Click here to switch to the map view.

The map label for this gene is fabF [H]

Identifier: 116690786

GI number: 116690786

Start: 3063077

End: 3064348

Strand: Direct

Name: fabF [H]

Synonym: Bcen2424_2766

Alternate gene names: 116690786

Gene position: 3063077-3064348 (Clockwise)

Preceding gene: 116690785

Following gene: 116690787

Centisome position: 87.92

GC content: 73.11

Gene sequence:

>1272_bases
GTGCCAGCCCTGCTGCGGCGCCCGTTCCGGCCACCGGATGCGACCCTCGTGAACCCTCTCCTGCTCTCGCACTTCACCGC
CACCAGCTGCATCGGCCGCGGCCTCGACGCGACCCTCGATGCGCTGCGCCACGCCCGCAGCGGCCTCGTGCCGTGCAACT
TCGAGCGTGCGGATCTCGACACGTGGATCGGTGCGGTGAACGGCGTCGATGCGCAGCCCGTGCGCGCCGATCTCGCCGAC
TTCGACTGCCGCAACAACCGCCTCGCGCAACTCGGCCTGACGCAGGACGGCTTCGACGCGCGCGTCGCGGCGGCGGTCGC
GCGCTACGGCGCCGCACGCGTCGGCGTGTTCGTCGGCACGAGCACGGCCGGCATCCTCGAAACCGAACGCGCGTACCAGC
GCCGCGATCCGGCGAGCGGCGCGCTGCCCGCCGACTTCCGCTACGCGCACACGCACAACCCGTATTCGCCGGCCGCGTTC
GTGCGCGCGTATTTCGCGCTGCGCGGGCCGGCGATGGCGATCTCGTCCGCATGCTCGTCGGGCGCGAAGGTGTTCGGCTC
CGCGCGCCGCATGATCGAGGCCGGGCTGATCGACGCGGCCGTCGTCGGCGGCGTCGATTCGCTGTGCCTGACCACGCTGT
ACGGCTTCAATTCGCTCGAACTGCTGTCGCGCCAGCCATGCCGGCCGTTCGACGTCGCGCGCGACGGCATCTCGATCGGC
GAGGCCGCCGCGTTCGCGCTCGTCGAGCGCGTCCCTGCCCCGCCCGCCACGCTCGACGCCGACGCGATCCTGCTGCTCGG
CATCGGCGAATCGAGCGACGCGCATCACATGTCGTCGCCGCATCCGGAAGGGCTCGGCGCGCGCGCCGCGATCGAGCAGG
CGCTCGCATCCGCCGGCCTCGACGCGCACGACATCGACTACGTGAACCTGCACGGCACCGCGACGCCGAGCAACGACGCA
GCGGAAAGCCGCGCGCTCGGTGCGCTGTTCGCCCGCACGCCGTGCAGCTCGACGAAGGGCGCGACCGGCCACACGCTCGG
CGCGGCCGGCGCGCTGGAGGCGATCGTCGCCGCGCTCGCGCTGCGCGAGCAGTTCGTGCCGGCCGGCGTCAACACGACGC
AGCCCGACCCGGCGCTCGTCGCCGATTACGTGCTCGCGAGCCGCGACACGCGCGTGCGCGCCGTCCTCTCCAATTCGTTC
GGCTTCGGCGGCACGAATTGCAGCCTGATCCTCGGCCGCGCCCAGCGCGTGGCCGGCCGCGCCCGTCGTTGA

Upstream 100 bases:

>100_bases
GCCCTGGACCACCCTGCGCGCGGCGCTGGCACCCGAACCGCCCGGCCAGCTGGGCGTTCCGGCACCCCCGTTTGATAAAA
TCTGACCTCGAACGGCGCGC

Downstream 100 bases:

>100_bases
GGCCCGCCATGACACTCACCGCCTTCATCGAAAGCATTGGCCTCGTCGGGCCGGGATTGACCGACTGGCCGCATGCGGCC
GACGTGCTCGCGGGCCGCAC

Product: 3-oxoacyl-(acyl carrier protein) synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MPALLRRPFRPPDATLVNPLLLSHFTATSCIGRGLDATLDALRHARSGLVPCNFERADLDTWIGAVNGVDAQPVRADLAD
FDCRNNRLAQLGLTQDGFDARVAAAVARYGAARVGVFVGTSTAGILETERAYQRRDPASGALPADFRYAHTHNPYSPAAF
VRAYFALRGPAMAISSACSSGAKVFGSARRMIEAGLIDAAVVGGVDSLCLTTLYGFNSLELLSRQPCRPFDVARDGISIG
EAAAFALVERVPAPPATLDADAILLLGIGESSDAHHMSSPHPEGLGARAAIEQALASAGLDAHDIDYVNLHGTATPSNDA
AESRALGALFARTPCSSTKGATGHTLGAAGALEAIVAALALREQFVPAGVNTTQPDPALVADYVLASRDTRVRAVLSNSF
GFGGTNCSLILGRAQRVAGRARR

Sequences:

>Translated_423_residues
MPALLRRPFRPPDATLVNPLLLSHFTATSCIGRGLDATLDALRHARSGLVPCNFERADLDTWIGAVNGVDAQPVRADLAD
FDCRNNRLAQLGLTQDGFDARVAAAVARYGAARVGVFVGTSTAGILETERAYQRRDPASGALPADFRYAHTHNPYSPAAF
VRAYFALRGPAMAISSACSSGAKVFGSARRMIEAGLIDAAVVGGVDSLCLTTLYGFNSLELLSRQPCRPFDVARDGISIG
EAAAFALVERVPAPPATLDADAILLLGIGESSDAHHMSSPHPEGLGARAAIEQALASAGLDAHDIDYVNLHGTATPSNDA
AESRALGALFARTPCSSTKGATGHTLGAAGALEAIVAALALREQFVPAGVNTTQPDPALVADYVLASRDTRVRAVLSNSF
GFGGTNCSLILGRAQRVAGRARR
>Mature_422_residues
PALLRRPFRPPDATLVNPLLLSHFTATSCIGRGLDATLDALRHARSGLVPCNFERADLDTWIGAVNGVDAQPVRADLADF
DCRNNRLAQLGLTQDGFDARVAAAVARYGAARVGVFVGTSTAGILETERAYQRRDPASGALPADFRYAHTHNPYSPAAFV
RAYFALRGPAMAISSACSSGAKVFGSARRMIEAGLIDAAVVGGVDSLCLTTLYGFNSLELLSRQPCRPFDVARDGISIGE
AAAFALVERVPAPPATLDADAILLLGIGESSDAHHMSSPHPEGLGARAAIEQALASAGLDAHDIDYVNLHGTATPSNDAA
ESRALGALFARTPCSSTKGATGHTLGAAGALEAIVAALALREQFVPAGVNTTQPDPALVADYVLASRDTRVRAVLSNSFG
FGGTNCSLILGRAQRVAGRARR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=266, Percent_Identity=40.6015037593985, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI223972627, Length=147, Percent_Identity=44.8979591836735, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI41872631, Length=266, Percent_Identity=28.9473684210526, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1787337, Length=269, Percent_Identity=40.1486988847584, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1788663, Length=257, Percent_Identity=34.2412451361868, Blast_Score=126, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71983541, Length=268, Percent_Identity=34.7014925373134, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI71983535, Length=258, Percent_Identity=34.8837209302326, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI212642053, Length=336, Percent_Identity=27.9761904761905, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17550940, Length=309, Percent_Identity=25.5663430420712, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320904, Length=278, Percent_Identity=36.3309352517986, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24644341, Length=321, Percent_Identity=35.8255451713396, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24581345, Length=325, Percent_Identity=26.7692307692308, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19920632, Length=328, Percent_Identity=26.219512195122, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221330659, Length=328, Percent_Identity=26.219512195122, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 44094; Mature: 43963

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALLRRPFRPPDATLVNPLLLSHFTATSCIGRGLDATLDALRHARSGLVPCNFERADLD
CCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHH
TWIGAVNGVDAQPVRADLADFDCRNNRLAQLGLTQDGFDARVAAAVARYGAARVGVFVGT
HHHHHCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCHHEEEEECC
STAGILETERAYQRRDPASGALPADFRYAHTHNPYSPAAFVRAYFALRGPAMAISSACSS
CCCCHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
GAKVFGSARRMIEAGLIDAAVVGGVDSLCLTTLYGFNSLELLSRQPCRPFDVARDGISIG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHCCCCHH
EAAAFALVERVPAPPATLDADAILLLGIGESSDAHHMSSPHPEGLGARAAIEQALASAGL
HHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
DAHDIDYVNLHGTATPSNDAAESRALGALFARTPCSSTKGATGHTLGAAGALEAIVAALA
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LREQFVPAGVNTTQPDPALVADYVLASRDTRVRAVLSNSFGFGGTNCSLILGRAQRVAGR
HHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHCCCCCCCCCHHEEEHHHHHHHHC
ARR
CCC
>Mature Secondary Structure 
PALLRRPFRPPDATLVNPLLLSHFTATSCIGRGLDATLDALRHARSGLVPCNFERADLD
CCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHH
TWIGAVNGVDAQPVRADLADFDCRNNRLAQLGLTQDGFDARVAAAVARYGAARVGVFVGT
HHHHHCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCHHEEEEECC
STAGILETERAYQRRDPASGALPADFRYAHTHNPYSPAAFVRAYFALRGPAMAISSACSS
CCCCHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
GAKVFGSARRMIEAGLIDAAVVGGVDSLCLTTLYGFNSLELLSRQPCRPFDVARDGISIG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHCCCCHH
EAAAFALVERVPAPPATLDADAILLLGIGESSDAHHMSSPHPEGLGARAAIEQALASAGL
HHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
DAHDIDYVNLHGTATPSNDAAESRALGALFARTPCSSTKGATGHTLGAAGALEAIVAALA
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LREQFVPAGVNTTQPDPALVADYVLASRDTRVRAVLSNSFGFGGTNCSLILGRAQRVAGR
HHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHCCCCCCCCCHHEEEHHHHHHHHC
ARR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12704232 [H]