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The map label for this gene is mtaD [H]

Identifier: 116694808

GI number: 116694808

Start: 978170

End: 979618

Strand: Direct

Name: mtaD [H]

Synonym: H16_B0862

Alternate gene names: 116694808

Gene position: 978170-979618 (Clockwise)

Preceding gene: 116694807

Following gene: 116694809

Centisome position: 33.59

GC content: 70.95

Gene sequence:

>1449_bases
ATGACTGATCGTTCTGACTCGACGCCGGCCTGGCCCGGCGATACCAACCCGGCCCTGGTGCCGGACAGCTTCAGGCAGCC
GCGCATCCTGCTGCCGGAATGGACCTTGCTGCGCCAGGGCACGGTACGCGGCCACGCGGTGGTGGTGGAGGGCGGCCGCT
TCACGGCAGTGGGCACGGCCGCGGAAGTCGCCGCGCGCTTCCCCGAGCTGGAAACCCTGCCGCTGCCGCGCATGCTGCTG
ATGCCCGGCATGATCGACACGCACCACCACCTGACGCAGTCGTTCGGCAAGTCGCTGGTGTTCGGCGAACCATCGGAGAT
CTTCCGGCGCGTGTGGGTGCCGCTGGAAAGCAGCCTGAAGGCGGAGCACCTGTACCTGTCGTCCAAGCTGGCGGCGCTGG
AAGCGCTGCGCGGCGGCTTCACCACCGTGGTCGATGCCGGCACGCGCAGCGACGCCGGGCTGGATGCGGTCGCGCGCGCG
GTCGCCGATGCCGGCGTGCGCTGCGTGCTGGGCCTGATCTGCAACGACAAGCCCGGCGCCGAAACGCTCGACGCCGCGCC
GATCCTGCGCCGCGCCGCCGCCCACTTGGACAAGTACGCCAGCGATCCGCTGGTGGCCCCGTCGCTGGCGATCTCGATTC
CCGAGGTGGCCTCCGACGCGATGCTGCACCACGTCTACCAGTTGTGCGCCGAGTCCGGCCGCATCTTCCAGACCCATGCC
AACGAGCACCTGGTGGCGGTGGAGCGCTCGCTCAACGCCTGCGGGCGCCGTCCGATCGAACATCTCGCCGCAGTCGGCGC
ACTGGGTCCGGCGGCACTGCTGGCGCATGCCACGCTGGTGACGCCGCAAGAGATCCGCTTGCTGGCCGACACCGGCAGCG
CGGTGGCTTACAACCCCGTGGCCAGCGCCTGGAAGGGCAACGCCGTGGCACCGGCCGAGACCATGGCTACCTTCGGTGTG
CGCCTGGGCCTGGGCACCGATGGCACCCGCAGCGACGGCTTCCGCCTGCTGGACTATGCCGAGGCCGCCCAGCGCTTCGC
CTTCGGCATCGGCGTGGGCGATTCCTCCTGCGGCGCGGGCTGGCGCTGGGTCGACATGGCCACGCACGACGCGGCCGATG
TGGCGGGTCTCGGTGCGCTCACCGGCGAGATCGCCGCGGGCAAGCGCGCCGACTTCCTGCTGGTCGACCTGGACGTGCCT
GAGCTGACGCCGTCCTGGGACCTGACCTGGGAACTGGTGCGCCTGGCCAACCGCGACCAGATCCGCGCGGTCTTTGTCGA
TGGCAGCCTGCGCCTGTGGCAGGGCTGGCCCACGGACTGGGACGCACGCGCGCTGATGCGGGCGATCCACGCCATGGCCG
AGGACACCGTCGCCAACGCCCCGATCCGCAAGCTGCATGAAGCCGCGGACGTGCACCGAGTCCGCCATGCCGGCACGGAG
GCATCCTGA

Upstream 100 bases:

>100_bases
AACTTCCTGTTTTTCCATACGGGCCTGCGAGCCGCGGCAGCGGGCGCGGTTGCCCGCGACGATGCCGCCGCCACGCATTG
ACCCGGCTTCCTGAATTGCA

Downstream 100 bases:

>100_bases
CCATGGACATGACGTTGTTCAGCGTCGGCGTGGCGGTCTTTACCGGCGCGCTGGTCCAGGGTGCGACCGGCATGGGCTTC
GCGCTGATCGTGGTGCCGGT

Product: cytosine deaminase or related metal-dependent hydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MTDRSDSTPAWPGDTNPALVPDSFRQPRILLPEWTLLRQGTVRGHAVVVEGGRFTAVGTAAEVAARFPELETLPLPRMLL
MPGMIDTHHHLTQSFGKSLVFGEPSEIFRRVWVPLESSLKAEHLYLSSKLAALEALRGGFTTVVDAGTRSDAGLDAVARA
VADAGVRCVLGLICNDKPGAETLDAAPILRRAAAHLDKYASDPLVAPSLAISIPEVASDAMLHHVYQLCAESGRIFQTHA
NEHLVAVERSLNACGRRPIEHLAAVGALGPAALLAHATLVTPQEIRLLADTGSAVAYNPVASAWKGNAVAPAETMATFGV
RLGLGTDGTRSDGFRLLDYAEAAQRFAFGIGVGDSSCGAGWRWVDMATHDAADVAGLGALTGEIAAGKRADFLLVDLDVP
ELTPSWDLTWELVRLANRDQIRAVFVDGSLRLWQGWPTDWDARALMRAIHAMAEDTVANAPIRKLHEAADVHRVRHAGTE
AS

Sequences:

>Translated_482_residues
MTDRSDSTPAWPGDTNPALVPDSFRQPRILLPEWTLLRQGTVRGHAVVVEGGRFTAVGTAAEVAARFPELETLPLPRMLL
MPGMIDTHHHLTQSFGKSLVFGEPSEIFRRVWVPLESSLKAEHLYLSSKLAALEALRGGFTTVVDAGTRSDAGLDAVARA
VADAGVRCVLGLICNDKPGAETLDAAPILRRAAAHLDKYASDPLVAPSLAISIPEVASDAMLHHVYQLCAESGRIFQTHA
NEHLVAVERSLNACGRRPIEHLAAVGALGPAALLAHATLVTPQEIRLLADTGSAVAYNPVASAWKGNAVAPAETMATFGV
RLGLGTDGTRSDGFRLLDYAEAAQRFAFGIGVGDSSCGAGWRWVDMATHDAADVAGLGALTGEIAAGKRADFLLVDLDVP
ELTPSWDLTWELVRLANRDQIRAVFVDGSLRLWQGWPTDWDARALMRAIHAMAEDTVANAPIRKLHEAADVHRVRHAGTE
AS
>Mature_481_residues
TDRSDSTPAWPGDTNPALVPDSFRQPRILLPEWTLLRQGTVRGHAVVVEGGRFTAVGTAAEVAARFPELETLPLPRMLLM
PGMIDTHHHLTQSFGKSLVFGEPSEIFRRVWVPLESSLKAEHLYLSSKLAALEALRGGFTTVVDAGTRSDAGLDAVARAV
ADAGVRCVLGLICNDKPGAETLDAAPILRRAAAHLDKYASDPLVAPSLAISIPEVASDAMLHHVYQLCAESGRIFQTHAN
EHLVAVERSLNACGRRPIEHLAAVGALGPAALLAHATLVTPQEIRLLADTGSAVAYNPVASAWKGNAVAPAETMATFGVR
LGLGTDGTRSDGFRLLDYAEAAQRFAFGIGVGDSSCGAGWRWVDMATHDAADVAGLGALTGEIAAGKRADFLLVDLDVPE
LTPSWDLTWELVRLANRDQIRAVFVDGSLRLWQGWPTDWDARALMRAIHAMAEDTVANAPIRKLHEAADVHRVRHAGTEA
S

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Escherichia coli, GI87082177, Length=368, Percent_Identity=24.1847826086957, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319963, Length=337, Percent_Identity=21.3649851632047, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24643849, Length=387, Percent_Identity=24.031007751938, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 51545; Mature: 51414

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRSDSTPAWPGDTNPALVPDSFRQPRILLPEWTLLRQGTVRGHAVVVEGGRFTAVGTA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHCCCCCCCEEEEECCEEEEECHH
AEVAARFPELETLPLPRMLLMPGMIDTHHHLTQSFGKSLVFGEPSEIFRRVWVPLESSLK
HHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHCCCEECCCHHHHHHHHHCCHHCCCC
AEHLYLSSKLAALEALRGGFTTVVDAGTRSDAGLDAVARAVADAGVRCVLGLICNDKPGA
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHCCHHEEHHHHCCCCCCC
ETLDAAPILRRAAAHLDKYASDPLVAPSLAISIPEVASDAMLHHVYQLCAESGRIFQTHA
CHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECHHHHHHHHHHHHHHHHHCCCCEEEECC
NEHLVAVERSLNACGRRPIEHLAAVGALGPAALLAHATLVTPQEIRLLADTGSAVAYNPV
CCEEEHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHEEEEECCCCEEEECCH
ASAWKGNAVAPAETMATFGVRLGLGTDGTRSDGFRLLDYAEAAQRFAFGIGVGDSSCGAG
HHHCCCCCCCCHHHHHHHHEEEECCCCCCCCCCEEHHHHHHHHHHHEEEECCCCCCCCCC
WRWVDMATHDAADVAGLGALTGEIAAGKRADFLLVDLDVPELTPSWDLTWELVRLANRDQ
EEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCC
IRAVFVDGSLRLWQGWPTDWDARALMRAIHAMAEDTVANAPIRKLHEAADVHRVRHAGTE
EEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
AS
CC
>Mature Secondary Structure 
TDRSDSTPAWPGDTNPALVPDSFRQPRILLPEWTLLRQGTVRGHAVVVEGGRFTAVGTA
CCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHCCCCCCCEEEEECCEEEEECHH
AEVAARFPELETLPLPRMLLMPGMIDTHHHLTQSFGKSLVFGEPSEIFRRVWVPLESSLK
HHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHCCCEECCCHHHHHHHHHCCHHCCCC
AEHLYLSSKLAALEALRGGFTTVVDAGTRSDAGLDAVARAVADAGVRCVLGLICNDKPGA
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHCCHHEEHHHHCCCCCCC
ETLDAAPILRRAAAHLDKYASDPLVAPSLAISIPEVASDAMLHHVYQLCAESGRIFQTHA
CHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECHHHHHHHHHHHHHHHHHCCCCEEEECC
NEHLVAVERSLNACGRRPIEHLAAVGALGPAALLAHATLVTPQEIRLLADTGSAVAYNPV
CCEEEHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHEEEEECCCCEEEECCH
ASAWKGNAVAPAETMATFGVRLGLGTDGTRSDGFRLLDYAEAAQRFAFGIGVGDSSCGAG
HHHCCCCCCCCHHHHHHHHEEEECCCCCCCCCCEEHHHHHHHHHHHEEEECCCCCCCCCC
WRWVDMATHDAADVAGLGALTGEIAAGKRADFLLVDLDVPELTPSWDLTWELVRLANRDQ
EEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCC
IRAVFVDGSLRLWQGWPTDWDARALMRAIHAMAEDTVANAPIRKLHEAADVHRVRHAGTE
EEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
AS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA