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The map label for this gene is gbpR [H]

Identifier: 116694435

GI number: 116694435

Start: 548292

End: 549185

Strand: Direct

Name: gbpR [H]

Synonym: H16_B0484

Alternate gene names: 116694435

Gene position: 548292-549185 (Clockwise)

Preceding gene: 116694432

Following gene: 116694439

Centisome position: 18.83

GC content: 67.9

Gene sequence:

>894_bases
ATGCGTATCCGCCAGCTGCATGTGCTGGTGGCGCTACATGAAACCCGCAATGTCAGCCGTACCGCTGCGCGCCTGAACAT
GACCCAGCCAGCCCTGTCGCGCTGGCTGGCCGAGCTGGAGAGTGAACTGGGGGTGGCGCTGTTCGAGCGGCATTCGCGCG
GCCTGGTGCCGACCCGCTTCTGCGAAGCGCTGGTCGTACATGCCCGCACCATCCTCAATGAGATCGAACGCACCCAGGCC
ACCATTCGCGTGATGGCAGAAGGCGCGGCTGGGCAACTGGCGATCGGCGCGACGCCAACCGTATCGGTCGACCTGCTGCC
GTCGGCGATCAGCCGGTTCCGCGAGCGCTTTCCCGATGCCCACCTGACGCTGGCAGAGGGCACCGTCGAAGACATGCTGC
CGGCCCTGCGCGAAGGACGGCTGGACTTCGTCATGGGGCGTACCGAAGTGCAGGGCATCGACGGCGAGCTGCGCTGCGAC
CTGCTATATCCGGAGACCATCCGCGTGATCGCCGGCCCCACGCATCCGCTTGCGCGCAAGCGCAAGGTCGGGTGGGCGGA
TACGCGCGCCTATACCTGGGTGGGGCCGCCCGTGACCAGCCAGATCCGGCGCGAGCTGGACTACGAACTGGCACTGGCCG
GCGAACCCGCCCCATGTGTGCGGATCGAGAGCGCGACGTTGCTTGCCAACGTGTCGCTGCTGCAGCAGGGAGAACTGCTG
GCCGTGATGTCAGGCCGGATGGCAGCGTTCTTCAGTCGCCTGGGGCAGGTGGCGATATTGCGGCTGCCATACCGGCGCGA
GGGCATGGTCGGCGTGCTCCGGCGCCGGGACACCGAGCAGACGCCGCTGCGGCAGGCGTTCATGGACGCGCTGGCTGCCA
GCGCGCACGGATAG

Upstream 100 bases:

>100_bases
GGGGGATGGAAAAATTATTGCATCGTCCGCGATTCCATTGAAATGATTAATATGACCTCTGCTATAACCTGAAACTCATA
CCATGGACTGGACCCAACGG

Downstream 100 bases:

>100_bases
TCAGATAGTCAGCAAGGACGCAATCCGGCTACCGCGCCGGTTGCCTCGCATCTGGCTCAGGCCCACTCCCCTCCAGCGCC
GCCCCACGCGCCTCCATCGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MRIRQLHVLVALHETRNVSRTAARLNMTQPALSRWLAELESELGVALFERHSRGLVPTRFCEALVVHARTILNEIERTQA
TIRVMAEGAAGQLAIGATPTVSVDLLPSAISRFRERFPDAHLTLAEGTVEDMLPALREGRLDFVMGRTEVQGIDGELRCD
LLYPETIRVIAGPTHPLARKRKVGWADTRAYTWVGPPVTSQIRRELDYELALAGEPAPCVRIESATLLANVSLLQQGELL
AVMSGRMAAFFSRLGQVAILRLPYRREGMVGVLRRRDTEQTPLRQAFMDALAASAHG

Sequences:

>Translated_297_residues
MRIRQLHVLVALHETRNVSRTAARLNMTQPALSRWLAELESELGVALFERHSRGLVPTRFCEALVVHARTILNEIERTQA
TIRVMAEGAAGQLAIGATPTVSVDLLPSAISRFRERFPDAHLTLAEGTVEDMLPALREGRLDFVMGRTEVQGIDGELRCD
LLYPETIRVIAGPTHPLARKRKVGWADTRAYTWVGPPVTSQIRRELDYELALAGEPAPCVRIESATLLANVSLLQQGELL
AVMSGRMAAFFSRLGQVAILRLPYRREGMVGVLRRRDTEQTPLRQAFMDALAASAHG
>Mature_297_residues
MRIRQLHVLVALHETRNVSRTAARLNMTQPALSRWLAELESELGVALFERHSRGLVPTRFCEALVVHARTILNEIERTQA
TIRVMAEGAAGQLAIGATPTVSVDLLPSAISRFRERFPDAHLTLAEGTVEDMLPALREGRLDFVMGRTEVQGIDGELRCD
LLYPETIRVIAGPTHPLARKRKVGWADTRAYTWVGPPVTSQIRRELDYELALAGEPAPCVRIESATLLANVSLLQQGELL
AVMSGRMAAFFSRLGQVAILRLPYRREGMVGVLRRRDTEQTPLRQAFMDALAASAHG

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=287, Percent_Identity=29.9651567944251, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI87081904, Length=300, Percent_Identity=28, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790399, Length=145, Percent_Identity=39.3103448275862, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=25.9515570934256, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI157672245, Length=288, Percent_Identity=27.4305555555556, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787879, Length=188, Percent_Identity=29.7872340425532, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788887, Length=260, Percent_Identity=27.3076923076923, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789506, Length=145, Percent_Identity=27.5862068965517, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787530, Length=216, Percent_Identity=28.2407407407407, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788748, Length=219, Percent_Identity=26.9406392694064, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790262, Length=294, Percent_Identity=27.891156462585, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788297, Length=167, Percent_Identity=29.3413173652695, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788481, Length=208, Percent_Identity=27.8846153846154, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788296, Length=145, Percent_Identity=33.1034482758621, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI2367136, Length=140, Percent_Identity=31.4285714285714, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789204, Length=211, Percent_Identity=27.0142180094787, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1790208, Length=150, Percent_Identity=29.3333333333333, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32929; Mature: 32929

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIRQLHVLVALHETRNVSRTAARLNMTQPALSRWLAELESELGVALFERHSRGLVPTRF
CCHHHEEEEEEEHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
CEALVVHARTILNEIERTQATIRVMAEGAAGQLAIGATPTVSVDLLPSAISRFRERFPDA
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCCEEEHHHHHHHHHHHHHCCCC
HLTLAEGTVEDMLPALREGRLDFVMGRTEVQGIDGELRCDLLYPETIRVIAGPTHPLARK
EEEECCCCHHHHHHHHHCCCEEEEECCHHCCCCCCCEEEEEECCCEEEEEECCCCHHHHH
RKVGWADTRAYTWVGPPVTSQIRRELDYELALAGEPAPCVRIESATLLANVSLLQQGELL
CCCCCCCCCEEEEECCCHHHHHHHHCCCEEEECCCCCCEEEECCHHHHHHHHHHCCCCEE
AVMSGRMAAFFSRLGQVAILRLPYRREGMVGVLRRRDTEQTPLRQAFMDALAASAHG
EHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRIRQLHVLVALHETRNVSRTAARLNMTQPALSRWLAELESELGVALFERHSRGLVPTRF
CCHHHEEEEEEEHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
CEALVVHARTILNEIERTQATIRVMAEGAAGQLAIGATPTVSVDLLPSAISRFRERFPDA
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCCEEEHHHHHHHHHHHHHCCCC
HLTLAEGTVEDMLPALREGRLDFVMGRTEVQGIDGELRCDLLYPETIRVIAGPTHPLARK
EEEECCCCHHHHHHHHHCCCEEEEECCHHCCCCCCCEEEEEECCCEEEEEECCCCHHHHH
RKVGWADTRAYTWVGPPVTSQIRRELDYELALAGEPAPCVRIESATLLANVSLLQQGELL
CCCCCCCCCEEEEECCCHHHHHHHHCCCEEEECCCCCCEEEECCHHHHHHHHHHCCCCEE
AVMSGRMAAFFSRLGQVAILRLPYRREGMVGVLRRRDTEQTPLRQAFMDALAASAHG
EHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]