:

>100_bases
GGCCAGCCTGCGTCAGTGGCCAGGCCTGGCGCACGAGATGCTGGGGACCTTGCGGGCCGAGCCGGCTTTCGAACAGCACC
AGCCGCTGCACGTGCCAGGG

Product: putative threonine efflux protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MTVLAVVSPGPDFAMVTRNSYLYGRRAGLLSALGIALGVQVHVLYTMFGVALLMAHAHSMLTVVKMLGAAYLVWIGVQTL
RNREALAADLQGARTLRPWAALRMGFLTNALNPKTTLFVVSTYTQVVGAHTPVPVQWAYGGFMSVAHLAWFSLVACVFTA
PALRAAMLRRQRLLDRTIGSALCGLGVALGLSNLA

Sequences:

>Translated_195_residues
MTVLAVVSPGPDFAMVTRNSYLYGRRAGLLSALGIALGVQVHVLYTMFGVALLMAHAHSMLTVVKMLGAAYLVWIGVQTL
RNREALAADLQGARTLRPWAALRMGFLTNALNPKTTLFVVSTYTQVVGAHTPVPVQWAYGGFMSVAHLAWFSLVACVFTA
PALRAAMLRRQRLLDRTIGSALCGLGVALGLSNLA
>Mature_194_residues
TVLAVVSPGPDFAMVTRNSYLYGRRAGLLSALGIALGVQVHVLYTMFGVALLMAHAHSMLTVVKMLGAAYLVWIGVQTLR
NREALAADLQGARTLRPWAALRMGFLTNALNPKTTLFVVSTYTQVVGAHTPVPVQWAYGGFMSVAHLAWFSLVACVFTAP
ALRAAMLRRQRLLDRTIGSALCGLGVALGLSNLA

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=194, Percent_Identity=29.3814432989691, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1786522, Length=181, Percent_Identity=29.2817679558011, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1788099, Length=189, Percent_Identity=25.9259259259259, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 20884; Mature: 20753

Theoretical pI: Translated: 11.32; Mature: 11.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLAVVSPGPDFAMVTRNSYLYGRRAGLLSALGIALGVQVHVLYTMFGVALLMAHAHSM
CEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTVVKMLGAAYLVWIGVQTLRNREALAADLQGARTLRPWAALRMGFLTNALNPKTTLFVV
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEH
STYTQVVGAHTPVPVQWAYGGFMSVAHLAWFSLVACVFTAPALRAAMLRRQRLLDRTIGS
HHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALCGLGVALGLSNLA
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVLAVVSPGPDFAMVTRNSYLYGRRAGLLSALGIALGVQVHVLYTMFGVALLMAHAHSM
EEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTVVKMLGAAYLVWIGVQTLRNREALAADLQGARTLRPWAALRMGFLTNALNPKTTLFVV
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEH
STYTQVVGAHTPVPVQWAYGGFMSVAHLAWFSLVACVFTAPALRAAMLRRQRLLDRTIGS
HHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALCGLGVALGLSNLA
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]