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The map label for this gene is arsB [H]

Identifier: 116695902

GI number: 116695902

Start: 2219873

End: 2221126

Strand: Direct

Name: arsB [H]

Synonym: H16_B1966

Alternate gene names: 116695902

Gene position: 2219873-2221126 (Clockwise)

Preceding gene: 116695901

Following gene: 116695903

Centisome position: 76.22

GC content: 72.81

Gene sequence:

>1254_bases
ATGTCCAGCCACGCCCCGCTGCTGATCTGGTCGGTCGCCGCGCTGACCACGGCCGGCGTCCTGTTCCGCCCGTTCCGCCT
GCCCGAAGCCTTCTGGGCCGCCGCCGGCGCCCTGCTGCTGTGCGTCACCGGCCTGATGACGCTGCCCGACGCGCTGGCGG
CGGTGCTGCGCGGCTACGACGTGTACCTGTTTCTCGCGGGCATGATGCTGATCTCCGAGCTGGCCCGCAAGACCGGGCTG
TTCGACCACGTCGCCGCGCTCGCCGTGCGCCGGGCGCGCGGTTCGGCGCCGCGGCTGTTCCTGATGGTGTACGGCTTCGG
CACGCTGGTGACGGCATTCATGTCCAACGACGCCACCGCCGTGGTGCTGACGCCCGCGGTGCTGGCCGCCACCCGCGCCG
CGCGGGTCCGGCATCCGCTGCCCTACTTGTACGCGTGCGCCTTCATCGCCAATGCCGCCAGCTTCGTGCTGCCGATCTCC
AACCCGGCCAACCTGGTCATCTTCGGCACACGCATGCCGCCGCTGGCGGGCTGGCTGGCGAGCTTCGCGCTGCCGTCGCT
GGCCGCGGTGCTGGCCACGCTGGCAGCGCTGTGGTGGACCCAGCGCGCGGCGCTGGCCGAGCCCATCGAACATGACGTGC
CGGTGCCGCCGCTGTCGCCGCAGGCCCGGCTGACCGCGCTGGGCATCGTGCTGACCGGGCTGATCCTGCTGGTGGCCTCG
CTGCGCGGCAACGACCTGGGCTGGCCGACCTGCGCGGCGGGCGTGGCCACGCTGCTGCTGGTCTGCGCGACCCGGCGCGA
GCTGCTGGTGCCGGCGCTGCGCGAGGTGTCATGGGGGGTGTTGCCGATGGTGGCGGGGCTGTTCGTGCTGGTCGCGGCAC
TGGAGCAGACCGTGGTGATCGGCCAGCTGGCCGATGCCGTCGCAGCGGCGTCGCGCGACGGCGGCGCACTGGCCCTGCTG
GGCGTGGGCGCGGTGGTGGCGCTGGCGGGCAATATCGCCAACAACCTGCCGGCCGGCCTGATCGCCGCCTCGGCGCTGGC
GGGCGGACATGCCTCGCATGCCGTGACCGGTGCCGTGCTGATCGGCATTGACCTTGGCCCCAACTTGTCCGTCACCGGCT
CGCTGGCCACGCTGCTGTGGCTCACGGCGCTGCGGCGCGAAGGGCATATGGTCAGCGCCGGCCAGTTCCTGCGCGTGGGG
GCCGTGGTGATGCCGGCAGCGATGCTGCCGGCACTGGCGCTTTTGCTGCTTTAG

Upstream 100 bases:

>100_bases
CAGCGAGACAACTGGCCTGCCGGCGCCCGGCGCTGCCACGCCGGCCGTCCCCGCGGACGCCAGGCTGTAGACTTCCGGCT
TTCCACTGTCCCCGATCCCG

Downstream 100 bases:

>100_bases
GCCGCTGGCTCAGCTGGTAGCGGCGTCATTGGCCGCGGGGGTGTTGGCGGCCTGCGGCAGGGGCCGGCGCAGGCCGGTCG
CGCCATGGCGCACGGCACTG

Product: anion permease ArsB

Products: ADP; phosphate; arsenite [Periplasm] [C]

Alternate protein names: Arsenic efflux pump protein [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSSHAPLLIWSVAALTTAGVLFRPFRLPEAFWAAAGALLLCVTGLMTLPDALAAVLRGYDVYLFLAGMMLISELARKTGL
FDHVAALAVRRARGSAPRLFLMVYGFGTLVTAFMSNDATAVVLTPAVLAATRAARVRHPLPYLYACAFIANAASFVLPIS
NPANLVIFGTRMPPLAGWLASFALPSLAAVLATLAALWWTQRAALAEPIEHDVPVPPLSPQARLTALGIVLTGLILLVAS
LRGNDLGWPTCAAGVATLLLVCATRRELLVPALREVSWGVLPMVAGLFVLVAALEQTVVIGQLADAVAAASRDGGALALL
GVGAVVALAGNIANNLPAGLIAASALAGGHASHAVTGAVLIGIDLGPNLSVTGSLATLLWLTALRREGHMVSAGQFLRVG
AVVMPAAMLPALALLLL

Sequences:

>Translated_417_residues
MSSHAPLLIWSVAALTTAGVLFRPFRLPEAFWAAAGALLLCVTGLMTLPDALAAVLRGYDVYLFLAGMMLISELARKTGL
FDHVAALAVRRARGSAPRLFLMVYGFGTLVTAFMSNDATAVVLTPAVLAATRAARVRHPLPYLYACAFIANAASFVLPIS
NPANLVIFGTRMPPLAGWLASFALPSLAAVLATLAALWWTQRAALAEPIEHDVPVPPLSPQARLTALGIVLTGLILLVAS
LRGNDLGWPTCAAGVATLLLVCATRRELLVPALREVSWGVLPMVAGLFVLVAALEQTVVIGQLADAVAAASRDGGALALL
GVGAVVALAGNIANNLPAGLIAASALAGGHASHAVTGAVLIGIDLGPNLSVTGSLATLLWLTALRREGHMVSAGQFLRVG
AVVMPAAMLPALALLLL
>Mature_416_residues
SSHAPLLIWSVAALTTAGVLFRPFRLPEAFWAAAGALLLCVTGLMTLPDALAAVLRGYDVYLFLAGMMLISELARKTGLF
DHVAALAVRRARGSAPRLFLMVYGFGTLVTAFMSNDATAVVLTPAVLAATRAARVRHPLPYLYACAFIANAASFVLPISN
PANLVIFGTRMPPLAGWLASFALPSLAAVLATLAALWWTQRAALAEPIEHDVPVPPLSPQARLTALGIVLTGLILLVASL
RGNDLGWPTCAAGVATLLLVCATRRELLVPALREVSWGVLPMVAGLFVLVAALEQTVVIGQLADAVAAASRDGGALALLG
VGAVVALAGNIANNLPAGLIAASALAGGHASHAVTGAVLIGIDLGPNLSVTGSLATLLWLTALRREGHMVSAGQFLRVGA
VVMPAAMLPALALLLL

Specific function: Involved in arsenical resistance. Thought to form the channel of an arsenite pump [H]

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsB family [H]

Homologues:

Organism=Escherichia coli, GI87082277, Length=425, Percent_Identity=29.6470588235294, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802 [H]

Pfam domain/function: PF02040 ArsB [H]

EC number: NA

Molecular weight: Translated: 42926; Mature: 42794

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSHAPLLIWSVAALTTAGVLFRPFRLPEAFWAAAGALLLCVTGLMTLPDALAAVLRGYD
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
VYLFLAGMMLISELARKTGLFDHVAALAVRRARGSAPRLFLMVYGFGTLVTAFMSNDATA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCEE
VVLTPAVLAATRAARVRHPLPYLYACAFIANAASFVLPISNPANLVIFGTRMPPLAGWLA
EEEHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHEEEECCCCCCEEEEECCCCHHHHHHH
SFALPSLAAVLATLAALWWTQRAALAEPIEHDVPVPPLSPQARLTALGIVLTGLILLVAS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRGNDLGWPTCAAGVATLLLVCATRRELLVPALREVSWGVLPMVAGLFVLVAALEQTVVI
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GQLADAVAAASRDGGALALLGVGAVVALAGNIANNLPAGLIAASALAGGHASHAVTGAVL
HHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHEEEE
IGIDLGPNLSVTGSLATLLWLTALRREGHMVSAGQFLRVGAVVMPAAMLPALALLLL
EEEECCCCCCCHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SSHAPLLIWSVAALTTAGVLFRPFRLPEAFWAAAGALLLCVTGLMTLPDALAAVLRGYD
CCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
VYLFLAGMMLISELARKTGLFDHVAALAVRRARGSAPRLFLMVYGFGTLVTAFMSNDATA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCEE
VVLTPAVLAATRAARVRHPLPYLYACAFIANAASFVLPISNPANLVIFGTRMPPLAGWLA
EEEHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHEEEECCCCCCEEEEECCCCHHHHHHH
SFALPSLAAVLATLAALWWTQRAALAEPIEHDVPVPPLSPQARLTALGIVLTGLILLVAS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRGNDLGWPTCAAGVATLLLVCATRRELLVPALREVSWGVLPMVAGLFVLVAALEQTVVI
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GQLADAVAAASRDGGALALLGVGAVVALAGNIANNLPAGLIAASALAGGHASHAVTGAVL
HHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHEEEE
IGIDLGPNLSVTGSLATLLWLTALRREGHMVSAGQFLRVGAVVMPAAMLPALALLLL
EEEECCCCCCCHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; arsenite [Cytoplasm]; H2O [C]

Specific reaction: ATP + arsenite [Cytoplasm] + H2O = ADP + phosphate + arsenite [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA