BacMap

Definition	Ralstonia eutropha H16 chromosome 2, complete sequence.
Accession	NC_008314
Length	2,912,490

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The map label for this gene is dmpC [H]

Identifier: 116694498

GI number: 116694498

Start: 617282

End: 618760

Strand: Direct

Name: dmpC [H]

Synonym: H16_B0547

Alternate gene names: 116694498

Gene position: 617282-618760 (Clockwise)

Preceding gene: 116694497

Following gene: 116694499

Centisome position: 21.19

GC content: 69.3

Gene sequence:

>1479_bases
ATGCTTCAATACCAGAGAAACAACATGAAAGACTTCAAGAACTTCATCAACGGCGAGTGGGTCGGCACCGCGCGGACCTT
CGAGAACCGCAATCCGGCCGACAACAGCCTGATCGGCCACGTGCACGAGGCCGGACAGGCCGAGGTCGACGCCGCGGTGC
GGGCCGCGCGCAGCGCGCTGCAGGGACCGTGGGGCCGCATGACGGTGGCGCAGCGGGTCGAGCTGCTGCACGCGGTGGCC
GACGGCATCAACCGCCGCTTCGACGAATTCGTGCAGGCCGAGATTGCCGATACCGGCAAGCCCTTCGGGCTGGCCAGTCA
TATCGACATCCCGCGCGGCGCGGCCAACTTCAAGGTCTTTGCCGACCTGATCCGCAACGTGCCGACCGAAAGCTTTGCCA
TGGACACGCCCGACGGCGGCAAGGCCATCAACTACGCGGTGCGCAGCCCGCGCGGCGTGATCGGCGTGGTGTGCCCGTGG
AACCTGCCGCTGCTGCTGATGACATGGAAGGTCGGGCCGGCGCTGGCCTGCGGCAACACCGTGGTGGTCAAGCCCTCGGA
GGAGACCCCCGCCACCGCGACGCTGCTGGGCGAGGTGATGAACGAGGCCGGCGTGCCGCCCGGCGTCTACAACGTGGTGC
ACGGCTTTGGCCCGGATTCGGCCGGCGCGTTCCTGACCGCGCACCCGCAGGTCAACGGCATCACCTTCACCGGCGAGACC
CGCACCGGCGAGGCCATCATGAAGGCAGCGGCCAACGGCGTGCGGCCGGTGTCGTTCGAGCTGGGCGGCAAGAACGCGGG
CATCGTGTTCGCCGATGCGGATTTCGACAAGGCCGTGGCCGGCATCACGCGCTCGGCGTTCGAGAACAGCGGCCAGGTGT
GCCTGGGCACCGAGCGCGTCTACGTGCAGCGGCCGATCTTCGAGCGCTTTGTCGCCGCGCTGAAGGCGAAGGCCGAGGGC
CTGAAGCTGGGTCGGCCCACCGAGCCCGGCGTGAACATGGGCCCGCTGGTGTCGCACGAGCACCGCGACAAGGTGCTGTC
CTACTACCGCAAGGCCGCCGGGGCCGGCGCCACCGTGGTCACCGGCGGCGGCGTGCCGCAGATGCCGGGGGCGCTGGCCG
AAGGCGCCTGGGTGCAGCCCACCATCTGGACCGGCCTGCCGGAAAGCGCCGCCGTGATCCGCGAGGAGATCTTCGGGCCG
TGCTGCCATATCGCCCCGTTCGACACCGAAGAGGAAGTCATCGCGCTGGCCAACGACACCCCGTACGGCCTGGCCGCCAC
GGTCTGGACCGGCGACCTCGGCACCGCGCACCGCATGGGCAGCGCGCTGGACGTTGGCATCTGCTGGATCAATGCCTGGT
TCCTGCGCGACCTGCGCACCGCCTTTGGCGGCGCCAGGCAGTCCGGCATCGGCCGCGAGGGCGGTGTCCATTCGCTCGAG
TTCTACACCGAGCTGCGCAACGTCTGCGTCCGCCTGTGA

Upstream 100 bases:

>100_bases
CTGACCTGAGCGCGAACGCTCGCCTCCCGCTCGTTTGCTCCCTCTCCCGCTTGCGGGAGAGGGAGCACCCAATCGATGAG
CGGAGGATTGCCGTGCACGA

Downstream 100 bases:

>100_bases
GGTCCCGTCATGCATAACGAACTTATCCTTGAGATCGGCGCCGGCCTGCACCATGCGCTGGCCTCCCGTCGCCCGGTGGC
GCCGCTGACCGAATCGTGGC

Product: 2-hydroxymuconic semialdehyde dehydrogenase

Products: 5-carboxymethyl-2-hydroxymuconate; NADH; H+

Alternate protein names: HMSD [H]

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MLQYQRNNMKDFKNFINGEWVGTARTFENRNPADNSLIGHVHEAGQAEVDAAVRAARSALQGPWGRMTVAQRVELLHAVA
DGINRRFDEFVQAEIADTGKPFGLASHIDIPRGAANFKVFADLIRNVPTESFAMDTPDGGKAINYAVRSPRGVIGVVCPW
NLPLLLMTWKVGPALACGNTVVVKPSEETPATATLLGEVMNEAGVPPGVYNVVHGFGPDSAGAFLTAHPQVNGITFTGET
RTGEAIMKAAANGVRPVSFELGGKNAGIVFADADFDKAVAGITRSAFENSGQVCLGTERVYVQRPIFERFVAALKAKAEG
LKLGRPTEPGVNMGPLVSHEHRDKVLSYYRKAAGAGATVVTGGGVPQMPGALAEGAWVQPTIWTGLPESAAVIREEIFGP
CCHIAPFDTEEEVIALANDTPYGLAATVWTGDLGTAHRMGSALDVGICWINAWFLRDLRTAFGGARQSGIGREGGVHSLE
FYTELRNVCVRL

Sequences:

>Translated_492_residues
MLQYQRNNMKDFKNFINGEWVGTARTFENRNPADNSLIGHVHEAGQAEVDAAVRAARSALQGPWGRMTVAQRVELLHAVA
DGINRRFDEFVQAEIADTGKPFGLASHIDIPRGAANFKVFADLIRNVPTESFAMDTPDGGKAINYAVRSPRGVIGVVCPW
NLPLLLMTWKVGPALACGNTVVVKPSEETPATATLLGEVMNEAGVPPGVYNVVHGFGPDSAGAFLTAHPQVNGITFTGET
RTGEAIMKAAANGVRPVSFELGGKNAGIVFADADFDKAVAGITRSAFENSGQVCLGTERVYVQRPIFERFVAALKAKAEG
LKLGRPTEPGVNMGPLVSHEHRDKVLSYYRKAAGAGATVVTGGGVPQMPGALAEGAWVQPTIWTGLPESAAVIREEIFGP
CCHIAPFDTEEEVIALANDTPYGLAATVWTGDLGTAHRMGSALDVGICWINAWFLRDLRTAFGGARQSGIGREGGVHSLE
FYTELRNVCVRL
>Mature_492_residues
MLQYQRNNMKDFKNFINGEWVGTARTFENRNPADNSLIGHVHEAGQAEVDAAVRAARSALQGPWGRMTVAQRVELLHAVA
DGINRRFDEFVQAEIADTGKPFGLASHIDIPRGAANFKVFADLIRNVPTESFAMDTPDGGKAINYAVRSPRGVIGVVCPW
NLPLLLMTWKVGPALACGNTVVVKPSEETPATATLLGEVMNEAGVPPGVYNVVHGFGPDSAGAFLTAHPQVNGITFTGET
RTGEAIMKAAANGVRPVSFELGGKNAGIVFADADFDKAVAGITRSAFENSGQVCLGTERVYVQRPIFERFVAALKAKAEG
LKLGRPTEPGVNMGPLVSHEHRDKVLSYYRKAAGAGATVVTGGGVPQMPGALAEGAWVQPTIWTGLPESAAVIREEIFGP
CCHIAPFDTEEEVIALANDTPYGLAATVWTGDLGTAHRMGSALDVGICWINAWFLRDLRTAFGGARQSGIGREGGVHSLE
FYTELRNVCVRL

Specific function: 2-hydroxymuconic acid semialdehyde can be converted to 2-hydroxypent-2,4-dienoate either directly by the action of 2- hydroxymuconic semialdehyde hydrolase (HMSH) or by the action of three sequential enzymes, the first of which is HMSD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=487, Percent_Identity=40.6570841889117, Blast_Score=401, Evalue=1e-112,
Organism=Homo sapiens, GI153266822, Length=485, Percent_Identity=38.1443298969072, Blast_Score=333, Evalue=2e-91,
Organism=Homo sapiens, GI25952152, Length=487, Percent_Identity=37.3716632443532, Blast_Score=330, Evalue=2e-90,
Organism=Homo sapiens, GI25777732, Length=483, Percent_Identity=37.888198757764, Blast_Score=328, Evalue=8e-90,
Organism=Homo sapiens, GI115387104, Length=473, Percent_Identity=37.8435517970402, Blast_Score=325, Evalue=4e-89,
Organism=Homo sapiens, GI25777724, Length=489, Percent_Identity=36.8098159509202, Blast_Score=325, Evalue=6e-89,
Organism=Homo sapiens, GI25777730, Length=483, Percent_Identity=38.0952380952381, Blast_Score=322, Evalue=4e-88,
Organism=Homo sapiens, GI21361176, Length=485, Percent_Identity=37.5257731958763, Blast_Score=322, Evalue=6e-88,
Organism=Homo sapiens, GI25777728, Length=427, Percent_Identity=36.0655737704918, Blast_Score=288, Evalue=6e-78,
Organism=Homo sapiens, GI301500698, Length=487, Percent_Identity=33.0595482546201, Blast_Score=275, Evalue=5e-74,
Organism=Homo sapiens, GI25777726, Length=489, Percent_Identity=32.9243353783231, Blast_Score=270, Evalue=3e-72,
Organism=Homo sapiens, GI238814322, Length=486, Percent_Identity=33.7448559670782, Blast_Score=268, Evalue=8e-72,
Organism=Homo sapiens, GI21614513, Length=480, Percent_Identity=35, Blast_Score=266, Evalue=4e-71,
Organism=Homo sapiens, GI4507229, Length=479, Percent_Identity=36.7432150313152, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI25777721, Length=492, Percent_Identity=35.9756097560976, Blast_Score=242, Evalue=5e-64,
Organism=Homo sapiens, GI11095441, Length=482, Percent_Identity=28.0082987551867, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI188035924, Length=485, Percent_Identity=27.6288659793814, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI310128093, Length=478, Percent_Identity=27.6150627615063, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI310128103, Length=478, Percent_Identity=27.6150627615063, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI310128091, Length=473, Percent_Identity=28.5412262156448, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI223972651, Length=497, Percent_Identity=28.169014084507, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI206597441, Length=448, Percent_Identity=27.2321428571429, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI206597439, Length=448, Percent_Identity=27.2321428571429, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI22907049, Length=448, Percent_Identity=27.2321428571429, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI310128089, Length=327, Percent_Identity=30.5810397553517, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI310128097, Length=261, Percent_Identity=32.9501915708812, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI71773324, Length=346, Percent_Identity=28.0346820809249, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4502043, Length=346, Percent_Identity=28.0346820809249, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI238814371, Length=346, Percent_Identity=28.0346820809249, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI73466520, Length=444, Percent_Identity=25, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4557303, Length=444, Percent_Identity=25, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI73695881, Length=342, Percent_Identity=27.4853801169591, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI73695879, Length=342, Percent_Identity=27.4853801169591, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI310128095, Length=315, Percent_Identity=29.5238095238095, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI223972653, Length=343, Percent_Identity=29.1545189504373, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI238859541, Length=462, Percent_Identity=26.4069264069264, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI25777736, Length=462, Percent_Identity=26.4069264069264, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI25777734, Length=462, Percent_Identity=26.4069264069264, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI310128087, Length=298, Percent_Identity=24.1610738255034, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1786504, Length=489, Percent_Identity=39.6728016359918, Blast_Score=333, Evalue=2e-92,
Organism=Escherichia coli, GI1787558, Length=483, Percent_Identity=38.3022774327122, Blast_Score=322, Evalue=3e-89,
Organism=Escherichia coli, GI87082295, Length=487, Percent_Identity=37.1663244353183, Blast_Score=314, Evalue=8e-87,
Organism=Escherichia coli, GI87081896, Length=464, Percent_Identity=36.2068965517241, Blast_Score=294, Evalue=1e-80,
Organism=Escherichia coli, GI1789015, Length=496, Percent_Identity=35.8870967741936, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI1787715, Length=480, Percent_Identity=36.25, Blast_Score=277, Evalue=9e-76,
Organism=Escherichia coli, GI1787684, Length=486, Percent_Identity=33.5390946502058, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI87081926, Length=463, Percent_Identity=28.5097192224622, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1788042, Length=418, Percent_Identity=29.4258373205742, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1787250, Length=466, Percent_Identity=29.1845493562232, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1787653, Length=446, Percent_Identity=25.5605381165919, Blast_Score=93, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17551164, Length=480, Percent_Identity=42.0833333333333, Blast_Score=355, Evalue=4e-98,
Organism=Caenorhabditis elegans, GI25144435, Length=483, Percent_Identity=37.888198757764, Blast_Score=321, Evalue=4e-88,
Organism=Caenorhabditis elegans, GI17562198, Length=486, Percent_Identity=37.8600823045267, Blast_Score=320, Evalue=1e-87,
Organism=Caenorhabditis elegans, GI71995606, Length=483, Percent_Identity=38.7163561076605, Blast_Score=304, Evalue=7e-83,
Organism=Caenorhabditis elegans, GI25143876, Length=480, Percent_Identity=35.625, Blast_Score=290, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI25143874, Length=480, Percent_Identity=35.625, Blast_Score=289, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI133930964, Length=494, Percent_Identity=35.0202429149798, Blast_Score=288, Evalue=6e-78,
Organism=Caenorhabditis elegans, GI32564736, Length=427, Percent_Identity=37.9391100702576, Blast_Score=287, Evalue=7e-78,
Organism=Caenorhabditis elegans, GI71995613, Length=422, Percent_Identity=40.0473933649289, Blast_Score=268, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI17534119, Length=478, Percent_Identity=32.8451882845188, Blast_Score=228, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI71986308, Length=483, Percent_Identity=31.4699792960663, Blast_Score=209, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI115534176, Length=490, Percent_Identity=27.9591836734694, Blast_Score=166, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17534447, Length=471, Percent_Identity=27.3885350318471, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI32564151, Length=434, Percent_Identity=26.4976958525346, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI115532534, Length=349, Percent_Identity=30.0859598853868, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI25146394, Length=346, Percent_Identity=26.878612716763, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25146391, Length=346, Percent_Identity=26.878612716763, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32566756, Length=346, Percent_Identity=26.878612716763, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17564084, Length=350, Percent_Identity=27.7142857142857, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71990744, Length=289, Percent_Identity=28.0276816608997, Blast_Score=92, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6320917, Length=487, Percent_Identity=38.3983572895277, Blast_Score=323, Evalue=5e-89,
Organism=Saccharomyces cerevisiae, GI6324950, Length=489, Percent_Identity=36.40081799591, Blast_Score=310, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6323821, Length=487, Percent_Identity=33.6755646817248, Blast_Score=285, Evalue=9e-78,
Organism=Saccharomyces cerevisiae, GI6323822, Length=492, Percent_Identity=33.739837398374, Blast_Score=282, Evalue=8e-77,
Organism=Saccharomyces cerevisiae, GI6325196, Length=488, Percent_Identity=31.5573770491803, Blast_Score=265, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6319478, Length=479, Percent_Identity=32.9853862212944, Blast_Score=262, Evalue=8e-71,
Organism=Saccharomyces cerevisiae, GI6321828, Length=479, Percent_Identity=27.5574112734864, Blast_Score=163, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6321826, Length=512, Percent_Identity=25.390625, Blast_Score=97, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6323757, Length=312, Percent_Identity=27.5641025641026, Blast_Score=90, Evalue=9e-19,
Organism=Drosophila melanogaster, GI20129399, Length=484, Percent_Identity=37.1900826446281, Blast_Score=328, Evalue=5e-90,
Organism=Drosophila melanogaster, GI24650465, Length=485, Percent_Identity=37.9381443298969, Blast_Score=308, Evalue=6e-84,
Organism=Drosophila melanogaster, GI281362580, Length=482, Percent_Identity=34.8547717842324, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI62472918, Length=482, Percent_Identity=34.8547717842324, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI62472926, Length=482, Percent_Identity=34.8547717842324, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI62472936, Length=482, Percent_Identity=34.8547717842324, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI21356737, Length=482, Percent_Identity=34.8547717842324, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24585660, Length=482, Percent_Identity=33.6099585062241, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24638876, Length=483, Percent_Identity=28.1573498964803, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24638878, Length=483, Percent_Identity=28.1573498964803, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24666674, Length=496, Percent_Identity=26.4112903225806, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24668425, Length=470, Percent_Identity=25.3191489361702, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24668417, Length=470, Percent_Identity=25.3191489361702, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24668413, Length=470, Percent_Identity=25.3191489361702, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281360299, Length=343, Percent_Identity=26.530612244898, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281360297, Length=343, Percent_Identity=26.530612244898, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281360295, Length=343, Percent_Identity=26.530612244898, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24586250, Length=343, Percent_Identity=26.530612244898, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281360301, Length=343, Percent_Identity=26.530612244898, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281360303, Length=343, Percent_Identity=26.530612244898, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI45552499, Length=343, Percent_Identity=26.530612244898, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28571798, Length=453, Percent_Identity=22.5165562913907, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28571796, Length=453, Percent_Identity=22.5165562913907, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28571794, Length=453, Percent_Identity=22.5165562913907, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28571806, Length=453, Percent_Identity=22.5165562913907, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28571802, Length=453, Percent_Identity=22.5165562913907, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28571800, Length=453, Percent_Identity=22.5165562913907, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28574525, Length=469, Percent_Identity=24.7334754797441, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281360293, Length=157, Percent_Identity=33.1210191082803, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR017628 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: 1.2.1.60

Molecular weight: Translated: 52533; Mature: 52533

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQYQRNNMKDFKNFINGEWVGTARTFENRNPADNSLIGHVHEAGQAEVDAAVRAARSAL
CCCCCCCCHHHHHHHHCCCEEEEEHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
QGPWGRMTVAQRVELLHAVADGINRRFDEFVQAEIADTGKPFGLASHIDIPRGAANFKVF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
ADLIRNVPTESFAMDTPDGGKAINYAVRSPRGVIGVVCPWNLPLLLMTWKVGPALACGNT
HHHHHCCCCCCEECCCCCCCCEEEEEECCCCCCEEEECCCCCCEEEEEECCCCCEECCCE
VVVKPSEETPATATLLGEVMNEAGVPPGVYNVVHGFGPDSAGAFLTAHPQVNGITFTGET
EEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEECCCCCCEEEECCC
RTGEAIMKAAANGVRPVSFELGGKNAGIVFADADFDKAVAGITRSAFENSGQVCLGTERV
CCHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEECCEE
YVQRPIFERFVAALKAKAEGLKLGRPTEPGVNMGPLVSHEHRDKVLSYYRKAAGAGATVV
EEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
TGGGVPQMPGALAEGAWVQPTIWTGLPESAAVIREEIFGPCCHIAPFDTEEEVIALANDT
ECCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCEEEEECCC
PYGLAATVWTGDLGTAHRMGSALDVGICWINAWFLRDLRTAFGGARQSGIGREGGVHSLE
CCCEEEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHH
FYTELRNVCVRL
HHHHHHHHHHCC
>Mature Secondary Structure
MLQYQRNNMKDFKNFINGEWVGTARTFENRNPADNSLIGHVHEAGQAEVDAAVRAARSAL
CCCCCCCCHHHHHHHHCCCEEEEEHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
QGPWGRMTVAQRVELLHAVADGINRRFDEFVQAEIADTGKPFGLASHIDIPRGAANFKVF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
ADLIRNVPTESFAMDTPDGGKAINYAVRSPRGVIGVVCPWNLPLLLMTWKVGPALACGNT
HHHHHCCCCCCEECCCCCCCCEEEEEECCCCCCEEEECCCCCCEEEEEECCCCCEECCCE
VVVKPSEETPATATLLGEVMNEAGVPPGVYNVVHGFGPDSAGAFLTAHPQVNGITFTGET
EEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEECCCCCCEEEECCC
RTGEAIMKAAANGVRPVSFELGGKNAGIVFADADFDKAVAGITRSAFENSGQVCLGTERV
CCHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEECCEE
YVQRPIFERFVAALKAKAEGLKLGRPTEPGVNMGPLVSHEHRDKVLSYYRKAAGAGATVV
EEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
TGGGVPQMPGALAEGAWVQPTIWTGLPESAAVIREEIFGPCCHIAPFDTEEEVIALANDT
ECCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCEEEEECCC
PYGLAATVWTGDLGTAHRMGSALDVGICWINAWFLRDLRTAFGGARQSGIGREGGVHSLE
CCCEEEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHH
FYTELRNVCVRL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-carboxymethyl-2-hydroxymuconate semialdehyde; H2O; NAD+

Specific reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2194577 [H]