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The map label for this gene is yhdG [H]

Identifier: 116691074

GI number: 116691074

Start: 3370416

End: 3371822

Strand: Direct

Name: yhdG [H]

Synonym: Bcen2424_3056

Alternate gene names: 116691074

Gene position: 3370416-3371822 (Clockwise)

Preceding gene: 116691073

Following gene: 116691075

Centisome position: 96.74

GC content: 67.38

Gene sequence:

>1407_bases
ATGTCTCTCTTCCGCAAGAAAAACGTCGATCGCATGATCGCCGGCGCGCAAGCCGCCGGGCTCAAGAAAGCGCTCGGCGC
GATCGACCTCACCTTCCTCGGCATCGGCGCGATCATCGGCACCGGCATCTTCGTGCTGACCGGCACCGGCGCCGTCCAGG
CCGGCCCCGCGCTGATGCTGTCGTTCGTGATCGCCGCGATCGCGTGCGGCCTGGCCGCGCTGTCGTACGCGGAGTTCGCG
TCGTCGATCCCCGTCGCCGGCTCGATCTACACGTATTCGTACGCGACGCTCGGCGAGCTGGTCGCGTGGATCATCGGCTG
GGACCTGATGCTCGAGTACGGCCTCGCATCGTCGGCCGTGTCGGTCGGCTGGTCGGGCTACCTGCAGTCGCTGCTGCAGG
GCTTCGGGCTCACGCTGCCGACCGTGCTGACGGCCGCGCCCGGCGCGGTGCCCGGCGTCACCACGTGGTTCAACCTGCCC
GCGTTCCTCGTGATGATCGTAATCACGACGCTGCTGTCGATCGGCATCCGCGAATCGACCCGCATCAACAACATCATGGT
GTTCATCAAGGTGTCGGTCGTGCTGCTGGTGATCGCGGTCGGCCTGTTCCACGTGACGCCCGCGAACTGGAAGCCGTTCA
TGCCGCACGGCTGGAACGGCGTGTTCGGCGCGGCCGCCGTGATGTTCTTCGCGTTCATCGGCTTCGATGCGGTGTCGTCG
GCGGCCGAGGAAGTGAAGAATCCGAAGCGCGATCTGCCGATCGGCATCATCGCGTCGCTCGCGGTATGCGCGGTGCTGTA
CGTGACGGTCGCCGCGGTCGCCACCGGCATCGTGCCGTCGGCCCAGTACGCGAACATCTCGCACCCGATCTCGTACGCGC
TGCAGGTCGCCGGCGAGAAGTGGGTCGCGGGCTTCATCGATCTCGGCGCGGTGCTCGGCATGCTGACCGTGATCCTCGTG
ATGAGCTACGGCCAGACGCGCGTGATCTTCGCGATGTCGCGCGACGGGCTGCTGCCGGCCGCGCTGTCGCGCGTGCATCC
GCGTTATGCGACGCCGTTCCTGACCACCTGGCTGGTCGGCCTGTTCTTCGGGCTGATCGCCGCGCTCGTGCCGCTCAACG
TGCTCGCCGAACTGATCAACATCGGCACGCTCGCGGCGTTCTCGATGGTGTCGATCGCCGTGCTCGTGCTGCGCCGCACC
CATCCCGAGCTGCCGCGCGCGTTCCGCTGCCCGGGCGTGCCCGTGGTGCCGATCCTCGCGGTCGCGGCGTGCCTGTTCCT
GATGCTGAACCTGCAGCCCGTCACGTGGGCCGCGTTCGGCATCTGGCTCGTGATCGGCCTCGTGATCTACTTCCTGTACT
CGCGGCACCACTCGAAGCTCGCGCACGGCCACTCCGACACGCATTGA

Upstream 100 bases:

>100_bases
TCGCTGCGCCACCGCGGGACTTGCACGCCAAATCAGCTAAAATTATCGGTTTTCACTCAGTCGGCGCGCCGTGCCTGCGC
GTGCCGGCGATCCATCCGCA

Downstream 100 bases:

>100_bases
GCGCCGCCATGGCGCGCCTTCGCCGCGTGCCATGACGAACCCCACGCGGAGCCGGCCCCGGCTCCGCACGCCCCCTCTCC
CGCCCCCCCGCCGCCGCGCG

Product: amino acid permease-associated region

Products: L-tryptophan [Cytoplasm]; Proton [Cytoplasm]; Proton [Cytoplasm]; L-tyrosine [Cytoplasm]; Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSLFRKKNVDRMIAGAQAAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFA
SSIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLASSAVSVGWSGYLQSLLQGFGLTLPTVLTAAPGAVPGVTTWFNLP
AFLVMIVITTLLSIGIRESTRINNIMVFIKVSVVLLVIAVGLFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSS
AAEEVKNPKRDLPIGIIASLAVCAVLYVTVAAVATGIVPSAQYANISHPISYALQVAGEKWVAGFIDLGAVLGMLTVILV
MSYGQTRVIFAMSRDGLLPAALSRVHPRYATPFLTTWLVGLFFGLIAALVPLNVLAELINIGTLAAFSMVSIAVLVLRRT
HPELPRAFRCPGVPVVPILAVAACLFLMLNLQPVTWAAFGIWLVIGLVIYFLYSRHHSKLAHGHSDTH

Sequences:

>Translated_468_residues
MSLFRKKNVDRMIAGAQAAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFA
SSIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLASSAVSVGWSGYLQSLLQGFGLTLPTVLTAAPGAVPGVTTWFNLP
AFLVMIVITTLLSIGIRESTRINNIMVFIKVSVVLLVIAVGLFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSS
AAEEVKNPKRDLPIGIIASLAVCAVLYVTVAAVATGIVPSAQYANISHPISYALQVAGEKWVAGFIDLGAVLGMLTVILV
MSYGQTRVIFAMSRDGLLPAALSRVHPRYATPFLTTWLVGLFFGLIAALVPLNVLAELINIGTLAAFSMVSIAVLVLRRT
HPELPRAFRCPGVPVVPILAVAACLFLMLNLQPVTWAAFGIWLVIGLVIYFLYSRHHSKLAHGHSDTH
>Mature_467_residues
SLFRKKNVDRMIAGAQAAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFAS
SIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLASSAVSVGWSGYLQSLLQGFGLTLPTVLTAAPGAVPGVTTWFNLPA
FLVMIVITTLLSIGIRESTRINNIMVFIKVSVVLLVIAVGLFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSSA
AEEVKNPKRDLPIGIIASLAVCAVLYVTVAAVATGIVPSAQYANISHPISYALQVAGEKWVAGFIDLGAVLGMLTVILVM
SYGQTRVIFAMSRDGLLPAALSRVHPRYATPFLTTWLVGLFFGLIAALVPLNVLAELINIGTLAAFSMVSIAVLVLRRTH
PELPRAFRCPGVPVVPILAVAACLFLMLNLQPVTWAAFGIWLVIGLVIYFLYSRHHSKLAHGHSDTH

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of The Aromatic Amino Acids (Phenylalanine, Tyrosine, And Tryptophan). [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI181337167, Length=415, Percent_Identity=35.6626506024096, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI4507047, Length=436, Percent_Identity=35.5504587155963, Blast_Score=220, Evalue=3e-57,
Organism=Homo sapiens, GI258614005, Length=426, Percent_Identity=33.5680751173709, Blast_Score=218, Evalue=9e-57,
Organism=Homo sapiens, GI258614003, Length=426, Percent_Identity=33.5680751173709, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI258645169, Length=426, Percent_Identity=34.037558685446, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI110347453, Length=385, Percent_Identity=35.3246753246753, Blast_Score=202, Evalue=5e-52,
Organism=Homo sapiens, GI114326544, Length=433, Percent_Identity=32.5635103926097, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI114326550, Length=433, Percent_Identity=32.5635103926097, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI187423910, Length=493, Percent_Identity=26.369168356998, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI7657591, Length=493, Percent_Identity=26.369168356998, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI186910308, Length=413, Percent_Identity=25.90799031477, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI186910306, Length=413, Percent_Identity=25.90799031477, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI186910304, Length=413, Percent_Identity=25.90799031477, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI115648063, Length=413, Percent_Identity=24.455205811138, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI115648022, Length=413, Percent_Identity=24.455205811138, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI33286428, Length=482, Percent_Identity=25.103734439834, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI7657683, Length=404, Percent_Identity=25, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI71979932, Length=449, Percent_Identity=25.1670378619154, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI9790235, Length=299, Percent_Identity=24.0802675585284, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786302, Length=478, Percent_Identity=24.0585774058577, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082023, Length=450, Percent_Identity=24, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786789, Length=352, Percent_Identity=23.2954545454545, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786602, Length=476, Percent_Identity=23.5294117647059, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081915, Length=432, Percent_Identity=24.0740740740741, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081708, Length=486, Percent_Identity=23.0452674897119, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788480, Length=457, Percent_Identity=26.0393873085339, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI87081869, Length=464, Percent_Identity=22.8448275862069, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1786694, Length=253, Percent_Identity=26.8774703557312, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI87082250, Length=421, Percent_Identity=24.2280285035629, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367353, Length=351, Percent_Identity=25.3561253561254, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790653, Length=420, Percent_Identity=20.952380952381, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1789017, Length=366, Percent_Identity=22.4043715846995, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI48994972, Length=351, Percent_Identity=22.5071225071225, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1786908, Length=328, Percent_Identity=22.5609756097561, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=412, Percent_Identity=36.1650485436893, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17533459, Length=410, Percent_Identity=34.8780487804878, Blast_Score=214, Evalue=9e-56,
Organism=Caenorhabditis elegans, GI17531343, Length=405, Percent_Identity=34.0740740740741, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17540018, Length=433, Percent_Identity=25.1732101616628, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17568033, Length=427, Percent_Identity=24.1217798594848, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193208714, Length=433, Percent_Identity=27.4826789838337, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32566695, Length=433, Percent_Identity=27.4826789838337, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17537453, Length=330, Percent_Identity=26.969696969697, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71982608, Length=440, Percent_Identity=21.8181818181818, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71982612, Length=440, Percent_Identity=21.8181818181818, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI32566699, Length=374, Percent_Identity=25.668449197861, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6319991, Length=354, Percent_Identity=27.4011299435028, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24666159, Length=410, Percent_Identity=38.780487804878, Blast_Score=276, Evalue=3e-74,
Organism=Drosophila melanogaster, GI221512776, Length=410, Percent_Identity=38.780487804878, Blast_Score=275, Evalue=4e-74,
Organism=Drosophila melanogaster, GI24667468, Length=403, Percent_Identity=35.7320099255583, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI24668806, Length=429, Percent_Identity=34.032634032634, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI21356285, Length=429, Percent_Identity=34.032634032634, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24668802, Length=429, Percent_Identity=34.032634032634, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI161077963, Length=424, Percent_Identity=35.6132075471698, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI281366235, Length=413, Percent_Identity=34.8668280871671, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI116007820, Length=413, Percent_Identity=34.8668280871671, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI116007818, Length=414, Percent_Identity=34.7826086956522, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI85725152, Length=414, Percent_Identity=34.7826086956522, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21357367, Length=426, Percent_Identity=27.6995305164319, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI221331183, Length=474, Percent_Identity=24.4725738396624, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17647653, Length=474, Percent_Identity=24.4725738396624, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24664379, Length=474, Percent_Identity=24.4725738396624, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24651635, Length=425, Percent_Identity=24.2352941176471, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24651633, Length=425, Percent_Identity=24.2352941176471, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI45550968, Length=472, Percent_Identity=22.8813559322034, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19921172, Length=472, Percent_Identity=22.8813559322034, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641993, Length=418, Percent_Identity=26.555023923445, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641995, Length=418, Percent_Identity=26.555023923445, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49529; Mature: 49397

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLFRKKNVDRMIAGAQAAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALML
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHCCHHHHH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HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-tryptophan [Periplasm]; Proton [Periplasm]; Proton [Periplasm]; L-tyrosine [Periplasm]; Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: L-tryptophan [Periplasm] + Proton [Periplasm] = L-tryptophan [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] +

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]