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The map label for this gene is pknK [H]

Identifier: 116694327

GI number: 116694327

Start: 421836

End: 423602

Strand: Direct

Name: pknK [H]

Synonym: H16_B0373

Alternate gene names: 116694327

Gene position: 421836-423602 (Clockwise)

Preceding gene: 116694326

Following gene: 116694328

Centisome position: 14.48

GC content: 70.29

Gene sequence:

>1767_bases
ATGCGTAGCGCTCCCCCGATCGTTCTGACCGAGCAGGATCGTACCCGGCTCGAAGCGCTCGCTGCGGCGGCGGATGCACC
GGCCAGGGTGGCGCAGCGCGCGCGCATCATCCTGCTGGCCGCGGCGGGAGTACAGAACCAGGCGATTGCCCCGCGCCTCG
GCATCGGGCGGGCCCAGGTGGCACGCTGGCGCGAGCGCTATGTGCAAGCCGGGCTGGCCGGCATCCTCAACGACCTGCCG
CGCGGCGCGCCGCCGGTCAAGGTGGACGTGGCGCGCATGGCGGTGCTGACGGGCACGGATGGCAACGGGCAGCCCCGGGC
CTGGGGCGTGCAAAGCCTGGCCACCGAGCTGGGGGTCAGTCCGGCAAGCGTCTCGCGCCACCGGCGTGCCGCGGGACTTG
TCTCCGGCAATATGCGCAGGACTGGCTATCTCCCCCCCGCGCCGTTCACCGGTGGCATGGCCGAGATCGTTGCCCTGTAC
GTGTCGGCGCCGGAGCATGCGCTGGTCCTGGCGTTCGATGGAGGCGAGGACCAGGACAGCAATGCCGGCGCCCTGCCTCG
CATGTGCCCGGCGCCGGCACAGCAGCGCAGCCTGACCGCATCGCTGCTGACCGCATCGCTGCTGACCGCACTCAGGGTAC
TCGACGGCGAACTTGCGCAGGCGCCTTCCGGGTCCGGCCGGCACAGGCAGTGGCTTGCCTTCCTGCAGGAGGTCGATGCG
GCCACCGTGCCCGGCCGCAGCCTTTGGGTTTTTGCGGACAACCATGCGTGCCACCAGCACGCCGAAGTGCAGCAATGGCT
GGAGCGCCATCCGCGCATCACCGTCCAGCTGGCACCCAGTGCGGCAAGCTGGCTGCGCACGGTCCAGGGGTTCCTGCGGG
AGTCCCGGGCCGGCCAGGCGGCCTGCCGGACGAGATTTCCGTCCGGCATTCCGGAGGCGCTGGCGGCGATCGAGGCCGCC
AGGCGCTCGCGCGGCGCCGTGCCCTACCGATGGATACGCGAGCGCGCCGCGGCGCGGGTGACAGACGCCCGGACCCCTTC
GGGGGCACGGCGGCCTGTGCTGCCGGTCGTCGGCACGAAGGTACTGCCGCCGCACGGCACCGGCCAGCTGATGCCGCGCG
AAGCCCTGATGGCCCGCCTCATGCAGTCGCGCCGGCACCGTTGCGTGGTCATCCAGGGTCAGGCGGGAAGCGGCAAGACC
AGCGTGCTGGTGGCCTGGCGCAAGGCGATGATCTCCTTCGGCTATGACGTCTGCTGGCTGTCGCTGTCCGTGGAGGACAA
CGATCCTGCGCGCTTCCTCGACTACCTGTTTGCCAGCATTGCCGAGTCCGCCCCCACCGTAGCGGGCAAGGTTCAGGAGG
TGGGGGCCGGACACGACGGCGAGACGCTGGAACTGCGGATCATTGCGCTGGTACAGGAGCTTTCCCGGCGCACGCGCGAC
CTGGTGCTGATGATCGACGACCTGCACCACGTGTCCGATTCGCGCATCCTGCGCGCGCTGCAGTTGCTGCTTGACTACGC
CCCGCCGCAACTGCACGTGGCGGTGGCTTCCCGCACCGCGCTGGAACTGTCCATGGAGCGACTGCGACTGCAGAACCTGC
TGGCGGAATTCGACATGCGCGACCTGCGCTTTTCGCCCGAGGAGTCGGCCCGCTTCCTGCTTGACCGCCTGGGCAGCATC
ACGCCCGCCGACGCGGCAGCCATGCACGAACTGACCGACGGATGGGTGGCCGGCCTGCAACTGCTGGCAATCGGGCTGCG
CAAGTAG

Upstream 100 bases:

>100_bases
GCCGGACAACTGGGCTGAGCGCTGCGCGATCGCGTGATTTCCGGTCAGGGCCCCGGCGCAGTCACGGCCGGGGCTGTCCC
TTTGCTCGCCCAGGCTCGAC

Downstream 100 bases:

>100_bases
CGGCCCGGCAGCTACCCTGTGGCGCAACTCCGCGATCCCCGCGCGTTCGCGAGCTACTTCGAGCGTGAAGTGCTGGTCCG
GCTGGCTCCGGACGATCTCG

Product: transposase or inactivated derivative

Products: NA

Alternate protein names: Protein kinase K [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MRSAPPIVLTEQDRTRLEALAAAADAPARVAQRARIILLAAAGVQNQAIAPRLGIGRAQVARWRERYVQAGLAGILNDLP
RGAPPVKVDVARMAVLTGTDGNGQPRAWGVQSLATELGVSPASVSRHRRAAGLVSGNMRRTGYLPPAPFTGGMAEIVALY
VSAPEHALVLAFDGGEDQDSNAGALPRMCPAPAQQRSLTASLLTASLLTALRVLDGELAQAPSGSGRHRQWLAFLQEVDA
ATVPGRSLWVFADNHACHQHAEVQQWLERHPRITVQLAPSAASWLRTVQGFLRESRAGQAACRTRFPSGIPEALAAIEAA
RRSRGAVPYRWIRERAAARVTDARTPSGARRPVLPVVGTKVLPPHGTGQLMPREALMARLMQSRRHRCVVIQGQAGSGKT
SVLVAWRKAMISFGYDVCWLSLSVEDNDPARFLDYLFASIAESAPTVAGKVQEVGAGHDGETLELRIIALVQELSRRTRD
LVLMIDDLHHVSDSRILRALQLLLDYAPPQLHVAVASRTALELSMERLRLQNLLAEFDMRDLRFSPEESARFLLDRLGSI
TPADAAAMHELTDGWVAGLQLLAIGLRK

Sequences:

>Translated_588_residues
MRSAPPIVLTEQDRTRLEALAAAADAPARVAQRARIILLAAAGVQNQAIAPRLGIGRAQVARWRERYVQAGLAGILNDLP
RGAPPVKVDVARMAVLTGTDGNGQPRAWGVQSLATELGVSPASVSRHRRAAGLVSGNMRRTGYLPPAPFTGGMAEIVALY
VSAPEHALVLAFDGGEDQDSNAGALPRMCPAPAQQRSLTASLLTASLLTALRVLDGELAQAPSGSGRHRQWLAFLQEVDA
ATVPGRSLWVFADNHACHQHAEVQQWLERHPRITVQLAPSAASWLRTVQGFLRESRAGQAACRTRFPSGIPEALAAIEAA
RRSRGAVPYRWIRERAAARVTDARTPSGARRPVLPVVGTKVLPPHGTGQLMPREALMARLMQSRRHRCVVIQGQAGSGKT
SVLVAWRKAMISFGYDVCWLSLSVEDNDPARFLDYLFASIAESAPTVAGKVQEVGAGHDGETLELRIIALVQELSRRTRD
LVLMIDDLHHVSDSRILRALQLLLDYAPPQLHVAVASRTALELSMERLRLQNLLAEFDMRDLRFSPEESARFLLDRLGSI
TPADAAAMHELTDGWVAGLQLLAIGLRK
>Mature_588_residues
MRSAPPIVLTEQDRTRLEALAAAADAPARVAQRARIILLAAAGVQNQAIAPRLGIGRAQVARWRERYVQAGLAGILNDLP
RGAPPVKVDVARMAVLTGTDGNGQPRAWGVQSLATELGVSPASVSRHRRAAGLVSGNMRRTGYLPPAPFTGGMAEIVALY
VSAPEHALVLAFDGGEDQDSNAGALPRMCPAPAQQRSLTASLLTASLLTALRVLDGELAQAPSGSGRHRQWLAFLQEVDA
ATVPGRSLWVFADNHACHQHAEVQQWLERHPRITVQLAPSAASWLRTVQGFLRESRAGQAACRTRFPSGIPEALAAIEAA
RRSRGAVPYRWIRERAAARVTDARTPSGARRPVLPVVGTKVLPPHGTGQLMPREALMARLMQSRRHRCVVIQGQAGSGKT
SVLVAWRKAMISFGYDVCWLSLSVEDNDPARFLDYLFASIAESAPTVAGKVQEVGAGHDGETLELRIIALVQELSRRTRD
LVLMIDDLHHVSDSRILRALQLLLDYAPPQLHVAVASRTALELSMERLRLQNLLAEFDMRDLRFSPEESARFLLDRLGSI
TPADAAAMHELTDGWVAGLQLLAIGLRK

Specific function: Modulates the activity of transcription regulator virS via phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane. Note=Probably attached to cell membrane through interactions mediated by its C- terminal region (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Escherichia coli, GI2367223, Length=234, Percent_Identity=26.9230769230769, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR016236
- InterPro:   IPR011990 [H]

Pfam domain/function: PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 63703; Mature: 63703

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSAPPIVLTEQDRTRLEALAAAADAPARVAQRARIILLAAAGVQNQAIAPRLGIGRAQV
CCCCCCEEEECCHHHHHHHHHHHCCCHHHHHHHCEEEEEEECCCCCCCCCCCCCCCHHHH
ARWRERYVQAGLAGILNDLPRGAPPVKVDVARMAVLTGTDGNGQPRAWGVQSLATELGVS
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHEEEEECCCCCCCCCHHHHHHHHHHHCCC
PASVSRHRRAAGLVSGNMRRTGYLPPAPFTGGMAEIVALYVSAPEHALVLAFDGGEDQDS
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCC
NAGALPRMCPAPAQQRSLTASLLTASLLTALRVLDGELAQAPSGSGRHRQWLAFLQEVDA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHCC
ATVPGRSLWVFADNHACHQHAEVQQWLERHPRITVQLAPSAASWLRTVQGFLRESRAGQA
CCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCHH
ACRTRFPSGIPEALAAIEAARRSRGAVPYRWIRERAAARVTDARTPSGARRPVLPVVGTK
HHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCC
VLPPHGTGQLMPREALMARLMQSRRHRCVVIQGQAGSGKTSVLVAWRKAMISFGYDVCWL
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEE
SLSVEDNDPARFLDYLFASIAESAPTVAGKVQEVGAGHDGETLELRIIALVQELSRRTRD
EEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHE
LVLMIDDLHHVSDSRILRALQLLLDYAPPQLHVAVASRTALELSMERLRLQNLLAEFDMR
EEEEEHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCHH
DLRFSPEESARFLLDRLGSITPADAAAMHELTDGWVAGLQLLAIGLRK
HCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRSAPPIVLTEQDRTRLEALAAAADAPARVAQRARIILLAAAGVQNQAIAPRLGIGRAQV
CCCCCCEEEECCHHHHHHHHHHHCCCHHHHHHHCEEEEEEECCCCCCCCCCCCCCCHHHH
ARWRERYVQAGLAGILNDLPRGAPPVKVDVARMAVLTGTDGNGQPRAWGVQSLATELGVS
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHEEEEECCCCCCCCCHHHHHHHHHHHCCC
PASVSRHRRAAGLVSGNMRRTGYLPPAPFTGGMAEIVALYVSAPEHALVLAFDGGEDQDS
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCC
NAGALPRMCPAPAQQRSLTASLLTASLLTALRVLDGELAQAPSGSGRHRQWLAFLQEVDA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHCC
ATVPGRSLWVFADNHACHQHAEVQQWLERHPRITVQLAPSAASWLRTVQGFLRESRAGQA
CCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCHH
ACRTRFPSGIPEALAAIEAARRSRGAVPYRWIRERAAARVTDARTPSGARRPVLPVVGTK
HHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCC
VLPPHGTGQLMPREALMARLMQSRRHRCVVIQGQAGSGKTSVLVAWRKAMISFGYDVCWL
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEE
SLSVEDNDPARFLDYLFASIAESAPTVAGKVQEVGAGHDGETLELRIIALVQELSRRTRD
EEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHE
LVLMIDDLHHVSDSRILRALQLLLDYAPPQLHVAVASRTALELSMERLRLQNLLAEFDMR
EEEEEHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCHH
DLRFSPEESARFLLDRLGSITPADAAAMHELTDGWVAGLQLLAIGLRK
HCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]