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The map label for this gene is xylE [H]

Identifier: 116694497

GI number: 116694497

Start: 616255

End: 617190

Strand: Direct

Name: xylE [H]

Synonym: H16_B0546

Alternate gene names: 116694497

Gene position: 616255-617190 (Clockwise)

Preceding gene: 116694496

Following gene: 116694498

Centisome position: 21.16

GC content: 63.14

Gene sequence:

>936_bases
ATGGCATTGACAGGCGTATTGCGACCGGGGCATGTAGCCCTGCGCGTGCTGGAGCTGGAACCGGCGCTGAAACACTACAC
CGAGGTACTCGGCTTGATCGAAACCGCGCGCGATGCGCAGGGCCGGGTGTTCCTGAAGGCATGGGACGAGCACGACCACC
ACAGCGTGGTGCTGCGCGAGGCCGACAGTCCGGGCATGGACTACATGGGTTTTCGCGTCGACAGCGGCCACACGCTGGAG
CGGCTGGCGCAGGAGGTGGAGCAATCCGGCCTGGCCAGCGATTGCAAGTGGATCGCCGCGGGCGAGCACCCGCATACCGG
CGTGCGCTTTCGCTTCACCATCCCGACAGGGCATGCGATCGAACTCTTTGCCGACAAGGACAAGCTTGGCTGCAAGACCG
GCGACCTCAATCCCGACCCCTGGCCGGACGACCTGCGCGGCATGGCGCCCAGCCGCTTCGACCACTGCCTGCTGTATGGC
GACGATGTCGACGGCACCGTCAAGTTGTTCCGCGACGTGCTGGGCTTTTCTCTGGCCGAGCAGGTCGTGGCCGGGGCCGA
CGGCGAGATGCTGATCGGTGCCTTCCTGACCTGCTCGAACAAGGCGCACGACATTGCCTTTATCCGCCACCCGGAGAAGA
ACCGCTTCCACCATGCCTCGTTCCTGCTTGATAACTGGAGCGAAGTGTTGAAGGCGGCCGACATCATCTCCAAGAAGGAC
GTGTCGCTCGACATCGGCCCGACCCGTCACGGCATTACGCGTGGCGCGACGATCTACTTCTTCGATCCCTCGGGCAACCG
CAACGAGGTCTTCTCCGGCGGCTATATCCACTACCCGGACAAGCCCACCATCACCTGGACCGATAACGAGCTGGGGCGCG
CGATCTTCTACCACGACAGGAAGCTGAACGAAGCGTTCTTGAATGTGCTGACCTGA

Upstream 100 bases:

>100_bases
AGCAGCGGTGGCGCGAACAGGGCCGGTAGCACGCAAACGAAGCACAAGCAAGGAAGGTGGCACCCACACAACGCCACCCC
ACCACACCAGGAGACCCATC

Downstream 100 bases:

>100_bases
GCGCGAACGCTCGCCTCCCGCTCGTTTGCTCCCTCTCCCGCTTGCGGGAGAGGGAGCACCCAATCGATGAGCGGAGGATT
GCCGTGCACGAATGCTTCAA

Product: catechol 2,3-dioxygenase

Products: NA

Alternate protein names: MPC; CatO2ase; Catechol 2,3-dioxygenase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MALTGVLRPGHVALRVLELEPALKHYTEVLGLIETARDAQGRVFLKAWDEHDHHSVVLREADSPGMDYMGFRVDSGHTLE
RLAQEVEQSGLASDCKWIAAGEHPHTGVRFRFTIPTGHAIELFADKDKLGCKTGDLNPDPWPDDLRGMAPSRFDHCLLYG
DDVDGTVKLFRDVLGFSLAEQVVAGADGEMLIGAFLTCSNKAHDIAFIRHPEKNRFHHASFLLDNWSEVLKAADIISKKD
VSLDIGPTRHGITRGATIYFFDPSGNRNEVFSGGYIHYPDKPTITWTDNELGRAIFYHDRKLNEAFLNVLT

Sequences:

>Translated_311_residues
MALTGVLRPGHVALRVLELEPALKHYTEVLGLIETARDAQGRVFLKAWDEHDHHSVVLREADSPGMDYMGFRVDSGHTLE
RLAQEVEQSGLASDCKWIAAGEHPHTGVRFRFTIPTGHAIELFADKDKLGCKTGDLNPDPWPDDLRGMAPSRFDHCLLYG
DDVDGTVKLFRDVLGFSLAEQVVAGADGEMLIGAFLTCSNKAHDIAFIRHPEKNRFHHASFLLDNWSEVLKAADIISKKD
VSLDIGPTRHGITRGATIYFFDPSGNRNEVFSGGYIHYPDKPTITWTDNELGRAIFYHDRKLNEAFLNVLT
>Mature_310_residues
ALTGVLRPGHVALRVLELEPALKHYTEVLGLIETARDAQGRVFLKAWDEHDHHSVVLREADSPGMDYMGFRVDSGHTLER
LAQEVEQSGLASDCKWIAAGEHPHTGVRFRFTIPTGHAIELFADKDKLGCKTGDLNPDPWPDDLRGMAPSRFDHCLLYGD
DVDGTVKLFRDVLGFSLAEQVVAGADGEMLIGAFLTCSNKAHDIAFIRHPEKNRFHHASFLLDNWSEVLKAADIISKKDV
SLDIGPTRHGITRGATIYFFDPSGNRNEVFSGGYIHYPDKPTITWTDNELGRAIFYHDRKLNEAFLNVLT

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the extradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017624
- InterPro:   IPR004360
- InterPro:   IPR000486 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: =1.13.11.2 [H]

Molecular weight: Translated: 34730; Mature: 34598

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00082 EXTRADIOL_DIOXYGENAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTGVLRPGHVALRVLELEPALKHYTEVLGLIETARDAQGRVFLKAWDEHDHHSVVLRE
CCCCCCCCCCHHEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEE
ADSPGMDYMGFRVDSGHTLERLAQEVEQSGLASDCKWIAAGEHPHTGVRFRFTIPTGHAI
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEECCCCCEE
ELFADKDKLGCKTGDLNPDPWPDDLRGMAPSRFDHCLLYGDDVDGTVKLFRDVLGFSLAE
EEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
QVVAGADGEMLIGAFLTCSNKAHDIAFIRHPEKNRFHHASFLLDNWSEVLKAADIISKKD
HHHHCCCCCEEEEEEEECCCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHCCCC
VSLDIGPTRHGITRGATIYFFDPSGNRNEVFSGGYIHYPDKPTITWTDNELGRAIFYHDR
CEEECCCCCCCCCCCCEEEEECCCCCCCCEECCCEEECCCCCEEEECCCCCCCEEEEECC
KLNEAFLNVLT
HHHHHHHHHCC
>Mature Secondary Structure 
ALTGVLRPGHVALRVLELEPALKHYTEVLGLIETARDAQGRVFLKAWDEHDHHSVVLRE
CCCCCCCCCHHEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEE
ADSPGMDYMGFRVDSGHTLERLAQEVEQSGLASDCKWIAAGEHPHTGVRFRFTIPTGHAI
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEECCCCCEE
ELFADKDKLGCKTGDLNPDPWPDDLRGMAPSRFDHCLLYGDDVDGTVKLFRDVLGFSLAE
EEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
QVVAGADGEMLIGAFLTCSNKAHDIAFIRHPEKNRFHHASFLLDNWSEVLKAADIISKKD
HHHHCCCCCEEEEEEEECCCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHCCCC
VSLDIGPTRHGITRGATIYFFDPSGNRNEVFSGGYIHYPDKPTITWTDNELGRAIFYHDR
CEEECCCCCCCCCCCCEEEEECCCCCCCCEECCCEEECCCCCEEEECCCCCCCEEEEECC
KLNEAFLNVLT
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1672868 [H]