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The map label for this gene is dapA2 [H]

Identifier: 116690964

GI number: 116690964

Start: 3259424

End: 3260317

Strand: Direct

Name: dapA2 [H]

Synonym: Bcen2424_2946

Alternate gene names: 116690964

Gene position: 3259424-3260317 (Clockwise)

Preceding gene: 116690961

Following gene: 116690968

Centisome position: 93.56

GC content: 71.81

Gene sequence:

>894_bases
ATGAACACACGTTTCGAAGGTATCTGGCTGCCGATCATCACGCCGTTTCATCATGGCGAGGTCGACCATGCAGCGCTCGC
GCGGCTCGCGCGCCACTATGCGACCGCGGGCATCGCAGGCTTCGTCGCGGGGGCGACGACCGGTGAAGGCGTGCTGCTCG
ACGCGCGCGAACAGGACGCGGTGTTCGCGACGCTGCGCGATGCGGCGCCCGCGCTGCCGATCGTCGTCGGGCTGACCGCG
AGCGCCACGCACTTCGCGGCCGCCCGCGCACGCGAACTCGCGGCGCTGCGCCCCGACGGGCTGCTCGTCACACCGCCCGT
CTACGTGCGGCCGACGCAGGACGGCATCCGTCGCCACGTCGAAGCGATCGTCGACGCGGCCGACCTGCCGGTGCTCGTCT
ACAACATCCCGTACCGCACCGGCGTGAACGTCGAACTGGACACGCTGCAGGCGCTCGCGTGCGACTCGCGCGTCGCCGGC
ATCAAGGAATGCGGCGGTACGCTCGACCGGATGAGCCGGCTGGTGCACGACACGCCGCTCGCGGTCCTGTCCGGCGACGA
CAACCAGAACTTCGCGGCGATGTGCGCGGGGGCGCACGGCGCGATCGCGAGCAGCGCCCACGTGCTGCCTGAATGGCATG
TGCGCATCCATGCGCTGCTGCGCGACGGGCGGCTCGCCGATGCGCGGCGCCTGTCGGTCGCGCTGCAGCCGCTCGTCGCG
GCGCTGTTCGCGGAACCCAACCCGGCGCCGGTGAAGGCCGTGCTCGCCGCGCAAGGGTGGTGCGAGGACGGGTTGCGGCT
GCCGTTCGTGCCGGCGAGCGAGGGGTTGCGGGAGCGGTTGGCGGCGATTTGCGCGACGCTCGAGGCGTCCGCGCAAATTA
CCGCGGCGGCGTAG

Upstream 100 bases:

>100_bases
TGCCCGCAGGTCGTTTCATTCTCCTTGCACGCACGCCTCGCTCCGGCACACCGCCGGCGGAACGGTTCCTTCCCACTCCG
TTTCCACCATGAGGCTTTGC

Downstream 100 bases:

>100_bases
GATTTCGCGCCGAAAACTGTTTCAAACCGTCAAAATCCGTGACGCGCCATACTGCGAAAGATGGCCGTCCGCGGTCACGA
GCAACAGCGGTTCGTACCAC

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS 2 [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNTRFEGIWLPIITPFHHGEVDHAALARLARHYATAGIAGFVAGATTGEGVLLDAREQDAVFATLRDAAPALPIVVGLTA
SATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHVEAIVDAADLPVLVYNIPYRTGVNVELDTLQALACDSRVAG
IKECGGTLDRMSRLVHDTPLAVLSGDDNQNFAAMCAGAHGAIASSAHVLPEWHVRIHALLRDGRLADARRLSVALQPLVA
ALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASEGLRERLAAICATLEASAQITAAA

Sequences:

>Translated_297_residues
MNTRFEGIWLPIITPFHHGEVDHAALARLARHYATAGIAGFVAGATTGEGVLLDAREQDAVFATLRDAAPALPIVVGLTA
SATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHVEAIVDAADLPVLVYNIPYRTGVNVELDTLQALACDSRVAG
IKECGGTLDRMSRLVHDTPLAVLSGDDNQNFAAMCAGAHGAIASSAHVLPEWHVRIHALLRDGRLADARRLSVALQPLVA
ALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASEGLRERLAAICATLEASAQITAAA
>Mature_297_residues
MNTRFEGIWLPIITPFHHGEVDHAALARLARHYATAGIAGFVAGATTGEGVLLDAREQDAVFATLRDAAPALPIVVGLTA
SATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHVEAIVDAADLPVLVYNIPYRTGVNVELDTLQALACDSRVAG
IKECGGTLDRMSRLVHDTPLAVLSGDDNQNFAAMCAGAHGAIASSAHVLPEWHVRIHALLRDGRLADARRLSVALQPLVA
ALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASEGLRERLAAICATLEASAQITAAA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=233, Percent_Identity=27.0386266094421, Blast_Score=88, Evalue=9e-18,
Organism=Escherichia coli, GI1788823, Length=284, Percent_Identity=35.5633802816901, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1789620, Length=295, Percent_Identity=27.7966101694915, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87082415, Length=289, Percent_Identity=25.9515570934256, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786463, Length=234, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31328; Mature: 31328

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRFEGIWLPIITPFHHGEVDHAALARLARHYATAGIAGFVAGATTGEGVLLDAREQDA
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCH
VFATLRDAAPALPIVVGLTASATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHV
HHEEHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEECCCEEEECCHHHHHHHH
EAIVDAADLPVLVYNIPYRTGVNVELDTLQALACDSRVAGIKECGGTLDRMSRLVHDTPL
HHHHHHCCCCEEEEECCCCCCCCEEHHHHHHHHHCHHHCCHHHHCCHHHHHHHHHHCCCE
AVLSGDDNQNFAAMCAGAHGAIASSAHVLPEWHVRIHALLRDGRLADARRLSVALQPLVA
EEEECCCCCCEEEEEECCCCCCCCCCCCCCHHHHEEEEHHHCCCCCHHHHHHHHHHHHHH
ALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASEGLRERLAAICATLEASAQITAAA
HHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure
MNTRFEGIWLPIITPFHHGEVDHAALARLARHYATAGIAGFVAGATTGEGVLLDAREQDA
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCH
VFATLRDAAPALPIVVGLTASATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHV
HHEEHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEECCCEEEECCHHHHHHHH
EAIVDAADLPVLVYNIPYRTGVNVELDTLQALACDSRVAGIKECGGTLDRMSRLVHDTPL
HHHHHHCCCCEEEEECCCCCCCCEEHHHHHHHHHCHHHCCHHHHCCHHHHHHHHHHCCCE
AVLSGDDNQNFAAMCAGAHGAIASSAHVLPEWHVRIHALLRDGRLADARRLSVALQPLVA
EEEECCCCCCEEEEEECCCCCCCCCCCCCCHHHHEEEEHHHCCCCCHHHHHHHHHHHHHH
ALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASEGLRERLAAICATLEASAQITAAA
HHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]