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The map label for this gene is rtxD2 [H]

Identifier: 116694642

GI number: 116694642

Start: 771599

End: 772987

Strand: Direct

Name: rtxD2 [H]

Synonym: H16_B0691

Alternate gene names: 116694642

Gene position: 771599-772987 (Clockwise)

Preceding gene: 116694641

Following gene: 116694643

Centisome position: 26.49

GC content: 67.82

Gene sequence:

>1389_bases
ATGTCGCTTCAGCCTGATCCGCAACGCATGGGGCCAGTGCGGCGCCTGATCGCCGCGCTGAGGCCACGTGCCGACGACAC
CGCCTTCATGTGCGAGCGCGATGCGGCCACGATGGCGCAACCGCGCTATTTCACGCACTGGATCCTCTGGTCCGCCCTGG
TCTTCGTGCTGGTGGCGCTGGCCTGGGCCGCGCTGGCGCGGGTGGACGAGGTGGCCGTGGGCGAGGGCAAGGTGATCCCG
TCGAGCCAGGTGCAGGTGGTGCAGAACCTCGAAGGCGGGATCATCGCCGAGATCATGGTGCGACCGGGGCAGGTGGTGAA
CAAGGACCAGCCGCTGATGCGCATCGACGATACACGCTTCACGGCTTCATACCAGGAAGGCCGCACCAGGGACGATGCGC
TGGTGGCACGCATTGCGCGCCTGAGCGCCGAGGCCGACGGCACGGCGTTCGTGGCGAGCGCGCCGGCCGATGCCGAGGGC
CGCCGCTTCGTGTCCGAGGAGCGCGCGCTGTTCGAGTCACGCAAGCGCGCGTTCGATGCCAATCTCGCCGTGCTGCGCCA
GCAGTCCGAGCAGCGGCGGCAGGAGCTGACCGAGAAGCGCTCGCGCGAGCAGCAACTGCGGCAGAGCCATCGGCTGGTGG
CACAGGAGCTGGCCATGATGCGCCCGATGATGGCGCAGGGCGTCGTGTCCGAGGTCGACCTGCTGCGGCTGGAGCGCCAG
GCCAATGACCTGAAAGGCGAGCTCGAGGCCGCGCGGCTCGCCATGCCGCGCCTGGAGGCCGCCTACCGCGAGAGCCAGCA
AAAAGCCGACGAACTGGGCACGCATTATCGTGCCGAGGCCATGAAAGAGCTCAACCAGGCCAAGGCCGAACAGGCCGCGC
AGAGCGCCACCAACACCGCGCTGCAGGACCGCGTCGACCGTACCCTGGTACGCGCCCCGCTTGCGGGCGTCATCAAGCAG
ATCAAGATCAATACCGTTGGCGGCGTGGTGCAGCCCGGCATGGATCTGCTGGAGATCGTCCCGCTGGAAGACACGCTGCT
GGTAGAGGCGCGCGTGCGGCCTGCCGACATTGCCTTCCTGCGGCCCGGCCAGCCGGCGGTGGTCAAGCTGTCGGCCTATG
ACTTTTCGATCTATGGCGGCTTTGCCGGCACCGTGGAGCATATCAGCGCCGATACGCTGACACCGGAGCGCCCGGGCGAG
CGCCCGGAAAGCTACTACCTGGTGCGCGTGCGCACGCGCGACAACCGGCCAGGCGGCAGTGCCGTGCAGGTGCCCATCCT
GCCCGGCATGGTGGCGACGGTCGATGTGCTGACCGGGCAGAAGACGGTGCTCCATTACCTGCTCAAGCCCATCATCAAGA
CCAGGGAACTGGCGTTCCGGGAACGATAA

Upstream 100 bases:

>100_bases
CTCAGCCTGGTCGATCGCCTGATCGTGATGGACCAGGGCCGTATCGTCGCCGATGGTCCCAAGGCCGAAGTCCTGAACGC
GCTCGCGGGGAGGAAGCTCC

Downstream 100 bases:

>100_bases
GAGCGGGCGGTTTGCCCACGACGACAACAAGCAAGGCATGGCCAGCAGGCTGGCATTCAGGACGGAGAGTGATCATGGCA
ACCCTGACAGGTAGCAACGG

Product: RTX toxin membrane fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSLQPDPQRMGPVRRLIAALRPRADDTAFMCERDAATMAQPRYFTHWILWSALVFVLVALAWAALARVDEVAVGEGKVIP
SSQVQVVQNLEGGIIAEIMVRPGQVVNKDQPLMRIDDTRFTASYQEGRTRDDALVARIARLSAEADGTAFVASAPADAEG
RRFVSEERALFESRKRAFDANLAVLRQQSEQRRQELTEKRSREQQLRQSHRLVAQELAMMRPMMAQGVVSEVDLLRLERQ
ANDLKGELEAARLAMPRLEAAYRESQQKADELGTHYRAEAMKELNQAKAEQAAQSATNTALQDRVDRTLVRAPLAGVIKQ
IKINTVGGVVQPGMDLLEIVPLEDTLLVEARVRPADIAFLRPGQPAVVKLSAYDFSIYGGFAGTVEHISADTLTPERPGE
RPESYYLVRVRTRDNRPGGSAVQVPILPGMVATVDVLTGQKTVLHYLLKPIIKTRELAFRER

Sequences:

>Translated_462_residues
MSLQPDPQRMGPVRRLIAALRPRADDTAFMCERDAATMAQPRYFTHWILWSALVFVLVALAWAALARVDEVAVGEGKVIP
SSQVQVVQNLEGGIIAEIMVRPGQVVNKDQPLMRIDDTRFTASYQEGRTRDDALVARIARLSAEADGTAFVASAPADAEG
RRFVSEERALFESRKRAFDANLAVLRQQSEQRRQELTEKRSREQQLRQSHRLVAQELAMMRPMMAQGVVSEVDLLRLERQ
ANDLKGELEAARLAMPRLEAAYRESQQKADELGTHYRAEAMKELNQAKAEQAAQSATNTALQDRVDRTLVRAPLAGVIKQ
IKINTVGGVVQPGMDLLEIVPLEDTLLVEARVRPADIAFLRPGQPAVVKLSAYDFSIYGGFAGTVEHISADTLTPERPGE
RPESYYLVRVRTRDNRPGGSAVQVPILPGMVATVDVLTGQKTVLHYLLKPIIKTRELAFRER
>Mature_461_residues
SLQPDPQRMGPVRRLIAALRPRADDTAFMCERDAATMAQPRYFTHWILWSALVFVLVALAWAALARVDEVAVGEGKVIPS
SQVQVVQNLEGGIIAEIMVRPGQVVNKDQPLMRIDDTRFTASYQEGRTRDDALVARIARLSAEADGTAFVASAPADAEGR
RFVSEERALFESRKRAFDANLAVLRQQSEQRRQELTEKRSREQQLRQSHRLVAQELAMMRPMMAQGVVSEVDLLRLERQA
NDLKGELEAARLAMPRLEAAYRESQQKADELGTHYRAEAMKELNQAKAEQAAQSATNTALQDRVDRTLVRAPLAGVIKQI
KINTVGGVVQPGMDLLEIVPLEDTLLVEARVRPADIAFLRPGQPAVVKLSAYDFSIYGGFAGTVEHISADTLTPERPGER
PESYYLVRVRTRDNRPGGSAVQVPILPGMVATVDVLTGQKTVLHYLLKPIIKTRELAFRER

Specific function: Involved in the secretion of alkaline protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 51432; Mature: 51301

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQPDPQRMGPVRRLIAALRPRADDTAFMCERDAATMAQPRYFTHWILWSALVFVLVAL
CCCCCCHHHHHHHHHHHHHHCCCCCCCHHEECCCHHHHCCCHHHHHHHHHHHHHHHHHHH
AWAALARVDEVAVGEGKVIPSSQVQVVQNLEGGIIAEIMVRPGQVVNKDQPLMRIDDTRF
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEHEEECCCHHCCCCCCCEEECCCCE
TASYQEGRTRDDALVARIARLSAEADGTAFVASAPADAEGRRFVSEERALFESRKRAFDA
EECHHCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
NLAVLRQQSEQRRQELTEKRSREQQLRQSHRLVAQELAMMRPMMAQGVVSEVDLLRLERQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANDLKGELEAARLAMPRLEAAYRESQQKADELGTHYRAEAMKELNQAKAEQAAQSATNTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQDRVDRTLVRAPLAGVIKQIKINTVGGVVQPGMDLLEIVPLEDTLLVEARVRPADIAFL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHEEECCCCEEEEEECCCCCCEEEE
RPGQPAVVKLSAYDFSIYGGFAGTVEHISADTLTPERPGERPESYYLVRVRTRDNRPGGS
CCCCCCEEEEEEEEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCC
AVQVPILPGMVATVDVLTGQKTVLHYLLKPIIKTRELAFRER
EEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLQPDPQRMGPVRRLIAALRPRADDTAFMCERDAATMAQPRYFTHWILWSALVFVLVAL
CCCCCHHHHHHHHHHHHHHCCCCCCCHHEECCCHHHHCCCHHHHHHHHHHHHHHHHHHH
AWAALARVDEVAVGEGKVIPSSQVQVVQNLEGGIIAEIMVRPGQVVNKDQPLMRIDDTRF
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEHEEECCCHHCCCCCCCEEECCCCE
TASYQEGRTRDDALVARIARLSAEADGTAFVASAPADAEGRRFVSEERALFESRKRAFDA
EECHHCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
NLAVLRQQSEQRRQELTEKRSREQQLRQSHRLVAQELAMMRPMMAQGVVSEVDLLRLERQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANDLKGELEAARLAMPRLEAAYRESQQKADELGTHYRAEAMKELNQAKAEQAAQSATNTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQDRVDRTLVRAPLAGVIKQIKINTVGGVVQPGMDLLEIVPLEDTLLVEARVRPADIAFL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHEEECCCCEEEEEECCCCCCEEEE
RPGQPAVVKLSAYDFSIYGGFAGTVEHISADTLTPERPGERPESYYLVRVRTRDNRPGGS
CCCCCCEEEEEEEEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCC
AVQVPILPGMVATVDVLTGQKTVLHYLLKPIIKTRELAFRER
EEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]