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The map label for this gene is cph2 [H]

Identifier: 116695463

GI number: 116695463

Start: 1709354

End: 1710970

Strand: Direct

Name: cph2 [H]

Synonym: H16_B1522

Alternate gene names: 116695463

Gene position: 1709354-1710970 (Clockwise)

Preceding gene: 116695461

Following gene: 116695466

Centisome position: 58.69

GC content: 66.98

Gene sequence:

>1617_bases
ATGCGCTGGCGCATAACGCAACTGAGCCAGGCTGCGGCCAGGTACTACAATGGCCGCATAAAAGCAGAACAGCTTTCCTT
CGTGCGTCAAATACCTCACTTTCCGGCCCGCAAAGCCATTTCCCGCCCGGCCTCCCTGATCGTTGCCGCCAGCCTTGTCC
TGGTCTGCATGATCGCGGCCCTTGGTGCCCTCGCCCTGGTGCAGATGCGCAGGGATGCACTGGACAATGCCAGCGAGGCC
TCGGCCAACCTGGCGCTGACGCTGGAACGCAGCATCACGCGCAACCTGCAGATCCATGAGCTGGCAATCGGGGGCATAGT
GGAAGCCATGCACGATCCCGCACTGCTGGCGCAACCGCCGGCGCTGCGCCAGCGGCTGCTGTTCGACCGCTTGATCAACG
CCGAAGACATGGGCTCGCTGCTGGTCACCGACGCCAACGGCACGCTGGTGTTCGACTCGCACCAGTGGCCGCCGCGCCCG
GTCAACGTTTCTGACCGCGACTACTTCCAGGTCCACCGCAGCGGCGATCACAGCGGCCTGTTCCTGAGCCGGCCGTTCCA
GCCGCGCCTGGCGCCGGAGAACAAGTCCATCGGCATCAGCCGGCGGCTTTCCGCACCGGACGGCAGCTTTGCCGGCACCG
TGGTCGGCACCTTGCGCCTGAACTACTTCCGCAAGCTGTTCGATGGCGTAAGCCTTGGCGCGGGCGGCACCCTGACGCTG
CTGCGCACGGACGGCACCATCATCATGCGGCGGCCCTATGAAGCCGAATCGATCGGGCGCGACATCTCCGGCAGCCCGTC
ATTTGCACCGCTGCTGCAAGGCACGCAAGGCACGTTTATCGGCGTCGCGGCAGTCGACGGGGTGCAGCGGCTCTACAGCT
TCAGGCGCACTCCGGGCTTTCCGCTGCTGGTCGTGGTGGGACGCGCCACCCACGACGTGCTGGCACCCTGGCACAAGCGC
GCCTGGGTGTTCGGGGCGATGATCATCGCGCTGGACGCTGCCATCATCGCGCTCTCGGTATTGCTGTCGCGCCAATGGCG
GCGCCGTGTCGAGATGGAAGAGCACCTGCGCTGGATGGTCAACACCGATGGCCTGACCGGCCTTGGCAGCCGCCGTGCGC
TGGACGATGCCGCCGACGTGGAATGGCGGCGCGCGCGCCGCCACAGCCAGCCTTTGTCGCTGCTGATGCTGGACGTCGAC
CACTTCAAGGAATTCAATGACCGCTACGGCCACCAGGCCGGTGACGATGCGCTGGCAGCGGTGGGCGCCTGCATCCAGCG
CCAGGTGCGGCGGCCGGGCGACTATGCGGGGCGCTATGGCGGCGAAGAGTTTGCCATCCTGCTGCCGCACACCAACGCTG
CCGGCGCGGCCGCCATGGCGGAGGCCATCCGCGCTGCCGTCCAGGCCTTGCAGATTCCGAATGCTGCCGGTGCCGACGGG
CACTTGACGGTCAGCATCGGTGCGGTGACCGATGCCAACGGCCCCGGCAACGAAAAGGATTTCGCCGAGCTGCGCGCCTT
TCTCCGTGCCGGCGACGAAGCGCTCTACCTGGCCAAGCGCTCCGGGCGCAATTGCGTCGCAACCTTCGGCGCCACGGCAG
CGGCGATGGCGTCCTGA

Upstream 100 bases:

>100_bases
TAGGGAAGAACTGTGCGTGCAGCGTAGTGCCGGACGCGCGCAGTGGCACACAGCACGTGTGCCCTGGCCAGGCAGGACCA
GGGCCGCAAGCTCCGGGACG

Downstream 100 bases:

>100_bases
GGGCCCGGCGCCGCGGCTACGCCAGTTCGAACCCATGCCGCGCCAGCGGCAGTGAACGGATGCGCTCGCCCGTGGCAGCA
AACAGCGCATTGGCCAGCGC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MRWRITQLSQAAARYYNGRIKAEQLSFVRQIPHFPARKAISRPASLIVAASLVLVCMIAALGALALVQMRRDALDNASEA
SANLALTLERSITRNLQIHELAIGGIVEAMHDPALLAQPPALRQRLLFDRLINAEDMGSLLVTDANGTLVFDSHQWPPRP
VNVSDRDYFQVHRSGDHSGLFLSRPFQPRLAPENKSIGISRRLSAPDGSFAGTVVGTLRLNYFRKLFDGVSLGAGGTLTL
LRTDGTIIMRRPYEAESIGRDISGSPSFAPLLQGTQGTFIGVAAVDGVQRLYSFRRTPGFPLLVVVGRATHDVLAPWHKR
AWVFGAMIIALDAAIIALSVLLSRQWRRRVEMEEHLRWMVNTDGLTGLGSRRALDDAADVEWRRARRHSQPLSLLMLDVD
HFKEFNDRYGHQAGDDALAAVGACIQRQVRRPGDYAGRYGGEEFAILLPHTNAAGAAAMAEAIRAAVQALQIPNAAGADG
HLTVSIGAVTDANGPGNEKDFAELRAFLRAGDEALYLAKRSGRNCVATFGATAAAMAS

Sequences:

>Translated_538_residues
MRWRITQLSQAAARYYNGRIKAEQLSFVRQIPHFPARKAISRPASLIVAASLVLVCMIAALGALALVQMRRDALDNASEA
SANLALTLERSITRNLQIHELAIGGIVEAMHDPALLAQPPALRQRLLFDRLINAEDMGSLLVTDANGTLVFDSHQWPPRP
VNVSDRDYFQVHRSGDHSGLFLSRPFQPRLAPENKSIGISRRLSAPDGSFAGTVVGTLRLNYFRKLFDGVSLGAGGTLTL
LRTDGTIIMRRPYEAESIGRDISGSPSFAPLLQGTQGTFIGVAAVDGVQRLYSFRRTPGFPLLVVVGRATHDVLAPWHKR
AWVFGAMIIALDAAIIALSVLLSRQWRRRVEMEEHLRWMVNTDGLTGLGSRRALDDAADVEWRRARRHSQPLSLLMLDVD
HFKEFNDRYGHQAGDDALAAVGACIQRQVRRPGDYAGRYGGEEFAILLPHTNAAGAAAMAEAIRAAVQALQIPNAAGADG
HLTVSIGAVTDANGPGNEKDFAELRAFLRAGDEALYLAKRSGRNCVATFGATAAAMAS
>Mature_538_residues
MRWRITQLSQAAARYYNGRIKAEQLSFVRQIPHFPARKAISRPASLIVAASLVLVCMIAALGALALVQMRRDALDNASEA
SANLALTLERSITRNLQIHELAIGGIVEAMHDPALLAQPPALRQRLLFDRLINAEDMGSLLVTDANGTLVFDSHQWPPRP
VNVSDRDYFQVHRSGDHSGLFLSRPFQPRLAPENKSIGISRRLSAPDGSFAGTVVGTLRLNYFRKLFDGVSLGAGGTLTL
LRTDGTIIMRRPYEAESIGRDISGSPSFAPLLQGTQGTFIGVAAVDGVQRLYSFRRTPGFPLLVVVGRATHDVLAPWHKR
AWVFGAMIIALDAAIIALSVLLSRQWRRRVEMEEHLRWMVNTDGLTGLGSRRALDDAADVEWRRARRHSQPLSLLMLDVD
HFKEFNDRYGHQAGDDALAAVGACIQRQVRRPGDYAGRYGGEEFAILLPHTNAAGAAAMAEAIRAAVQALQIPNAAGADG
HLTVSIGAVTDANGPGNEKDFAELRAFLRAGDEALYLAKRSGRNCVATFGATAAAMAS

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=181, Percent_Identity=39.7790055248619, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI87082007, Length=210, Percent_Identity=35.7142857142857, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786584, Length=174, Percent_Identity=34.4827586206897, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI87081881, Length=202, Percent_Identity=34.6534653465347, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787262, Length=167, Percent_Identity=35.3293413173653, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1787802, Length=167, Percent_Identity=37.125748502994, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1787816, Length=171, Percent_Identity=36.2573099415205, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788085, Length=165, Percent_Identity=30.3030303030303, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787541, Length=183, Percent_Identity=32.7868852459016, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87081974, Length=160, Percent_Identity=27.5, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081977, Length=161, Percent_Identity=29.8136645962733, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1788381, Length=205, Percent_Identity=28.2926829268293, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 58501; Mature: 58501

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWRITQLSQAAARYYNGRIKAEQLSFVRQIPHFPARKAISRPASLIVAASLVLVCMIAA
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
LGALALVQMRRDALDNASEASANLALTLERSITRNLQIHELAIGGIVEAMHDPALLAQPP
HHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHCCCEEEEHHHHHHHHHHCCCHHHCCCH
ALRQRLLFDRLINAEDMGSLLVTDANGTLVFDSHQWPPRPVNVSDRDYFQVHRSGDHSGL
HHHHHHHHHHHCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCE
FLSRPFQPRLAPENKSIGISRRLSAPDGSFAGTVVGTLRLNYFRKLFDGVSLGAGGTLTL
EEECCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
LRTDGTIIMRRPYEAESIGRDISGSPSFAPLLQGTQGTFIGVAAVDGVQRLYSFRRTPGF
EEECCEEEEECCCCHHHHCCCCCCCCCHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCC
PLLVVVGRATHDVLAPWHKRAWVFGAMIIALDAAIIALSVLLSRQWRRRVEMEEHLRWMV
EEEEEECCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEE
NTDGLTGLGSRRALDDAADVEWRRARRHSQPLSLLMLDVDHFKEFNDRYGHQAGDDALAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCCHHHHHH
VGACIQRQVRRPGDYAGRYGGEEFAILLPHTNAAGAAAMAEAIRAAVQALQIPNAAGADG
HHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
HLTVSIGAVTDANGPGNEKDFAELRAFLRAGDEALYLAKRSGRNCVATFGATAAAMAS
EEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCHHHHHCC
>Mature Secondary Structure
MRWRITQLSQAAARYYNGRIKAEQLSFVRQIPHFPARKAISRPASLIVAASLVLVCMIAA
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
LGALALVQMRRDALDNASEASANLALTLERSITRNLQIHELAIGGIVEAMHDPALLAQPP
HHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHCCCEEEEHHHHHHHHHHCCCHHHCCCH
ALRQRLLFDRLINAEDMGSLLVTDANGTLVFDSHQWPPRPVNVSDRDYFQVHRSGDHSGL
HHHHHHHHHHHCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCE
FLSRPFQPRLAPENKSIGISRRLSAPDGSFAGTVVGTLRLNYFRKLFDGVSLGAGGTLTL
EEECCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
LRTDGTIIMRRPYEAESIGRDISGSPSFAPLLQGTQGTFIGVAAVDGVQRLYSFRRTPGF
EEECCEEEEECCCCHHHHCCCCCCCCCHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCC
PLLVVVGRATHDVLAPWHKRAWVFGAMIIALDAAIIALSVLLSRQWRRRVEMEEHLRWMV
EEEEEECCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEE
NTDGLTGLGSRRALDDAADVEWRRARRHSQPLSLLMLDVDHFKEFNDRYGHQAGDDALAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCCHHHHHH
VGACIQRQVRRPGDYAGRYGGEEFAILLPHTNAAGAAAMAEAIRAAVQALQIPNAAGADG
HHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
HLTVSIGAVTDANGPGNEKDFAELRAFLRAGDEALYLAKRSGRNCVATFGATAAAMAS
EEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]