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The map label for this gene is ribB [H]

Identifier: 116690708

GI number: 116690708

Start: 2977691

End: 2978401

Strand: Reverse

Name: ribB [H]

Synonym: Bcen2424_2688

Alternate gene names: 116690708

Gene position: 2978401-2977691 (Counterclockwise)

Preceding gene: 116690709

Following gene: 116690702

Centisome position: 85.49

GC content: 69.9

Gene sequence:

>711_bases
ATGTCCTTGATGTCCGTTTCGTCGGCGCCTGCCGACGCCTTTGCCGATCTCCCCCTGCTGGATGCCGAACCGGTGCCGCC
GCGCATCGCCGCCGCGCTCGACGCGATGCGTGCCGGCCGCGCGGTCGTGCTGCAGGACGACCACGACCGCGAGAACGAAG
CCGATCTGATCGTCGCCGCCGAGCGCATCACGCCCGAGACGATGGCGCTGCTGATCCGCGAGTGCAGCGGCATCGTCTGC
CTGTGCCTGACCGACGACACGGTGCGCGCGCTCGAACTGCCGCCGATGGTGCAGACCAACGAAAGCCGCAATGGCACCGC
GTTCACCGTGTCGATCGAGGCGCGCGAAGGCGTGCATACCGGGGTGTCGGCCGCCGATCGCGTGACGACGATCCGCGCGG
CGATCGCCGACGGCGCGAAGCCGCACGACATCGTGCGCCCCGGCCACGTGTTTCCGTTGCGTGCGCAACCGGGCGGCGTG
CTGGCGCGCCGCGGTCATACCGAAGGCACGGTCGACCTGTCGATTCTCGCGGGCCTGAAGCCGGCCGGCGTACTGTGCGA
GCTGATGAATCCGGACGGCACGATGACGCGTGGCGACGATGTCGAGCGCTTCGCGCAACGGCACGGGCTGCCGATGCTGA
CGATTGCGGAACTCGTCGAGTTCCGCGAGGCATTGGCGGCCGCGCGCGAACGCTGCTGCGAGCCGGCCTGA

Upstream 100 bases:

>100_bases
GGGCCGCTTCGCGCTGCATGCGAAGCGGGTTGTCGTTCTGTCTGTTTGCAATGCCCTGAAACGTTTTTCGCCCTAATCGT
ATTTGCGAGGAGCGTTTCAC

Downstream 100 bases:

>100_bases
GCGAAGGAAAGGCGGGCGCGTTCGCGCGCCCGTGGCGCGGCCGGATCGATCGATCCGGCCCGAATGACGATCAGGACTGC
ACGTCGCCGAATTCGCCGCG

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSLMSVSSAPADAFADLPLLDAEPVPPRIAAALDAMRAGRAVVLQDDHDRENEADLIVAAERITPETMALLIRECSGIVC
LCLTDDTVRALELPPMVQTNESRNGTAFTVSIEAREGVHTGVSAADRVTTIRAAIADGAKPHDIVRPGHVFPLRAQPGGV
LARRGHTEGTVDLSILAGLKPAGVLCELMNPDGTMTRGDDVERFAQRHGLPMLTIAELVEFREALAAARERCCEPA

Sequences:

>Translated_236_residues
MSLMSVSSAPADAFADLPLLDAEPVPPRIAAALDAMRAGRAVVLQDDHDRENEADLIVAAERITPETMALLIRECSGIVC
LCLTDDTVRALELPPMVQTNESRNGTAFTVSIEAREGVHTGVSAADRVTTIRAAIADGAKPHDIVRPGHVFPLRAQPGGV
LARRGHTEGTVDLSILAGLKPAGVLCELMNPDGTMTRGDDVERFAQRHGLPMLTIAELVEFREALAAARERCCEPA
>Mature_235_residues
SLMSVSSAPADAFADLPLLDAEPVPPRIAAALDAMRAGRAVVLQDDHDRENEADLIVAAERITPETMALLIRECSGIVCL
CLTDDTVRALELPPMVQTNESRNGTAFTVSIEAREGVHTGVSAADRVTTIRAAIADGAKPHDIVRPGHVFPLRAQPGGVL
ARRGHTEGTVDLSILAGLKPAGVLCELMNPDGTMTRGDDVERFAQRHGLPMLTIAELVEFREALAAARERCCEPA

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=197, Percent_Identity=62.9441624365482, Blast_Score=249, Evalue=9e-68,
Organism=Saccharomyces cerevisiae, GI6320695, Length=201, Percent_Identity=42.2885572139304, Blast_Score=170, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 25130; Mature: 24999

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLMSVSSAPADAFADLPLLDAEPVPPRIAAALDAMRAGRAVVLQDDHDRENEADLIVAA
CCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEE
ERITPETMALLIRECSGIVCLCLTDDTVRALELPPMVQTNESRNGTAFTVSIEAREGVHT
CCCCHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCC
GVSAADRVTTIRAAIADGAKPHDIVRPGHVFPLRAQPGGVLARRGHTEGTVDLSILAGLK
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCEEEEEEECCCC
PAGVLCELMNPDGTMTRGDDVERFAQRHGLPMLTIAELVEFREALAAARERCCEPA
CCCEEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLMSVSSAPADAFADLPLLDAEPVPPRIAAALDAMRAGRAVVLQDDHDRENEADLIVAA
CCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEE
ERITPETMALLIRECSGIVCLCLTDDTVRALELPPMVQTNESRNGTAFTVSIEAREGVHT
CCCCHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCC
GVSAADRVTTIRAAIADGAKPHDIVRPGHVFPLRAQPGGVLARRGHTEGTVDLSILAGLK
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCEEEEEEECCCC
PAGVLCELMNPDGTMTRGDDVERFAQRHGLPMLTIAELVEFREALAAARERCCEPA
CCCEEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA