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The map label for this gene is argM [C]

Identifier: 116691013

GI number: 116691013

Start: 3305571

End: 3307013

Strand: Direct

Name: argM [C]

Synonym: Bcen2424_2995

Alternate gene names: 116691013

Gene position: 3305571-3307013 (Clockwise)

Preceding gene: 116691012

Following gene: 116691014

Centisome position: 94.88

GC content: 66.67

Gene sequence:

>1443_bases
ATGACTTACCGCAACGAATCTGCCTGGGTCCAGCCGGCCGCGCCGAGCGCCGCGGCCGCCGCGCCGCGCGCGACGCAGGC
GCGCACGACCGCCGAATACCGCGCGCTCGACGCCGCGCACCACATTCACCCGTTCTCCGACATGGGCGCGCTCAATCGCG
CCGGCAGCCGCGTGATCGTGAAGGCCGACGGCGTCTACCTGTGGGACTCGGACGGCAACAAGGTGATCGACGGGATGGCC
GGCCTGTGGTGCGTGAACGTCGGCTACGGCCGCAAGGAACTCGCCGACGCCGCGTATCGCCAGATCCAGGAACTGCCGTT
CTACAACACGTTCTTCAAGACCACGCACCCGCCGGTGATCGAGCTTTCCGCGATGCTCGCGGAAGTGACGCCTGCCGGCT
TCAACCACTTCTTCTATTGCAACAGCGGCTCGGAAGGCAACGACACCGTGCTGCGTCTCGTGCATCAGTACTGGCGCGTG
CAAGGCAAACCGCAGAAGAAATACGTGATCTCGCGCAAGAACGGTTACCACGGCTCGACGATCGCGGGCGGCACGCTCGG
CGGGATGGGCTACATGCACGAGCAGATGCCGTCGAAGGTCGAGCACATCGTGCACATCGACCAGCCGTATTTCTTCGGCG
AAGCGCAAGCAGGCGAGACGCCCGAAGCATTCGGCCTCGCGCGTGCGCAGCAGCTCGAAGCGAAGATCCTCGAACTCGGC
GCGGAGAACGTCGCGGCGTTCATCGGCGAACCGTTCCAGGGCGCGGGCGGCGTGATCTTCCCGCCGTCGACGTACTGGCC
GGAGATCCAGCGGATCTGCCGCAAGTACGACATCCTGCTGGTCGCCGACGAAGTGATCGGCGGCTTCGGGCGCACCGGCG
AATGGTTCGCGCACCAGCACTTCGGCTTCGAGCCGGACCTGATCACGATGGCGAAGGGCCTCACGTCGGGCTACGTGCCG
ATGGGCGCCGTGGGCATTCACGAGCGCGTCGCGCGCCCGATCATCGACAACGGCGAATTCAATCACGGCCTCACGTACTC
GGGCCACCCGGTGGCGGCGGCCGTCGCGGTCGCGAACCTGAAGCTGCTGCGCGACGAGGGGATCGTCGAGCGGGTGAAGA
CCGACACCGGCCCGTACTTCCAGGCGCTGATGCGCGAAACCTTCGCGCGTCATCCGATCGTCGGCGAAGTGCACGGCCAC
GGGATGGTCGCGAGCCTGCAACTGGCCGAAGCGCCGGCCGAACGCCGCCGCTTCGCGAACGGCGGCGACGTCGGCACGAT
CTGCCGCGACTTCTGCTTCAACGGCAACCTGATCATGCGCGCGACCGGCGACCGGATGCTGCTGTCGCCGCCGCTCGTGG
TCTCGCGCCAGGAAATCGATGAACTCGTGTCGAAGGCGAAGAAGGCCGTCGATGCCACCGCCCGGCAACTGGGCGTTTCG
TAA

Upstream 100 bases:

>100_bases
GAATACGAAGCGTTCTTCCGCGTGATCAGCTCGTGGGAACGCCGCCATCTGCTGCTGCACGTTTAAGCGTGCCAACCGCA
TACGGAATCACGGAGGAAAC

Downstream 100 bases:

>100_bases
CGGTTTTGCCTACAGGCGTGCGGCGGGCGCCGCACGCCGCCATCACTCAAGGGAATTCCACCATGCGTGCCTGCATTCTT
CGCCAAGCCTGTTCCGTCGC

Product: putative aminotransferase

Products: L-glutamate; N2-succinylglutamic-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MTYRNESAWVQPAAPSAAAAAPRATQARTTAEYRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKVIDGMA
GLWCVNVGYGRKELADAAYRQIQELPFYNTFFKTTHPPVIELSAMLAEVTPAGFNHFFYCNSGSEGNDTVLRLVHQYWRV
QGKPQKKYVISRKNGYHGSTIAGGTLGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQAGETPEAFGLARAQQLEAKILELG
AENVAAFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSGYVP
MGAVGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKTDTGPYFQALMRETFARHPIVGEVHGH
GMVASLQLAEAPAERRRFANGGDVGTICRDFCFNGNLIMRATGDRMLLSPPLVVSRQEIDELVSKAKKAVDATARQLGVS

Sequences:

>Translated_480_residues
MTYRNESAWVQPAAPSAAAAAPRATQARTTAEYRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKVIDGMA
GLWCVNVGYGRKELADAAYRQIQELPFYNTFFKTTHPPVIELSAMLAEVTPAGFNHFFYCNSGSEGNDTVLRLVHQYWRV
QGKPQKKYVISRKNGYHGSTIAGGTLGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQAGETPEAFGLARAQQLEAKILELG
AENVAAFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSGYVP
MGAVGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKTDTGPYFQALMRETFARHPIVGEVHGH
GMVASLQLAEAPAERRRFANGGDVGTICRDFCFNGNLIMRATGDRMLLSPPLVVSRQEIDELVSKAKKAVDATARQLGVS
>Mature_479_residues
TYRNESAWVQPAAPSAAAAAPRATQARTTAEYRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKVIDGMAG
LWCVNVGYGRKELADAAYRQIQELPFYNTFFKTTHPPVIELSAMLAEVTPAGFNHFFYCNSGSEGNDTVLRLVHQYWRVQ
GKPQKKYVISRKNGYHGSTIAGGTLGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQAGETPEAFGLARAQQLEAKILELGA
ENVAAFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSGYVPM
GAVGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKTDTGPYFQALMRETFARHPIVGEVHGHG
MVASLQLAEAPAERRRFANGGDVGTICRDFCFNGNLIMRATGDRMLLSPPLVVSRQEIDELVSKAKKAVDATARQLGVS

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=439, Percent_Identity=26.1958997722096, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI24119277, Length=362, Percent_Identity=29.5580110497238, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI37574042, Length=379, Percent_Identity=27.9683377308707, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI226442705, Length=376, Percent_Identity=28.1914893617021, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI13994255, Length=427, Percent_Identity=25.7611241217799, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI226442709, Length=332, Percent_Identity=27.4096385542169, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI284507298, Length=230, Percent_Identity=30, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI188536080, Length=427, Percent_Identity=23.1850117096019, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI38679950, Length=427, Percent_Identity=23.1850117096019, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI38679946, Length=427, Percent_Identity=23.1850117096019, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1788044, Length=403, Percent_Identity=28.7841191066998, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI145693181, Length=410, Percent_Identity=26.0975609756098, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI1786991, Length=453, Percent_Identity=29.1390728476821, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1789759, Length=415, Percent_Identity=26.7469879518072, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789016, Length=359, Percent_Identity=25.3481894150418, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787560, Length=362, Percent_Identity=28.1767955801105, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786349, Length=331, Percent_Identity=24.4712990936556, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25144271, Length=425, Percent_Identity=26.8235294117647, Blast_Score=147, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI32564660, Length=441, Percent_Identity=28.5714285714286, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI71992977, Length=371, Percent_Identity=26.1455525606469, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI25144274, Length=333, Percent_Identity=28.2282282282282, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=447, Percent_Identity=23.2662192393736, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323470, Length=454, Percent_Identity=27.0925110132159, Blast_Score=162, Evalue=9e-41,
Organism=Saccharomyces cerevisiae, GI6324432, Length=430, Percent_Identity=24.4186046511628, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324386, Length=367, Percent_Identity=29.1553133514986, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21357415, Length=444, Percent_Identity=26.8018018018018, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI28574759, Length=435, Percent_Identity=28.5057471264368, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI161085790, Length=421, Percent_Identity=28.2660332541568, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI21356575, Length=435, Percent_Identity=25.2873563218391, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281366494, Length=352, Percent_Identity=24.1477272727273, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24667139, Length=352, Percent_Identity=24.1477272727273, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24667143, Length=352, Percent_Identity=24.1477272727273, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 52459; Mature: 52328

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYRNESAWVQPAAPSAAAAAPRATQARTTAEYRALDAAHHIHPFSDMGALNRAGSRVIV
CCCCCCCCEECCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEE
KADGVYLWDSDGNKVIDGMAGLWCVNVGYGRKELADAAYRQIQELPFYNTFFKTTHPPVI
EECCEEEECCCCCCHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHH
ELSAMLAEVTPAGFNHFFYCNSGSEGNDTVLRLVHQYWRVQGKPQKKYVISRKNGYHGST
HHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
IAGGTLGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQAGETPEAFGLARAQQLEAKILELG
CCCCCCCCHHHHHHHHHHHHHHHEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHC
AENVAAFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQH
HHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHCEEEEEHHHHCCCCCCCHHHHHHC
FGFEPDLITMAKGLTSGYVPMGAVGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANL
CCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
KLLRDEGIVERVKTDTGPYFQALMRETFARHPIVGEVHGHGMVASLQLAEAPAERRRFAN
HHHHHCCHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEEHHHCCHHHHHCCC
GGDVGTICRDFCFNGNLIMRATGDRMLLSPPLVVSRQEIDELVSKAKKAVDATARQLGVS
CCCHHHHHHHHHCCCCEEEEECCCEEEECCCCEECHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TYRNESAWVQPAAPSAAAAAPRATQARTTAEYRALDAAHHIHPFSDMGALNRAGSRVIV
CCCCCCCEECCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEE
KADGVYLWDSDGNKVIDGMAGLWCVNVGYGRKELADAAYRQIQELPFYNTFFKTTHPPVI
EECCEEEECCCCCCHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHH
ELSAMLAEVTPAGFNHFFYCNSGSEGNDTVLRLVHQYWRVQGKPQKKYVISRKNGYHGST
HHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
IAGGTLGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQAGETPEAFGLARAQQLEAKILELG
CCCCCCCCHHHHHHHHHHHHHHHEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHC
AENVAAFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQH
HHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHCEEEEEHHHHCCCCCCCHHHHHHC
FGFEPDLITMAKGLTSGYVPMGAVGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANL
CCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
KLLRDEGIVERVKTDTGPYFQALMRETFARHPIVGEVHGHGMVASLQLAEAPAERRRFAN
HHHHHCCHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEEHHHCCHHHHHCCC
GGDVGTICRDFCFNGNLIMRATGDRMLLSPPLVVSRQEIDELVSKAKKAVDATARQLGVS
CCCHHHHHHHHHCCCCEEEEECCCEEEECCCCEECHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-alpha-acetylornithine; 2-oxoglutarate [C]

Specific reaction: N-alpha-acetylornithine + 2-oxoglutarate = N-acetylglutamate semialdehyde + L-glutamate N2-succinylornithine + 2-oxoglutarate = N2-succinylglutamic-semialdehyde + L-glutamate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]