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The map label for this gene is glcD [H]

Identifier: 116695126

GI number: 116695126

Start: 1335192

End: 1336637

Strand: Direct

Name: glcD [H]

Synonym: H16_B1181

Alternate gene names: 116695126

Gene position: 1335192-1336637 (Clockwise)

Preceding gene: 116695125

Following gene: 116695127

Centisome position: 45.84

GC content: 67.08

Gene sequence:

>1446_bases
ATGCCAGCCGAAACCCCGACCCCAGACACCACCTTGCGCGCGATGCAGGCCATCGTTGGTGCAAGCGCCTGCCGCAGCGG
CGACGCCGACACGCAGGCCTACGTCACCGACTACCGCGGCATCTACCGCGGCCAGGCCCAGGTAGTGGTGCTGCCGTCAT
CGACGGAAGAGGTCAGCCAGGTGCTGCAGTGGTGCCATGCCCGGCGTGTGCCGGTGGTGCCGCAGGGCGGCAATACCTCG
CTGATGGGCGGCGCCGTGCCGGACGACAGCGGCACCGCCGTGGTCGTCAACCTCAGCCGCATGAACCGCGTGCTGGACCT
CGACACCATCAACGACACCATGACCGTGCAGTCCGGCGTCACGCTGAGCGCGGCGCGCAGCGCCGCCGAGGCCTGGCAAC
GCCTGTTCCCGCTGCGCATCGGCTCCGAAGGCTCATGCCAGATCGGCGGCAACCTGTCGACCAATGCCGGCGGCACCGCG
GTGCTGCGCTACGGCAATATGCGCGACCTCGTGCTCGGCATCGAGGTGGTGCTGCCCGATGGCCGCATCTACTCATCGCT
GCGCGGCCTGCGCAAGGACAACACCGGCTACGACCTCAAGCAGCTGTTCGTCGGCGCGGAAGGTACGCTCGGCATCATCA
CCGGCGCCGTGCTCAAGCTGATGCCGCAGCCGCGCAGCAGCGCCGTGGCCTTTGTCGCCGTACAGGACCCCGCCGCGGCC
GTGGCCTTGCTGGGTGAAGCCAAGCGCCTGTCCGGCCAGGCCGTGACCGCGTTCGAGCTGATCTCGCGGCCCGCGCTGGA
ACTGGTGCTTGAATATCTTGGCAACGTGGCTTCGCCGCTGCAGGACAAGCACGAGTGGATGGTGCTGATCGAACTCACCT
CCGGGACCGATGCGGAAAGCCTCAACGCCACGCTGATGGAAATCCTCGAATCCGGCTTCAGCCAGGGCCTGGTGCAGGAC
GCCGCAGTGGCCGCCAGCCTGTCCGACGCCCAGACTTTCTGGCGCATCCGCGAAGAGATCTCCGACGCCCAGACCCGCAC
CGGCGGCAGCATCAAGTGCGATGTCTCGGTGCCGCTGTCGCGCATCGCTACGTTTGTGGAGGAAGCCTCGGCCAGGGTGC
TGGAGCTGGTGCCGGACGCGCGCATGGTGATCTACGGCCATATGGGCGACGGCAATGTGCACTTCAACCCGCTGCGACCC
AGGGATCAGCCAGGAAAAGAGTTCCTGGCGCAGTGGTATGAGCGGGTCTCGGCACTGGTCGACGGCATGGCCCATGCGGA
AAACGGCTCGATCTCGGCCGAGCACGGCATCGGCGTGGCCAAGCGCGACGACCTGACGCGCTACAAGTCCCAGGTGGAAC
TGGAGCTGATGTGGCAGGTGAAGCAGGCGCTTGATCCGTTGAACCTGCTGAATCCGGGCAAGGTGCTGCCGACGCCGGCC
CGATAG

Upstream 100 bases:

>100_bases
CGCAAGCTTGCCGCATCGTTCCGCGAGCAGCCCTCTGACGCTCCCGCCGCAGACAAGCCTTCCGCCGCGTACTGACCCGT
ATCTCCTTCGCCTTACACCC

Downstream 100 bases:

>100_bases
CTCACCGCTATTCCACACCACGGAACGCGGGCAGGGCGCGCGTAGCAGGAATCGCCCATCTGGGCTAAGGTGTCAGCTAT
CCAGAACGCGCGGAGCCGGG

Product: FAD-dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MPAETPTPDTTLRAMQAIVGASACRSGDADTQAYVTDYRGIYRGQAQVVVLPSSTEEVSQVLQWCHARRVPVVPQGGNTS
LMGGAVPDDSGTAVVVNLSRMNRVLDLDTINDTMTVQSGVTLSAARSAAEAWQRLFPLRIGSEGSCQIGGNLSTNAGGTA
VLRYGNMRDLVLGIEVVLPDGRIYSSLRGLRKDNTGYDLKQLFVGAEGTLGIITGAVLKLMPQPRSSAVAFVAVQDPAAA
VALLGEAKRLSGQAVTAFELISRPALELVLEYLGNVASPLQDKHEWMVLIELTSGTDAESLNATLMEILESGFSQGLVQD
AAVAASLSDAQTFWRIREEISDAQTRTGGSIKCDVSVPLSRIATFVEEASARVLELVPDARMVIYGHMGDGNVHFNPLRP
RDQPGKEFLAQWYERVSALVDGMAHAENGSISAEHGIGVAKRDDLTRYKSQVELELMWQVKQALDPLNLLNPGKVLPTPA
R

Sequences:

>Translated_481_residues
MPAETPTPDTTLRAMQAIVGASACRSGDADTQAYVTDYRGIYRGQAQVVVLPSSTEEVSQVLQWCHARRVPVVPQGGNTS
LMGGAVPDDSGTAVVVNLSRMNRVLDLDTINDTMTVQSGVTLSAARSAAEAWQRLFPLRIGSEGSCQIGGNLSTNAGGTA
VLRYGNMRDLVLGIEVVLPDGRIYSSLRGLRKDNTGYDLKQLFVGAEGTLGIITGAVLKLMPQPRSSAVAFVAVQDPAAA
VALLGEAKRLSGQAVTAFELISRPALELVLEYLGNVASPLQDKHEWMVLIELTSGTDAESLNATLMEILESGFSQGLVQD
AAVAASLSDAQTFWRIREEISDAQTRTGGSIKCDVSVPLSRIATFVEEASARVLELVPDARMVIYGHMGDGNVHFNPLRP
RDQPGKEFLAQWYERVSALVDGMAHAENGSISAEHGIGVAKRDDLTRYKSQVELELMWQVKQALDPLNLLNPGKVLPTPA
R
>Mature_480_residues
PAETPTPDTTLRAMQAIVGASACRSGDADTQAYVTDYRGIYRGQAQVVVLPSSTEEVSQVLQWCHARRVPVVPQGGNTSL
MGGAVPDDSGTAVVVNLSRMNRVLDLDTINDTMTVQSGVTLSAARSAAEAWQRLFPLRIGSEGSCQIGGNLSTNAGGTAV
LRYGNMRDLVLGIEVVLPDGRIYSSLRGLRKDNTGYDLKQLFVGAEGTLGIITGAVLKLMPQPRSSAVAFVAVQDPAAAV
ALLGEAKRLSGQAVTAFELISRPALELVLEYLGNVASPLQDKHEWMVLIELTSGTDAESLNATLMEILESGFSQGLVQDA
AVAASLSDAQTFWRIREEISDAQTRTGGSIKCDVSVPLSRIATFVEEASARVLELVPDARMVIYGHMGDGNVHFNPLRPR
DQPGKEFLAQWYERVSALVDGMAHAENGSISAEHGIGVAKRDDLTRYKSQVELELMWQVKQALDPLNLLNPGKVLPTPAR

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=452, Percent_Identity=40.929203539823, Blast_Score=315, Evalue=5e-86,
Organism=Homo sapiens, GI37595756, Length=489, Percent_Identity=32.9243353783231, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI37595754, Length=512, Percent_Identity=31.8359375, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI4501993, Length=220, Percent_Identity=30.4545454545455, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI1789351, Length=463, Percent_Identity=31.317494600432, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1787977, Length=533, Percent_Identity=24.390243902439, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI48994907, Length=237, Percent_Identity=27.4261603375527, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534361, Length=477, Percent_Identity=33.3333333333333, Blast_Score=252, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI71992373, Length=480, Percent_Identity=30.625, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71992381, Length=481, Percent_Identity=29.7297297297297, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71992392, Length=373, Percent_Identity=31.3672922252011, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17556096, Length=179, Percent_Identity=27.3743016759777, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320023, Length=470, Percent_Identity=37.2340425531915, Blast_Score=320, Evalue=4e-88,
Organism=Saccharomyces cerevisiae, GI6320764, Length=451, Percent_Identity=35.920177383592, Blast_Score=308, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6320027, Length=480, Percent_Identity=29.5833333333333, Blast_Score=195, Evalue=2e-50,
Organism=Drosophila melanogaster, GI18921117, Length=448, Percent_Identity=36.8303571428571, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24639277, Length=448, Percent_Identity=36.8303571428571, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24639275, Length=448, Percent_Identity=36.8303571428571, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24653753, Length=478, Percent_Identity=24.2677824267782, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 51551; Mature: 51420

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAETPTPDTTLRAMQAIVGASACRSGDADTQAYVTDYRGIYRGQAQVVVLPSSTEEVSQ
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHH
VLQWCHARRVPVVPQGGNTSLMGGAVPDDSGTAVVVNLSRMNRVLDLDTINDTMTVQSGV
HHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCEEEEEHHHHCCEEEEECCCCCEEECCCC
TLSAARSAAEAWQRLFPLRIGSEGSCQIGGNLSTNAGGTAVLRYGNMRDLVLGIEVVLPD
CHHHHHHHHHHHHHHCCEEECCCCCEEECCCCCCCCCCEEEEEECCCEEEEEEEEEEECC
GRIYSSLRGLRKDNTGYDLKQLFVGAEGTLGIITGAVLKLMPQPRSSAVAFVAVQDPAAA
CHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCHHH
VALLGEAKRLSGQAVTAFELISRPALELVLEYLGNVASPLQDKHEWMVLIELTSGTDAES
HHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHH
LNATLMEILESGFSQGLVQDAAVAASLSDAQTFWRIREEISDAQTRTGGSIKCDVSVPLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHH
RIATFVEEASARVLELVPDARMVIYGHMGDGNVHFNPLRPRDQPGKEFLAQWYERVSALV
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHH
DGMAHAENGSISAEHGIGVAKRDDLTRYKSQVELELMWQVKQALDPLNLLNPGKVLPTPA
HHHHHCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
R
C
>Mature Secondary Structure 
PAETPTPDTTLRAMQAIVGASACRSGDADTQAYVTDYRGIYRGQAQVVVLPSSTEEVSQ
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHH
VLQWCHARRVPVVPQGGNTSLMGGAVPDDSGTAVVVNLSRMNRVLDLDTINDTMTVQSGV
HHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCEEEEEHHHHCCEEEEECCCCCEEECCCC
TLSAARSAAEAWQRLFPLRIGSEGSCQIGGNLSTNAGGTAVLRYGNMRDLVLGIEVVLPD
CHHHHHHHHHHHHHHCCEEECCCCCEEECCCCCCCCCCEEEEEECCCEEEEEEEEEEECC
GRIYSSLRGLRKDNTGYDLKQLFVGAEGTLGIITGAVLKLMPQPRSSAVAFVAVQDPAAA
CHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCHHH
VALLGEAKRLSGQAVTAFELISRPALELVLEYLGNVASPLQDKHEWMVLIELTSGTDAES
HHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHH
LNATLMEILESGFSQGLVQDAAVAASLSDAQTFWRIREEISDAQTRTGGSIKCDVSVPLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHH
RIATFVEEASARVLELVPDARMVIYGHMGDGNVHFNPLRPRDQPGKEFLAQWYERVSALV
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHH
DGMAHAENGSISAEHGIGVAKRDDLTRYKSQVELELMWQVKQALDPLNLLNPGKVLPTPA
HHHHHCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]