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The map label for this gene is 116695714

Identifier: 116695714

GI number: 116695714

Start: 2016672

End: 2017991

Strand: Direct

Name: 116695714

Synonym: H16_B1778

Alternate gene names: NA

Gene position: 2016672-2017991 (Clockwise)

Preceding gene: 116695713

Following gene: 116695719

Centisome position: 69.24

GC content: 65.0

Gene sequence:

>1320_bases
ATGAAACTCCACGCAACACGCACGGCACCTGCCATCGCCACGATCGCTTTATGCCTGGCTCAATTGGCCTTGCCAAGCCA
CGCCCAGGCATCGCCGGCCGCCGAAGGCGGCGCAATCCCGCAACGCGCGGCGACCGAGGACGCATCCATTCGCCCCTTCC
ACGCCAGCTTCCCGCAAGCGGCACTGGCCGACCTGCGCCAGCGCATCGCCGCCACGCGCTGGCCAGACCGCGAGACGGTA
TCCGATCAATCGCAGGGCGTGCAGCTGGCGAAGATCCAGGAGCTGGTGCGCTATTGGGGCAACGACTACGACTGGTTCAA
GGCAGAGCAAAAGCTGAACGCCTACCCCCAGTTCGTCACCAGGATCGACGGGCTCGACATCCACTTCCTGCATGTGCGAT
CGCGCCATCCCAATGCGCTGCCGCTCGTCATCACCCACGGCTGGCCGGGCTCGGTCTTTGAACTGCTGAAGGTGATTGGC
CCGCTCACCGATCCCACCGCCTACGGCGGCCGTGCCGAGGACGCCTTCGATGTGGTGATTCCGTCGATGCCCGGCTACGG
CTTCTCCGGCAAACCCGTCGGGACCGGCTGGGGTCCCGACCGCATTGCAGGTGCGTGGGATGTGTTGATGAAGCGGCTGG
GCTACACACGTTATGTGTCACAGGGCGGCGACTGGGGCTCGGTCGTGGCGCATGCGCAGGGCCGCCAGGCACCACAGGGC
TTGCTCGGCATTCACGTCAATATGCCCGCCACCGTGCCAGCGGACGTCGCCCGGGCGCTGAAGAACGGCGAAGCAGCGCC
GGCCGGCCTGTCCGCCGCCGAAAGGTCAGCCTTCGAGTCGATGAACAAGTTGTATACGCTGGGCGGCGGCTATGCCGCGA
TGATGGTGACCCGCCCGCAGACCGTGGGCTATGGCCTGGCGGATTCCCCCGCAGGGCAGGCGGCATGGATCTATGACAAG
TTTGCCGCCTGGACCTTCAGCGGTGGCAACCCCGAGCGCTCGCTGACCAGGGACGAGATGCTCGACGACATCACGCTCTA
CTGGCTCACCAACAGCGCCACGTCGTCAGCACAGCTATATTGGGAAAACAACACCAACAACTTCAACGCCGCCGAGCAGA
TGACCGCACAGATCAAGGTGCCTGTAGGCGTGACGGTATTTCCCGGCGAGCTCTATCAAGCCCCGCGCAGCTGGGCCGAG
CGCGCCTACCCCCGGCTGACCTACTTCAACAAGGTCGACAAGGGGGGGCACTTCGCGGCATGGGAAGAGCCGCAGCTGTT
CGCTCAAGAGTTGCGCGCAGCGTTCAGGTCGTTGCGCTGA

Upstream 100 bases:

>100_bases
TGCCATCTACGCCGCCGCGGTGTATCAACCGAAACCCGACGTGCACCCGCCAACGACACGCCGCTGACCGGATTCCACTT
TCCCTCTACCTGGTATCGAC

Downstream 100 bases:

>100_bases
GCGCGGCAGGCGGGCGGCGGCGGGCGCTGAAGCATGGCAATGCCTTCAGCGCCCGAGCCGCCCTTGCTTCGTGCCCGCTT
ATCCGGGCGCATGGTCCGGG

Product: putative peptidase

Products: NA

Alternate protein names: Epoxide hydratase [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MKLHATRTAPAIATIALCLAQLALPSHAQASPAAEGGAIPQRAATEDASIRPFHASFPQAALADLRQRIAATRWPDRETV
SDQSQGVQLAKIQELVRYWGNDYDWFKAEQKLNAYPQFVTRIDGLDIHFLHVRSRHPNALPLVITHGWPGSVFELLKVIG
PLTDPTAYGGRAEDAFDVVIPSMPGYGFSGKPVGTGWGPDRIAGAWDVLMKRLGYTRYVSQGGDWGSVVAHAQGRQAPQG
LLGIHVNMPATVPADVARALKNGEAAPAGLSAAERSAFESMNKLYTLGGGYAAMMVTRPQTVGYGLADSPAGQAAWIYDK
FAAWTFSGGNPERSLTRDEMLDDITLYWLTNSATSSAQLYWENNTNNFNAAEQMTAQIKVPVGVTVFPGELYQAPRSWAE
RAYPRLTYFNKVDKGGHFAAWEEPQLFAQELRAAFRSLR

Sequences:

>Translated_439_residues
MKLHATRTAPAIATIALCLAQLALPSHAQASPAAEGGAIPQRAATEDASIRPFHASFPQAALADLRQRIAATRWPDRETV
SDQSQGVQLAKIQELVRYWGNDYDWFKAEQKLNAYPQFVTRIDGLDIHFLHVRSRHPNALPLVITHGWPGSVFELLKVIG
PLTDPTAYGGRAEDAFDVVIPSMPGYGFSGKPVGTGWGPDRIAGAWDVLMKRLGYTRYVSQGGDWGSVVAHAQGRQAPQG
LLGIHVNMPATVPADVARALKNGEAAPAGLSAAERSAFESMNKLYTLGGGYAAMMVTRPQTVGYGLADSPAGQAAWIYDK
FAAWTFSGGNPERSLTRDEMLDDITLYWLTNSATSSAQLYWENNTNNFNAAEQMTAQIKVPVGVTVFPGELYQAPRSWAE
RAYPRLTYFNKVDKGGHFAAWEEPQLFAQELRAAFRSLR
>Mature_439_residues
MKLHATRTAPAIATIALCLAQLALPSHAQASPAAEGGAIPQRAATEDASIRPFHASFPQAALADLRQRIAATRWPDRETV
SDQSQGVQLAKIQELVRYWGNDYDWFKAEQKLNAYPQFVTRIDGLDIHFLHVRSRHPNALPLVITHGWPGSVFELLKVIG
PLTDPTAYGGRAEDAFDVVIPSMPGYGFSGKPVGTGWGPDRIAGAWDVLMKRLGYTRYVSQGGDWGSVVAHAQGRQAPQG
LLGIHVNMPATVPADVARALKNGEAAPAGLSAAERSAFESMNKLYTLGGGYAAMMVTRPQTVGYGLADSPAGQAAWIYDK
FAAWTFSGGNPERSLTRDEMLDDITLYWLTNSATSSAQLYWENNTNNFNAAEQMTAQIKVPVGVTVFPGELYQAPRSWAE
RAYPRLTYFNKVDKGGHFAAWEEPQLFAQELRAAFRSLR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

Organism=Homo sapiens, GI4503583, Length=413, Percent_Identity=36.8038740920097, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI209862837, Length=413, Percent_Identity=36.8038740920097, Blast_Score=277, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17564944, Length=417, Percent_Identity=33.5731414868106, Blast_Score=235, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI193207462, Length=407, Percent_Identity=25.0614250614251, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI20130139, Length=396, Percent_Identity=33.3333333333333, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24655327, Length=402, Percent_Identity=30.8457711442786, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI19922580, Length=407, Percent_Identity=29.2383292383292, Blast_Score=177, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 47931; Mature: 47931

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHATRTAPAIATIALCLAQLALPSHAQASPAAEGGAIPQRAATEDASIRPFHASFPQA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
ALADLRQRIAATRWPDRETVSDQSQGVQLAKIQELVRYWGNDYDWFKAEQKLNAYPQFVT
HHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RIDGLDIHFLHVRSRHPNALPLVITHGWPGSVFELLKVIGPLTDPTAYGGRAEDAFDVVI
HCCCCEEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEE
PSMPGYGFSGKPVGTGWGPDRIAGAWDVLMKRLGYTRYVSQGGDWGSVVAHAQGRQAPQG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHCCCCCCCCC
LLGIHVNMPATVPADVARALKNGEAAPAGLSAAERSAFESMNKLYTLGGGYAAMMVTRPQ
EEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEECCCCEEEEEEECCH
TVGYGLADSPAGQAAWIYDKFAAWTFSGGNPERSLTRDEMLDDITLYWLTNSATSSAQLY
HCCCCCCCCCCCCEEEEEEHHEEEEECCCCCCCCCCHHHHHCCEEEEEEECCCCCCEEEE
WENNTNNFNAAEQMTAQIKVPVGVTVFPGELYQAPRSWAERAYPRLTYFNKVDKGGHFAA
ECCCCCCCCHHHHCEEEEEECEEEEECCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCC
WEEPQLFAQELRAAFRSLR
CCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLHATRTAPAIATIALCLAQLALPSHAQASPAAEGGAIPQRAATEDASIRPFHASFPQA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
ALADLRQRIAATRWPDRETVSDQSQGVQLAKIQELVRYWGNDYDWFKAEQKLNAYPQFVT
HHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RIDGLDIHFLHVRSRHPNALPLVITHGWPGSVFELLKVIGPLTDPTAYGGRAEDAFDVVI
HCCCCEEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEE
PSMPGYGFSGKPVGTGWGPDRIAGAWDVLMKRLGYTRYVSQGGDWGSVVAHAQGRQAPQG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHCCCCCCCCC
LLGIHVNMPATVPADVARALKNGEAAPAGLSAAERSAFESMNKLYTLGGGYAAMMVTRPQ
EEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHEECCCCEEEEEEECCH
TVGYGLADSPAGQAAWIYDKFAAWTFSGGNPERSLTRDEMLDDITLYWLTNSATSSAQLY
HCCCCCCCCCCCCEEEEEEHHEEEEECCCCCCCCCCHHHHHCCEEEEEEECCCCCCEEEE
WENNTNNFNAAEQMTAQIKVPVGVTVFPGELYQAPRSWAERAYPRLTYFNKVDKGGHFAA
ECCCCCCCCHHHHCEEEEEECEEEEECCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCC
WEEPQLFAQELRAAFRSLR
CCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226695 [H]