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The map label for this gene is cyoB3 [H]

Identifier: 116694971

GI number: 116694971

Start: 1158837

End: 1160840

Strand: Direct

Name: cyoB3 [H]

Synonym: H16_B1026

Alternate gene names: 116694971

Gene position: 1158837-1160840 (Clockwise)

Preceding gene: 116694970

Following gene: 116694972

Centisome position: 39.79

GC content: 61.93

Gene sequence:

>2004_bases
ATGCCCGAGCGCTCGGAACTCGCCAATTTGATCTTCGGCCGGCTTTCGTGGGAGGCCCTCCCGCTGCACGATCCCATCCT
GCTCGGCACCTTCATCGTGGTGGTGATCGGTGGGGGCGCAATCGTCGCGGCGCTCACCTACTATCGCCTCTGGGGCTACC
TGTGGCGGGAATGGTTCACCAGCATCGACCACAAGAAGATCGGCATCATGTATGTGATCCTGGGCATCGTGATGCTGCTG
CGGGGTTTTGCCGACGCGATCATGATGCGCATCCAGCAGGCCATCGCGTTCGGCGACAACCTTGGCTACCTGCCGCCGCA
CCACTACGACCAGATCTTTACCGCGCACGGCGTGATCATGATCTTCTTCGTCGCCATGCCGCTGGTCACGGGGTTGATGA
ACTTCGTCATGCCGCTGCAGATCGGCGCGCGCGACGTGGCCTTCCCGTTCCTGAACAACTTCAGCTTCTGGATGACCACG
GGCGGTGCCATCCTGGTCATGATGTCGCTGTTCGTGGGCGAGTTCGCGCGCACCGGCTGGCTGGCCTATCCGCCCTTGTC
CGGCATCATCCACAGCCCTGACGTCGGCGTCGACTATTACATATGGGCGCTGCAGGTGGCCGGGGTAGGGACCTTGCTAT
CCGGCATCAACCTGCTGGTGACCATCGTCAAGATGCGGGCGCCCGGCATGACGCTGATGCGCATGCCGATCTTCACCTGG
ACCGCGCTGTGCACCAACGTGCTGATCATTGCCGCGTTCCCGGTGCTGACCGCGGCGCTGGCGCTGCTTGCGCTCGACCG
CTACGTCGGCACCAACTTCTTCACCACCGAGCTGGGCGGCAGCGCCATGATGTACGTGAACCTGATCTGGATATGGGGCC
ATCCGGAGGTGTACATCCTTGTGCTTCCGGTGTTCGGGGTGTTCTCGGAAGTGGTCGCCACGTTCTGCCGCAAGCGCCTG
TTCGGGTACGCGTCGATGGTCTACGCCACGGTAGTGATCACCGTGCTGTCGTACCTGGTCTGGTTGCACCATTTCTTCAC
GATGGGATCGGGCGCCAGCGTCAATTCGTTCTTCGGCATCACCACCATGATCATATCGATCCCGACCGGTGCCAAGATCT
TCAACTGGCTGTTCACGATGTACCACGGCAAGATCCGCTTCGAGCCCCCCATGCTCTGGACCATCGGCTTCATGGTCACG
TTCGTGATCGGCGGCATGACCGGCGTGCTGCTGGCGGTGCCGCCGGCTGACTTCTCCTTGCACAACAGCCTGTTCCTGAT
CGCGCATTTCCACAACGTGATCATCGGCGGCGTGCTGTTCGGCCTGATGGCAGGCATTACTTACTGGTTCCCGAAGGCAT
TCGGCTATCGCCTGGTCTCGTCCTGGGGCAAGGCATCGTTCTGGTTCTGGCTGGTCGGCTTCTACTTTGCGTTCATGCCG
CTGTACTGGCTGGGGCTGCATGGCGTGACCCGGCGCATGAGCCATTTCGAGGACGCGACGCACCAGGTCTGGTTCCAGCT
GGCTGCGTTCGGCGCCTTGCTGATCGCCATCGGCATTGCCTGCTTCCTGGTCCAGCTGGTGGTCAGCTTCATCCACCGCG
AGGAGCTTCGGGACCTGACTGGCGATCCGTGGAACGGCCGCACGCTCGAATGGTCGACTTCATCCCCGCCGCCGCAGTAC
AACTTTGCCTTTACGCCGGTAGTGCACGACACCGACGCCTGGTGGCACATGAAGCAGAATGGCTACGCGCGGCCGCAGCA
GGGCTTTATTCCGATCCATATGCCGAAGAACACCGCGGCCGGCATCGTGCTCGCGGGGTTCTCCACGCTCTGCGGTTTCG
CGTTGATCTGGCACATCTGGTGGCTGGCTGCAGCATCGTTCGCGGCGACGATCATCGGCGCGATCATCCATACGTTCAAC
TACCAGCGCGACTATTACCTCCCGGCCGACCTGGTGGTCCAGACCGAAGCGGCGCGCACACAACGGATGGCTGGCCATGG
CTGA

Upstream 100 bases:

>100_bases
CCGGGTGCTGCTGCAGTAAGGTGCGGATCCGGATCTTCCCTTGCGGTACTGGCCAGCCCCATCGGCCATGGTTGGTTAAT
TCAGGCCCCAGGTGACAAAC

Downstream 100 bases:

>100_bases
CACGACCTTTCCCAACCATGTGAGCGGCACCGGCACCGCGGACGCGGCCCCGCCGGGAGGCTACCAGTTCTACCTGCCCG
AAGACCATCACCCGCAGAAC

Product: bo3-type chinol oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 667; Mature: 666

Protein sequence:

>667_residues
MPERSELANLIFGRLSWEALPLHDPILLGTFIVVVIGGGAIVAALTYYRLWGYLWREWFTSIDHKKIGIMYVILGIVMLL
RGFADAIMMRIQQAIAFGDNLGYLPPHHYDQIFTAHGVIMIFFVAMPLVTGLMNFVMPLQIGARDVAFPFLNNFSFWMTT
GGAILVMMSLFVGEFARTGWLAYPPLSGIIHSPDVGVDYYIWALQVAGVGTLLSGINLLVTIVKMRAPGMTLMRMPIFTW
TALCTNVLIIAAFPVLTAALALLALDRYVGTNFFTTELGGSAMMYVNLIWIWGHPEVYILVLPVFGVFSEVVATFCRKRL
FGYASMVYATVVITVLSYLVWLHHFFTMGSGASVNSFFGITTMIISIPTGAKIFNWLFTMYHGKIRFEPPMLWTIGFMVT
FVIGGMTGVLLAVPPADFSLHNSLFLIAHFHNVIIGGVLFGLMAGITYWFPKAFGYRLVSSWGKASFWFWLVGFYFAFMP
LYWLGLHGVTRRMSHFEDATHQVWFQLAAFGALLIAIGIACFLVQLVVSFIHREELRDLTGDPWNGRTLEWSTSSPPPQY
NFAFTPVVHDTDAWWHMKQNGYARPQQGFIPIHMPKNTAAGIVLAGFSTLCGFALIWHIWWLAAASFAATIIGAIIHTFN
YQRDYYLPADLVVQTEAARTQRMAGHG

Sequences:

>Translated_667_residues
MPERSELANLIFGRLSWEALPLHDPILLGTFIVVVIGGGAIVAALTYYRLWGYLWREWFTSIDHKKIGIMYVILGIVMLL
RGFADAIMMRIQQAIAFGDNLGYLPPHHYDQIFTAHGVIMIFFVAMPLVTGLMNFVMPLQIGARDVAFPFLNNFSFWMTT
GGAILVMMSLFVGEFARTGWLAYPPLSGIIHSPDVGVDYYIWALQVAGVGTLLSGINLLVTIVKMRAPGMTLMRMPIFTW
TALCTNVLIIAAFPVLTAALALLALDRYVGTNFFTTELGGSAMMYVNLIWIWGHPEVYILVLPVFGVFSEVVATFCRKRL
FGYASMVYATVVITVLSYLVWLHHFFTMGSGASVNSFFGITTMIISIPTGAKIFNWLFTMYHGKIRFEPPMLWTIGFMVT
FVIGGMTGVLLAVPPADFSLHNSLFLIAHFHNVIIGGVLFGLMAGITYWFPKAFGYRLVSSWGKASFWFWLVGFYFAFMP
LYWLGLHGVTRRMSHFEDATHQVWFQLAAFGALLIAIGIACFLVQLVVSFIHREELRDLTGDPWNGRTLEWSTSSPPPQY
NFAFTPVVHDTDAWWHMKQNGYARPQQGFIPIHMPKNTAAGIVLAGFSTLCGFALIWHIWWLAAASFAATIIGAIIHTFN
YQRDYYLPADLVVQTEAARTQRMAGHG
>Mature_666_residues
PERSELANLIFGRLSWEALPLHDPILLGTFIVVVIGGGAIVAALTYYRLWGYLWREWFTSIDHKKIGIMYVILGIVMLLR
GFADAIMMRIQQAIAFGDNLGYLPPHHYDQIFTAHGVIMIFFVAMPLVTGLMNFVMPLQIGARDVAFPFLNNFSFWMTTG
GAILVMMSLFVGEFARTGWLAYPPLSGIIHSPDVGVDYYIWALQVAGVGTLLSGINLLVTIVKMRAPGMTLMRMPIFTWT
ALCTNVLIIAAFPVLTAALALLALDRYVGTNFFTTELGGSAMMYVNLIWIWGHPEVYILVLPVFGVFSEVVATFCRKRLF
GYASMVYATVVITVLSYLVWLHHFFTMGSGASVNSFFGITTMIISIPTGAKIFNWLFTMYHGKIRFEPPMLWTIGFMVTF
VIGGMTGVLLAVPPADFSLHNSLFLIAHFHNVIIGGVLFGLMAGITYWFPKAFGYRLVSSWGKASFWFWLVGFYFAFMPL
YWLGLHGVTRRMSHFEDATHQVWFQLAAFGALLIAIGIACFLVQLVVSFIHREELRDLTGDPWNGRTLEWSTSSPPPQYN
FAFTPVVHDTDAWWHMKQNGYARPQQGFIPIHMPKNTAAGIVLAGFSTLCGFALIWHIWWLAAASFAATIIGAIIHTFNY
QRDYYLPADLVVQTEAARTQRMAGHG

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=509, Percent_Identity=37.721021611002, Blast_Score=330, Evalue=3e-90,
Organism=Escherichia coli, GI1786634, Length=659, Percent_Identity=66.0091047040971, Blast_Score=903, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=511, Percent_Identity=36.399217221135, Blast_Score=332, Evalue=1e-91,
Organism=Saccharomyces cerevisiae, GI6226524, Length=325, Percent_Identity=40.9230769230769, Blast_Score=239, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6226523, Length=253, Percent_Identity=34.7826086956522, Blast_Score=137, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 74787; Mature: 74656

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPERSELANLIFGRLSWEALPLHDPILLGTFIVVVIGGGAIVAALTYYRLWGYLWREWFT
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
SIDHKKIGIMYVILGIVMLLRGFADAIMMRIQQAIAFGDNLGYLPPHHYDQIFTAHGVIM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
IFFVAMPLVTGLMNFVMPLQIGARDVAFPFLNNFSFWMTTGGAILVMMSLFVGEFARTGW
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCC
LAYPPLSGIIHSPDVGVDYYIWALQVAGVGTLLSGINLLVTIVKMRAPGMTLMRMPIFTW
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TALCTNVLIIAAFPVLTAALALLALDRYVGTNFFTTELGGSAMMYVNLIWIWGHPEVYIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEEEEECCCCEEEE
VLPVFGVFSEVVATFCRKRLFGYASMVYATVVITVLSYLVWLHHFFTMGSGASVNSFFGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
TTMIISIPTGAKIFNWLFTMYHGKIRFEPPMLWTIGFMVTFVIGGMTGVLLAVPPADFSL
HHHEEECCCCHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHCHHCEEEEECCCCCCC
HNSLFLIAHFHNVIIGGVLFGLMAGITYWFPKAFGYRLVSSWGKASFWFWLVGFYFAFMP
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LYWLGLHGVTRRMSHFEDATHQVWFQLAAFGALLIAIGIACFLVQLVVSFIHREELRDLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDPWNGRTLEWSTSSPPPQYNFAFTPVVHDTDAWWHMKQNGYARPQQGFIPIHMPKNTAA
CCCCCCCEEEECCCCCCCCCCEEECCEEECCCCCEEECCCCCCCCCCCEEEEECCCCCCC
GIVLAGFSTLCGFALIWHIWWLAAASFAATIIGAIIHTFNYQRDYYLPADLVVQTEAART
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHEEECHHHHH
QRMAGHG
HHHCCCC
>Mature Secondary Structure 
PERSELANLIFGRLSWEALPLHDPILLGTFIVVVIGGGAIVAALTYYRLWGYLWREWFT
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
SIDHKKIGIMYVILGIVMLLRGFADAIMMRIQQAIAFGDNLGYLPPHHYDQIFTAHGVIM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
IFFVAMPLVTGLMNFVMPLQIGARDVAFPFLNNFSFWMTTGGAILVMMSLFVGEFARTGW
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCC
LAYPPLSGIIHSPDVGVDYYIWALQVAGVGTLLSGINLLVTIVKMRAPGMTLMRMPIFTW
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TALCTNVLIIAAFPVLTAALALLALDRYVGTNFFTTELGGSAMMYVNLIWIWGHPEVYIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEEEEECCCCEEEE
VLPVFGVFSEVVATFCRKRLFGYASMVYATVVITVLSYLVWLHHFFTMGSGASVNSFFGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
TTMIISIPTGAKIFNWLFTMYHGKIRFEPPMLWTIGFMVTFVIGGMTGVLLAVPPADFSL
HHHEEECCCCHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHCHHCEEEEECCCCCCC
HNSLFLIAHFHNVIIGGVLFGLMAGITYWFPKAFGYRLVSSWGKASFWFWLVGFYFAFMP
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LYWLGLHGVTRRMSHFEDATHQVWFQLAAFGALLIAIGIACFLVQLVVSFIHREELRDLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDPWNGRTLEWSTSSPPPQYNFAFTPVVHDTDAWWHMKQNGYARPQQGFIPIHMPKNTAA
CCCCCCCEEEECCCCCCCCCCEEECCEEECCCCCEEECCCCCCCCCCCEEEEECCCCCCC
GIVLAGFSTLCGFALIWHIWWLAAASFAATIIGAIIHTFNYQRDYYLPADLVVQTEAART
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHEEECHHHHH
QRMAGHG
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]