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The map label for this gene is hexR [C]

Identifier: 116695011

GI number: 116695011

Start: 1204533

End: 1205366

Strand: Direct

Name: hexR [C]

Synonym: H16_B1066

Alternate gene names: 116695011

Gene position: 1204533-1205366 (Clockwise)

Preceding gene: 116695009

Following gene: 116695012

Centisome position: 41.36

GC content: 65.47

Gene sequence:

>834_bases
ATGCTCGCGCGCATCCACAGCATGCGGGACTCGCTGGGGCCGGCCGGGCAGCGCATTGCCGATTTCGTGACCCGGTATCC
GCAGACCGTGATCCATATGTCGGTCAGCGAAGTGGCCGAGCGCACCAATGCGAGCGAGGGCAGCGTGGTCGGCTTCTGCA
AGAGCCTGGGCGCGACGGGCTTCCAGCAACTGAAGATCCTGCTGGCGCAGGAACTGGTGCAGGGGGTCCAGATCATCCAC
GAAGACCTCGAGCCCGGCGACACCTGCCCGGCGGTCATGCGCAAGATCTTCCAGAGCAACGTCCAGACGCTGCATGACAC
CAGCGCCGTGCTCGACGTGGCCGCGATCGAGCGCGCGGTCGCATTGCTCAGGGCGGCCGAACGCATCGAGATCTATGGCA
TTGGCAGCGCGGCGCCGATCGCCGAGGATGCGCAGTACCGCATGCTGCGCATCGGGCTCAACGTGAAGGCGGTGGTGGAT
TCGCATATCCAGGCCATCAGCGCATCGCTCGCGGGCCCCAGGGTTGCCACGCTGACCATCTCGCATTCGGGCAGCACGCA
TGAAACCGTGACGGCCACGCGGCTGGCCCGGGAGAGCGGTGCCAGCACCATCTGCATCACCAATTTCGGCAAGTCGCCGA
TCCAGGCCTTCGCCGACGTCGTGCTGTTCACGATGGCGCGCGAGACCCGCTTCCGGACCGAGGCGATGACCAGCCGCCTG
GCGCAACTGGCGATCATCGATGTGCTGATCGCCTGCCTCGCGCTGACGGACTACGACACCTCCGTTGAAACGCTGCGGCG
TACGTTCGACGTCCTGTCGCTCAAGCGATATTGA

Upstream 100 bases:

>100_bases
CGCGGCGCCGGCCCGGAAATCGTCGTCGCAGGCGTCATCGGCCAGAACGGAGCCCGCGCAGACCGCCGAGCCAGCGCCGC
CGTCGCCCACCACGTCGGCG

Downstream 100 bases:

>100_bases
GCCTCGGCCGGCCCGCGCCGGCATCCTGACATATTCCTGCTGCAGTTGTCGTCCAGCCTTGCTCCCGTCAGTGACGGGGG
CGGGTGCCGTGCCACGGCCA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MLARIHSMRDSLGPAGQRIADFVTRYPQTVIHMSVSEVAERTNASEGSVVGFCKSLGATGFQQLKILLAQELVQGVQIIH
EDLEPGDTCPAVMRKIFQSNVQTLHDTSAVLDVAAIERAVALLRAAERIEIYGIGSAAPIAEDAQYRMLRIGLNVKAVVD
SHIQAISASLAGPRVATLTISHSGSTHETVTATRLARESGASTICITNFGKSPIQAFADVVLFTMARETRFRTEAMTSRL
AQLAIIDVLIACLALTDYDTSVETLRRTFDVLSLKRY

Sequences:

>Translated_277_residues
MLARIHSMRDSLGPAGQRIADFVTRYPQTVIHMSVSEVAERTNASEGSVVGFCKSLGATGFQQLKILLAQELVQGVQIIH
EDLEPGDTCPAVMRKIFQSNVQTLHDTSAVLDVAAIERAVALLRAAERIEIYGIGSAAPIAEDAQYRMLRIGLNVKAVVD
SHIQAISASLAGPRVATLTISHSGSTHETVTATRLARESGASTICITNFGKSPIQAFADVVLFTMARETRFRTEAMTSRL
AQLAIIDVLIACLALTDYDTSVETLRRTFDVLSLKRY
>Mature_277_residues
MLARIHSMRDSLGPAGQRIADFVTRYPQTVIHMSVSEVAERTNASEGSVVGFCKSLGATGFQQLKILLAQELVQGVQIIH
EDLEPGDTCPAVMRKIFQSNVQTLHDTSAVLDVAAIERAVALLRAAERIEIYGIGSAAPIAEDAQYRMLRIGLNVKAVVD
SHIQAISASLAGPRVATLTISHSGSTHETVTATRLARESGASTICITNFGKSPIQAFADVVLFTMARETRFRTEAMTSRL
AQLAIIDVLIACLALTDYDTSVETLRRTFDVLSLKRY

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=277, Percent_Identity=32.129963898917, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87082369, Length=251, Percent_Identity=29.0836653386454, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1788767, Length=278, Percent_Identity=28.4172661870504, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082130, Length=271, Percent_Identity=27.3062730627306, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30030; Mature: 30030

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLARIHSMRDSLGPAGQRIADFVTRYPQTVIHMSVSEVAERTNASEGSVVGFCKSLGATG
CCCHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCH
FQQLKILLAQELVQGVQIIHEDLEPGDTCPAVMRKIFQSNVQTLHDTSAVLDVAAIERAV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLRAAERIEIYGIGSAAPIAEDAQYRMLRIGLNVKAVVDSHIQAISASLAGPRVATLTI
HHHHHHHHEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEE
SHSGSTHETVTATRLARESGASTICITNFGKSPIQAFADVVLFTMARETRFRTEAMTSRL
ECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQLAIIDVLIACLALTDYDTSVETLRRTFDVLSLKRY
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLARIHSMRDSLGPAGQRIADFVTRYPQTVIHMSVSEVAERTNASEGSVVGFCKSLGATG
CCCHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCH
FQQLKILLAQELVQGVQIIHEDLEPGDTCPAVMRKIFQSNVQTLHDTSAVLDVAAIERAV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLRAAERIEIYGIGSAAPIAEDAQYRMLRIGLNVKAVVDSHIQAISASLAGPRVATLTI
HHHHHHHHEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEE
SHSGSTHETVTATRLARESGASTICITNFGKSPIQAFADVVLFTMARETRFRTEAMTSRL
ECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQLAIIDVLIACLALTDYDTSVETLRRTFDVLSLKRY
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]