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The map label for this gene is cphA [H]

Identifier: 116695486

GI number: 116695486

Start: 1735000

End: 1735959

Strand: Direct

Name: cphA [H]

Synonym: H16_B1545

Alternate gene names: 116695486

Gene position: 1735000-1735959 (Clockwise)

Preceding gene: 116695483

Following gene: 116695487

Centisome position: 59.57

GC content: 66.98

Gene sequence:

>960_bases
ATGTCCAAGGCATTCGCATCGCAGGCCGACCTGGAAGCCAAGCAGGTCACCTTCACCCAACTGTCAGAGAACGCCTGGGC
CTACACCGCCGAAGGCGATCCCAATTCGGGCGTGGTCATCGGCGACGACGGCGTACTGATCGTCGACACCACCGCCACGC
CGGCCATGGCGCAGGACCTGATCGCCCGCATCCGCACCATCACCGACAAGCCCATCAAGTACGTGGTGCTGTCGCACTAC
CACGCGGTGCGCGTGCTGGGCGCGTCGGCCTACTTCGCGGAAGGCGCGCAGCAGGTCATCGCCAGCCGCGGCACCTACGA
GATGATCGTCGAGCGCGGCGAGGCCGACATGAAGTCCGAGATCGAGCGCTTCCCGCGCCTGTTCGCCGGCGTCGAGACCG
TGCCCGGCCTGACCTGGCCGACGCTGGTGTTCGAGAAGGAAATCACGCTGTTCCTGGGCAAGCTGGAAGTGCGCATCGCC
CACCTGGGCTCGGGCCATACCAAGGGCGACACCGTGGTCTGGCTGCCGCAGCAGAAGGTGCTGTTCTCCGGCGACCTGGT
CGAGTACGACGCCGCCTGCTACTGCGGCGACGCCCAGCTGGAAGACTGGCCGGCCACGCTGGACGCGCTGCAGGCACTCA
AGCCGGAAAAGCTGGTGCCCGGCCGCGGCCCCGCGCTGACCACGCCGGAGGAAGTGGACAAGGGTATCGCCTACACCAAG
GACTTCGTCACCACGCTGTTCCAGGCCGGCAAGGAAGCCGTGGCCGAGAAGCTCGACCTGAAGGCCGCGATGGCGCACAC
CCGGCGCGCGATGGACCCCAAGTTTGGCCAGGTCTTTATCTACGAGCACTGCCTGCCCTTCGACGTCTCGCGCGCCTATG
ACGAGGCCAGCGGCGTCCGCCACCCGCGCATCTGGACGGCCCAGCGCGACAAGGAAATGTGGGCCGCACTGCAGGACTGA

Upstream 100 bases:

>100_bases
CGTCAGGCATCCATAGAAACGGGGCGAGACAGCCCGCGGCCAGCGCAACGCAGCCATCGTGCCGGTGCCGTCTCGCCTCC
CCACACAAAGGAAAGACGCC

Downstream 100 bases:

>100_bases
CCTCCAAAAAGAATAAGTCGGGCAACAAGCTATGGATGGAGACACAGGCATGAGCAGCATCGATTACCAGCGGCTGTCGT
TCGAGTACCAGCCCTGCGCC

Product: Zn-dependent hydrolase or glyoxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSKAFASQADLEAKQVTFTQLSENAWAYTAEGDPNSGVVIGDDGVLIVDTTATPAMAQDLIARIRTITDKPIKYVVLSHY
HAVRVLGASAYFAEGAQQVIASRGTYEMIVERGEADMKSEIERFPRLFAGVETVPGLTWPTLVFEKEITLFLGKLEVRIA
HLGSGHTKGDTVVWLPQQKVLFSGDLVEYDAACYCGDAQLEDWPATLDALQALKPEKLVPGRGPALTTPEEVDKGIAYTK
DFVTTLFQAGKEAVAEKLDLKAAMAHTRRAMDPKFGQVFIYEHCLPFDVSRAYDEASGVRHPRIWTAQRDKEMWAALQD

Sequences:

>Translated_319_residues
MSKAFASQADLEAKQVTFTQLSENAWAYTAEGDPNSGVVIGDDGVLIVDTTATPAMAQDLIARIRTITDKPIKYVVLSHY
HAVRVLGASAYFAEGAQQVIASRGTYEMIVERGEADMKSEIERFPRLFAGVETVPGLTWPTLVFEKEITLFLGKLEVRIA
HLGSGHTKGDTVVWLPQQKVLFSGDLVEYDAACYCGDAQLEDWPATLDALQALKPEKLVPGRGPALTTPEEVDKGIAYTK
DFVTTLFQAGKEAVAEKLDLKAAMAHTRRAMDPKFGQVFIYEHCLPFDVSRAYDEASGVRHPRIWTAQRDKEMWAALQD
>Mature_318_residues
SKAFASQADLEAKQVTFTQLSENAWAYTAEGDPNSGVVIGDDGVLIVDTTATPAMAQDLIARIRTITDKPIKYVVLSHYH
AVRVLGASAYFAEGAQQVIASRGTYEMIVERGEADMKSEIERFPRLFAGVETVPGLTWPTLVFEKEITLFLGKLEVRIAH
LGSGHTKGDTVVWLPQQKVLFSGDLVEYDAACYCGDAQLEDWPATLDALQALKPEKLVPGRGPALTTPEEVDKGIAYTKD
FVTTLFQAGKEAVAEKLDLKAAMAHTRRAMDPKFGQVFIYEHCLPFDVSRAYDEASGVRHPRIWTAQRDKEMWAALQD

Specific function: Can hydrolyze carbapenem compounds [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001018
- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 35184; Mature: 35053

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKAFASQADLEAKQVTFTQLSENAWAYTAEGDPNSGVVIGDDGVLIVDTTATPAMAQDL
CCCCCCCCCCCCHHHHHHEECCCCCEEEEECCCCCCCEEECCCCEEEEECCCCHHHHHHH
IARIRTITDKPIKYVVLSHYHAVRVLGASAYFAEGAQQVIASRGTYEMIVERGEADMKSE
HHHHHHHCCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHH
IERFPRLFAGVETVPGLTWPTLVFEKEITLFLGKLEVRIAHLGSGHTKGDTVVWLPQQKV
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEEEEEEEEECCCCCCCCCEEEEECCCCE
LFSGDLVEYDAACYCGDAQLEDWPATLDALQALKPEKLVPGRGPALTTPEEVDKGIAYTK
EECCCEEEECCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCHHHHH
DFVTTLFQAGKEAVAEKLDLKAAMAHTRRAMDPKFGQVFIYEHCLPFDVSRAYDEASGVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCC
HPRIWTAQRDKEMWAALQD
CCCEECCCHHHHHHHHCCC
>Mature Secondary Structure 
SKAFASQADLEAKQVTFTQLSENAWAYTAEGDPNSGVVIGDDGVLIVDTTATPAMAQDL
CCCCCCCCCCCHHHHHHEECCCCCEEEEECCCCCCCEEECCCCEEEEECCCCHHHHHHH
IARIRTITDKPIKYVVLSHYHAVRVLGASAYFAEGAQQVIASRGTYEMIVERGEADMKSE
HHHHHHHCCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHH
IERFPRLFAGVETVPGLTWPTLVFEKEITLFLGKLEVRIAHLGSGHTKGDTVVWLPQQKV
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEEEEEEEEECCCCCCCCCEEEEECCCCE
LFSGDLVEYDAACYCGDAQLEDWPATLDALQALKPEKLVPGRGPALTTPEEVDKGIAYTK
EECCCEEEECCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCHHHHH
DFVTTLFQAGKEAVAEKLDLKAAMAHTRRAMDPKFGQVFIYEHCLPFDVSRAYDEASGVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCC
HPRIWTAQRDKEMWAALQD
CCCEECCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1856163 [H]