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The map label for this gene is flhA [H]

Identifier: 116694208

GI number: 116694208

Start: 289041

End: 291122

Strand: Direct

Name: flhA [H]

Synonym: H16_B0253

Alternate gene names: 116694208

Gene position: 289041-291122 (Clockwise)

Preceding gene: 116694207

Following gene: 116694209

Centisome position: 9.92

GC content: 67.24

Gene sequence:

>2082_bases
ATGAACGCTCTGAGCAACCTGTTCAACCTGCCCGGCCTGCGCTCCGCCGGCCAGCTCAAGGCCATGACCGGGCCGCTGCT
GATCATCATGATCCTGGGGATGATGATCCTGCCGCTGCCGGCCTTCGTGCTGGACCTGCTGTTCACCTTCAATATCGCGC
TGGCGATCATGGTGCTGCTGGTCAGCATGTACACGCAGAAGCCGCTGGACTTTGCCGCCTTCCCGGCGGTGCTGCTGTTC
ACCACGCTGCTGCGCCTGTCGCTGAACGTGGCCTCCACGCGCGTGGTGCTGCTCGAAGGCCATACCGGCCCGGACGCCGC
GGGCAAGGTGGTGGAGGCCTTCGGCCACTTCCTGGTAGGGGGCAACTTCGCGGTCGGCATCGTGGTGTTCGCGATCCTGG
TGGTGATCAACTTCATGGTGATCACCAAGGGTGCGGGGCGTATCGCCGAAGTCGGCGCGCGCTTCATGCTGGATTCGATG
CCCGGCAAGCAGATGTCGATCGATGCCGACCTGAACGCCGGCCTGATCGACGAGGCCGCCGCCAAGAAGCGCCGCGCCGA
AGTGGCGCAGGAATCCGACTTCTACGGCGCGATGGACGGCGCCAGCAAGTTCGTGCGCGGCGATGCCGTGGCGGGCCTGC
TGATCATGTTCATCAACGTTGCCGCCGGCATGGTGGTGGGCATGGTGCAGCACGACCTGGACTTCGGCACCGCCGTGCAC
AACTACACGCTGCTGACCATCGGCGACGGCCTGGTGGCGCAGATCCCGGCGCTGGTGATCTCCACCGCCGCCGGCGTGAT
CGTGTCGCGCGTGTCGAACGAGCAGGACGTGGGCGAGCAGCTCACCGGCCAGCTCTTTGCCAACCCGCGCGTGCTGTACC
TGACCGCGGGCATCATCGGCCTGATGGGCATCATCCCGGGCATGCCGCATTTTGCCTTCCTGCTGCTGGCGGGCGCGCTG
GTGTGGATGGGCCGTTATATGTCGCGCCGCGCCGCCACGCAGGAGCAGGTCAAGCAGCGCGAGGAGCGCACCCCGGCGGT
GGCGCAGGAATCCACTGAAGCGAGCTGGGACGACGTCACGCTGGTCGACCCGCTCGGCATGGAAGTGGGCTACCGCCTGA
TCACGCTGGTGGACCGCGCGCAGGACGGCGAGCTGCTGGGCCGCATCAAGAGCATCCGCAAGAAGGTGGCGCAGGAGATC
GGTTTCCTGGTGCCGGTGGTGCATATCCGCGACAACCTGGAGCTCAAGCCCAACGCCTACCGCATCACGCTCAAGGGCGT
GGAGATCGGCCGCGGCGAAGCCATGCCGGGCCAGTGGATGGCGATCAACCCCGGGCAGGTCAGCGGCACGCTGCCTGGCG
CGGCCACGCGCGATCCTGCCTTCGGCCTGCCGGCGGTATGGATCGACGCGGGCATCAAGGAGCAGGCGCAGTCCTACGGC
TATACCGTGGTCGATGCCAGCACCGTGGTGGCCACGCACCTGAACCACCTGATCCACATGCACGCCGCCGAGCTGCTAGG
CCGCCAGGAAGTGCAGGCGCTGCTGGACCGCATCGCCAAGGACTCGCCCAAGCTGACCGAAGACCTGGTGCCGAAGGCCA
TTTCGCTGACCGCGCTGCAGAAGATCCTGCAGAACCTGCTGGACGAAGGCGTTCCCATCCGCGACATGCGCACCATCCTG
GATGTGGTGGCCGAGCATGCGCCCAAGATCAGCGACCCGAACGAGCTGACCGCGATGGTGCGCGTGGCGCTGGGCCGCGC
GATCACGCAGCAGCTGTTCCCGAACAACGCCGACCTGCAGGTGATCGGCCTCGATGCCGGCCTGGAGCGCGTGCTGTCGC
AGGCGCTGACCAATGGCGGCGGGATCGAGCCGGGCCTGGCCGATGCGTTGCTGCAGCAGACCCAGGGCGCGGTCACGCGC
CAGGAGCAGCTGGGCATGGACCCGGTGCTGCTGGTGCCGTCGCAGCTGCGCCCGCTGATGGCGCGCTTCCTGCGGCGCAC
CATGCCGCAGCTGAGGGTGCTGTCGCATGCCGAGGTGCCGGACAACCGCAATATCCGCATCACCGCCATGATCGGCGCGT
GA

Upstream 100 bases:

>100_bases
TCTATCAACTGAAGCACTGGCATTACTCGCAGGGCCCGCAGCCGCAGGCACCCGCGGACCTGCCGGTGCCCGATGAACTC
GCCGTACCGGAAATGCGCGA

Downstream 100 bases:

>100_bases
GGAGTCATAGATGAGCGTAGCCAAGTTTGTCGCGGCCAACGGCCGCGAAGCCATGCGCCAGGTGCGCGAAGCCATGGGCC
CGGACGCCGTGGTGCTGTCC

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MNALSNLFNLPGLRSAGQLKAMTGPLLIIMILGMMILPLPAFVLDLLFTFNIALAIMVLLVSMYTQKPLDFAAFPAVLLF
TTLLRLSLNVASTRVVLLEGHTGPDAAGKVVEAFGHFLVGGNFAVGIVVFAILVVINFMVITKGAGRIAEVGARFMLDSM
PGKQMSIDADLNAGLIDEAAAKKRRAEVAQESDFYGAMDGASKFVRGDAVAGLLIMFINVAAGMVVGMVQHDLDFGTAVH
NYTLLTIGDGLVAQIPALVISTAAGVIVSRVSNEQDVGEQLTGQLFANPRVLYLTAGIIGLMGIIPGMPHFAFLLLAGAL
VWMGRYMSRRAATQEQVKQREERTPAVAQESTEASWDDVTLVDPLGMEVGYRLITLVDRAQDGELLGRIKSIRKKVAQEI
GFLVPVVHIRDNLELKPNAYRITLKGVEIGRGEAMPGQWMAINPGQVSGTLPGAATRDPAFGLPAVWIDAGIKEQAQSYG
YTVVDASTVVATHLNHLIHMHAAELLGRQEVQALLDRIAKDSPKLTEDLVPKAISLTALQKILQNLLDEGVPIRDMRTIL
DVVAEHAPKISDPNELTAMVRVALGRAITQQLFPNNADLQVIGLDAGLERVLSQALTNGGGIEPGLADALLQQTQGAVTR
QEQLGMDPVLLVPSQLRPLMARFLRRTMPQLRVLSHAEVPDNRNIRITAMIGA

Sequences:

>Translated_693_residues
MNALSNLFNLPGLRSAGQLKAMTGPLLIIMILGMMILPLPAFVLDLLFTFNIALAIMVLLVSMYTQKPLDFAAFPAVLLF
TTLLRLSLNVASTRVVLLEGHTGPDAAGKVVEAFGHFLVGGNFAVGIVVFAILVVINFMVITKGAGRIAEVGARFMLDSM
PGKQMSIDADLNAGLIDEAAAKKRRAEVAQESDFYGAMDGASKFVRGDAVAGLLIMFINVAAGMVVGMVQHDLDFGTAVH
NYTLLTIGDGLVAQIPALVISTAAGVIVSRVSNEQDVGEQLTGQLFANPRVLYLTAGIIGLMGIIPGMPHFAFLLLAGAL
VWMGRYMSRRAATQEQVKQREERTPAVAQESTEASWDDVTLVDPLGMEVGYRLITLVDRAQDGELLGRIKSIRKKVAQEI
GFLVPVVHIRDNLELKPNAYRITLKGVEIGRGEAMPGQWMAINPGQVSGTLPGAATRDPAFGLPAVWIDAGIKEQAQSYG
YTVVDASTVVATHLNHLIHMHAAELLGRQEVQALLDRIAKDSPKLTEDLVPKAISLTALQKILQNLLDEGVPIRDMRTIL
DVVAEHAPKISDPNELTAMVRVALGRAITQQLFPNNADLQVIGLDAGLERVLSQALTNGGGIEPGLADALLQQTQGAVTR
QEQLGMDPVLLVPSQLRPLMARFLRRTMPQLRVLSHAEVPDNRNIRITAMIGA
>Mature_693_residues
MNALSNLFNLPGLRSAGQLKAMTGPLLIIMILGMMILPLPAFVLDLLFTFNIALAIMVLLVSMYTQKPLDFAAFPAVLLF
TTLLRLSLNVASTRVVLLEGHTGPDAAGKVVEAFGHFLVGGNFAVGIVVFAILVVINFMVITKGAGRIAEVGARFMLDSM
PGKQMSIDADLNAGLIDEAAAKKRRAEVAQESDFYGAMDGASKFVRGDAVAGLLIMFINVAAGMVVGMVQHDLDFGTAVH
NYTLLTIGDGLVAQIPALVISTAAGVIVSRVSNEQDVGEQLTGQLFANPRVLYLTAGIIGLMGIIPGMPHFAFLLLAGAL
VWMGRYMSRRAATQEQVKQREERTPAVAQESTEASWDDVTLVDPLGMEVGYRLITLVDRAQDGELLGRIKSIRKKVAQEI
GFLVPVVHIRDNLELKPNAYRITLKGVEIGRGEAMPGQWMAINPGQVSGTLPGAATRDPAFGLPAVWIDAGIKEQAQSYG
YTVVDASTVVATHLNHLIHMHAAELLGRQEVQALLDRIAKDSPKLTEDLVPKAISLTALQKILQNLLDEGVPIRDMRTIL
DVVAEHAPKISDPNELTAMVRVALGRAITQQLFPNNADLQVIGLDAGLERVLSQALTNGGGIEPGLADALLQQTQGAVTR
QEQLGMDPVLLVPSQLRPLMARFLRRTMPQLRVLSHAEVPDNRNIRITAMIGA

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=694, Percent_Identity=68.1556195965418, Blast_Score=932, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74531; Mature: 74531

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALSNLFNLPGLRSAGQLKAMTGPLLIIMILGMMILPLPAFVLDLLFTFNIALAIMVLL
CCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSMYTQKPLDFAAFPAVLLFTTLLRLSLNVASTRVVLLEGHTGPDAAGKVVEAFGHFLVG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHCC
GNFAVGIVVFAILVVINFMVITKGAGRIAEVGARFMLDSMPGKQMSIDADLNAGLIDEAA
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHH
AKKRRAEVAQESDFYGAMDGASKFVRGDAVAGLLIMFINVAAGMVVGMVQHDLDFGTAVH
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCHHHH
NYTLLTIGDGLVAQIPALVISTAAGVIVSRVSNEQDVGEQLTGQLFANPRVLYLTAGIIG
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEHHHHHHH
LMGIIPGMPHFAFLLLAGALVWMGRYMSRRAATQEQVKQREERTPAVAQESTEASWDDVT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCEE
LVDPLGMEVGYRLITLVDRAQDGELLGRIKSIRKKVAQEIGFLVPVVHIRDNLELKPNAY
EECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEECCCEE
RITLKGVEIGRGEAMPGQWMAINPGQVSGTLPGAATRDPAFGLPAVWIDAGIKEQAQSYG
EEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHCC
YTVVDASTVVATHLNHLIHMHAAELLGRQEVQALLDRIAKDSPKLTEDLVPKAISLTALQ
EEEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
KILQNLLDEGVPIRDMRTILDVVAEHAPKISDPNELTAMVRVALGRAITQQLFPNNADLQ
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VIGLDAGLERVLSQALTNGGGIEPGLADALLQQTQGAVTRQEQLGMDPVLLVPSQLRPLM
EEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHCCCCCEEECCHHHHHHH
ARFLRRTMPQLRVLSHAEVPDNRNIRITAMIGA
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MNALSNLFNLPGLRSAGQLKAMTGPLLIIMILGMMILPLPAFVLDLLFTFNIALAIMVLL
CCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSMYTQKPLDFAAFPAVLLFTTLLRLSLNVASTRVVLLEGHTGPDAAGKVVEAFGHFLVG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHCC
GNFAVGIVVFAILVVINFMVITKGAGRIAEVGARFMLDSMPGKQMSIDADLNAGLIDEAA
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHH
AKKRRAEVAQESDFYGAMDGASKFVRGDAVAGLLIMFINVAAGMVVGMVQHDLDFGTAVH
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCHHHH
NYTLLTIGDGLVAQIPALVISTAAGVIVSRVSNEQDVGEQLTGQLFANPRVLYLTAGIIG
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEHHHHHHH
LMGIIPGMPHFAFLLLAGALVWMGRYMSRRAATQEQVKQREERTPAVAQESTEASWDDVT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCEE
LVDPLGMEVGYRLITLVDRAQDGELLGRIKSIRKKVAQEIGFLVPVVHIRDNLELKPNAY
EECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEECCCEE
RITLKGVEIGRGEAMPGQWMAINPGQVSGTLPGAATRDPAFGLPAVWIDAGIKEQAQSYG
EEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHCC
YTVVDASTVVATHLNHLIHMHAAELLGRQEVQALLDRIAKDSPKLTEDLVPKAISLTALQ
EEEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
KILQNLLDEGVPIRDMRTILDVVAEHAPKISDPNELTAMVRVALGRAITQQLFPNNADLQ
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VIGLDAGLERVLSQALTNGGGIEPGLADALLQQTQGAVTRQEQLGMDPVLLVPSQLRPLM
EEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHCCCCCEEECCHHHHHHH
ARFLRRTMPQLRVLSHAEVPDNRNIRITAMIGA
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]