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The map label for this gene is benK [H]

Identifier: 116695855

GI number: 116695855

Start: 2169006

End: 2170364

Strand: Direct

Name: benK [H]

Synonym: H16_B1919

Alternate gene names: 116695855

Gene position: 2169006-2170364 (Clockwise)

Preceding gene: 116695854

Following gene: 116695858

Centisome position: 74.47

GC content: 66.74

Gene sequence:

>1359_bases
ATGCGTCAGATCGATGTCCACAAGCTGGCCGACGAGGCCCGCTTCAACCGCTTCCATGCGCTCATCCTGTTCTGGTGTGC
GCTGATCATCATCTTCGACGGCTACGACCTGGCCGTGGCCGGCATCGCCCTGCCGTCGATCATGAAAGAGATGGGCGTGA
CCGCAACCAGCGCCGGCTTCATGGTCAGCTCGGCGCTGTTCGGCATGATGTTCGGCGCGATCTTCCTCGGCACCGTGGCC
GACCGCATCGGCCGCAGGCGCGCCATCGCCATCTGCATCGTGCTGTTCAGTGTCTTCACCGCGGCGGCGGGCTTTACCAG
CGACCCGGTGACGTTCAGCGTCACGCGCTTCCTGGCGGGCCTGGGCATCGGCGGCGTGATGCCCAACGTGGTGGCGCAGA
TGACCGAGTACTCGCCGCGCAAGCTGCGCGGCACGCTGGTGACGCTGATGTTCAGCGGTTATTCGGTGGGCGGCATGCTG
GCCGCGCTGCTGGGCAAGGGACTGATCGAAAGCTATGGCTGGCAGTCGGTGTTCCTCGCCGCCGGCCTGCCGGTGCTGCT
GGTCCCGCTGGTGCTGCGCTCGCTGCCGGAGTCGATGCCCTACCTGCTCCGCACCGGCCAGACCGACGCTCTGCAATCCG
TGGTATCGCGCCTGGTGCCGTCGCATCGCGCGCAAGCCGGCGACGTCTTTACGCTGGCTGCGGACGACAAGGCCGGCAGC
GCGCCGATCCGCCGCCTGTTCCAGGACGGCCGCGGCTTCAGCACGGTGATGTTCTGGGTGGCGTTCTTCATGTGCCTGTT
CATGGTGTACGCGCTCAGCTCGTGGCTGACCAAGCTGATGGCCGGCGCAGGCTACAGCCTGGGCTCGGCGCTGACTTTCG
TGCTGGTGCTGAACTTCGGCGCCATGCTCGGCGCCATCGGCGGCGGCTGGCTGGCCGACCGCTTGCCGATCAAGCATGTG
CTGATCGGCATGTACACGCTGGCGGCAGTGTCGATCACGCTGCTGGGCTACCCGATGCCCAGCGCAGCGCTGTTCGTCGT
GGTGGGCCTGGCAGGTGCTTCCACCATCGGCACGCAGATCGTCACCTATGCCTATGCGGGCCAGTTCTATCCGATGGCGG
TGCGCGGCACCGGCATCGGCTGGGCGTCCGGCGTGGGACGCAGCGGCGCCATCCTGGCACCGATCGTGATCGGCGTGCTG
GTTGGGATGTCGTTGCCGTTGCAGCAGAACTTCATGGCGATGGCGATTCCGGCGGTGATTGCAGTGGGGGCGGTGTCGAT
GATCAACCACCGGAGGTCGGCGTCGGCGCAGGCGGAAGTCGCTGCGGCGCCGGTGCGAGGAACTGTGAAGGAAGCCTGA

Upstream 100 bases:

>100_bases
TGCGCGAACGCGAACTGAAGGCCGCCGCAGAGCGCGCCGTCGCGGCGGCGTGAGCGGCAACGCCGCCCGCCCCGTCATAC
CACCATACCGGAGACAAACC

Downstream 100 bases:

>100_bases
GAGAAGTCAACCGCCAGTTGTTCGCTCCCTCTCCCGCTTGCGGGAGAGGAAGCGAACCGGCAGCGCTGAAAAGGACGTAG
CTTACTTGCTGCCCTTCACC

Product: major facilitator superfamily transporter AAHS family protein

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MRQIDVHKLADEARFNRFHALILFWCALIIIFDGYDLAVAGIALPSIMKEMGVTATSAGFMVSSALFGMMFGAIFLGTVA
DRIGRRRAIAICIVLFSVFTAAAGFTSDPVTFSVTRFLAGLGIGGVMPNVVAQMTEYSPRKLRGTLVTLMFSGYSVGGML
AALLGKGLIESYGWQSVFLAAGLPVLLVPLVLRSLPESMPYLLRTGQTDALQSVVSRLVPSHRAQAGDVFTLAADDKAGS
APIRRLFQDGRGFSTVMFWVAFFMCLFMVYALSSWLTKLMAGAGYSLGSALTFVLVLNFGAMLGAIGGGWLADRLPIKHV
LIGMYTLAAVSITLLGYPMPSAALFVVVGLAGASTIGTQIVTYAYAGQFYPMAVRGTGIGWASGVGRSGAILAPIVIGVL
VGMSLPLQQNFMAMAIPAVIAVGAVSMINHRRSASAQAEVAAAPVRGTVKEA

Sequences:

>Translated_452_residues
MRQIDVHKLADEARFNRFHALILFWCALIIIFDGYDLAVAGIALPSIMKEMGVTATSAGFMVSSALFGMMFGAIFLGTVA
DRIGRRRAIAICIVLFSVFTAAAGFTSDPVTFSVTRFLAGLGIGGVMPNVVAQMTEYSPRKLRGTLVTLMFSGYSVGGML
AALLGKGLIESYGWQSVFLAAGLPVLLVPLVLRSLPESMPYLLRTGQTDALQSVVSRLVPSHRAQAGDVFTLAADDKAGS
APIRRLFQDGRGFSTVMFWVAFFMCLFMVYALSSWLTKLMAGAGYSLGSALTFVLVLNFGAMLGAIGGGWLADRLPIKHV
LIGMYTLAAVSITLLGYPMPSAALFVVVGLAGASTIGTQIVTYAYAGQFYPMAVRGTGIGWASGVGRSGAILAPIVIGVL
VGMSLPLQQNFMAMAIPAVIAVGAVSMINHRRSASAQAEVAAAPVRGTVKEA
>Mature_452_residues
MRQIDVHKLADEARFNRFHALILFWCALIIIFDGYDLAVAGIALPSIMKEMGVTATSAGFMVSSALFGMMFGAIFLGTVA
DRIGRRRAIAICIVLFSVFTAAAGFTSDPVTFSVTRFLAGLGIGGVMPNVVAQMTEYSPRKLRGTLVTLMFSGYSVGGML
AALLGKGLIESYGWQSVFLAAGLPVLLVPLVLRSLPESMPYLLRTGQTDALQSVVSRLVPSHRAQAGDVFTLAADDKAGS
APIRRLFQDGRGFSTVMFWVAFFMCLFMVYALSSWLTKLMAGAGYSLGSALTFVLVLNFGAMLGAIGGGWLADRLPIKHV
LIGMYTLAAVSITLLGYPMPSAALFVVVGLAGASTIGTQIVTYAYAGQFYPMAVRGTGIGWASGVGRSGAILAPIVIGVL
VGMSLPLQQNFMAMAIPAVIAVGAVSMINHRRSASAQAEVAAAPVRGTVKEA

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI7662270, Length=241, Percent_Identity=27.8008298755187, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI24308167, Length=397, Percent_Identity=23.4256926952141, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI73695465, Length=260, Percent_Identity=27.3076923076923, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI216548223, Length=229, Percent_Identity=29.2576419213974, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI262399383, Length=182, Percent_Identity=28.021978021978, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI166064021, Length=369, Percent_Identity=24.6612466124661, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI213021148, Length=223, Percent_Identity=22.4215246636771, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI31542327, Length=356, Percent_Identity=23.314606741573, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI24497497, Length=379, Percent_Identity=28.2321899736148, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI8923870, Length=376, Percent_Identity=24.468085106383, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87081723, Length=411, Percent_Identity=30.6569343065693, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1786229, Length=394, Percent_Identity=27.1573604060914, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082231, Length=442, Percent_Identity=25.1131221719457, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082159, Length=391, Percent_Identity=29.6675191815857, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI87082404, Length=378, Percent_Identity=24.3386243386243, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788074, Length=384, Percent_Identity=26.0416666666667, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788068, Length=424, Percent_Identity=22.1698113207547, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1790463, Length=222, Percent_Identity=25.2252252252252, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=426, Percent_Identity=22.7699530516432, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17560496, Length=373, Percent_Identity=21.4477211796247, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19922874, Length=403, Percent_Identity=24.8138957816377, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24640198, Length=237, Percent_Identity=26.1603375527426, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24640196, Length=237, Percent_Identity=26.1603375527426, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24640200, Length=237, Percent_Identity=26.1603375527426, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47625; Mature: 47625

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS00120 LIPASE_SER ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]