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The map label for this gene is bioD [H]

Identifier: 116690951

GI number: 116690951

Start: 3242688

End: 3243407

Strand: Direct

Name: bioD [H]

Synonym: Bcen2424_2933

Alternate gene names: 116690951

Gene position: 3242688-3243407 (Clockwise)

Preceding gene: 116690950

Following gene: 116690952

Centisome position: 93.08

GC content: 72.78

Gene sequence:

>720_bases
ATGACCGCTCCGCTCTCCGTCTTCGTCACCGGCACCGACACCGAGATCGGCAAGACCTTCGTGTCGGCCGCGATGCTGCA
CGGCTTCGCGCGGCACGGGCTGCGCGCGGCCGCGCTGAAGCCGGTCGCGGCCGGCGCGTACGAACGCGACGGCGTGTGGC
GCAACGAGGACGCCGACCAGCTCGACGCCGCCGCGAACGTCGCGCTGCCGCCCGAGCTGCGCACGCCGTTCCTGCTGAAA
GCGCCGGCCGCACCGCATATCGTCGCCGCGCAGGAGGGCGTGACGCTCGACCTCGACACGATCGTCGCGTGCCATCGCGA
AGCGCTGACGCGCGCGGACGTCGTCGTCGTCGAAGGCGTCGGCGGCTTTCGCGTGCCGCTGAACGATACGCAGGACACCG
CCGATCTCGCGGTCGCGCTCGGCCTGCCCGTCGTGCTGGTGGTCGGCGTCCGGCTCGGCTGCATCAGCCACGCGTTGCTG
ACGGCCGATGCGATTCGCCAGCGCGGCCTCACGCTCGCGGGCTGGGTCGCGAACCACGTCGACCCGGCCATGTCGTTCGC
CGACGAGAACGTCGCGACGATTCGCGACTGGCTCGCGCGCGAGCACCGCGCGCCACTCATCGGCCGCATCGCGCACATGA
CGCCGGCCGCCCCCGAATCCGCCGCGGCGATGCTCGACATCGCCGCGCTCGTCGAGTCGCTGCGCACCGCGCGGCGTTGA

Upstream 100 bases:

>100_bases
CGCATTCGTTCGACGATCTCGCCAGGCTCGAAGCCGCGTTGATCGAGGCCAGCGAGGCGGCCGCGGCCTCCGTTGGAGCG
GCCCGGCAGGAGGCAGCAGC

Downstream 100 bases:

>100_bases
CCCAACCGATCCCCCAATCCCGCCCAGGACAGGAAAACGAAATGACCCAAGCCCAGACCGCCGCCGTGCAACCCGCCGCG
ATCCCCGTGGCCGCCCCGGC

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MTAPLSVFVTGTDTEIGKTFVSAAMLHGFARHGLRAAALKPVAAGAYERDGVWRNEDADQLDAAANVALPPELRTPFLLK
APAAPHIVAAQEGVTLDLDTIVACHREALTRADVVVVEGVGGFRVPLNDTQDTADLAVALGLPVVLVVGVRLGCISHALL
TADAIRQRGLTLAGWVANHVDPAMSFADENVATIRDWLAREHRAPLIGRIAHMTPAAPESAAAMLDIAALVESLRTARR

Sequences:

>Translated_239_residues
MTAPLSVFVTGTDTEIGKTFVSAAMLHGFARHGLRAAALKPVAAGAYERDGVWRNEDADQLDAAANVALPPELRTPFLLK
APAAPHIVAAQEGVTLDLDTIVACHREALTRADVVVVEGVGGFRVPLNDTQDTADLAVALGLPVVLVVGVRLGCISHALL
TADAIRQRGLTLAGWVANHVDPAMSFADENVATIRDWLAREHRAPLIGRIAHMTPAAPESAAAMLDIAALVESLRTARR
>Mature_238_residues
TAPLSVFVTGTDTEIGKTFVSAAMLHGFARHGLRAAALKPVAAGAYERDGVWRNEDADQLDAAANVALPPELRTPFLLKA
PAAPHIVAAQEGVTLDLDTIVACHREALTRADVVVVEGVGGFRVPLNDTQDTADLAVALGLPVVLVVGVRLGCISHALLT
ADAIRQRGLTLAGWVANHVDPAMSFADENVATIRDWLAREHRAPLIGRIAHMTPAAPESAAAMLDIAALVESLRTARR

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=215, Percent_Identity=44.6511627906977, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI87081944, Length=223, Percent_Identity=37.219730941704, Blast_Score=136, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324385, Length=171, Percent_Identity=34.5029239766082, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 25189; Mature: 25058

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPLSVFVTGTDTEIGKTFVSAAMLHGFARHGLRAAALKPVAAGAYERDGVWRNEDADQ
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHCHHHCCCCCCCCCCCCCCHHH
LDAAANVALPPELRTPFLLKAPAAPHIVAAQEGVTLDLDTIVACHREALTRADVVVVEGV
HHHHCCCCCCCCCCCCEEEECCCCCCEEEECCCCEECHHHHHHHHHHHHHHCCEEEEECC
GGFRVPLNDTQDTADLAVALGLPVVLVVGVRLGCISHALLTADAIRQRGLTLAGWVANHV
CCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHH
DPAMSFADENVATIRDWLAREHRAPLIGRIAHMTPAAPESAAAMLDIAALVESLRTARR
HHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TAPLSVFVTGTDTEIGKTFVSAAMLHGFARHGLRAAALKPVAAGAYERDGVWRNEDADQ
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHCHHHCCCCCCCCCCCCCCHHH
LDAAANVALPPELRTPFLLKAPAAPHIVAAQEGVTLDLDTIVACHREALTRADVVVVEGV
HHHHCCCCCCCCCCCCEEEECCCCCCEEEECCCCEECHHHHHHHHHHHHHHCCEEEEECC
GGFRVPLNDTQDTADLAVALGLPVVLVVGVRLGCISHALLTADAIRQRGLTLAGWVANHV
CCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHH
DPAMSFADENVATIRDWLAREHRAPLIGRIAHMTPAAPESAAAMLDIAALVESLRTARR
HHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA