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The map label for this gene is cysW [H]

Identifier: 116695541

GI number: 116695541

Start: 1805762

End: 1806637

Strand: Direct

Name: cysW [H]

Synonym: H16_B1602

Alternate gene names: 116695541

Gene position: 1805762-1806637 (Clockwise)

Preceding gene: 116695540

Following gene: 116695542

Centisome position: 62.0

GC content: 65.64

Gene sequence:

>876_bases
ATGACCCCAACCCATCGCCGCCCCGGCTACTGGCTGCAACTGGCGCTCACACTGGCGGTCTGCGCCTTCATGACCGTGCC
GGTCGTGCTCTCCGTGCTGGCTGGCCTGACCAACAATATCTTCATCGGCCTGGAAAGCGGCCTGACCACGCGCTGGCTCG
CGGAAGTCTGGTCGCTCTATCGCAATACCATCTTCCTGTCGCTGCTGATCGCGCTGGCCTGCCTTGCCTGCACGCTGGTG
CTGGGCGTGCCGGCCGCGTACTACATGGCGCTGCGGCGCAACCGCATCACCCGGCTGATCGAGGAACTGCTGATGCTGCC
GGTGGCCGTTCCGGGCCTCGCGACCGCGCTTGGCCTGATCCTGCTCTACGGCACCTGGCAGGCGCTGCGCACGAGCTGGC
TGTTTATCCTGATCGGCCATGTGCTGTTCACCCTGCCCTTTATGGTGCGTTCGGTGCTGGCCATCCTTTCCGCCATCGAT
ATCCGCACGCTGGAGGACGCAGCGGCCAGCCTTGGCGCGAGCCGCCTGCAGCGCTTCCTTACCGTGGTGCTGCCCAATTG
CCGCCAGGGCATCCTGGCCGGCGCGCTCATGGTGGTCACGCTGTCGGTGGGCGAATTCAACCTCACCTGGATGCTGCACA
CGCCCACCACCCAGACGTTGCCGGTGGGCCTGGCCGACAGCTATGCCTCGATGCGGCTGGAGATCGGCTCGGCCTACACC
ATCGTCTTCTTCGTCATGATCATTCCGCTGCTGGTGCTGATGCAAGCGCTCAGCGCGCTGGGCGCGCGTTCCCGCAAGTA
TGTTCCCGAAGCGGTGCCCGCCCCTGCTGTTGCCGCCACGCCGGCCAACCCTCATACCGAGACCCGTCATGCATGA

Upstream 100 bases:

>100_bases
GCGCTGTCCATCCTGTTGGGCACCGTCACCTGGGCCTTGCTGGCGCTCGCGCGCTGGTTTTCCGGCGACGCCGTGGCCGC
GACCGCCTAGGAGCCATCCC

Downstream 100 bases:

>100_bases
ACCCACCACCATCAGGCTGCGCGATTGCGGCAAGACGTTTGCCGACGGCACGCTGGCGCTGCAGCCGCTGGATCTCGACA
TCGGCGCCGCGGAAACCGTG

Product: ABC-type transporter, permease component

Products: phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MTPTHRRPGYWLQLALTLAVCAFMTVPVVLSVLAGLTNNIFIGLESGLTTRWLAEVWSLYRNTIFLSLLIALACLACTLV
LGVPAAYYMALRRNRITRLIEELLMLPVAVPGLATALGLILLYGTWQALRTSWLFILIGHVLFTLPFMVRSVLAILSAID
IRTLEDAAASLGASRLQRFLTVVLPNCRQGILAGALMVVTLSVGEFNLTWMLHTPTTQTLPVGLADSYASMRLEIGSAYT
IVFFVMIIPLLVLMQALSALGARSRKYVPEAVPAPAVAATPANPHTETRHA

Sequences:

>Translated_291_residues
MTPTHRRPGYWLQLALTLAVCAFMTVPVVLSVLAGLTNNIFIGLESGLTTRWLAEVWSLYRNTIFLSLLIALACLACTLV
LGVPAAYYMALRRNRITRLIEELLMLPVAVPGLATALGLILLYGTWQALRTSWLFILIGHVLFTLPFMVRSVLAILSAID
IRTLEDAAASLGASRLQRFLTVVLPNCRQGILAGALMVVTLSVGEFNLTWMLHTPTTQTLPVGLADSYASMRLEIGSAYT
IVFFVMIIPLLVLMQALSALGARSRKYVPEAVPAPAVAATPANPHTETRHA
>Mature_290_residues
TPTHRRPGYWLQLALTLAVCAFMTVPVVLSVLAGLTNNIFIGLESGLTTRWLAEVWSLYRNTIFLSLLIALACLACTLVL
GVPAAYYMALRRNRITRLIEELLMLPVAVPGLATALGLILLYGTWQALRTSWLFILIGHVLFTLPFMVRSVLAILSAIDI
RTLEDAAASLGASRLQRFLTVVLPNCRQGILAGALMVVTLSVGEFNLTWMLHTPTTQTLPVGLADSYASMRLEIGSAYTI
VFFVMIIPLLVLMQALSALGARSRKYVPEAVPAPAVAATPANPHTETRHA

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787369, Length=165, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31697; Mature: 31566

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTHRRPGYWLQLALTLAVCAFMTVPVVLSVLAGLTNNIFIGLESGLTTRWLAEVWSLY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHH
RNTIFLSLLIALACLACTLVLGVPAAYYMALRRNRITRLIEELLMLPVAVPGLATALGLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LLYGTWQALRTSWLFILIGHVLFTLPFMVRSVLAILSAIDIRTLEDAAASLGASRLQRFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVVLPNCRQGILAGALMVVTLSVGEFNLTWMLHTPTTQTLPVGLADSYASMRLEIGSAYT
HHHCCHHHHHHHHHHHHHHHEECCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHH
IVFFVMIIPLLVLMQALSALGARSRKYVPEAVPAPAVAATPANPHTETRHA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCC
>Mature Secondary Structure 
TPTHRRPGYWLQLALTLAVCAFMTVPVVLSVLAGLTNNIFIGLESGLTTRWLAEVWSLY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHH
RNTIFLSLLIALACLACTLVLGVPAAYYMALRRNRITRLIEELLMLPVAVPGLATALGLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LLYGTWQALRTSWLFILIGHVLFTLPFMVRSVLAILSAIDIRTLEDAAASLGASRLQRFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVVLPNCRQGILAGALMVVTLSVGEFNLTWMLHTPTTQTLPVGLADSYASMRLEIGSAYT
HHHCCHHHHHHHHHHHHHHHEECCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHH
IVFFVMIIPLLVLMQALSALGARSRKYVPEAVPAPAVAATPANPHTETRHA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]