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The map label for this gene is yogA [H]

Identifier: 116694468

GI number: 116694468

Start: 582415

End: 583488

Strand: Direct

Name: yogA [H]

Synonym: H16_B0517

Alternate gene names: 116694468

Gene position: 582415-583488 (Clockwise)

Preceding gene: 116694466

Following gene: 116694473

Centisome position: 20.0

GC content: 70.2

Gene sequence:

>1074_bases
ATGGCGCTGGCAGGGAATCAGTATAGTGGGTTCACCGTTTTCAACAGACCGGAGTACCCCATGACTTCCTCCATGCAGCG
CTGGCAACTGTCCGCTTTCGGCCGCAACAACCTGCGTCGCGTCGACGCGCCCATTCCCGTGCCCGGTCCCGGCGAGGTGC
TGGTGCGGGTCCATGCCGTGGCCTTGAACTACCGCGACCTGCTGATCATCCAGGACGGCATGGGCATGCCCGTGCAGCCG
CCGCTGGTTCTCGGGTCGGACATGCGCGGCGAGGTGGTGGCGAGTGGCGATGGTGTAGCCGACTTTGCCCCTGGCGACGC
CGTGATCAGCACCTTCTTCACCGGCTGGCTCGATGGCGTGCAGCCGCACCGCAGCATGCCGCTGGGCGTGCCGGGTCCCG
GCATGCTGTCGGAGTACGTGGTATTGGCAGAGGACTCGCTGGTGTCGGCCCCGCGCACGCTGGACGCCGCGCAGGCCAGC
ACGCTGACCTGCGCCGGCCTGACGGCCTGGCAAGCCCTGGCTGAAGCGACGGTGACGCGGCCCGGCGACACCGTCGTGGT
GATCGGCACCGGCGGAGTGGCCCTGTTTGCGGTGCAGATCGCCCGCGCACAGGGGGCGCGCGTGATCGTGGTGTCAGGCA
GCGACGACAAGCTGGCGCGCGTGCAGGAGCTGGGCGCGGCGCATGGCGTCCATCGCGGCCGCACCGCTGACTGGCCGGCT
GCCGTGCGCGAGCTGACCGGAGGCCGCGGTGCCGACCATGTGCTGGAACTGGCTGGCGGAGACAACTTCGGCCGGTCGCT
TGCCGCGCTGGCGCAGGGCGGCCGGATCTCGGTGATCGGCAACCTTCAGGGGGATGAGCTGCGCGCCAGCGTCTATCCGG
TGCTGCATGGCCGCGTGACCGTGCAGGGGATCGGCGTGTCGCACCGGCGCGCGCTGCAGGACCTGGTGCGTGCCGTGGAC
TGGTTGGGGCTGCGCCCGGTGATCGAGAGCGAGTACGGGTTCGGGGACTTGCCCGCGGCGCTCGACCACCTGGAACGCGG
GGCCTTCGGCAAGGTGGTGGTGCGGCTGCGCTGA

Upstream 100 bases:

>100_bases
CTGCCGGCCTCCGCGGCGGCAACGAAGGCGGAGATCCCGGCCAGCCGGTCATGGGTAATTGGTTCCATAAGATCTACATG
AGAAGGACATCGATTGCCCA

Downstream 100 bases:

>100_bases
GGCGCGGGCCGGACTGCTATTTGCGAGCCTTGCCGCGCACGCTCTTCTTGGCCGCGGCGGCGCGCGCCGCTTCTTTTTCG
GCCGCTGCCGCCGCGCCCAA

Product: Zn-dependent alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MALAGNQYSGFTVFNRPEYPMTSSMQRWQLSAFGRNNLRRVDAPIPVPGPGEVLVRVHAVALNYRDLLIIQDGMGMPVQP
PLVLGSDMRGEVVASGDGVADFAPGDAVISTFFTGWLDGVQPHRSMPLGVPGPGMLSEYVVLAEDSLVSAPRTLDAAQAS
TLTCAGLTAWQALAEATVTRPGDTVVVIGTGGVALFAVQIARAQGARVIVVSGSDDKLARVQELGAAHGVHRGRTADWPA
AVRELTGGRGADHVLELAGGDNFGRSLAALAQGGRISVIGNLQGDELRASVYPVLHGRVTVQGIGVSHRRALQDLVRAVD
WLGLRPVIESEYGFGDLPAALDHLERGAFGKVVVRLR

Sequences:

>Translated_357_residues
MALAGNQYSGFTVFNRPEYPMTSSMQRWQLSAFGRNNLRRVDAPIPVPGPGEVLVRVHAVALNYRDLLIIQDGMGMPVQP
PLVLGSDMRGEVVASGDGVADFAPGDAVISTFFTGWLDGVQPHRSMPLGVPGPGMLSEYVVLAEDSLVSAPRTLDAAQAS
TLTCAGLTAWQALAEATVTRPGDTVVVIGTGGVALFAVQIARAQGARVIVVSGSDDKLARVQELGAAHGVHRGRTADWPA
AVRELTGGRGADHVLELAGGDNFGRSLAALAQGGRISVIGNLQGDELRASVYPVLHGRVTVQGIGVSHRRALQDLVRAVD
WLGLRPVIESEYGFGDLPAALDHLERGAFGKVVVRLR
>Mature_356_residues
ALAGNQYSGFTVFNRPEYPMTSSMQRWQLSAFGRNNLRRVDAPIPVPGPGEVLVRVHAVALNYRDLLIIQDGMGMPVQPP
LVLGSDMRGEVVASGDGVADFAPGDAVISTFFTGWLDGVQPHRSMPLGVPGPGMLSEYVVLAEDSLVSAPRTLDAAQAST
LTCAGLTAWQALAEATVTRPGDTVVVIGTGGVALFAVQIARAQGARVIVVSGSDDKLARVQELGAAHGVHRGRTADWPAA
VRELTGGRGADHVLELAGGDNFGRSLAALAQGGRISVIGNLQGDELRASVYPVLHGRVTVQGIGVSHRRALQDLVRAVDW
LGLRPVIESEYGFGDLPAALDHLERGAFGKVVVRLR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=328, Percent_Identity=26.8292682926829, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI13236495, Length=328, Percent_Identity=26.8292682926829, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI47519420, Length=380, Percent_Identity=27.1052631578947, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI22538446, Length=340, Percent_Identity=27.9411764705882, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI22538444, Length=340, Percent_Identity=27.9411764705882, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI28557745, Length=364, Percent_Identity=27.1978021978022, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI194239676, Length=214, Percent_Identity=28.9719626168224, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI24308257, Length=351, Percent_Identity=23.6467236467236, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI67078404, Length=266, Percent_Identity=27.8195488721804, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87082125, Length=342, Percent_Identity=26.0233918128655, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790045, Length=332, Percent_Identity=24.6987951807229, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789651, Length=259, Percent_Identity=30.1158301158301, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081918, Length=329, Percent_Identity=27.355623100304, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788075, Length=258, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790485, Length=238, Percent_Identity=26.890756302521, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=209, Percent_Identity=29.1866028708134, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17507255, Length=343, Percent_Identity=27.1137026239067, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319520, Length=257, Percent_Identity=29.1828793774319, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323729, Length=336, Percent_Identity=24.702380952381, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323961, Length=334, Percent_Identity=25.4491017964072, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=334, Percent_Identity=25.4491017964072, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322619, Length=321, Percent_Identity=26.4797507788162, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319955, Length=321, Percent_Identity=26.4797507788162, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6319621, Length=340, Percent_Identity=25.5882352941176, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24581339, Length=388, Percent_Identity=28.6082474226804, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24581341, Length=380, Percent_Identity=28.9473684210526, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 37612; Mature: 37481

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALAGNQYSGFTVFNRPEYPMTSSMQRWQLSAFGRNNLRRVDAPIPVPGPGEVLVRVHAV
CCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEEEEEE
ALNYRDLLIIQDGMGMPVQPPLVLGSDMRGEVVASGDGVADFAPGDAVISTFFTGWLDGV
EECCCEEEEEECCCCCCCCCCEEECCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCC
QPHRSMPLGVPGPGMLSEYVVLAEDSLVSAPRTLDAAQASTLTCAGLTAWQALAEATVTR
CCCCCCCCCCCCCCHHHCEEEEECCCHHCCCCCCCHHHCCEEEEHHHHHHHHHHHHHCCC
PGDTVVVIGTGGVALFAVQIARAQGARVIVVSGSDDKLARVQELGAAHGVHRGRTADWPA
CCCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHH
AVRELTGGRGADHVLELAGGDNFGRSLAALAQGGRISVIGNLQGDELRASVYPVLHGRVT
HHHHHCCCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHEEEEEEECEEE
VQGIGVSHRRALQDLVRAVDWLGLRPVIESEYGFGDLPAALDHLERGAFGKVVVRLR
EEECCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure 
ALAGNQYSGFTVFNRPEYPMTSSMQRWQLSAFGRNNLRRVDAPIPVPGPGEVLVRVHAV
CCCCCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEEEEEE
ALNYRDLLIIQDGMGMPVQPPLVLGSDMRGEVVASGDGVADFAPGDAVISTFFTGWLDGV
EECCCEEEEEECCCCCCCCCCEEECCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCC
QPHRSMPLGVPGPGMLSEYVVLAEDSLVSAPRTLDAAQASTLTCAGLTAWQALAEATVTR
CCCCCCCCCCCCCCHHHCEEEEECCCHHCCCCCCCHHHCCEEEEHHHHHHHHHHHHHCCC
PGDTVVVIGTGGVALFAVQIARAQGARVIVVSGSDDKLARVQELGAAHGVHRGRTADWPA
CCCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHH
AVRELTGGRGADHVLELAGGDNFGRSLAALAQGGRISVIGNLQGDELRASVYPVLHGRVT
HHHHHCCCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHEEEEEEECEEE
VQGIGVSHRRALQDLVRAVDWLGLRPVIESEYGFGDLPAALDHLERGAFGKVVVRLR
EEECCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]