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The map label for this gene is lptD

Identifier: 116690731

GI number: 116690731

Start: 3002024

End: 3004384

Strand: Reverse

Name: lptD

Synonym: Bcen2424_2711

Alternate gene names: 116690731

Gene position: 3004384-3002024 (Counterclockwise)

Preceding gene: 116690734

Following gene: 116690730

Centisome position: 86.24

GC content: 66.03

Gene sequence:

>2361_bases
ATGCCGCCCAAACCGCTATTCCCGAATGTTTTCCCCGGTGACGGGGCGCCGCGCAAACGGCGGCTCGCGCTCGCGCTCCT
GGCCGTGCCCGGCCTCGTGCCGGCCGTGTCGTATGCGCAGCTGTCGGGCGCGGCTGCGCAGCCGCAGCCGCTCGACTCGC
CGTGGGATCTGCGTCTCGCGCCCCAGCTCGAGGATCATCCGCTGAAGGACGGCGCGAAGCCGGCCGCCTTCGTGATCGCC
GACCATACGAGCGGCACCGCCGAGCAGGATCTCGCCGCGAAGGGCTCGGCCGAGCTGCGGCGCGGCGACGCCGTCGTGAA
GGCCGACGCGATCCACTACGATCAGGATACCGACATGGCCGATGCGTACGGCCAGGTCAAGGTGATCAATGGCGGCACGT
CGTTCGCCGGCCCCGAGGCGCACCTGAAGATCGAGGCGAACCAGGGCTTCATGACCGCGCCGAAGTATCACTTCAACGTG
ACGGGCGGCTCGGGCAGCGCGGAGCGTGTCGACATGGTCGACAACGAGCGCTCGGTGTTCGTCAACGGCACGTACACGGC
GTGCCAGTGCTCGACGAACCCCGCTTGGTACATCAAGGGCAGCCGCTTCGATTTCGATACGGGCGCCGACGAAGGCACCG
CGCGCAACGGCGTGCTGTTCTTCCAGGGCGTGCCGATCTTCGCGAGCCCGTGGATGACGTTCCCGCTGTCGGGCGAGCGG
CGCAGCGGCCTGCTGCCGCCGACGTTCTCGATGAACTCGAGCAACGGCTTCGAGCTGTCGCTGCCGTACTACTTCAACAT
CGCGCCGAACCGCGACCTGACGCTCACGCCGCGCATCATCTCGCGGCGCGGCGTGATGACCGAAGCGACGTTCCGCTATC
TGTCGCCGTCGTATTCGGGCACGTTTACGGCCAATTACCTGCCGGATGACCGGCTCGCGCACCGCAACCGCTACGCGATC
TACTGGCAGCACCAGCAGAACTTCGGCGGCGGCTTCGGCGGCTACGTCTATTACAACAAGGTCTCGGACAACACGTATCC
CGAAGACCTCGGCTCGGCGAACCAGTTCATCAACGGGACGCAGACGCTGTACCAGCAGGAAGCGGGCCTCACGTACAACA
ACGGCCCGTGGTCGGTGCTCGCGCGCTACCAGCACTGGCAGACGCTGCCGCCGTCGATCGCGCCGTACAGCCGCGAGCCG
CAGTTGAACGTGAAGTACACGAAGTACAACGTCGGCGGGTTCGACTTCGGCGCGGAAGCCGACTATTCGCGGTTCCGCAT
CACGACCGCCGATGCGACCGAAGGCGACCGGATCGTCTTCAACCCGTACATCTCGTACGGCGTGTACGGCCCCGGCTACT
TCGTCGTGCCGAAGGTCCAGTACCACTTCGCGTCGTACGACCTGAACTACCTGTCGTCGACCACGCCGAACAGCCCGAAG
CGCTTCACCGAGTCGATCCCGACCGTGACCTTCGACACGGGCCTGATCTTCGATCGCTCGGTGCGCCTGTTCGGCCAGGA
CTTCATCCAGACCCTCGAGCCGCGCCTGTACTACGTGTACACGCCGTATCGCGACCAGTCGAACGCGCCGCTGTTCGACA
CCGCGGAATCGGACTTCGGCCTCGCGGAAATCTACCAGCCGAACACGTTCGTCGGGAACGACCGGATCGCCGATGCGAAC
CGGATCACGGCCGGCCTGACGTCGCGCTTCATCGATCCGCGCACCGGCGACGAGCGCGCGCGCTTCGTGATCGCGCAGCA
GTACTACTTCGCCGATCAGCGCGTCACGCTGAACCCCGGGCAGGCCGCCGTGCTGGCGCGCCACTCCGACCTGATCGTCG
GCGCCGCGCTGAAGCTCGGCTCGGGCTTCATGTCCGAGACGGCATTCCAGTACAACCAGAACAACAACCAGCTCGTGAAG
TCGAGCGTCGGTTTCGGCTACAGCCCGGGCGAGCGCCGCGTGATCAACGTCGGCTACCGCTATACGCGTGCGAACACCAC
CCTCGACAACCAGCCGATCAACCAGTTCCTGGTGTCCGCGCAATGGCCGCTCACGCGCCGCCTGTATGCGATCGGCCGTT
TCAACTACGACCTCGCCGGAGATCGCGTGGTCGACGGTCTGGTCGGCTTACAATACGACGCGGATTGCTGGGCGCTCGGG
GTCGGGGTGCAGCGGGCCGCGAACGGCATCAATTCGTCGGGACAGCAGAACTCGTCGACGCGATTCATGATGCAGCTGAC
GCTCAAGGGCCTGTCGACCGTCGACAACGGCCTCGTGTCCGCATTCCGCGCCGGGGTGCCGGGCTACACGCCGTTGCCGC
CGCCGCCGCCGCCGATGTCCCGCTTCAGCAACTACGAGTAA

Upstream 100 bases:

>100_bases
CCGGTTTGCGAAGAGCCGCAGTCGCGGCTCGACGGCGCGGCCGCCGCGCGCGAGGTGCCGTGCAGGCGCGGTTGACAAGG
GGCGATTCGCCAAACGATAG

Downstream 100 bases:

>100_bases
CGCCGGCATGTCTGCACCGGTCAGCACGATTTCAATGGAGTTCCAGTGGCAATGAAGAAAACCCTTCGTTTCGCGGCAGT
CGTGTCCAGCCTCGCCGCGT

Product: organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein

Number of amino acids: Translated: 786; Mature: 785

Protein sequence:

>786_residues
MPPKPLFPNVFPGDGAPRKRRLALALLAVPGLVPAVSYAQLSGAAAQPQPLDSPWDLRLAPQLEDHPLKDGAKPAAFVIA
DHTSGTAEQDLAAKGSAELRRGDAVVKADAIHYDQDTDMADAYGQVKVINGGTSFAGPEAHLKIEANQGFMTAPKYHFNV
TGGSGSAERVDMVDNERSVFVNGTYTACQCSTNPAWYIKGSRFDFDTGADEGTARNGVLFFQGVPIFASPWMTFPLSGER
RSGLLPPTFSMNSSNGFELSLPYYFNIAPNRDLTLTPRIISRRGVMTEATFRYLSPSYSGTFTANYLPDDRLAHRNRYAI
YWQHQQNFGGGFGGYVYYNKVSDNTYPEDLGSANQFINGTQTLYQQEAGLTYNNGPWSVLARYQHWQTLPPSIAPYSREP
QLNVKYTKYNVGGFDFGAEADYSRFRITTADATEGDRIVFNPYISYGVYGPGYFVVPKVQYHFASYDLNYLSSTTPNSPK
RFTESIPTVTFDTGLIFDRSVRLFGQDFIQTLEPRLYYVYTPYRDQSNAPLFDTAESDFGLAEIYQPNTFVGNDRIADAN
RITAGLTSRFIDPRTGDERARFVIAQQYYFADQRVTLNPGQAAVLARHSDLIVGAALKLGSGFMSETAFQYNQNNNQLVK
SSVGFGYSPGERRVINVGYRYTRANTTLDNQPINQFLVSAQWPLTRRLYAIGRFNYDLAGDRVVDGLVGLQYDADCWALG
VGVQRAANGINSSGQQNSSTRFMMQLTLKGLSTVDNGLVSAFRAGVPGYTPLPPPPPPMSRFSNYE

Sequences:

>Translated_786_residues
MPPKPLFPNVFPGDGAPRKRRLALALLAVPGLVPAVSYAQLSGAAAQPQPLDSPWDLRLAPQLEDHPLKDGAKPAAFVIA
DHTSGTAEQDLAAKGSAELRRGDAVVKADAIHYDQDTDMADAYGQVKVINGGTSFAGPEAHLKIEANQGFMTAPKYHFNV
TGGSGSAERVDMVDNERSVFVNGTYTACQCSTNPAWYIKGSRFDFDTGADEGTARNGVLFFQGVPIFASPWMTFPLSGER
RSGLLPPTFSMNSSNGFELSLPYYFNIAPNRDLTLTPRIISRRGVMTEATFRYLSPSYSGTFTANYLPDDRLAHRNRYAI
YWQHQQNFGGGFGGYVYYNKVSDNTYPEDLGSANQFINGTQTLYQQEAGLTYNNGPWSVLARYQHWQTLPPSIAPYSREP
QLNVKYTKYNVGGFDFGAEADYSRFRITTADATEGDRIVFNPYISYGVYGPGYFVVPKVQYHFASYDLNYLSSTTPNSPK
RFTESIPTVTFDTGLIFDRSVRLFGQDFIQTLEPRLYYVYTPYRDQSNAPLFDTAESDFGLAEIYQPNTFVGNDRIADAN
RITAGLTSRFIDPRTGDERARFVIAQQYYFADQRVTLNPGQAAVLARHSDLIVGAALKLGSGFMSETAFQYNQNNNQLVK
SSVGFGYSPGERRVINVGYRYTRANTTLDNQPINQFLVSAQWPLTRRLYAIGRFNYDLAGDRVVDGLVGLQYDADCWALG
VGVQRAANGINSSGQQNSSTRFMMQLTLKGLSTVDNGLVSAFRAGVPGYTPLPPPPPPMSRFSNYE
>Mature_785_residues
PPKPLFPNVFPGDGAPRKRRLALALLAVPGLVPAVSYAQLSGAAAQPQPLDSPWDLRLAPQLEDHPLKDGAKPAAFVIAD
HTSGTAEQDLAAKGSAELRRGDAVVKADAIHYDQDTDMADAYGQVKVINGGTSFAGPEAHLKIEANQGFMTAPKYHFNVT
GGSGSAERVDMVDNERSVFVNGTYTACQCSTNPAWYIKGSRFDFDTGADEGTARNGVLFFQGVPIFASPWMTFPLSGERR
SGLLPPTFSMNSSNGFELSLPYYFNIAPNRDLTLTPRIISRRGVMTEATFRYLSPSYSGTFTANYLPDDRLAHRNRYAIY
WQHQQNFGGGFGGYVYYNKVSDNTYPEDLGSANQFINGTQTLYQQEAGLTYNNGPWSVLARYQHWQTLPPSIAPYSREPQ
LNVKYTKYNVGGFDFGAEADYSRFRITTADATEGDRIVFNPYISYGVYGPGYFVVPKVQYHFASYDLNYLSSTTPNSPKR
FTESIPTVTFDTGLIFDRSVRLFGQDFIQTLEPRLYYVYTPYRDQSNAPLFDTAESDFGLAEIYQPNTFVGNDRIADANR
ITAGLTSRFIDPRTGDERARFVIAQQYYFADQRVTLNPGQAAVLARHSDLIVGAALKLGSGFMSETAFQYNQNNNQLVKS
SVGFGYSPGERRVINVGYRYTRANTTLDNQPINQFLVSAQWPLTRRLYAIGRFNYDLAGDRVVDGLVGLQYDADCWALGV
GVQRAANGINSSGQQNSSTRFMMQLTLKGLSTVDNGLVSAFRAGVPGYTPLPPPPPPMSRFSNYE

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family

Homologues:

Organism=Escherichia coli, GI1786239, Length=775, Percent_Identity=27.0967741935484, Blast_Score=260, Evalue=2e-70,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): LPTD_BURCA (Q1BTQ5)

Other databases:

- EMBL:   CP000378
- RefSeq:   YP_621973.1
- STRING:   Q1BTQ5
- GeneID:   4091109
- GenomeReviews:   CP000378_GR
- KEGG:   bcn:Bcen_2099
- eggNOG:   COG1452
- HOGENOM:   HBG701380
- OMA:   FPLSGAR
- ProtClustDB:   CLSK896578
- BioCyc:   BCEN331271:BCEN_2099-MONOMER
- HAMAP:   MF_01411
- InterPro:   IPR020889
- InterPro:   IPR007543

Pfam domain/function: PF04453 OstA_C

EC number: NA

Molecular weight: Translated: 86937; Mature: 86806

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPKPLFPNVFPGDGAPRKRRLALALLAVPGLVPAVSYAQLSGAAAQPQPLDSPWDLRLA
CCCCCCCCCCCCCCCCCCHHHHEEEEHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEC
PQLEDHPLKDGAKPAAFVIADHTSGTAEQDLAAKGSAELRRGDAVVKADAIHYDQDTDMA
CCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCHHHCCCEEEEEEEEECCCCCCHH
DAYGQVKVINGGTSFAGPEAHLKIEANQGFMTAPKYHFNVTGGSGSAERVDMVDNERSVF
HCCCEEEEEECCCCCCCCCEEEEEECCCCEEECCEEEEEEECCCCCCCEEEEECCCCEEE
VNGTYTACQCSTNPAWYIKGSRFDFDTGADEGTARNGVLFFQGVPIFASPWMTFPLSGER
EECCEEEEEECCCCEEEEECCEECCCCCCCCCCCCCCEEEEECCCEEECCCEEECCCCCC
RSGLLPPTFSMNSSNGFELSLPYYFNIAPNRDLTLTPRIISRRGVMTEATFRYLSPSYSG
CCCCCCCCEECCCCCCEEEECCEEEEECCCCCEEECHHHHHCCCCEEHHHHHHCCCCCCC
TFTANYLPDDRLAHRNRYAIYWQHQQNFGGGFGGYVYYNKVSDNTYPEDLGSANQFINGT
EEEECCCCCHHHHCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCCHHHCCHHHHCCHH
QTLYQQEAGLTYNNGPWSVLARYQHWQTLPPSIAPYSREPQLNVKYTKYNVGGFDFGAEA
HHHHHHHCCCEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCC
DYSRFRITTADATEGDRIVFNPYISYGVYGPGYFVVPKVQYHFASYDLNYLSSTTPNSPK
CCCEEEEEECCCCCCCEEEECCCEECCCCCCCEEEEEEEEEEEEEECCHHHCCCCCCCHH
RFTESIPTVTFDTGLIFDRSVRLFGQDFIQTLEPRLYYVYTPYRDQSNAPLFDTAESDFG
HHHHCCCEEEEECCEEEECHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCCC
LAEIYQPNTFVGNDRIADANRITAGLTSRFIDPRTGDERARFVIAQQYYFADQRVTLNPG
EEEEECCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCEEEECCC
QAAVLARHSDLIVGAALKLGSGFMSETAFQYNQNNNQLVKSSVGFGYSPGERRVINVGYR
CEEEEEECCCEEEEEHHHHCCCHHHHHEEEECCCCCEEEEECCCCCCCCCCCEEEEECEE
YTRANTTLDNQPINQFLVSAQWPLTRRLYAIGRFNYDLAGDRVVDGLVGLQYDADCWALG
EEECCCCCCCCCHHHHHEECCCCHHHEEEEEECCCCCCCCCHHHHHHHCCEECCCEEEEE
VGVQRAANGINSSGQQNSSTRFMMQLTLKGLSTVDNGLVSAFRAGVPGYTPLPPPPPPMS
CCHHHHHCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
RFSNYE
HCCCCC
>Mature Secondary Structure 
PPKPLFPNVFPGDGAPRKRRLALALLAVPGLVPAVSYAQLSGAAAQPQPLDSPWDLRLA
CCCCCCCCCCCCCCCCCHHHHEEEEHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEC
PQLEDHPLKDGAKPAAFVIADHTSGTAEQDLAAKGSAELRRGDAVVKADAIHYDQDTDMA
CCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCHHHCCCEEEEEEEEECCCCCCHH
DAYGQVKVINGGTSFAGPEAHLKIEANQGFMTAPKYHFNVTGGSGSAERVDMVDNERSVF
HCCCEEEEEECCCCCCCCCEEEEEECCCCEEECCEEEEEEECCCCCCCEEEEECCCCEEE
VNGTYTACQCSTNPAWYIKGSRFDFDTGADEGTARNGVLFFQGVPIFASPWMTFPLSGER
EECCEEEEEECCCCEEEEECCEECCCCCCCCCCCCCCEEEEECCCEEECCCEEECCCCCC
RSGLLPPTFSMNSSNGFELSLPYYFNIAPNRDLTLTPRIISRRGVMTEATFRYLSPSYSG
CCCCCCCCEECCCCCCEEEECCEEEEECCCCCEEECHHHHHCCCCEEHHHHHHCCCCCCC
TFTANYLPDDRLAHRNRYAIYWQHQQNFGGGFGGYVYYNKVSDNTYPEDLGSANQFINGT
EEEECCCCCHHHHCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCCHHHCCHHHHCCHH
QTLYQQEAGLTYNNGPWSVLARYQHWQTLPPSIAPYSREPQLNVKYTKYNVGGFDFGAEA
HHHHHHHCCCEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCC
DYSRFRITTADATEGDRIVFNPYISYGVYGPGYFVVPKVQYHFASYDLNYLSSTTPNSPK
CCCEEEEEECCCCCCCEEEECCCEECCCCCCCEEEEEEEEEEEEEECCHHHCCCCCCCHH
RFTESIPTVTFDTGLIFDRSVRLFGQDFIQTLEPRLYYVYTPYRDQSNAPLFDTAESDFG
HHHHCCCEEEEECCEEEECHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCCC
LAEIYQPNTFVGNDRIADANRITAGLTSRFIDPRTGDERARFVIAQQYYFADQRVTLNPG
EEEEECCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCEEEECCC
QAAVLARHSDLIVGAALKLGSGFMSETAFQYNQNNNQLVKSSVGFGYSPGERRVINVGYR
CEEEEEECCCEEEEEHHHHCCCHHHHHEEEECCCCCEEEEECCCCCCCCCCCEEEEECEE
YTRANTTLDNQPINQFLVSAQWPLTRRLYAIGRFNYDLAGDRVVDGLVGLQYDADCWALG
EEECCCCCCCCCHHHHHEECCCCHHHEEEEEECCCCCCCCCHHHHHHHCCEECCCEEEEE
VGVQRAANGINSSGQQNSSTRFMMQLTLKGLSTVDNGLVSAFRAGVPGYTPLPPPPPPMS
CCHHHHHCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
RFSNYE
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA