Click here to switch to the map view.

The map label for this gene is argE2 [H]

Identifier: 116694410

GI number: 116694410

Start: 517530

End: 518705

Strand: Direct

Name: argE2 [H]

Synonym: H16_B0459

Alternate gene names: 116694410

Gene position: 517530-518705 (Clockwise)

Preceding gene: 116694409

Following gene: 116694413

Centisome position: 17.77

GC content: 65.31

Gene sequence:

>1176_bases
ATGGAAAATCAAGCCTCCTCCGCAAGCGCCTCTCTCCTGGAAACGCTCGTTTCTTTCGCATCGGTTTCCCTGACGCCAAA
CATCGCGCTCATCCACAAGGTCCAGGACATCCTGGCGGAAGCCGGCATCGAATCGATGCTCGCGCCCGACCCGCAAGACC
CCAGCCGCTCCAATCTGTTTGCGACGGTCGGTCCGGTGGGCGTTCCGGGCGTCCTGCTCTCCGGCCATACCGATGTGGTG
CCGGTGGAAGGCCAGCCCTGGACTTCACCCCCGTTTGAGGCAACGCACCGGGATGGCCGCATCTACGGACGCGGCACAGC
CGACATGAAAGGCTTCGTGGCCTGCGCCGTCACCGCCATGGTGGCGGCCGCCCGGCAGCCGCTCCGGCGCCCCTTGCAGC
TGGCGCTGTCCTTCGATGAGGAAATCGGCTGCGTAGGTGTGCGCCACCTGCTGCGCCGCCTGGAGAACAGCCTCCCCGCA
CCCTACCTGTGCATTGTCGGCGAGCCGACCCTGATGCGGATCGGCACCGGTCACAAGGGCAAGGCTGCCTACCGGGCGGT
CTGCTGCGGCCAGGCCGGCCACTCAGGCCTGGCGCCCAGGTTCTTCAACGCCATCCACATGGCCAGCGACCTCGTCGCAT
CCCTGCGAGACGTGCAGCGTGAACTGGCGCAAAGCGGCCCGCGCGAGGAGGGCTACGGCGTGCCCTACAGCACGGTCCAC
GCCGGCGTCATCCACGGCGGCCGCGCCTTGAACATCGTGCCCAGCGAATGCGAAGTCAGCTTCGAGATTCGCAACGTCTC
GGAAGATAAACCCGAGCAGATCCTGAAGCGCGTCCTGGAACGCCTGGCCGAGCGCGTCAAAAAAGAGGCGCTGGATCCTG
CGGCGCCGTTGCCAGACATCCAGATGACGAACAGCTATCCCAGCCTGAACACCCGCGAGGATTCGCCTGCTGTCGGCCTG
CTCGCCTCGCTGCTCCCCGCGGGCACCCCATGCGCCAGGGTGGACTATGGCAGCGAGGGTGGATTGTTCCAGCAGAGCTG
GAATCAAACGCCAGTGCTGATCTGCGGGCCCGGGAGCATTGAAGTCGCACATAAGGCCGACGAGTATGTGGAGCTGGCGC
AGATCGAAGCCTGCGACCGCATGCTGGCCGGCCTCGTCGAATTTCTCTGTCGATAA

Upstream 100 bases:

>100_bases
TCGATCCCCATATAGCAGCGCCGCTGAAATCGGCGTCCTGAAGCGCCAGCCGCATCGGTCATGCCGTGTTTCGGCAATGC
CCCCTCAAGAAGGGCCAGAG

Downstream 100 bases:

>100_bases
GCCTGGCGTCCTGGCCAGCTTCGGCCCGGACGCCTCATAGACGCTATCAAAATGAAGTCAGCAGGATGCTGCGGTCGACC
GACTGGATATCCGTCTTGCC

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MENQASSASASLLETLVSFASVSLTPNIALIHKVQDILAEAGIESMLAPDPQDPSRSNLFATVGPVGVPGVLLSGHTDVV
PVEGQPWTSPPFEATHRDGRIYGRGTADMKGFVACAVTAMVAAARQPLRRPLQLALSFDEEIGCVGVRHLLRRLENSLPA
PYLCIVGEPTLMRIGTGHKGKAAYRAVCCGQAGHSGLAPRFFNAIHMASDLVASLRDVQRELAQSGPREEGYGVPYSTVH
AGVIHGGRALNIVPSECEVSFEIRNVSEDKPEQILKRVLERLAERVKKEALDPAAPLPDIQMTNSYPSLNTREDSPAVGL
LASLLPAGTPCARVDYGSEGGLFQQSWNQTPVLICGPGSIEVAHKADEYVELAQIEACDRMLAGLVEFLCR

Sequences:

>Translated_391_residues
MENQASSASASLLETLVSFASVSLTPNIALIHKVQDILAEAGIESMLAPDPQDPSRSNLFATVGPVGVPGVLLSGHTDVV
PVEGQPWTSPPFEATHRDGRIYGRGTADMKGFVACAVTAMVAAARQPLRRPLQLALSFDEEIGCVGVRHLLRRLENSLPA
PYLCIVGEPTLMRIGTGHKGKAAYRAVCCGQAGHSGLAPRFFNAIHMASDLVASLRDVQRELAQSGPREEGYGVPYSTVH
AGVIHGGRALNIVPSECEVSFEIRNVSEDKPEQILKRVLERLAERVKKEALDPAAPLPDIQMTNSYPSLNTREDSPAVGL
LASLLPAGTPCARVDYGSEGGLFQQSWNQTPVLICGPGSIEVAHKADEYVELAQIEACDRMLAGLVEFLCR
>Mature_391_residues
MENQASSASASLLETLVSFASVSLTPNIALIHKVQDILAEAGIESMLAPDPQDPSRSNLFATVGPVGVPGVLLSGHTDVV
PVEGQPWTSPPFEATHRDGRIYGRGTADMKGFVACAVTAMVAAARQPLRRPLQLALSFDEEIGCVGVRHLLRRLENSLPA
PYLCIVGEPTLMRIGTGHKGKAAYRAVCCGQAGHSGLAPRFFNAIHMASDLVASLRDVQRELAQSGPREEGYGVPYSTVH
AGVIHGGRALNIVPSECEVSFEIRNVSEDKPEQILKRVLERLAERVKKEALDPAAPLPDIQMTNSYPSLNTREDSPAVGL
LASLLPAGTPCARVDYGSEGGLFQQSWNQTPVLICGPGSIEVAHKADEYVELAQIEACDRMLAGLVEFLCR

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=392, Percent_Identity=31.1224489795918, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1788816, Length=235, Percent_Identity=30.6382978723404, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17551016, Length=342, Percent_Identity=28.0701754385965, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24649202, Length=350, Percent_Identity=26, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24649204, Length=350, Percent_Identity=26, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24649206, Length=319, Percent_Identity=26.9592476489028, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 41830; Mature: 41830

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENQASSASASLLETLVSFASVSLTPNIALIHKVQDILAEAGIESMLAPDPQDPSRSNLF
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCEE
ATVGPVGVPGVLLSGHTDVVPVEGQPWTSPPFEATHRDGRIYGRGTADMKGFVACAVTAM
EEECCCCCCCEEECCCCCEEECCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHH
VAAARQPLRRPLQLALSFDEEIGCVGVRHLLRRLENSLPAPYLCIVGEPTLMRIGTGHKG
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCC
KAAYRAVCCGQAGHSGLAPRFFNAIHMASDLVASLRDVQRELAQSGPREEGYGVPYSTVH
CHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AGVIHGGRALNIVPSECEVSFEIRNVSEDKPEQILKRVLERLAERVKKEALDPAAPLPDI
HHHHCCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
QMTNSYPSLNTREDSPAVGLLASLLPAGTPCARVDYGSEGGLFQQSWNQTPVLICGPGSI
EECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCCEEEECCCCE
EVAHKADEYVELAQIEACDRMLAGLVEFLCR
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENQASSASASLLETLVSFASVSLTPNIALIHKVQDILAEAGIESMLAPDPQDPSRSNLF
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCEE
ATVGPVGVPGVLLSGHTDVVPVEGQPWTSPPFEATHRDGRIYGRGTADMKGFVACAVTAM
EEECCCCCCCEEECCCCCEEECCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHH
VAAARQPLRRPLQLALSFDEEIGCVGVRHLLRRLENSLPAPYLCIVGEPTLMRIGTGHKG
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCC
KAAYRAVCCGQAGHSGLAPRFFNAIHMASDLVASLRDVQRELAQSGPREEGYGVPYSTVH
CHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AGVIHGGRALNIVPSECEVSFEIRNVSEDKPEQILKRVLERLAERVKKEALDPAAPLPDI
HHHHCCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
QMTNSYPSLNTREDSPAVGLLASLLPAGTPCARVDYGSEGGLFQQSWNQTPVLICGPGSI
EECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCCEEEECCCCE
EVAHKADEYVELAQIEACDRMLAGLVEFLCR
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA