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The map label for this gene is dppB [H]

Identifier: 116691062

GI number: 116691062

Start: 3357481

End: 3358491

Strand: Reverse

Name: dppB [H]

Synonym: Bcen2424_3044

Alternate gene names: 116691062

Gene position: 3358491-3357481 (Counterclockwise)

Preceding gene: 116691063

Following gene: 116691061

Centisome position: 96.4

GC content: 66.57

Gene sequence:

>1011_bases
ATGCTCAGATTCGTGTTGCGCCGCGTGGGGATGGTGATCCCGACTTTCATCGGCATCACCATCCTGGCGTTTGCGCTGAT
TCACCTGATACCGGGCGACCCCATCGAAGTGATGATGGGCGAGCGCGGCGTCGATCCCGCGATGCACGCGGAGGCGATGA
AACGCCTCGGGCTCGACGAGCCGCTGCCGCTGCAGTATCTGCACTACATCGGCCGGGCGCTGCATGGTGACCTCGGCATG
TCGATCATCACCAACACGAGCGTCGCGGGCGAGTTCTTCGCGCGCTTTCCGGCGACCGTGGAACTGTCGCTGTGCGCGCT
CGTGTTCGCGCTCGCGGTCGGCCTGCCGGCCGGGGTGATCGCCGCGCTGCGGCGCGGCTCGGTCATCGACCACGGCGTGA
TGGGCACCGCGCTCACCGGCTACTCGATGCCGATCTTCTGGTGGGGGCTGATCCTCATCATGGTGTTTTCGTCGACCCTC
GGCTGGACGCCCGTGTCGGGGCGCATCGCGGTCGAATACGATTTCCCGCACCCGACCGGCTTCATGCTGATCGACGCGCT
GCTCGCGCCGGACGAAGGTTCGTTCAAGTCGGCGGTGAGCCACCTGATCCTGCCCGCGATCGTGCTCGGCACGATCCCGC
TCGCGGTGATCGCGCGGATGACGCGCTCGTCGATGCTCGAAGTGCTGCGCGAGGACTACATCCGCACCGCCCGCGCGAAA
GGGCTGTCGCCCGTGCGCGTGGTCGTCGTGCATGCGCTGCGCAATGCGCTGATCCCGGTCGTCACCGTGATTGGCCTGCA
GATCGGCACGCTGCTTGCTGGCGCGGTGCTGACCGAGACGCTCTTTTCGTGGCCCGGCGTCGGCAAGTGGCTGATCGATG
CGATCGGCCGCCGCGACTATCCGGTCGTCCAGGGCGGCATCCTGCTGATCGCGACGCTCGTGATCGTCGTGAACCTGGTC
GTCGACCTGCTGTACGGCGTGCTGAATCCGCGCATCCGCCACACGAGGTAA

Upstream 100 bases:

>100_bases
TCGTCATTGAGAAAACCGGCTTGAAATCATCCGGCGACGAGGGGTCAAAAGCCCCTCGTCGCCGGTCGCACATTTCCCAC
AAGAAAATACGAGACGCATC

Downstream 100 bases:

>100_bases
TCCCATGAGCAATCTGCAAAATACCCTGCCGACCGAATCCGCGCCGGCCGGCGGCCGTGCGCTCGCGCTGCGCGAGTTCT
GGGCCAACTTCTCGCGCAAC

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MLRFVLRRVGMVIPTFIGITILAFALIHLIPGDPIEVMMGERGVDPAMHAEAMKRLGLDEPLPLQYLHYIGRALHGDLGM
SIITNTSVAGEFFARFPATVELSLCALVFALAVGLPAGVIAALRRGSVIDHGVMGTALTGYSMPIFWWGLILIMVFSSTL
GWTPVSGRIAVEYDFPHPTGFMLIDALLAPDEGSFKSAVSHLILPAIVLGTIPLAVIARMTRSSMLEVLREDYIRTARAK
GLSPVRVVVVHALRNALIPVVTVIGLQIGTLLAGAVLTETLFSWPGVGKWLIDAIGRRDYPVVQGGILLIATLVIVVNLV
VDLLYGVLNPRIRHTR

Sequences:

>Translated_336_residues
MLRFVLRRVGMVIPTFIGITILAFALIHLIPGDPIEVMMGERGVDPAMHAEAMKRLGLDEPLPLQYLHYIGRALHGDLGM
SIITNTSVAGEFFARFPATVELSLCALVFALAVGLPAGVIAALRRGSVIDHGVMGTALTGYSMPIFWWGLILIMVFSSTL
GWTPVSGRIAVEYDFPHPTGFMLIDALLAPDEGSFKSAVSHLILPAIVLGTIPLAVIARMTRSSMLEVLREDYIRTARAK
GLSPVRVVVVHALRNALIPVVTVIGLQIGTLLAGAVLTETLFSWPGVGKWLIDAIGRRDYPVVQGGILLIATLVIVVNLV
VDLLYGVLNPRIRHTR
>Mature_336_residues
MLRFVLRRVGMVIPTFIGITILAFALIHLIPGDPIEVMMGERGVDPAMHAEAMKRLGLDEPLPLQYLHYIGRALHGDLGM
SIITNTSVAGEFFARFPATVELSLCALVFALAVGLPAGVIAALRRGSVIDHGVMGTALTGYSMPIFWWGLILIMVFSSTL
GWTPVSGRIAVEYDFPHPTGFMLIDALLAPDEGSFKSAVSHLILPAIVLGTIPLAVIARMTRSSMLEVLREDYIRTARAK
GLSPVRVVVVHALRNALIPVVTVIGLQIGTLLAGAVLTETLFSWPGVGKWLIDAIGRRDYPVVQGGILLIATLVIVVNLV
VDLLYGVLNPRIRHTR

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=66.0766961651917, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI1787053, Length=335, Percent_Identity=41.4925373134328, Blast_Score=260, Evalue=9e-71,
Organism=Escherichia coli, GI1787761, Length=316, Percent_Identity=47.1518987341772, Blast_Score=234, Evalue=8e-63,
Organism=Escherichia coli, GI1787550, Length=274, Percent_Identity=40.1459854014599, Blast_Score=209, Evalue=1e-55,
Organism=Escherichia coli, GI1789888, Length=336, Percent_Identity=36.3095238095238, Blast_Score=207, Evalue=6e-55,
Organism=Escherichia coli, GI1787497, Length=335, Percent_Identity=34.9253731343284, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1788504, Length=369, Percent_Identity=25.2032520325203, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36332; Mature: 36332

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFVLRRVGMVIPTFIGITILAFALIHLIPGDPIEVMMGERGVDPAMHAEAMKRLGLDE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCC
PLPLQYLHYIGRALHGDLGMSIITNTSVAGEFFARFPATVELSLCALVFALAVGLPAGVI
CCCHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHH
AALRRGSVIDHGVMGTALTGYSMPIFWWGLILIMVFSSTLGWTPVSGRIAVEYDFPHPTG
HHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCH
FMLIDALLAPDEGSFKSAVSHLILPAIVLGTIPLAVIARMTRSSMLEVLREDYIRTARAK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLSPVRVVVVHALRNALIPVVTVIGLQIGTLLAGAVLTETLFSWPGVGKWLIDAIGRRDY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
PVVQGGILLIATLVIVVNLVVDLLYGVLNPRIRHTR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLRFVLRRVGMVIPTFIGITILAFALIHLIPGDPIEVMMGERGVDPAMHAEAMKRLGLDE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCC
PLPLQYLHYIGRALHGDLGMSIITNTSVAGEFFARFPATVELSLCALVFALAVGLPAGVI
CCCHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHH
AALRRGSVIDHGVMGTALTGYSMPIFWWGLILIMVFSSTLGWTPVSGRIAVEYDFPHPTG
HHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCH
FMLIDALLAPDEGSFKSAVSHLILPAIVLGTIPLAVIARMTRSSMLEVLREDYIRTARAK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLSPVRVVVVHALRNALIPVVTVIGLQIGTLLAGAVLTETLFSWPGVGKWLIDAIGRRDY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
PVVQGGILLIATLVIVVNLVVDLLYGVLNPRIRHTR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]