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The map label for this gene is cat2 [H]

Identifier: 116695311

GI number: 116695311

Start: 1529761

End: 1531071

Strand: Direct

Name: cat2 [H]

Synonym: H16_B1368

Alternate gene names: 116695311

Gene position: 1529761-1531071 (Clockwise)

Preceding gene: 116695309

Following gene: 116695312

Centisome position: 52.52

GC content: 71.7

Gene sequence:

>1311_bases
GTGGACATGCACACCCTCGCCTCCCGCCTGCAAGCCCTGATCCGCCCCGGAGACCATATCTGGTGGGGGCAAGCCACCGC
CGAGCCGCTGACGCTGACGCGCGCACTGGTGGAGCACCGCCACGCCATCGCCCAGGGCGGACGGCTCAGTGTCTTTGTCG
GCATCGGGCAGTCAGACACGCTGCAGCCGGCCCAGGCGGATGTGCTCGACTTCTTCGGCTACGCCGCCAGCGGCCCGCAC
CGGCAACTGGCCAGGGCCGGCGTGCTGGACATCGTGCCCAGCCACTATTCGCACCTGCCCGGGCTGATCCGCCAGGGCAC
GCTGCGGGCGGACGTGGCGCTGGTGCAGGTCTCGCCCGCCGACGAGCAGGGGCGCCACAGCCTGGGGCTGGTGCATGAAT
ACCTCCCCGCGGCGCTCGACCGCGCCCGCGTCATCATCGCCGAGGTGAACCCTGAGGTGCCTTGGACCCACGGCAGCCGC
TACCTGAGCGCGGACGATATCGACCTGCAGATCGAAGCGCTGCACCCGCCGATCAGCCTTGACCGCAGCGCGCCCGGCGC
GGCCGAACAGGCCATCGCCCGTCACATCGCCGGCTGGGTGGAGGATGGCGCCACCCTGCAGATGGGCATCGGCAACCTGC
CAGAGGCCGTGGTCGCTGCGCTGAATGGCCACCGCGACCTGGGGCTGCACAGCGGCGCGATCGGCGACGGCATTGCGGCG
CTGGCCGAAGCCGGGGTGCTGACCAACGCACGCAAGAGCATCGATACGGGCGTGGGCATCGCCGGCATCCTGATGGGCAG
CGAACGGCTGCGGCGCTGGGCCCACCGCAATCCGCAGCTGCAGCTGCGCGAGACCGCCTATACCCATCACCCCGAGGTGC
TGGCCAGCGTCGACAAGCTGACCGCCATCAACTCCGCCATCGAGGTCGACCTCACCGGCCAGGTGAACGCCGAAGTTGCC
GCCGGCGTCTATGTCGGCGCCGTCGGCGGTGCCGTGGACTTCCTGCGCGGCGCCGCGCGCAGCCGCGGCGGCCTGCCCAT
AGTCGCGCTGCCAGCAACCGCCAAGGGCGCGAGCCGCATCGTGGCCCAGTTGTCCGGCCCGGTCAGCACGCCCCGCTCGG
ACGCGGGCCTGATCGTCACCGAACACGGCGTGGCCGACCTGCGCGGCCAGACGCTGTCGCAGCGCGTGCGCCGCATGCTG
GACATTGCCGCACCCGAACACCGCGCGGACCTGGAACGCCAGGCCCACGCCCTGCTGCGTCAGTGCGGCGCGGCCTTCGT
GGCCCTTCCCGGGCACACGCTGGCCAACTGA

Upstream 100 bases:

>100_bases
TTTCGCCAAAGTCCGCCATTGGCATTGTCAAATAGCGCAAACCACGCTTTGGGAACATGCTCCGGGCTATCCGGCGCATG
CGCCGACTGACCGCTGCCCC

Downstream 100 bases:

>100_bases
CTTACTTGCTCATCCCAACACAGAGTTCCAAGGAGACTTCCATGCGCAGAGCTGCAATCGTCACTCCCCTCCGCACGCCC
GTCGGCACCTTCGGCGGCAG

Product: Acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MDMHTLASRLQALIRPGDHIWWGQATAEPLTLTRALVEHRHAIAQGGRLSVFVGIGQSDTLQPAQADVLDFFGYAASGPH
RQLARAGVLDIVPSHYSHLPGLIRQGTLRADVALVQVSPADEQGRHSLGLVHEYLPAALDRARVIIAEVNPEVPWTHGSR
YLSADDIDLQIEALHPPISLDRSAPGAAEQAIARHIAGWVEDGATLQMGIGNLPEAVVAALNGHRDLGLHSGAIGDGIAA
LAEAGVLTNARKSIDTGVGIAGILMGSERLRRWAHRNPQLQLRETAYTHHPEVLASVDKLTAINSAIEVDLTGQVNAEVA
AGVYVGAVGGAVDFLRGAARSRGGLPIVALPATAKGASRIVAQLSGPVSTPRSDAGLIVTEHGVADLRGQTLSQRVRRML
DIAAPEHRADLERQAHALLRQCGAAFVALPGHTLAN

Sequences:

>Translated_436_residues
MDMHTLASRLQALIRPGDHIWWGQATAEPLTLTRALVEHRHAIAQGGRLSVFVGIGQSDTLQPAQADVLDFFGYAASGPH
RQLARAGVLDIVPSHYSHLPGLIRQGTLRADVALVQVSPADEQGRHSLGLVHEYLPAALDRARVIIAEVNPEVPWTHGSR
YLSADDIDLQIEALHPPISLDRSAPGAAEQAIARHIAGWVEDGATLQMGIGNLPEAVVAALNGHRDLGLHSGAIGDGIAA
LAEAGVLTNARKSIDTGVGIAGILMGSERLRRWAHRNPQLQLRETAYTHHPEVLASVDKLTAINSAIEVDLTGQVNAEVA
AGVYVGAVGGAVDFLRGAARSRGGLPIVALPATAKGASRIVAQLSGPVSTPRSDAGLIVTEHGVADLRGQTLSQRVRRML
DIAAPEHRADLERQAHALLRQCGAAFVALPGHTLAN
>Mature_436_residues
MDMHTLASRLQALIRPGDHIWWGQATAEPLTLTRALVEHRHAIAQGGRLSVFVGIGQSDTLQPAQADVLDFFGYAASGPH
RQLARAGVLDIVPSHYSHLPGLIRQGTLRADVALVQVSPADEQGRHSLGLVHEYLPAALDRARVIIAEVNPEVPWTHGSR
YLSADDIDLQIEALHPPISLDRSAPGAAEQAIARHIAGWVEDGATLQMGIGNLPEAVVAALNGHRDLGLHSGAIGDGIAA
LAEAGVLTNARKSIDTGVGIAGILMGSERLRRWAHRNPQLQLRETAYTHHPEVLASVDKLTAINSAIEVDLTGQVNAEVA
AGVYVGAVGGAVDFLRGAARSRGGLPIVALPATAKGASRIVAQLSGPVSTPRSDAGLIVTEHGVADLRGQTLSQRVRRML
DIAAPEHRADLERQAHALLRQCGAAFVALPGHTLAN

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=388, Percent_Identity=25.7731958762887, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32563853, Length=348, Percent_Identity=35.9195402298851, Blast_Score=205, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI17538151, Length=415, Percent_Identity=32.289156626506, Blast_Score=202, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6319456, Length=467, Percent_Identity=24.1970021413276, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358615, Length=420, Percent_Identity=34.0476190476191, Blast_Score=240, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 46008; Mature: 46008

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMHTLASRLQALIRPGDHIWWGQATAEPLTLTRALVEHRHAIAQGGRLSVFVGIGQSDT
CCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
LQPAQADVLDFFGYAASGPHRQLARAGVLDIVPSHYSHLPGLIRQGTLRADVALVQVSPA
CCCHHHHHHHHHHCCCCCHHHHHHHCCHHHHCCCHHHHCCHHHHCCCCEEEEEEEEECCC
DEQGRHSLGLVHEYLPAALDRARVIIAEVNPEVPWTHGSRYLSADDIDLQIEALHPPISL
CCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEECCCCCEEEEEEECCCCCC
DRSAPGAAEQAIARHIAGWVEDGATLQMGIGNLPEAVVAALNGHRDLGLHSGAIGDGIAA
CCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHH
LAEAGVLTNARKSIDTGVGIAGILMGSERLRRWAHRNPQLQLRETAYTHHPEVLASVDKL
HHHHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHCCCCCEEEEHHHHCCCHHHHHHHHHH
TAINSAIEVDLTGQVNAEVAAGVYVGAVGGAVDFLRGAARSRGGLPIVALPATAKGASRI
HHHCCEEEEEECCCCCCHHHCCEEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHH
VAQLSGPVSTPRSDAGLIVTEHGVADLRGQTLSQRVRRMLDIAAPEHRADLERQAHALLR
HHHHCCCCCCCCCCCCEEEEECCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
QCGAAFVALPGHTLAN
HCCCEEEEECCHHCCC
>Mature Secondary Structure
MDMHTLASRLQALIRPGDHIWWGQATAEPLTLTRALVEHRHAIAQGGRLSVFVGIGQSDT
CCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
LQPAQADVLDFFGYAASGPHRQLARAGVLDIVPSHYSHLPGLIRQGTLRADVALVQVSPA
CCCHHHHHHHHHHCCCCCHHHHHHHCCHHHHCCCHHHHCCHHHHCCCCEEEEEEEEECCC
DEQGRHSLGLVHEYLPAALDRARVIIAEVNPEVPWTHGSRYLSADDIDLQIEALHPPISL
CCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEECCCCCEEEEEEECCCCCC
DRSAPGAAEQAIARHIAGWVEDGATLQMGIGNLPEAVVAALNGHRDLGLHSGAIGDGIAA
CCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHH
LAEAGVLTNARKSIDTGVGIAGILMGSERLRRWAHRNPQLQLRETAYTHHPEVLASVDKL
HHHHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHCCCCCEEEEHHHHCCCHHHHHHHHHH
TAINSAIEVDLTGQVNAEVAAGVYVGAVGGAVDFLRGAARSRGGLPIVALPATAKGASRI
HHHCCEEEEEECCCCCCHHHCCEEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHH
VAQLSGPVSTPRSDAGLIVTEHGVADLRGQTLSQRVRRMLDIAAPEHRADLERQAHALLR
HHHHCCCCCCCCCCCCEEEEECCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
QCGAAFVALPGHTLAN
HCCCEEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]