| Definition | Burkholderia cenocepacia HI2424 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008542 |
| Length | 3,483,902 |
Click here to switch to the map view.
The map label for this gene is phbB [H]
Identifier: 116690791
GI number: 116690791
Start: 3066417
End: 3067211
Strand: Reverse
Name: phbB [H]
Synonym: Bcen2424_2771
Alternate gene names: 116690791
Gene position: 3067211-3066417 (Counterclockwise)
Preceding gene: 116690792
Following gene: 116690790
Centisome position: 88.04
GC content: 62.89
Gene sequence:
>795_bases ATGCCGTCGCCCCGCCTTTCATCGATTACTTTTTTGTCGGTAATTCATAGTATGACTAAGCGAATCGCAGTTGTGACAGG TGGGATGGGCGGCCTCGGCGAAGCGGTCAGCATCCGGTTGAACGACGCGGGTCACCGGGTAGTCGTCACGTATTCGCCGA ACAATGCCGGCGCGGACCGCTGGCTGACCGAGATGCATGCGGCCGGCCGCGAATTCCATGCGTATCCGGTGGACGTGGCC GATCACGACTCGTGCCAGCAATGCATCGAGAAGATCGTGCGCGACGTCGGCCCGGTCGACATTCTCGTGAACAATGCGGG CATCACGCGCGACATGACGCTGCGCAAGCTCGACAAGGTCAACTGGGATGCGGTGATCCGCACCAACCTCGATTCCGTGT TCAACATGACGAAACCGGTCTGCGACGGCATGGTCGAGCGCGGCTGGGGCCGCATCGTCAACATCTCGTCGGTGAACGGC TCGAAAGGGTCGGTCGGCCAGACCAACTACGCGGCCGCGAAAGCCGGCATGCACGGGTTCACGAAATCGCTTGCGCTCGA GGTCGCGCGCAAGGGCGTGACGGTGAACACGGTGTCGCCGGGCTATCTCGCGACGAAGATGGTCACCGCGATTCCGCAGG ACATCCTCGACACGAAGATCCTCCCGCAGATTCCGGCGGGCCGGCTCGGCAAGCCCGAGGAGGTCGCGGCGCTGGTCGCT TACCTGTGCTCGGAGGAGGCCGGCTTCGTGACGGGCTCCAACATCGCGATCAACGGCGGTCAGCACATGCACTGA
Upstream 100 bases:
>100_bases CGCAAGACAGGCAGTCAATAACACGCGCGAGGTGCCGGTGCGTGCCGCGTCCGCGACGCGGGCGGCTGCGCATCGAAGCG GTGGGGCGGCAGCAGGTGCG
Downstream 100 bases:
>100_bases CGCGCGGCGGCCCGCAGGGCGTGCGCGCCCGGCGGGCCGCGTTCCCCACTATCCCGCGCCGGAGCGGCGGCAGACGCGCC GCTTCGGCCTCGCATTCCGG
Product: acetoacetyl-CoA reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 264; Mature: 263
Protein sequence:
>264_residues MPSPRLSSITFLSVIHSMTKRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNAGADRWLTEMHAAGREFHAYPVDVA DHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMTKPVCDGMVERGWGRIVNISSVNG SKGSVGQTNYAAAKAGMHGFTKSLALEVARKGVTVNTVSPGYLATKMVTAIPQDILDTKILPQIPAGRLGKPEEVAALVA YLCSEEAGFVTGSNIAINGGQHMH
Sequences:
>Translated_264_residues MPSPRLSSITFLSVIHSMTKRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNAGADRWLTEMHAAGREFHAYPVDVA DHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMTKPVCDGMVERGWGRIVNISSVNG SKGSVGQTNYAAAKAGMHGFTKSLALEVARKGVTVNTVSPGYLATKMVTAIPQDILDTKILPQIPAGRLGKPEEVAALVA YLCSEEAGFVTGSNIAINGGQHMH >Mature_263_residues PSPRLSSITFLSVIHSMTKRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNAGADRWLTEMHAAGREFHAYPVDVAD HDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMTKPVCDGMVERGWGRIVNISSVNGS KGSVGQTNYAAAKAGMHGFTKSLALEVARKGVTVNTVSPGYLATKMVTAIPQDILDTKILPQIPAGRLGKPEEVAALVAY LCSEEAGFVTGSNIAINGGQHMH
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=38.6454183266932, Blast_Score=161, Evalue=7e-40, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=33.7448559670782, Blast_Score=128, Evalue=4e-30, Organism=Homo sapiens, GI4504505, Length=237, Percent_Identity=32.0675105485232, Blast_Score=118, Evalue=6e-27, Organism=Homo sapiens, GI19923817, Length=265, Percent_Identity=30.188679245283, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=28.9795918367347, Blast_Score=112, Evalue=4e-25, Organism=Homo sapiens, GI5031737, Length=264, Percent_Identity=29.5454545454545, Blast_Score=98, Evalue=8e-21, Organism=Homo sapiens, GI4758504, Length=262, Percent_Identity=30.9160305343511, Blast_Score=98, Evalue=9e-21, Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=30.2040816326531, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI66933014, Length=200, Percent_Identity=31.5, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI4503301, Length=198, Percent_Identity=28.7878787878788, Blast_Score=91, Evalue=8e-19, Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=26.2096774193548, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=28.2258064516129, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI59889578, Length=193, Percent_Identity=30.0518134715026, Blast_Score=85, Evalue=9e-17, Organism=Homo sapiens, GI7657478, Length=190, Percent_Identity=31.0526315789474, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI83715985, Length=262, Percent_Identity=29.3893129770992, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI20149619, Length=202, Percent_Identity=33.6633663366337, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=30.8457711442786, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI4503817, Length=224, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI33667109, Length=209, Percent_Identity=29.6650717703349, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI7705855, Length=192, Percent_Identity=34.375, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI40807363, Length=220, Percent_Identity=26.8181818181818, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI210032110, Length=192, Percent_Identity=25.5208333333333, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI226371731, Length=214, Percent_Identity=31.7757009345794, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI7706318, Length=196, Percent_Identity=25.5102040816327, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=27.8688524590164, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI142976729, Length=245, Percent_Identity=23.6734693877551, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=45.2674897119342, Blast_Score=200, Evalue=1e-52, Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=31.2, Blast_Score=136, Evalue=2e-33, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=34.765625, Blast_Score=135, Evalue=3e-33, Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=32.3886639676113, Blast_Score=134, Evalue=7e-33, Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=30.2904564315353, Blast_Score=123, Evalue=1e-29, Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=29.1497975708502, Blast_Score=120, Evalue=1e-28, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=33.469387755102, Blast_Score=114, Evalue=5e-27, Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=32.9268292682927, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=27.4590163934426, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=27.8225806451613, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=27.6, Blast_Score=92, Evalue=5e-20, Organism=Escherichia coli, GI1789057, Length=262, Percent_Identity=30.5343511450382, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=30.939226519337, Blast_Score=82, Evalue=4e-17, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=42.0408163265306, Blast_Score=171, Evalue=3e-43, Organism=Caenorhabditis elegans, GI17555706, Length=263, Percent_Identity=37.6425855513308, Blast_Score=160, Evalue=5e-40, Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=31.9838056680162, Blast_Score=122, Evalue=2e-28, Organism=Caenorhabditis elegans, GI17568967, Length=244, Percent_Identity=31.9672131147541, Blast_Score=120, Evalue=8e-28, Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=30.4, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=30.4182509505703, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI193203117, Length=204, Percent_Identity=33.8235294117647, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI193203115, Length=196, Percent_Identity=34.6938775510204, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=29.1666666666667, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17538182, Length=268, Percent_Identity=28.7313432835821, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=30.078125, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=27.3809523809524, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562990, Length=254, Percent_Identity=27.9527559055118, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=29.4117647058824, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562906, Length=258, Percent_Identity=27.5193798449612, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=28.1368821292776, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=28.030303030303, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=27.3408239700375, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=25.2830188679245, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=26.5151515151515, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=26.0377358490566, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=25.4752851711027, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17536651, Length=257, Percent_Identity=29.1828793774319, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=28.4584980237154, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=26.4925373134328, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=27.5303643724696, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17564282, Length=194, Percent_Identity=28.8659793814433, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=27.5510204081633, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=28.4644194756554, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=26.8, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=27.3408239700375, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=26.9230769230769, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=26.2357414448669, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17561272, Length=198, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=3e-15, Organism=Saccharomyces cerevisiae, GI6322861, Length=241, Percent_Identity=31.9502074688797, Blast_Score=114, Evalue=1e-26, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=26, Blast_Score=75, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6320089, Length=209, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-12, Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=34.5528455284553, Blast_Score=138, Evalue=3e-33, Organism=Drosophila melanogaster, GI18859837, Length=236, Percent_Identity=36.864406779661, Blast_Score=120, Evalue=6e-28, Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=31.640625, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=30.1652892561983, Blast_Score=116, Evalue=2e-26, Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=31.8548387096774, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=31.3725490196078, Blast_Score=111, Evalue=5e-25, Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=30.2325581395349, Blast_Score=105, Evalue=4e-23, Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=30.2040816326531, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI17737361, Length=259, Percent_Identity=29.7297297297297, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI24644337, Length=184, Percent_Identity=35.3260869565217, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI21358495, Length=200, Percent_Identity=31, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24649181, Length=204, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24665243, Length=198, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI221331218, Length=198, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI21355631, Length=169, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI24665247, Length=199, Percent_Identity=33.1658291457286, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI221331216, Length=199, Percent_Identity=33.1658291457286, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI24581726, Length=158, Percent_Identity=29.746835443038, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI161076933, Length=202, Percent_Identity=31.6831683168317, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24584748, Length=202, Percent_Identity=31.6831683168317, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI28574402, Length=195, Percent_Identity=29.7435897435897, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI24584744, Length=195, Percent_Identity=29.7435897435897, Blast_Score=65, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011283 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.36 [H]
Molecular weight: Translated: 28194; Mature: 28063
Theoretical pI: Translated: 8.34; Mature: 8.34
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 3.8 %Met (Translated Protein) 5.3 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 3.4 %Met (Mature Protein) 4.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPSPRLSSITFLSVIHSMTKRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNAGADR CCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEECCCCCEEEEEECCCCCCHHH WLTEMHAAGREFHAYPVDVADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKV HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCC NWDAVIRTNLDSVFNMTKPVCDGMVERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGF CCCEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH TKSLALEVARKGVTVNTVSPGYLATKMVTAIPQDILDTKILPQIPAGRLGKPEEVAALVA HHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH YLCSEEAGFVTGSNIAINGGQHMH HHHCCCCCEEECCCEEECCCCCCC >Mature Secondary Structure PSPRLSSITFLSVIHSMTKRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNAGADR CCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEECCCCCEEEEEECCCCCCHHH WLTEMHAAGREFHAYPVDVADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKV HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCC NWDAVIRTNLDSVFNMTKPVCDGMVERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGF CCCEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH TKSLALEVARKGVTVNTVSPGYLATKMVTAIPQDILDTKILPQIPAGRLGKPEEVAALVA HHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH YLCSEEAGFVTGSNIAINGGQHMH HHHCCCCCEEECCCEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2670935 [H]