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The map label for this gene is dppA [H]

Identifier: 116691063

GI number: 116691063

Start: 3358610

End: 3360238

Strand: Reverse

Name: dppA [H]

Synonym: Bcen2424_3045

Alternate gene names: 116691063

Gene position: 3360238-3358610 (Counterclockwise)

Preceding gene: 116691064

Following gene: 116691062

Centisome position: 96.45

GC content: 63.04

Gene sequence:

>1629_bases
ATGGAATACAACCGTCTGTTGCACACCCTGCGTGTTACCGCCATGGCAGGCGTGGCAGCGGCATCGCTCGGCGTCGCGGG
CTCTGCATTCGCACAGATCCCGAACAAAACGCTCGTCTACTGCTCAGAAGGCAGCCCGGCGGGTTTCGATTCCGCGCAAT
TTACGACCGGCGTCGATTTCACTGCCGCTACGTTCACCGTCTACAACCGCCTCGTCGAATTCGAGCGCGGCGGCACGAAG
GTCGAGCCCGGCCTCGCCGAGAAGTGGGACGTGTCGTCCGACGGCAAGGTGTACACGTTCCACCTGCGCCACGGCGTGAA
GTTCCACACGACCGACTTCTTCAAGCCGACGCGTGAATTCAACGCGGACGACGTCGTGTTCTCGTTCGAGCGCATGCTCG
ACCCGAACAATGCGTTCCGCAAGGCGTACCCGGTGTCGTTCCCGTACTTCACCGACATGGGCCTCGACAAGCTGATCACG
AAGATCGAGAAGGTCGATCCGTACACCGTGAAGTTCACGCTGGCCGAGCCGAACGCGCCGTTCATCCAGAACATGGCGAT
GGAATTCGCGTCGATCCTGTCGGCCGAATACGGCGACCAGCTGATGAAGGCCGGCAAGGCCGCCGACATCAACCAGAAGC
CGGTCGGCACGGGCCCGTTCATCTTCCGCAGCTACACGAAGGACGCGACGATCCGCTTCGATGGCAATCCTGATTACTGG
AAGAAGGGTGCGGTGAAGCTGTCGAAGCTGATCTTCTCGATCACGCCGGACCCGGGCGTGCGCGTGCAGAAGATCAAGCG
CAACGAATGCCAGGTGATGAGCTATCCGCGCCCGGCCGACATCGCGACGCTGAAGGCCGATTCGAACGTCGACATGCCGT
CGCAGGCCGGCTTCAACCTCGGCTACCTCGCGTACAACGTCGAGCACAAGCCGGTCGACAAGCTCGAAGTGCGTCAGGCG
CTCGACATGGCGATCAACAAGAAGGCGATCCTCGAGTCGGTCTACCAGGGCGCCGGCCAGGCCGCGACCGCACCGATGCC
GCCGACCCAATGGTCGTACGACAAGAACCTGAAGATGGCGGCCTACGACACCGCGAAGGCGAAGGCGCTGCTCGCGAAGG
CCGGCTTCCCGAACGGGTTCGAGATCACGCTGTGGGCGATGCCGGTGCAGCGCGCGTACAACCCGAACGCCCGCCTGATG
GCCGAGATGATCCAGGCCGACTGGGCGAAGATCGGCGTGAAGGCGAAGATCGTCACGTACGAGTGGGGCGAGTACATCAA
GCGCGCGCACTCGGGCGAGCAGGACACGATGCTGATCGGCTGGACGGGCGACAACGGCGATCCGGACAACTGGCTCGGCA
CGCTGCTCGGCTGCGAGGCGATCAAGGGCAACAACTTCTCGCACTGGTGCTACAAGCCGTTCGACGAGCTGGTGCAGAAG
GGCCGCACGACGACGGGCCAGGACGCGCGCACGAAGCTCTACACGCAGGCGCAGCAGATCTTCGCGCAACAGCTGCCGTT
CTCGCCGATCGCGAACTCGACGGTCTACCAGCCGGTGCGCAAGAACGTGGTCGACATGCGTATCGAGCCGCTCGGCTATG
CGCGTTTCGACGGTGTCAGCGTGAAGTAA

Upstream 100 bases:

>100_bases
AGTTTTTTCTCCAGCTTGTTGCAGGATCGCTAGCTCAAGTAATATCCGCGTACGCCGGACCCTGGCGGGGCCGGTTCCGA
TCTGGAGACCTGGAGGAAAC

Downstream 100 bases:

>100_bases
CCCGGCTGGCGTAAGCTGTCGTCATTGAGAAAACCGGCTTGAAATCATCCGGCGACGAGGGGTCAAAAGCCCCTCGTCGC
CGGTCGCACATTTCCCACAA

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MEYNRLLHTLRVTAMAGVAAASLGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDFTAATFTVYNRLVEFERGGTK
VEPGLAEKWDVSSDGKVYTFHLRHGVKFHTTDFFKPTREFNADDVVFSFERMLDPNNAFRKAYPVSFPYFTDMGLDKLIT
KIEKVDPYTVKFTLAEPNAPFIQNMAMEFASILSAEYGDQLMKAGKAADINQKPVGTGPFIFRSYTKDATIRFDGNPDYW
KKGAVKLSKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADSNVDMPSQAGFNLGYLAYNVEHKPVDKLEVRQA
LDMAINKKAILESVYQGAGQAATAPMPPTQWSYDKNLKMAAYDTAKAKALLAKAGFPNGFEITLWAMPVQRAYNPNARLM
AEMIQADWAKIGVKAKIVTYEWGEYIKRAHSGEQDTMLIGWTGDNGDPDNWLGTLLGCEAIKGNNFSHWCYKPFDELVQK
GRTTTGQDARTKLYTQAQQIFAQQLPFSPIANSTVYQPVRKNVVDMRIEPLGYARFDGVSVK

Sequences:

>Translated_542_residues
MEYNRLLHTLRVTAMAGVAAASLGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDFTAATFTVYNRLVEFERGGTK
VEPGLAEKWDVSSDGKVYTFHLRHGVKFHTTDFFKPTREFNADDVVFSFERMLDPNNAFRKAYPVSFPYFTDMGLDKLIT
KIEKVDPYTVKFTLAEPNAPFIQNMAMEFASILSAEYGDQLMKAGKAADINQKPVGTGPFIFRSYTKDATIRFDGNPDYW
KKGAVKLSKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADSNVDMPSQAGFNLGYLAYNVEHKPVDKLEVRQA
LDMAINKKAILESVYQGAGQAATAPMPPTQWSYDKNLKMAAYDTAKAKALLAKAGFPNGFEITLWAMPVQRAYNPNARLM
AEMIQADWAKIGVKAKIVTYEWGEYIKRAHSGEQDTMLIGWTGDNGDPDNWLGTLLGCEAIKGNNFSHWCYKPFDELVQK
GRTTTGQDARTKLYTQAQQIFAQQLPFSPIANSTVYQPVRKNVVDMRIEPLGYARFDGVSVK
>Mature_542_residues
MEYNRLLHTLRVTAMAGVAAASLGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDFTAATFTVYNRLVEFERGGTK
VEPGLAEKWDVSSDGKVYTFHLRHGVKFHTTDFFKPTREFNADDVVFSFERMLDPNNAFRKAYPVSFPYFTDMGLDKLIT
KIEKVDPYTVKFTLAEPNAPFIQNMAMEFASILSAEYGDQLMKAGKAADINQKPVGTGPFIFRSYTKDATIRFDGNPDYW
KKGAVKLSKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADSNVDMPSQAGFNLGYLAYNVEHKPVDKLEVRQA
LDMAINKKAILESVYQGAGQAATAPMPPTQWSYDKNLKMAAYDTAKAKALLAKAGFPNGFEITLWAMPVQRAYNPNARLM
AEMIQADWAKIGVKAKIVTYEWGEYIKRAHSGEQDTMLIGWTGDNGDPDNWLGTLLGCEAIKGNNFSHWCYKPFDELVQK
GRTTTGQDARTKLYTQAQQIFAQQLPFSPIANSTVYQPVRKNVVDMRIEPLGYARFDGVSVK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=519, Percent_Identity=54.7206165703276, Blast_Score=599, Evalue=1e-172,
Organism=Escherichia coli, GI1787551, Length=538, Percent_Identity=34.3866171003717, Blast_Score=334, Evalue=7e-93,
Organism=Escherichia coli, GI1787052, Length=459, Percent_Identity=29.1938997821351, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1787762, Length=502, Percent_Identity=26.0956175298805, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1789887, Length=469, Percent_Identity=27.0788912579957, Blast_Score=125, Evalue=9e-30,
Organism=Escherichia coli, GI1787495, Length=537, Percent_Identity=23.463687150838, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI87081878, Length=567, Percent_Identity=23.8095238095238, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1789397, Length=509, Percent_Identity=23.5756385068762, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60347; Mature: 60347

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYNRLLHTLRVTAMAGVAAASLGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDF
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCCCCCCEECCCCH
TAATFTVYNRLVEFERGGTKVEPGLAEKWDVSSDGKVYTFHLRHGVKFHTTDFFKPTREF
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCHHCC
NADDVVFSFERMLDPNNAFRKAYPVSFPYFTDMGLDKLITKIEKVDPYTVKFTLAEPNAP
CCCHHHHHHHHHCCCCCHHHHCCCCCCCCHHHCCHHHHHHHHHHCCCEEEEEEEECCCCH
FIQNMAMEFASILSAEYGDQLMKAGKAADINQKPVGTGPFIFRSYTKDATIRFDGNPDYW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCHH
KKGAVKLSKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADSNVDMPSQAGFNL
HHHHHEEEHHHEEECCCCCCEEEEECCCCCEEECCCCCCCEEEEECCCCCCCCCCCCCCE
GYLAYNVEHKPVDKLEVRQALDMAINKKAILESVYQGAGQAATAPMPPTQWSYDKNLKMA
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEE
AYDTAKAKALLAKAGFPNGFEITLWAMPVQRAYNPNARLMAEMIQADWAKIGVKAKIVTY
EECHHHHHHHHHHCCCCCCCEEEEEEEEHHHCCCCCHHHHHHHHHHHHHHCCEEEEEEEE
EWGEYIKRAHSGEQDTMLIGWTGDNGDPDNWLGTLLGCEAIKGNNFSHWCYKPFDELVQK
HHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHC
GRTTTGQDARTKLYTQAQQIFAQQLPFSPIANSTVYQPVRKNVVDMRIEPLGYARFDGVS
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHEEECCCCCEECCCCC
VK
CC
>Mature Secondary Structure
MEYNRLLHTLRVTAMAGVAAASLGVAGSAFAQIPNKTLVYCSEGSPAGFDSAQFTTGVDF
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCCCCCCEECCCCH
TAATFTVYNRLVEFERGGTKVEPGLAEKWDVSSDGKVYTFHLRHGVKFHTTDFFKPTREF
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCHHCC
NADDVVFSFERMLDPNNAFRKAYPVSFPYFTDMGLDKLITKIEKVDPYTVKFTLAEPNAP
CCCHHHHHHHHHCCCCCHHHHCCCCCCCCHHHCCHHHHHHHHHHCCCEEEEEEEECCCCH
FIQNMAMEFASILSAEYGDQLMKAGKAADINQKPVGTGPFIFRSYTKDATIRFDGNPDYW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCHH
KKGAVKLSKLIFSITPDPGVRVQKIKRNECQVMSYPRPADIATLKADSNVDMPSQAGFNL
HHHHHEEEHHHEEECCCCCCEEEEECCCCCEEECCCCCCCEEEEECCCCCCCCCCCCCCE
GYLAYNVEHKPVDKLEVRQALDMAINKKAILESVYQGAGQAATAPMPPTQWSYDKNLKMA
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEE
AYDTAKAKALLAKAGFPNGFEITLWAMPVQRAYNPNARLMAEMIQADWAKIGVKAKIVTY
EECHHHHHHHHHHCCCCCCCEEEEEEEEHHHCCCCCHHHHHHHHHHHHHHCCEEEEEEEE
EWGEYIKRAHSGEQDTMLIGWTGDNGDPDNWLGTLLGCEAIKGNNFSHWCYKPFDELVQK
HHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHC
GRTTTGQDARTKLYTQAQQIFAQQLPFSPIANSTVYQPVRKNVVDMRIEPLGYARFDGVS
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHEEECCCCCEECCCCC
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]