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The map label for this gene is leuE [H]

Identifier: 116695894

GI number: 116695894

Start: 2210993

End: 2211622

Strand: Direct

Name: leuE [H]

Synonym: H16_B1958

Alternate gene names: 116695894

Gene position: 2210993-2211622 (Clockwise)

Preceding gene: 116695892

Following gene: 116695895

Centisome position: 75.91

GC content: 67.62

Gene sequence:

>630_bases
ATGATTGCCCTGACCACCCTGTCGGTCTTCGCGGCGGCAGTGATGCTGCTGCTCCTGTCACCCGGCCCGAACATGGCCTT
CGTGATGGCACATGGCATCACCTATGGCCTTCGGGGCGGCGTTGCGACGGCACTGGGGATTGCCGTGGCCGACCTGATCC
TCACGGTCCTGACAGCCACCGGCATCACCGCCCTGGTGATGGCGTGGGCGCCGGCGTTCGACCTGATCCGCTATGCCGGC
GCGGCCTATCTGCTGTGGATGGCGGTCAAGGCGCTGCGGCAGCCGCTTGCGCTGAAAGAGGCAGTGGTGACGCAGGCGTC
GTTGCGCTCGGTGTTCGTGCGCGCCATGCTCAACAGCCTGCTCAATCCCAAGGCGCTGCTGTTCTTCATGGTCTTCCTGC
CGCAGTTCGTGGATCCCGGCAAGGGCGGCGTGGCCCGGCAGCTGCTCGTGCTTGGCCTGGTCCTGACGGTGATCGCCACC
GTGTTTCACGCATTGCTCGGCGCGGCTGGCGGCACCGTGCGCCGCTTCCTGTCACGCCATCCCAAGGCGGCAACACTGCA
GTCGCGCGGCCTGGCAGCCGTGCTGGTGCTGCTGGCGCTGCGGGTGGTGCTGACCTCACGCCCGGCCTGA

Upstream 100 bases:

>100_bases
AGCGCGCGTGGGCCATGCTTTGTATCTAGAACAATGCTTTGCGTGTATCAGGCCAGAAGAATAGCCTGCATGCCTAGTCA
ACGCTAACCATTTCCTGCAC

Downstream 100 bases:

>100_bases
ACCCGTTTCCCACGCAGAGCCCCTGATGTATATCGCAGCCTTTATTTACCGGCCCGGCCAGGCCGATGACGAGTTCCACC
GCCTTAGCGCCCTGATCGAC

Product: putative threonine efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MIALTTLSVFAAAVMLLLLSPGPNMAFVMAHGITYGLRGGVATALGIAVADLILTVLTATGITALVMAWAPAFDLIRYAG
AAYLLWMAVKALRQPLALKEAVVTQASLRSVFVRAMLNSLLNPKALLFFMVFLPQFVDPGKGGVARQLLVLGLVLTVIAT
VFHALLGAAGGTVRRFLSRHPKAATLQSRGLAAVLVLLALRVVLTSRPA

Sequences:

>Translated_209_residues
MIALTTLSVFAAAVMLLLLSPGPNMAFVMAHGITYGLRGGVATALGIAVADLILTVLTATGITALVMAWAPAFDLIRYAG
AAYLLWMAVKALRQPLALKEAVVTQASLRSVFVRAMLNSLLNPKALLFFMVFLPQFVDPGKGGVARQLLVLGLVLTVIAT
VFHALLGAAGGTVRRFLSRHPKAATLQSRGLAAVLVLLALRVVLTSRPA
>Mature_209_residues
MIALTTLSVFAAAVMLLLLSPGPNMAFVMAHGITYGLRGGVATALGIAVADLILTVLTATGITALVMAWAPAFDLIRYAG
AAYLLWMAVKALRQPLALKEAVVTQASLRSVFVRAMLNSLLNPKALLFFMVFLPQFVDPGKGGVARQLLVLGLVLTVIAT
VFHALLGAAGGTVRRFLSRHPKAATLQSRGLAAVLVLLALRVVLTSRPA

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=189, Percent_Identity=29.6296296296296, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI48994979, Length=148, Percent_Identity=31.7567567567568, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI1786522, Length=191, Percent_Identity=29.8429319371728, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21941; Mature: 21941

Theoretical pI: Translated: 12.23; Mature: 12.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALTTLSVFAAAVMLLLLSPGPNMAFVMAHGITYGLRGGVATALGIAVADLILTVLTAT
CCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GITALVMAWAPAFDLIRYAGAAYLLWMAVKALRQPLALKEAVVTQASLRSVFVRAMLNSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNPKALLFFMVFLPQFVDPGKGGVARQLLVLGLVLTVIATVFHALLGAAGGTVRRFLSRH
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
PKAATLQSRGLAAVLVLLALRVVLTSRPA
CCHHHHHHCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIALTTLSVFAAAVMLLLLSPGPNMAFVMAHGITYGLRGGVATALGIAVADLILTVLTAT
CCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GITALVMAWAPAFDLIRYAGAAYLLWMAVKALRQPLALKEAVVTQASLRSVFVRAMLNSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNPKALLFFMVFLPQFVDPGKGGVARQLLVLGLVLTVIATVFHALLGAAGGTVRRFLSRH
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
PKAATLQSRGLAAVLVLLALRVVLTSRPA
CCHHHHHHCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA