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The map label for this gene is ccmE2 [H]

Identifier: 116694900

GI number: 116694900

Start: 1076900

End: 1077358

Strand: Direct

Name: ccmE2 [H]

Synonym: H16_B0955

Alternate gene names: 116694900

Gene position: 1076900-1077358 (Clockwise)

Preceding gene: 116694899

Following gene: 116694901

Centisome position: 36.98

GC content: 65.14

Gene sequence:

>459_bases
ATGAGGATGCTCAACAAGGCGCGCGGGCGACGCCTGCTCATGATCGCCGTGGGATTGCTGTTGCTTTGGACGGCTGCCGC
ATTGATCCTGAATGCCTTCCGCAGCAATATGGTGTTCTTCTTCTCGCCAAGCCAGCTCGCGGCAGGGGAGGGCCCGCGCG
ACAAGGCCTTCCGCCTTGGCGGCATGGTCGAGCGCGGCAGCCTGCGGCGCGCCCCGGATGGGCTGGGGGCGTCCTTCATA
CTGACCGATACGGTCAACCGGGTGCAGGTGGTCTACCGCGGCATGCTGCCCGATTTGTTTGGCGAAGGGCAGGGTGCCAT
TGCGTTCGGCCGCATGGGTGGCAACGGCATCTTCGCGGCCGAGGAGGTGCTGGCCAAGCATGATGAAGTGTACATGCCGC
CGGAGGTCGCCGCTTCGCTCAAGCTCGCCGAAGCGGCGCAGAAAGGTGGGGCCAGATGA

Upstream 100 bases:

>100_bases
TCCTGCTGGTACTGCGCTGCGGCGTGTCGACTCGGCGCACGCTGGCAGATGCGCACCCCGCCGCGCCCGGCATGCGGCTG
CAAGAGCAACGGGGTACGCA

Downstream 100 bases:

>100_bases
TTCCCGAACTCGGTCAATGGTGCCTGGCGCTTGCGCTCGCGCTGGCGCTGTCGCAAGCGGCGCTGCCGCTCCTGGGGGCG
GTGCGCGGCGTCGATGGCTG

Product: cytochrome c biogenesis factor

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MRMLNKARGRRLLMIAVGLLLLWTAAALILNAFRSNMVFFFSPSQLAAGEGPRDKAFRLGGMVERGSLRRAPDGLGASFI
LTDTVNRVQVVYRGMLPDLFGEGQGAIAFGRMGGNGIFAAEEVLAKHDEVYMPPEVAASLKLAEAAQKGGAR

Sequences:

>Translated_152_residues
MRMLNKARGRRLLMIAVGLLLLWTAAALILNAFRSNMVFFFSPSQLAAGEGPRDKAFRLGGMVERGSLRRAPDGLGASFI
LTDTVNRVQVVYRGMLPDLFGEGQGAIAFGRMGGNGIFAAEEVLAKHDEVYMPPEVAASLKLAEAAQKGGAR
>Mature_152_residues
MRMLNKARGRRLLMIAVGLLLLWTAAALILNAFRSNMVFFFSPSQLAAGEGPRDKAFRLGGMVERGSLRRAPDGLGASFI
LTDTVNRVQVVYRGMLPDLFGEGQGAIAFGRMGGNGIFAAEEVLAKHDEVYMPPEVAASLKLAEAAQKGGAR

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH [H]

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family [H]

Homologues:

Organism=Escherichia coli, GI1788525, Length=144, Percent_Identity=38.1944444444444, Blast_Score=100, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004329
- InterPro:   IPR012340 [H]

Pfam domain/function: PF03100 CcmE [H]

EC number: NA

Molecular weight: Translated: 16324; Mature: 16324

Theoretical pI: Translated: 10.93; Mature: 10.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMLNKARGRRLLMIAVGLLLLWTAAALILNAFRSNMVFFFSPSQLAAGEGPRDKAFRLG
CCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHCCCCCCCCHHHHHC
GMVERGSLRRAPDGLGASFILTDTVNRVQVVYRGMLPDLFGEGQGAIAFGRMGGNGIFAA
CCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHH
EEVLAKHDEVYMPPEVAASLKLAEAAQKGGAR
HHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRMLNKARGRRLLMIAVGLLLLWTAAALILNAFRSNMVFFFSPSQLAAGEGPRDKAFRLG
CCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHCCCCCCCCHHHHHC
GMVERGSLRRAPDGLGASFILTDTVNRVQVVYRGMLPDLFGEGQGAIAFGRMGGNGIFAA
CCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHH
EEVLAKHDEVYMPPEVAASLKLAEAAQKGGAR
HHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]