Click here to switch to the map view.

The map label for this gene is paaG [C]

Identifier: 116690929

GI number: 116690929

Start: 3215231

End: 3216058

Strand: Reverse

Name: paaG [C]

Synonym: Bcen2424_2911

Alternate gene names: 116690929

Gene position: 3216058-3215231 (Counterclockwise)

Preceding gene: 116690930

Following gene: 116690928

Centisome position: 92.31

GC content: 69.69

Gene sequence:

>828_bases
ATGGCCGATCTTGCCGCGTACGGCGGTTACGAAGCACTGAAGGTGACGCGCCGCGACCATGGCGTGCTCGACATCGTGAT
GAGCGGCGAGGGCGCGAACCGCAGCGGCCTCGCGACCGCGAACGCGCGCATGCATCGCGAGCTCGCCGACATCTGGCGCG
ACGTCGATCGCGATCCCGACACGCGCGTCGCGGTGATCCGCGGCGAAGGCAAGGGCTTTTCGGCGGGCGGCGATCTCGCG
CTCGTCGAGGAGATGGCGAACGATTTCGACGTGCGCGCCCGCGTGTGGCGCGAGGCGCGTGACCTCGTCTACAACGTAAT
CAACTGCAGCAAGCCGATCGTGTCGGCGATGCACGGCCCGGCCGTCGGCGCAGGGCTCGTCGCCGGGCTGCTCGCCGACA
TCTCGATCGCCGCGAAGGATGCGCGCATCATCGACGGCCATACGCGGCTCGGCGTCGCGGCCGGCGACCACGCGGCGATC
GTGTGGCCGCTCCTGTGCGGGATGGCGAAGGCGAAGTACTACCTGATGCTGTGCGAGCCCGTGAGCGGCGAGGAGGCCGA
GCGGATCGGGCTGGTCTCGCTCGCGGTCGAGCCGGCCGACCTGCTGCCGAAGGCATACGAAGTGGCCGAGCGGCTCGCGC
ACGGTTCGCAGTCGGCGATCCGCTGGACCAAGTACGCGCTGAACAACTGGCTGCGCATGGCCGGCCCGACCTTCGATACG
TCGCTCGCGCTCGAATTCATGGGTTTTTCGGGGCCCGACGTGCAGGAAGGCATCCGTTCGCTGCGCGAGCGGCGCCCGCC
CGCGTTCCCCGGCGACGCGCCGTTCTGA

Upstream 100 bases:

>100_bases
CCGGCTTCGGCCCGCGCGCCGGGTTTCGCCCGATGTTTGACCGCGCGGGCTTGGCTACACTCGATTCAAGCGTTCGAGCG
CCTCGAACAAGGAGCAGCAG

Downstream 100 bases:

>100_bases
CGTGCGCGCTATGATCGAACCACGCGCGGCTGCGCGACGCACAGCGGCCGCCTCGCTCCCCCAGTCAACCAGGATGCCCG
TATGACGACCGATGCCTCCG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MADLAAYGGYEALKVTRRDHGVLDIVMSGEGANRSGLATANARMHRELADIWRDVDRDPDTRVAVIRGEGKGFSAGGDLA
LVEEMANDFDVRARVWREARDLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADISIAAKDARIIDGHTRLGVAAGDHAAI
VWPLLCGMAKAKYYLMLCEPVSGEEAERIGLVSLAVEPADLLPKAYEVAERLAHGSQSAIRWTKYALNNWLRMAGPTFDT
SLALEFMGFSGPDVQEGIRSLRERRPPAFPGDAPF

Sequences:

>Translated_275_residues
MADLAAYGGYEALKVTRRDHGVLDIVMSGEGANRSGLATANARMHRELADIWRDVDRDPDTRVAVIRGEGKGFSAGGDLA
LVEEMANDFDVRARVWREARDLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADISIAAKDARIIDGHTRLGVAAGDHAAI
VWPLLCGMAKAKYYLMLCEPVSGEEAERIGLVSLAVEPADLLPKAYEVAERLAHGSQSAIRWTKYALNNWLRMAGPTFDT
SLALEFMGFSGPDVQEGIRSLRERRPPAFPGDAPF
>Mature_274_residues
ADLAAYGGYEALKVTRRDHGVLDIVMSGEGANRSGLATANARMHRELADIWRDVDRDPDTRVAVIRGEGKGFSAGGDLAL
VEEMANDFDVRARVWREARDLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADISIAAKDARIIDGHTRLGVAAGDHAAIV
WPLLCGMAKAKYYLMLCEPVSGEEAERIGLVSLAVEPADLLPKAYEVAERLAHGSQSAIRWTKYALNNWLRMAGPTFDTS
LALEFMGFSGPDVQEGIRSLRERRPPAFPGDAPF

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=159, Percent_Identity=33.9622641509434, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787660, Length=241, Percent_Identity=30.2904564315353, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787659, Length=265, Percent_Identity=29.0566037735849, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI221142681, Length=212, Percent_Identity=29.7169811320755, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788597, Length=263, Percent_Identity=23.574144486692, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17534483, Length=230, Percent_Identity=28.695652173913, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=216, Percent_Identity=26.3888888888889, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=231, Percent_Identity=26.4069264069264, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=237, Percent_Identity=26.1603375527426, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17540306, Length=259, Percent_Identity=25.8687258687259, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24653139, Length=286, Percent_Identity=27.6223776223776, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24654903, Length=200, Percent_Identity=24.5, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922422, Length=262, Percent_Identity=25.9541984732824, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI20129971, Length=233, Percent_Identity=25.3218884120172, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653477, Length=233, Percent_Identity=25.3218884120172, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29656; Mature: 29525

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLAAYGGYEALKVTRRDHGVLDIVMSGEGANRSGLATANARMHRELADIWRDVDRDPD
CCCCCHHCCHHHEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
TRVAVIRGEGKGFSAGGDLALVEEMANDFDVRARVWREARDLVYNVINCSKPIVSAMHGP
CEEEEEEECCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
AVGAGLVAGLLADISIAAKDARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYLMLCEP
CHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHCEEEEEEECC
VSGEEAERIGLVSLAVEPADLLPKAYEVAERLAHGSQSAIRWTKYALNNWLRMAGPTFDT
CCCCCHHHEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCH
SLALEFMGFSGPDVQEGIRSLRERRPPAFPGDAPF
HHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ADLAAYGGYEALKVTRRDHGVLDIVMSGEGANRSGLATANARMHRELADIWRDVDRDPD
CCCCHHCCHHHEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
TRVAVIRGEGKGFSAGGDLALVEEMANDFDVRARVWREARDLVYNVINCSKPIVSAMHGP
CEEEEEEECCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
AVGAGLVAGLLADISIAAKDARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYLMLCEP
CHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHCEEEEEEECC
VSGEEAERIGLVSLAVEPADLLPKAYEVAERLAHGSQSAIRWTKYALNNWLRMAGPTFDT
CCCCCHHHEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCH
SLALEFMGFSGPDVQEGIRSLRERRPPAFPGDAPF
HHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA