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The map label for this gene is narX2 [H]

Identifier: 116696269

GI number: 116696269

Start: 2643643

End: 2645667

Strand: Direct

Name: narX2 [H]

Synonym: H16_B2333

Alternate gene names: 116696269

Gene position: 2643643-2645667 (Clockwise)

Preceding gene: 116696267

Following gene: 116696270

Centisome position: 90.77

GC content: 71.16

Gene sequence:

>2025_bases
ATGTTCCGAACCGATCCTCCAGCCGCCAGCGCCGCGGCGGACTTCCGCGCTGCCGGCCTGTCGGCGCTGCGCGACCGCCT
CTCCACCCGCATCATCTCGCTCTCGCTGGCCGTGCTGCTGGTGGTGCTGGGCATGATTGCCGGCACGCTGTGGCTGTCAT
GGAAGCTGGAGGGCGCGGGTGCCGCCATCAATGACGCCGGCAGCCTGCGCATGCGCGCCAACCGCGTGGCGATCGAACTG
ACGCTGGCGCAGGCGCGCCAGGACAATGCACTGGCCGAGCAGGTGCAGGCGCTGGACGCCACGCTGGCCCTGCTCAGGAA
AGGCGACGCGGCGCGCCCGCTGTTCCTGCCGGACGAACCCGCCATCCATGCCCAGATGACCCGTGTCACGCAGGGCTGGC
AACAACGTCTGCGCCCGCTGGCGGTAGCCGGAACGGGCGAGCACGCAGCGCCGGCAAGCTATATCGCCGCACTGCCCGGC
TTCGTCGCGCAGGCCGATCGCCTGGTTGGCATGATCGAGCATGACAGCGCGCGCAAGACCGACTGGCTGCGCTTGTCGCA
GATCGCGCTGGCGGCAATGGCCTGCGTCGGCACCGTGGCCGTGATCTACCTGCTCTACCTGTGGATCATCCTGCCGGTGC
TGCGGCTGCAGGACGGCCTGCGGCGCATGGCCGCGCGCGAGTTCTCGCTGCGCCTGCCGGTGGAAAGCCGCGACGAGTTC
GGCACCCTCAGCGAAGGCTTCAACCGCATGGCCGGCGAACTGCAGGGGCTGTACCACGACCTGGAGACGCGCGTGGCACA
GAAGACCGCCGAGCTGGAACGCCAGAACCGCGACCTGGAGACGCTCTACGACATGGCCGCCTTCCTGAACCAGGCCGCCG
ATGCCGAGGCCATGGCGCGCGGCTTCCTGGAACGCGTGATGCGCCAGTTCGATGCCGATGGCGGCAGCGTGCGCGTGCTG
GACAGCCGCCATGGCAGGATGCACCTGCTGGCAGCCGCCGGCCTGCCGGCCGCGCTGGCAGAATCCGAATCCTGCGCGGC
GGCCAACGCCTGCCATTGCGGCGACGCCACGCGCGAGGCCGTGGTCGCCATCGTCGACCTGCGCGCGGCGCAGCGCCAGG
GCGCCGCCGGGGATGCCACGCCCTGCAGCCGCAACGGCTTCCAGTCGCTGGCGGCCTTCCGCATCGAAAGCCAGCGCGGC
GCCACCGGCGTGTTCGCGCTGCACTTCCGCACGCCGCGCGCGCTGCCCCCGTCAGACCGCCAGATGCTGGAAACACTGGG
CCAGCACCTTGGCACCGCGCTGGAACACCTGCGCCTGTCCGCGACCGCGCGCCAGCTGGCGGTGGTGGAAGAGCGCAACC
TGGTGGCGCAGGGCCTGCACGACAGCATTGCCCAGGGCCTGAACTACCTGAACCTGCAGGTGCAGCTGCTGGACGCCGCG
GTCGAACGCGACGACCTGGCCGAGACCCGTGAGATCGTGCCGATGCTGCGCCACGGCGTGGAAGAGAGCTACCAGGACGT
GCGCGAACTGCTGAACAACTTCCGCTCGCGGCTCGGCACCGGCGAGCTGCGACCGGCGGTGGAAGAGACCGTGGGCCGCT
TTCGGCGCCAGTGCCGCACCGAGGCCACGCTCGCCATTGACGAGAGCGGCGGCGCCTGGCCGCTGGCGCCGGAGCAGCAG
CTGCAGGTGCTGTTCATCCTGCAGGAGGCGCTCTCCAATGTGCGCAAGCACGCCATGGCGGCGCACGTGGCGGTGGCGCT
CAGCCACGGCCGCGATTTCCGGCTGGTGGTGCAGGACGACGGCGAGGGCTTCGATCCGGAGGAAATCGCCACGCGCGCCG
AAGCGCATATCGGCCTGAACATCATGCGCGAGCGCGCGGCGCGGCTGGGGGCGCAGCTGCACGTGCAGGCCCGCCCCGGC
CACGGCGTGCGCATCGAACTGGTGCTGCCCGCCGGCCGCTCTTCCGGCGCCCGCGAGTTCGCCGACACCCGCCCCGCCCC
CACGACCACCGAGACCCAGCCATGA

Upstream 100 bases:

>100_bases
GCGCAGGGAAAATTGCCCTCGATGCCAGCGCGCAGCCATGCACGCGCCGGCCGCCGGGCCACCACCCGGCTTCCCCCGAC
TGGTAGCCCCCGATACCGCC

Downstream 100 bases:

>100_bases
CCATCCGCATCCTGCTGATCGACGACCACACCCTGTTCCGCTCCGGCATCCGTGCGCTGCTGCAGCGGCAGGCCGACTTC
GAGATCGTCGACGAAGCCGC

Product: signal transduction histidine kinase,nitrate/nitrite-specific

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 674; Mature: 674

Protein sequence:

>674_residues
MFRTDPPAASAAADFRAAGLSALRDRLSTRIISLSLAVLLVVLGMIAGTLWLSWKLEGAGAAINDAGSLRMRANRVAIEL
TLAQARQDNALAEQVQALDATLALLRKGDAARPLFLPDEPAIHAQMTRVTQGWQQRLRPLAVAGTGEHAAPASYIAALPG
FVAQADRLVGMIEHDSARKTDWLRLSQIALAAMACVGTVAVIYLLYLWIILPVLRLQDGLRRMAAREFSLRLPVESRDEF
GTLSEGFNRMAGELQGLYHDLETRVAQKTAELERQNRDLETLYDMAAFLNQAADAEAMARGFLERVMRQFDADGGSVRVL
DSRHGRMHLLAAAGLPAALAESESCAAANACHCGDATREAVVAIVDLRAAQRQGAAGDATPCSRNGFQSLAAFRIESQRG
ATGVFALHFRTPRALPPSDRQMLETLGQHLGTALEHLRLSATARQLAVVEERNLVAQGLHDSIAQGLNYLNLQVQLLDAA
VERDDLAETREIVPMLRHGVEESYQDVRELLNNFRSRLGTGELRPAVEETVGRFRRQCRTEATLAIDESGGAWPLAPEQQ
LQVLFILQEALSNVRKHAMAAHVAVALSHGRDFRLVVQDDGEGFDPEEIATRAEAHIGLNIMRERAARLGAQLHVQARPG
HGVRIELVLPAGRSSGAREFADTRPAPTTTETQP

Sequences:

>Translated_674_residues
MFRTDPPAASAAADFRAAGLSALRDRLSTRIISLSLAVLLVVLGMIAGTLWLSWKLEGAGAAINDAGSLRMRANRVAIEL
TLAQARQDNALAEQVQALDATLALLRKGDAARPLFLPDEPAIHAQMTRVTQGWQQRLRPLAVAGTGEHAAPASYIAALPG
FVAQADRLVGMIEHDSARKTDWLRLSQIALAAMACVGTVAVIYLLYLWIILPVLRLQDGLRRMAAREFSLRLPVESRDEF
GTLSEGFNRMAGELQGLYHDLETRVAQKTAELERQNRDLETLYDMAAFLNQAADAEAMARGFLERVMRQFDADGGSVRVL
DSRHGRMHLLAAAGLPAALAESESCAAANACHCGDATREAVVAIVDLRAAQRQGAAGDATPCSRNGFQSLAAFRIESQRG
ATGVFALHFRTPRALPPSDRQMLETLGQHLGTALEHLRLSATARQLAVVEERNLVAQGLHDSIAQGLNYLNLQVQLLDAA
VERDDLAETREIVPMLRHGVEESYQDVRELLNNFRSRLGTGELRPAVEETVGRFRRQCRTEATLAIDESGGAWPLAPEQQ
LQVLFILQEALSNVRKHAMAAHVAVALSHGRDFRLVVQDDGEGFDPEEIATRAEAHIGLNIMRERAARLGAQLHVQARPG
HGVRIELVLPAGRSSGAREFADTRPAPTTTETQP
>Mature_674_residues
MFRTDPPAASAAADFRAAGLSALRDRLSTRIISLSLAVLLVVLGMIAGTLWLSWKLEGAGAAINDAGSLRMRANRVAIEL
TLAQARQDNALAEQVQALDATLALLRKGDAARPLFLPDEPAIHAQMTRVTQGWQQRLRPLAVAGTGEHAAPASYIAALPG
FVAQADRLVGMIEHDSARKTDWLRLSQIALAAMACVGTVAVIYLLYLWIILPVLRLQDGLRRMAAREFSLRLPVESRDEF
GTLSEGFNRMAGELQGLYHDLETRVAQKTAELERQNRDLETLYDMAAFLNQAADAEAMARGFLERVMRQFDADGGSVRVL
DSRHGRMHLLAAAGLPAALAESESCAAANACHCGDATREAVVAIVDLRAAQRQGAAGDATPCSRNGFQSLAAFRIESQRG
ATGVFALHFRTPRALPPSDRQMLETLGQHLGTALEHLRLSATARQLAVVEERNLVAQGLHDSIAQGLNYLNLQVQLLDAA
VERDDLAETREIVPMLRHGVEESYQDVRELLNNFRSRLGTGELRPAVEETVGRFRRQCRTEATLAIDESGGAWPLAPEQQ
LQVLFILQEALSNVRKHAMAAHVAVALSHGRDFRLVVQDDGEGFDPEEIATRAEAHIGLNIMRERAARLGAQLHVQARPG
HGVRIELVLPAGRSSGAREFADTRPAPTTTETQP

Specific function: Probable member of a two-component regulatory system. It is not known what protein it phosphorylates and in which regulatory pathway it acts, as the narL and other nar genes do not exist in H.influenzae [H]

COG id: COG3850

COG function: function code T; Signal transduction histidine kinase, nitrate/nitrite-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788812, Length=233, Percent_Identity=33.4763948497854, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1787474, Length=255, Percent_Identity=32.156862745098, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR016380
- InterPro:   IPR011712
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73364; Mature: 73364

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRTDPPAASAAADFRAAGLSALRDRLSTRIISLSLAVLLVVLGMIAGTLWLSWKLEGAG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
AAINDAGSLRMRANRVAIELTLAQARQDNALAEQVQALDATLALLRKGDAARPLFLPDEP
CEECCCCCCEEEECEEEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AIHAQMTRVTQGWQQRLRPLAVAGTGEHAAPASYIAALPGFVAQADRLVGMIEHDSARKT
CHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DWLRLSQIALAAMACVGTVAVIYLLYLWIILPVLRLQDGLRRMAAREFSLRLPVESRDEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCC
GTLSEGFNRMAGELQGLYHDLETRVAQKTAELERQNRDLETLYDMAAFLNQAADAEAMAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHH
GFLERVMRQFDADGGSVRVLDSRHGRMHLLAAAGLPAALAESESCAAANACHCGDATREA
HHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCHHHHCCCCCCCCCCCCCCCHHHHH
VVAIVDLRAAQRQGAAGDATPCSRNGFQSLAAFRIESQRGATGVFALHFRTPRALPPSDR
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHH
QMLETLGQHLGTALEHLRLSATARQLAVVEERNLVAQGLHDSIAQGLNYLNLQVQLLDAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VERDDLAETREIVPMLRHGVEESYQDVRELLNNFRSRLGTGELRPAVEETVGRFRRQCRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
EATLAIDESGGAWPLAPEQQLQVLFILQEALSNVRKHAMAAHVAVALSHGRDFRLVVQDD
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
GEGFDPEEIATRAEAHIGLNIMRERAARLGAQLHVQARPGHGVRIELVLPAGRSSGAREF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEECCCCCCCHHH
ADTRPAPTTTETQP
HCCCCCCCCCCCCC
>Mature Secondary Structure
MFRTDPPAASAAADFRAAGLSALRDRLSTRIISLSLAVLLVVLGMIAGTLWLSWKLEGAG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
AAINDAGSLRMRANRVAIELTLAQARQDNALAEQVQALDATLALLRKGDAARPLFLPDEP
CEECCCCCCEEEECEEEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AIHAQMTRVTQGWQQRLRPLAVAGTGEHAAPASYIAALPGFVAQADRLVGMIEHDSARKT
CHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DWLRLSQIALAAMACVGTVAVIYLLYLWIILPVLRLQDGLRRMAAREFSLRLPVESRDEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCC
GTLSEGFNRMAGELQGLYHDLETRVAQKTAELERQNRDLETLYDMAAFLNQAADAEAMAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHH
GFLERVMRQFDADGGSVRVLDSRHGRMHLLAAAGLPAALAESESCAAANACHCGDATREA
HHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCHHHHCCCCCCCCCCCCCCCHHHHH
VVAIVDLRAAQRQGAAGDATPCSRNGFQSLAAFRIESQRGATGVFALHFRTPRALPPSDR
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHH
QMLETLGQHLGTALEHLRLSATARQLAVVEERNLVAQGLHDSIAQGLNYLNLQVQLLDAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VERDDLAETREIVPMLRHGVEESYQDVRELLNNFRSRLGTGELRPAVEETVGRFRRQCRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
EATLAIDESGGAWPLAPEQQLQVLFILQEALSNVRKHAMAAHVAVALSHGRDFRLVVQDD
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
GEGFDPEEIATRAEAHIGLNIMRERAARLGAQLHVQARPGHGVRIELVLPAGRSSGAREF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEECCCCCCCHHH
ADTRPAPTTTETQP
HCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]