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The map label for this gene is yhcS [C]

Identifier: 116695858

GI number: 116695858

Start: 2171994

End: 2172902

Strand: Direct

Name: yhcS [C]

Synonym: H16_B1922

Alternate gene names: 116695858

Gene position: 2171994-2172902 (Clockwise)

Preceding gene: 116695855

Following gene: 116695859

Centisome position: 74.58

GC content: 68.54

Gene sequence:

>909_bases
TTGCATCCCGACCTGAATGACCTGTATTACTTCGCGCAGGTAGTCGATCACCAGGGCTTTGCGCCCGCCGGGCGCGTGCT
CGGCATACCCAAGTCCAAGCTGAGCCGGCGCGTGGCGATGCTGGAAGAACGCCTGGGCGTGCGCCTGATCCAGCGCTCGA
CGCGGCGCTTCTCCGTGACAGAACTGGGGCAGACGTACTACGCCCATTGCAAGGCCATGCTGGTGGAGGCCGAAGCGGCC
GAGAGCGCGATCGAGCAAACCCGCGCCGAACCCAGCGGCCTGGTGCGCATGAGCTGCCCGGTGGCGCTGCTGCACGCACG
GGTGGGCGACATGATTGCGGATTTCATGGCGGCCAACCCCAAGGTCATCGTGCACCTGGAAGCCACCAACCGGCGCGTGG
ACGTGGTGGCGGAGGGGATCGACCTGGCCATCCGCGTGCGCGTGCCGCCACTCGAAGACAGCGACCTGGTGATGCGCGTG
CTGGCCGAGCGCGCCTGGTGCTTCGTGGCCAGCCCGGCGCTGCTGGCCGGCCATGGGCCGCTGCTGGCACCCGCGGACCT
CAACGTGCTGCCAACGCTGGACCTGGGGCCGCCGCGCCCCTCGCACACCTGGTCGCTATACGGCCCCGATGGCGCCAGCG
CCGAGCTGCACCACAAGCCCCGCCTGGTCACCGACGACATGATCATGCTGCGCACCGCGGCCGTGGCCGGTGCCGGCATC
GTGCAGCTGCCGGTCATGATGATGACCGACCAGCTGCGCGATGGCCGGCTGGTAAAAGTCCTGCCGGACTGGTCGGTCAG
GGGCGGCGTGATCCACGCCGTGTTCCCGTCACGGCGCGGGCTGCTGCCTTCGGTGCGTGAACTGATCGACTTCCTGTCGC
AGCGCTTCGCGCAGATCAGCGAACTCTAG

Upstream 100 bases:

>100_bases
GCCGACCGTGTGGCCAAAGCATAGGTCTTGGCAAATCGCATCGCTAGGATGGAAAATCTGCCCTCAGCGTCCTACTGGCA
GGACGACAGGAGCCGCCCGC

Downstream 100 bases:

>100_bases
GCATCGCAAGGCGGCCGCGCCAGGGGCACTGCCCGTCACGCGGGCAGGATTGGCCCGGAAGTGGTATCATCCAGGATCCT
ATGCACGGATCGGCAACGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MHPDLNDLYYFAQVVDHQGFAPAGRVLGIPKSKLSRRVAMLEERLGVRLIQRSTRRFSVTELGQTYYAHCKAMLVEAEAA
ESAIEQTRAEPSGLVRMSCPVALLHARVGDMIADFMAANPKVIVHLEATNRRVDVVAEGIDLAIRVRVPPLEDSDLVMRV
LAERAWCFVASPALLAGHGPLLAPADLNVLPTLDLGPPRPSHTWSLYGPDGASAELHHKPRLVTDDMIMLRTAAVAGAGI
VQLPVMMMTDQLRDGRLVKVLPDWSVRGGVIHAVFPSRRGLLPSVRELIDFLSQRFAQISEL

Sequences:

>Translated_302_residues
MHPDLNDLYYFAQVVDHQGFAPAGRVLGIPKSKLSRRVAMLEERLGVRLIQRSTRRFSVTELGQTYYAHCKAMLVEAEAA
ESAIEQTRAEPSGLVRMSCPVALLHARVGDMIADFMAANPKVIVHLEATNRRVDVVAEGIDLAIRVRVPPLEDSDLVMRV
LAERAWCFVASPALLAGHGPLLAPADLNVLPTLDLGPPRPSHTWSLYGPDGASAELHHKPRLVTDDMIMLRTAAVAGAGI
VQLPVMMMTDQLRDGRLVKVLPDWSVRGGVIHAVFPSRRGLLPSVRELIDFLSQRFAQISEL
>Mature_302_residues
MHPDLNDLYYFAQVVDHQGFAPAGRVLGIPKSKLSRRVAMLEERLGVRLIQRSTRRFSVTELGQTYYAHCKAMLVEAEAA
ESAIEQTRAEPSGLVRMSCPVALLHARVGDMIADFMAANPKVIVHLEATNRRVDVVAEGIDLAIRVRVPPLEDSDLVMRV
LAERAWCFVASPALLAGHGPLLAPADLNVLPTLDLGPPRPSHTWSLYGPDGASAELHHKPRLVTDDMIMLRTAAVAGAGI
VQLPVMMMTDQLRDGRLVKVLPDWSVRGGVIHAVFPSRRGLLPSVRELIDFLSQRFAQISEL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=298, Percent_Identity=29.8657718120805, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=30.7432432432432, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI87081978, Length=299, Percent_Identity=30.1003344481605, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI145693193, Length=284, Percent_Identity=27.112676056338, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787128, Length=296, Percent_Identity=25.6756756756757, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1789440, Length=296, Percent_Identity=25.3378378378378, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789173, Length=275, Percent_Identity=26.9090909090909, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787589, Length=297, Percent_Identity=23.9057239057239, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33192; Mature: 33192

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPDLNDLYYFAQVVDHQGFAPAGRVLGIPKSKLSRRVAMLEERLGVRLIQRSTRRFSVT
CCCCHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHH
ELGQTYYAHCKAMLVEAEAAESAIEQTRAEPSGLVRMSCPVALLHARVGDMIADFMAANP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCC
KVIVHLEATNRRVDVVAEGIDLAIRVRVPPLEDSDLVMRVLAERAWCFVASPALLAGHGP
EEEEEEECCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEECCHHEECCCC
LLAPADLNVLPTLDLGPPRPSHTWSLYGPDGASAELHHKPRLVTDDMIMLRTAAVAGAGI
EECCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCH
VQLPVMMMTDQLRDGRLVKVLPDWSVRGGVIHAVFPSRRGLLPSVRELIDFLSQRFAQIS
HHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
EL
CC
>Mature Secondary Structure
MHPDLNDLYYFAQVVDHQGFAPAGRVLGIPKSKLSRRVAMLEERLGVRLIQRSTRRFSVT
CCCCHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHH
ELGQTYYAHCKAMLVEAEAAESAIEQTRAEPSGLVRMSCPVALLHARVGDMIADFMAANP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCC
KVIVHLEATNRRVDVVAEGIDLAIRVRVPPLEDSDLVMRVLAERAWCFVASPALLAGHGP
EEEEEEECCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEECCHHEECCCC
LLAPADLNVLPTLDLGPPRPSHTWSLYGPDGASAELHHKPRLVTDDMIMLRTAAVAGAGI
EECCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCH
VQLPVMMMTDQLRDGRLVKVLPDWSVRGGVIHAVFPSRRGLLPSVRELIDFLSQRFAQIS
HHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
EL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]