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The map label for this gene is crp [C]

Identifier: 116695343

GI number: 116695343

Start: 1569084

End: 1569770

Strand: Direct

Name: crp [C]

Synonym: H16_B1400

Alternate gene names: 116695343

Gene position: 1569084-1569770 (Clockwise)

Preceding gene: 116695339

Following gene: 116695345

Centisome position: 53.87

GC content: 58.22

Gene sequence:

>687_bases
ATGGATCTCAACGCGCCCCTCATTGAGAAAATGTCCGGAAACCCGTGGTTTCAATCGCTGCCCATGGCCGAGCGACAAAA
CCTGGTGGGAAACAGTACCCAGGTACGACTCGCCGTTGGCGAGTCATTGTTCCGGCGCGGCGATCCGCCGGCCGGCTTCT
TCGGTATCGTTGACGGACGCTTGAAGGCGTCAAGCGTCCGCAGTGACGGCAAGGAAGGCATCCTCGTCATCCTCGAGCAA
GGCAACTGGTTCGGACAAATGTCCACCATTACCGGGTGGCCAAGCGCTTTTGACGTTACCGCGGTCGAGGCCGCTCTTGT
CCTGAAGCTCAGCCCTGAAGCGTTCAATGCATTTATGCAGAACGCCGTGTTTGCGAGAGCCATCGCCGTACTGCTGTGCC
AGCACACGAGCCTGCTCTATCAGATGCTCGAAGACGCGACGCTCCATTCCACTCGTACAAGGATCGCCCGTCGTTTGATG
CGTCTTGCTCGTGGTGACGCAACTCTGGCTGCCGAGCATCGGGCGAAAATCCCTGTTTCCCAGGATACGCTCGCCATGAT
GCTTGGCATTTCGCGCCAGACACTTGCTCTTGAACTCAAGGCGATGGCTGCGCAAGGTGCCGTTGCCTTGCGCTACGGGC
ACGTCGAGATCGTTTCCATGGACGTTCTCATGTCGTTCGACGACTAG

Upstream 100 bases:

>100_bases
TGCGGTGCAGCGTGCTCGCATGCTACGAGCGGACCGTCTCGCCAGTCTGTAAGATGTCTTGCAATTGCAGGATTCATTAA
GCGCTTTCGACTGCCCCACC

Downstream 100 bases:

>100_bases
GGGCGGTCGAAGGCAAAGCGCGATCCACGCCATGAAGCCGCGACATGACTACGCCGGCTGAGACCAGCAGCGCCGCAAGG
ACATACAATCCAATTGAAGT

Product: Crp family transcriptional regulator

Products: NA

Alternate protein names: Transcriptional Regulator Crp/Fnr Family; Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Regulatory Protein; Crp/Fnr Family Transcriptional Regulator; CAMP-Dependent Transcriptional Regulator; Transcription Regulator Protein; Transcriptional Regulator Anr; Transcription Regulator Crp Family; CNMP Regulatory Protein; Cyclic-Nucleotide-Gated Cation Channel; GntR Family Transcriptional Regulator; Transcriptional Regulator Crp; Catabolite Gene Activator; Transcriptional Regulator Crp Family

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MDLNAPLIEKMSGNPWFQSLPMAERQNLVGNSTQVRLAVGESLFRRGDPPAGFFGIVDGRLKASSVRSDGKEGILVILEQ
GNWFGQMSTITGWPSAFDVTAVEAALVLKLSPEAFNAFMQNAVFARAIAVLLCQHTSLLYQMLEDATLHSTRTRIARRLM
RLARGDATLAAEHRAKIPVSQDTLAMMLGISRQTLALELKAMAAQGAVALRYGHVEIVSMDVLMSFDD

Sequences:

>Translated_228_residues
MDLNAPLIEKMSGNPWFQSLPMAERQNLVGNSTQVRLAVGESLFRRGDPPAGFFGIVDGRLKASSVRSDGKEGILVILEQ
GNWFGQMSTITGWPSAFDVTAVEAALVLKLSPEAFNAFMQNAVFARAIAVLLCQHTSLLYQMLEDATLHSTRTRIARRLM
RLARGDATLAAEHRAKIPVSQDTLAMMLGISRQTLALELKAMAAQGAVALRYGHVEIVSMDVLMSFDD
>Mature_228_residues
MDLNAPLIEKMSGNPWFQSLPMAERQNLVGNSTQVRLAVGESLFRRGDPPAGFFGIVDGRLKASSVRSDGKEGILVILEQ
GNWFGQMSTITGWPSAFDVTAVEAALVLKLSPEAFNAFMQNAVFARAIAVLLCQHTSLLYQMLEDATLHSTRTRIARRLM
RLARGDATLAAEHRAKIPVSQDTLAMMLGISRQTLALELKAMAAQGAVALRYGHVEIVSMDVLMSFDD

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 24906; Mature: 24906

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNAPLIEKMSGNPWFQSLPMAERQNLVGNSTQVRLAVGESLFRRGDPPAGFFGIVDGR
CCCCCCHHHHCCCCCCHHCCCHHHHHHHCCCCCEEEEEECHHHHHCCCCCCCEEEEECCC
LKASSVRSDGKEGILVILEQGNWFGQMSTITGWPSAFDVTAVEAALVLKLSPEAFNAFMQ
EEHHHHCCCCCCCEEEEEECCCCEEECCCCCCCCCCCHHHHHHEEEEEEECHHHHHHHHH
NAVFARAIAVLLCQHTSLLYQMLEDATLHSTRTRIARRLMRLARGDATLAAEHRAKIPVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCC
QDTLAMMLGISRQTLALELKAMAAQGAVALRYGHVEIVSMDVLMSFDD
HHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCEEEEEEEEEEECCC
>Mature Secondary Structure
MDLNAPLIEKMSGNPWFQSLPMAERQNLVGNSTQVRLAVGESLFRRGDPPAGFFGIVDGR
CCCCCCHHHHCCCCCCHHCCCHHHHHHHCCCCCEEEEEECHHHHHCCCCCCCEEEEECCC
LKASSVRSDGKEGILVILEQGNWFGQMSTITGWPSAFDVTAVEAALVLKLSPEAFNAFMQ
EEHHHHCCCCCCCEEEEEECCCCEEECCCCCCCCCCCHHHHHHEEEEEEECHHHHHHHHH
NAVFARAIAVLLCQHTSLLYQMLEDATLHSTRTRIARRLMRLARGDATLAAEHRAKIPVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCC
QDTLAMMLGISRQTLALELKAMAAQGAVALRYGHVEIVSMDVLMSFDD
HHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA