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The map label for this gene is yvbU [H]

Identifier: 116694409

GI number: 116694409

Start: 516496

End: 517470

Strand: Direct

Name: yvbU [H]

Synonym: H16_B0458

Alternate gene names: 116694409

Gene position: 516496-517470 (Clockwise)

Preceding gene: 116694408

Following gene: 116694410

Centisome position: 17.73

GC content: 58.56

Gene sequence:

>975_bases
ATGCTCAATCGCATTTCCCTGCGCCAGATGGAGTATTTCGTCGCAACGGCGAAGCATGGCAGCATTGCCGCTGCGTCGAC
GCAAATCCATATCTCCTCTCCCTCGATCTCCGCAGCGATCGCCCATATCGAGGCCGAACTGGGCGTGCAGCTGTTCGTGC
GCCATTCTTCCAAGGGCATTGGCCTGACCACCATCGGCAAGCTGGTCCTGCATCACTGCGAAGATATGCTCGGACGGTCG
TCCCGACTCTATGAAATCGCCTCCGATTCGAGCGACGTCATCCAGGGCACCTTGCGGGTGGGAAGCTTCCAGTCGCTCAC
GGCAATGATTGCGCCCGAGGTCATCTTCGGCTTTTCGCGCGCGTTCAAGAAAATCGAGCTGCAGATGGTCGAAGGCGATC
AGGAAGTCTTGATGAACAAGCTCCATGCGCTTGAGATCGACGTGGCGATCACCTACGACCTGCACCTTGAGGACGACATC
CAGTTCGAGAGCCTGGCGACGATGCCGCCCTATGTCCTGGTGAGCGAGGTCCATCCGCTGGCGCAGCAGAAAGTCGTCTC
CTTCGAAGAGCTGGCGCCCGAACCCTACGTCCTGCTCGATATGCCGATGAGCCGGGACTATTTCACCTCCCTGTTTGAAA
AGGCCGGCGTGACGCCGAACATCGCGGCGCGTTCGCAGTCCACGGAAGTGGTCCGGTCCATGGTCGCCAACGGCATTGGC
TACGCACTCTTCAATGTGCGCCCCAAATCCGATCAATCGCTCGATGGAAAGCGCATGGTGCGGGTCCGCCTTGCCGGTAC
CCATCGGCCCATGCTGCTCGGCCTGGCGACTTACAAGCCGATGAAACAGTCAAGATTGACGAGAATCTTCATGGAACGCT
GCCGCGCTTATATCTCCGACCAATACATCCCCGGAATGAGCGCTCCAAGTTTCTTCGATCCCCATATAGCAGCGCCGCTG
AAATCGGCGTCCTGA

Upstream 100 bases:

>100_bases
CGCATCGAATGAAGCGTGACAGCGCCGGTCAGGCAGCCGGCACTCGAAAGGGCAAACCTTCTCCAGTACACTGGATCGTT
CCCCTTTTCCTGATCTCGAC

Downstream 100 bases:

>100_bases
AGCGCCAGCCGCATCGGTCATGCCGTGTTTCGGCAATGCCCCCTCAAGAAGGGCCAGAGATGGAAAATCAAGCCTCCTCC
GCAAGCGCCTCTCTCCTGGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MLNRISLRQMEYFVATAKHGSIAAASTQIHISSPSISAAIAHIEAELGVQLFVRHSSKGIGLTTIGKLVLHHCEDMLGRS
SRLYEIASDSSDVIQGTLRVGSFQSLTAMIAPEVIFGFSRAFKKIELQMVEGDQEVLMNKLHALEIDVAITYDLHLEDDI
QFESLATMPPYVLVSEVHPLAQQKVVSFEELAPEPYVLLDMPMSRDYFTSLFEKAGVTPNIAARSQSTEVVRSMVANGIG
YALFNVRPKSDQSLDGKRMVRVRLAGTHRPMLLGLATYKPMKQSRLTRIFMERCRAYISDQYIPGMSAPSFFDPHIAAPL
KSAS

Sequences:

>Translated_324_residues
MLNRISLRQMEYFVATAKHGSIAAASTQIHISSPSISAAIAHIEAELGVQLFVRHSSKGIGLTTIGKLVLHHCEDMLGRS
SRLYEIASDSSDVIQGTLRVGSFQSLTAMIAPEVIFGFSRAFKKIELQMVEGDQEVLMNKLHALEIDVAITYDLHLEDDI
QFESLATMPPYVLVSEVHPLAQQKVVSFEELAPEPYVLLDMPMSRDYFTSLFEKAGVTPNIAARSQSTEVVRSMVANGIG
YALFNVRPKSDQSLDGKRMVRVRLAGTHRPMLLGLATYKPMKQSRLTRIFMERCRAYISDQYIPGMSAPSFFDPHIAAPL
KSAS
>Mature_324_residues
MLNRISLRQMEYFVATAKHGSIAAASTQIHISSPSISAAIAHIEAELGVQLFVRHSSKGIGLTTIGKLVLHHCEDMLGRS
SRLYEIASDSSDVIQGTLRVGSFQSLTAMIAPEVIFGFSRAFKKIELQMVEGDQEVLMNKLHALEIDVAITYDLHLEDDI
QFESLATMPPYVLVSEVHPLAQQKVVSFEELAPEPYVLLDMPMSRDYFTSLFEKAGVTPNIAARSQSTEVVRSMVANGIG
YALFNVRPKSDQSLDGKRMVRVRLAGTHRPMLLGLATYKPMKQSRLTRIFMERCRAYISDQYIPGMSAPSFFDPHIAAPL
KSAS

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=241, Percent_Identity=28.2157676348548, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787530, Length=261, Percent_Identity=26.0536398467433, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI157672245, Length=229, Percent_Identity=28.82096069869, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788296, Length=246, Percent_Identity=24.390243902439, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787879, Length=252, Percent_Identity=25, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789204, Length=262, Percent_Identity=23.6641221374046, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787601, Length=243, Percent_Identity=23.8683127572016, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788748, Length=240, Percent_Identity=24.1666666666667, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87081904, Length=190, Percent_Identity=30, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788481, Length=249, Percent_Identity=23.2931726907631, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367136, Length=249, Percent_Identity=26.5060240963855, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787806, Length=246, Percent_Identity=26.0162601626016, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790262, Length=240, Percent_Identity=23.3333333333333, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI145693105, Length=217, Percent_Identity=22.5806451612903, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788706, Length=153, Percent_Identity=31.3725490196078, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788887, Length=254, Percent_Identity=25.5905511811024, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35905; Mature: 35905

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNRISLRQMEYFVATAKHGSIAAASTQIHISSPSISAAIAHIEAELGVQLFVRHSSKGI
CCCCHHHHHHHHHHEECCCCCEEEEEEEEEEECCCHHHHHHHHHHHCCEEEEEEECCCCC
GLTTIGKLVLHHCEDMLGRSSRLYEIASDSSDVIQGTLRVGSFQSLTAMIAPEVIFGFSR
CHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AFKKIELQMVEGDQEVLMNKLHALEIDVAITYDLHLEDDIQFESLATMPPYVLVSEVHPL
HHHHEEEEEECCCHHHHHHHHHHEEEEEEEEEEEEECCCCCHHHHCCCCCEEEHHHHCHH
AQQKVVSFEELAPEPYVLLDMPMSRDYFTSLFEKAGVTPNIAARSQSTEVVRSMVANGIG
HHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
YALFNVRPKSDQSLDGKRMVRVRLAGTHRPMLLGLATYKPMKQSRLTRIFMERCRAYISD
EEEEECCCCCCCCCCCCEEEEEEECCCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHHCC
QYIPGMSAPSFFDPHIAAPLKSAS
CCCCCCCCCCCCCCHHCCCCCCCC
>Mature Secondary Structure
MLNRISLRQMEYFVATAKHGSIAAASTQIHISSPSISAAIAHIEAELGVQLFVRHSSKGI
CCCCHHHHHHHHHHEECCCCCEEEEEEEEEEECCCHHHHHHHHHHHCCEEEEEEECCCCC
GLTTIGKLVLHHCEDMLGRSSRLYEIASDSSDVIQGTLRVGSFQSLTAMIAPEVIFGFSR
CHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AFKKIELQMVEGDQEVLMNKLHALEIDVAITYDLHLEDDIQFESLATMPPYVLVSEVHPL
HHHHEEEEEECCCHHHHHHHHHHEEEEEEEEEEEEECCCCCHHHHCCCCCEEEHHHHCHH
AQQKVVSFEELAPEPYVLLDMPMSRDYFTSLFEKAGVTPNIAARSQSTEVVRSMVANGIG
HHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
YALFNVRPKSDQSLDGKRMVRVRLAGTHRPMLLGLATYKPMKQSRLTRIFMERCRAYISD
EEEEECCCCCCCCCCCCEEEEEEECCCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHHCC
QYIPGMSAPSFFDPHIAAPLKSAS
CCCCCCCCCCCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]