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The map label for this gene is nadX

Identifier: 116694687

GI number: 116694687

Start: 829827

End: 830627

Strand: Direct

Name: nadX

Synonym: H16_B0736

Alternate gene names: 116694687

Gene position: 829827-830627 (Clockwise)

Preceding gene: 116694686

Following gene: 116694688

Centisome position: 28.49

GC content: 70.91

Gene sequence:

>801_bases
ATGCTGCATGTGTCCATGGTTGGCTGCGGCGCGATCGGCCGCGGCGTGATGGAATTGCTCAAGAGCGATCCCGAGGTGGT
GTTCGACGTGGTGATCGTGCCGGAGCACACGATGGACGAGGCCCGCGACGCGGTCACCGCGCTGGCGCCGGGCGCCCGCG
TGGCGACGCACCTGGACGACCAGCGTCCCGACCTGCTGGTCGAGTGCGCCGGCCACCATGCGCTGGAAGAGCACATCGTG
CCGGCGCTGGAACGCGGCATCCCGTGCATGGTGGTGTCGGTGGGCGCGCTGTCCGAGCCCGGCATGGCCGAGCGGCTGGA
AGCGGCCGCGCGCCGCGGCGGCACCCAGGTGCAGCTGTTGTCAGGTGCGATCGGCGCGATCGATGCGCTGGCCGCGGCGC
GTGTCGGCGGGCTGGACGAAGTCATCTACACCGGCCGCAAGCCGGCTCGCGCCTGGGCCGGCACGCCGGCCGAGCAGCTC
TTCGACCTGGATGCGCTGACCGAGGCGACCGTGATCTTCGAAGGCACGGCCCGCGACGCGGCGCGTCTGTATCCCAAGAA
CGCCAACGTGGCCGCCACGGTGTCGCTGGCAGGCTTGGGGCTGGACCGCACCTCGGTCAAGCTGCTGGCCGACCCGCATG
CGGTGGAGAACGTGCACCACGTGGAAGCGCGCGGCGCCTTCGGCGGCTTCGAGCTGACGATGCGCGGCAAGCCGCTGGCG
GCCAATCCCAAGACTTCCGCGCTGACCGTGTTCAGCGTGGTGCGCGCACTGGGAAACCGGGCGCACGCGGTATCGATCTA
G

Upstream 100 bases:

>100_bases
CGGTTCCTTCAAGACCATCTTCGCCGGCCCCCCGGTGAACAAGGACAACGAAGAGCCGGCGCGCGAACAAACCACTGTCA
CCGCCTGAGGGAGACCGGAG

Downstream 100 bases:

>100_bases
TCCCGGCAGCCAACGCCCCACAGACTTAGCAGGCAACGACAATGAAGACGCAAGAAGTACTCCCCATCTGCATCGCGGGC
GAATGGCGCCTGGGGACCGG

Product: L-aspartate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MLHVSMVGCGAIGRGVMELLKSDPEVVFDVVIVPEHTMDEARDAVTALAPGARVATHLDDQRPDLLVECAGHHALEEHIV
PALERGIPCMVVSVGALSEPGMAERLEAAARRGGTQVQLLSGAIGAIDALAAARVGGLDEVIYTGRKPARAWAGTPAEQL
FDLDALTEATVIFEGTARDAARLYPKNANVAATVSLAGLGLDRTSVKLLADPHAVENVHHVEARGAFGGFELTMRGKPLA
ANPKTSALTVFSVVRALGNRAHAVSI

Sequences:

>Translated_266_residues
MLHVSMVGCGAIGRGVMELLKSDPEVVFDVVIVPEHTMDEARDAVTALAPGARVATHLDDQRPDLLVECAGHHALEEHIV
PALERGIPCMVVSVGALSEPGMAERLEAAARRGGTQVQLLSGAIGAIDALAAARVGGLDEVIYTGRKPARAWAGTPAEQL
FDLDALTEATVIFEGTARDAARLYPKNANVAATVSLAGLGLDRTSVKLLADPHAVENVHHVEARGAFGGFELTMRGKPLA
ANPKTSALTVFSVVRALGNRAHAVSI
>Mature_266_residues
MLHVSMVGCGAIGRGVMELLKSDPEVVFDVVIVPEHTMDEARDAVTALAPGARVATHLDDQRPDLLVECAGHHALEEHIV
PALERGIPCMVVSVGALSEPGMAERLEAAARRGGTQVQLLSGAIGAIDALAAARVGGLDEVIYTGRKPARAWAGTPAEQL
FDLDALTEATVIFEGTARDAARLYPKNANVAATVSLAGLGLDRTSVKLLADPHAVENVHHVEARGAFGGFELTMRGKPLA
ANPKTSALTVFSVVRALGNRAHAVSI

Specific function: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate

COG id: COG1712

COG function: function code R; Predicted dinucleotide-utilizing enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L-aspartate dehydrogenase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASPD_CUPNH (Q0K391)

Other databases:

- EMBL:   AM260480
- RefSeq:   YP_728898.1
- ProteinModelPortal:   Q0K391
- SMR:   Q0K391
- STRING:   Q0K391
- GeneID:   4454967
- GenomeReviews:   AM260480_GR
- KEGG:   reh:H16_B0736
- eggNOG:   COG1712
- HOGENOM:   HBG649642
- OMA:   ECAGHSA
- ProtClustDB:   PRK13303
- BioCyc:   REUT381666:H16_B0736-MONOMER
- HAMAP:   MF_01265
- InterPro:   IPR005106
- InterPro:   IPR002811
- InterPro:   IPR011182
- InterPro:   IPR020626
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF005227

Pfam domain/function: PF01958 DUF108; PF03447 NAD_binding_3

EC number: =1.4.1.21

Molecular weight: Translated: 27776; Mature: 27776

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: ACT_SITE 219-219 BINDING 123-123 BINDING 189-189

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHVSMVGCGAIGRGVMELLKSDPEVVFDVVIVPEHTMDEARDAVTALAPGARVATHLDD
CEEEEEECCCHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCHHHHCCCC
QRPDLLVECAGHHALEEHIVPALERGIPCMVVSVGALSEPGMAERLEAAARRGGTQVQLL
CCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEE
SGAIGAIDALAAARVGGLDEVIYTGRKPARAWAGTPAEQLFDLDALTEATVIFEGTARDA
CCHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHCEEEEEECCCCHH
ARLYPKNANVAATVSLAGLGLDRTSVKLLADPHAVENVHHVEARGAFGGFELTMRGKPLA
HHHCCCCCCEEEEEEEEECCCCCCCEEEEECCHHHHCHHHHHHCCCCCCEEEEECCCCCC
ANPKTSALTVFSVVRALGNRAHAVSI
CCCCCHHHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure
MLHVSMVGCGAIGRGVMELLKSDPEVVFDVVIVPEHTMDEARDAVTALAPGARVATHLDD
CEEEEEECCCHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCHHHHCCCC
QRPDLLVECAGHHALEEHIVPALERGIPCMVVSVGALSEPGMAERLEAAARRGGTQVQLL
CCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEE
SGAIGAIDALAAARVGGLDEVIYTGRKPARAWAGTPAEQLFDLDALTEATVIFEGTARDA
CCHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHCEEEEEECCCCHH
ARLYPKNANVAATVSLAGLGLDRTSVKLLADPHAVENVHHVEARGAFGGFELTMRGKPLA
HHHCCCCCCEEEEEEEEECCCCCCCEEEEECCHHHHCHHHHHHCCCCCCEEEEECCCCCC
ANPKTSALTVFSVVRALGNRAHAVSI
CCCCCHHHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA