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The map label for this gene is ydiO [C]

Identifier: 116694795

GI number: 116694795

Start: 962610

End: 963833

Strand: Direct

Name: ydiO [C]

Synonym: H16_B0849

Alternate gene names: 116694795

Gene position: 962610-963833 (Clockwise)

Preceding gene: 116694794

Following gene: 116694796

Centisome position: 33.05

GC content: 69.61

Gene sequence:

>1224_bases
ATGACAGATTCCATCACCACCGACGACGACGCGTCGCTGCAGGACTTCCGCCGCGAGGTGCGCGAGTTCGTCGCCCGGTC
GCTGCCCCATGCCGTGCGCGAGAAAGTCCGCCTCGGACTGGAACTCAGCAAGCCAGAGCTGGTCGACTGGCAGCGCCGGC
TGGCCGAACGCGGCTGGCTGGCGCCGCACTGGCCGGCTGAATGGCAGGGCTGCAACTGGAGCGCCGAGCGCCGCGCCGCA
TTCCAGGAAGAACTGGTGCTGGCGCACGCGCCCGAGAGCGGCGGCATCACCTTCGAGATGATCGGCCCGATCCTGATCCG
CTACGGCACGCCGGCGCAGCAGCAGTACTTCCTGCCGCGCATCCTGAACCAGGAGCACTGGTGGTGCCAGGGCTATTCCG
AACCGAACTCCGGCTCCGACCTGGCTTCGCTGAAGACGCGTGCGGTGCGCAAGACGCGGCCCGACGGCACCGAGGTCTAC
GTGGTCAGCGGCAGCAAGATCTGGACCTCCTACGCGCAGTACGCGGACTGGGTCTTCTGCCTGGTGCGCACCGATACCGA
GGCGCGCGCGCAGCGGGGCATCAGCTTCCTGCTGATCGACATGCGCAGCCCCGGCGTCAGCGTGCGGCCGCTGGTGGGCA
TCCATGGCTGGCACCTGTTCAACCAGGTGTTCTTCGACGAGGTGGAAGTGCCGGTGCAGAACCTCGTCGGCGAGGAGAAC
GCCGGCTGGACCATCGCCAAGTCCCTGCTCGAGCATGAGCGGCTGAACCTGGCGCGCGTGGCGGAGAACCGCCGCCGCCT
GGCCAAGGTGCGCGCCATCGGCAACGAGCTGGAGGAGGGCGGCCAGCCGCTGTCGCAGCGCCCGTGGTTTGCACGCCGGA
TGCGCGCGCTGGAGGTGCGGCTCGAAGCGCTGGCTGCAACCGTGCTGCGCTTTCGCAAGCGGGCGCGCGCCGGCGAAACG
CTGGGGCCGGAGACCGGCATGCTCAAGCTGCTGGGCAGCCGGCTGATCCAGGACATCGAGAACCTGGCGGTCGATGCGCT
GGGGCCGGACACGCTGGCCTATGACCGCGCCGCGCACTTCGAGCCCGCCGTGCCGCAAGCGGGACAGTCGGCGTACGCCG
CGGCGGCATCGGCGCGCCGCTTCGTCACCCGCGGCTACTCCATTGCCGGCGGCTCCAGCGAGATCCAGCACGAACTGCTG
GCCAAGCAGGTGCTGGGCCTGTAG

Upstream 100 bases:

>100_bases
CGGCTGATGGCGTGGCTGCGATCAAGGGCGGCATGCGCGCCGCGACGAGGCGCATGGCATCTGCTGCGCGCGACAAGAAT
TCCTGAGGACCGATATTTCC

Downstream 100 bases:

>100_bases
TGGCTCCAATCGTGCCCGCAACCCAGGACAAGGAACTGAACACATGAGCGATCCAACGGACGATCGCCGCATGCTGCAGG
AAAAGCGTGCGGCGCTATGT

Product: Acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; BCAD; SCAD [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MTDSITTDDDASLQDFRREVREFVARSLPHAVREKVRLGLELSKPELVDWQRRLAERGWLAPHWPAEWQGCNWSAERRAA
FQEELVLAHAPESGGITFEMIGPILIRYGTPAQQQYFLPRILNQEHWWCQGYSEPNSGSDLASLKTRAVRKTRPDGTEVY
VVSGSKIWTSYAQYADWVFCLVRTDTEARAQRGISFLLIDMRSPGVSVRPLVGIHGWHLFNQVFFDEVEVPVQNLVGEEN
AGWTIAKSLLEHERLNLARVAENRRRLAKVRAIGNELEEGGQPLSQRPWFARRMRALEVRLEALAATVLRFRKRARAGET
LGPETGMLKLLGSRLIQDIENLAVDALGPDTLAYDRAAHFEPAVPQAGQSAYAAAASARRFVTRGYSIAGGSSEIQHELL
AKQVLGL

Sequences:

>Translated_407_residues
MTDSITTDDDASLQDFRREVREFVARSLPHAVREKVRLGLELSKPELVDWQRRLAERGWLAPHWPAEWQGCNWSAERRAA
FQEELVLAHAPESGGITFEMIGPILIRYGTPAQQQYFLPRILNQEHWWCQGYSEPNSGSDLASLKTRAVRKTRPDGTEVY
VVSGSKIWTSYAQYADWVFCLVRTDTEARAQRGISFLLIDMRSPGVSVRPLVGIHGWHLFNQVFFDEVEVPVQNLVGEEN
AGWTIAKSLLEHERLNLARVAENRRRLAKVRAIGNELEEGGQPLSQRPWFARRMRALEVRLEALAATVLRFRKRARAGET
LGPETGMLKLLGSRLIQDIENLAVDALGPDTLAYDRAAHFEPAVPQAGQSAYAAAASARRFVTRGYSIAGGSSEIQHELL
AKQVLGL
>Mature_406_residues
TDSITTDDDASLQDFRREVREFVARSLPHAVREKVRLGLELSKPELVDWQRRLAERGWLAPHWPAEWQGCNWSAERRAAF
QEELVLAHAPESGGITFEMIGPILIRYGTPAQQQYFLPRILNQEHWWCQGYSEPNSGSDLASLKTRAVRKTRPDGTEVYV
VSGSKIWTSYAQYADWVFCLVRTDTEARAQRGISFLLIDMRSPGVSVRPLVGIHGWHLFNQVFFDEVEVPVQNLVGEENA
GWTIAKSLLEHERLNLARVAENRRRLAKVRAIGNELEEGGQPLSQRPWFARRMRALEVRLEALAATVLRFRKRARAGETL
GPETGMLKLLGSRLIQDIENLAVDALGPDTLAYDRAAHFEPAVPQAGQSAYAAAASARRFVTRGYSIAGGSSEIQHELLA
KQVLGL

Specific function: Has an optimum specificity for 4-carbon length fatty acyl-CoAs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=268, Percent_Identity=26.865671641791, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226958414, Length=224, Percent_Identity=27.6785714285714, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI7656849, Length=307, Percent_Identity=26.0586319218241, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4557235, Length=308, Percent_Identity=27.9220779220779, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI76496475, Length=308, Percent_Identity=27.9220779220779, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4557231, Length=248, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI187960098, Length=248, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI21361497, Length=221, Percent_Identity=26.2443438914027, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4557233, Length=308, Percent_Identity=25.6493506493506, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4501857, Length=207, Percent_Identity=28.5024154589372, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI48976061, Length=295, Percent_Identity=26.4406779661017, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI211971008, Length=295, Percent_Identity=26.4406779661017, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87081958, Length=285, Percent_Identity=24.2105263157895, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=252, Percent_Identity=26.984126984127, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=308, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71985184, Length=215, Percent_Identity=29.3023255813954, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71985192, Length=215, Percent_Identity=29.3023255813954, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17533517, Length=232, Percent_Identity=26.2931034482759, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=268, Percent_Identity=25.3731343283582, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551932, Length=246, Percent_Identity=25.609756097561, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=254, Percent_Identity=24.0157480314961, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17534899, Length=213, Percent_Identity=26.2910798122066, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281363737, Length=215, Percent_Identity=25.1162790697674, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355753, Length=158, Percent_Identity=34.1772151898734, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24666513, Length=162, Percent_Identity=32.7160493827161, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21356377, Length=215, Percent_Identity=26.5116279069767, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24660351, Length=205, Percent_Identity=26.3414634146341, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 45803; Mature: 45671

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSITTDDDASLQDFRREVREFVARSLPHAVREKVRLGLELSKPELVDWQRRLAERGWL
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCC
APHWPAEWQGCNWSAERRAAFQEELVLAHAPESGGITFEMIGPILIRYGTPAQQQYFLPR
CCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCEEHEECCCCCEECCCCHHHHHHHHH
ILNQEHWWCQGYSEPNSGSDLASLKTRAVRKTRPDGTEVYVVSGSKIWTSYAQYADWVFC
HCCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHEEE
LVRTDTEARAQRGISFLLIDMRSPGVSVRPLVGIHGWHLFNQVFFDEVEVPVQNLVGEEN
EEECCHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGWTIAKSLLEHERLNLARVAENRRRLAKVRAIGNELEEGGQPLSQRPWFARRMRALEVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LEALAATVLRFRKRARAGETLGPETGMLKLLGSRLIQDIENLAVDALGPDTLAYDRAAHF
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCC
EPAVPQAGQSAYAAAASARRFVTRGYSIAGGSSEIQHELLAKQVLGL
CCCCCCCCCHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDSITTDDDASLQDFRREVREFVARSLPHAVREKVRLGLELSKPELVDWQRRLAERGWL
CCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCC
APHWPAEWQGCNWSAERRAAFQEELVLAHAPESGGITFEMIGPILIRYGTPAQQQYFLPR
CCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCEEHEECCCCCEECCCCHHHHHHHHH
ILNQEHWWCQGYSEPNSGSDLASLKTRAVRKTRPDGTEVYVVSGSKIWTSYAQYADWVFC
HCCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHEEE
LVRTDTEARAQRGISFLLIDMRSPGVSVRPLVGIHGWHLFNQVFFDEVEVPVQNLVGEEN
EEECCHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGWTIAKSLLEHERLNLARVAENRRRLAKVRAIGNELEEGGQPLSQRPWFARRMRALEVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LEALAATVLRFRKRARAGETLGPETGMLKLLGSRLIQDIENLAVDALGPDTLAYDRAAHF
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCC
EPAVPQAGQSAYAAAASARRFVTRGYSIAGGSSEIQHELLAKQVLGL
CCCCCCCCCHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8399220; 7857927 [H]