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The map label for this gene is glpR [H]

Identifier: 116690694

GI number: 116690694

Start: 2963746

End: 2964630

Strand: Direct

Name: glpR [H]

Synonym: Bcen2424_2674

Alternate gene names: 116690694

Gene position: 2963746-2964630 (Clockwise)

Preceding gene: 116690690

Following gene: 116690695

Centisome position: 85.07

GC content: 67.23

Gene sequence:

>885_bases
ATGCAATTCACGCATGAATTGCGTGCGCCGACGGCGGGCAGGCCGGCCGAACGCCGTTACCGCCCTTACAATACCCGCTC
CGTCTCACGACACGACCATCGAGCCATGACCCGAGATCCCCGCCTCACCCTCAACGCGCGTCAGCAGGAATTGCTCGAAT
GGGTGCAGCGCGACGGCTTCGTGACCGTCGACGATCTCGCCGCGCACTTCGCGGTGACCCCGCAGACGATCCGCCGCGAC
GTGAACTGGCTCGCCGACCTGAACCTGCTGCGCCGCTACCATGGCGGCGCGAGCCTGCCGACCAGCTCGGAGAACGTGTC
GTACACGGCACGCCAGCGGATGTTCCACGACGAGAAGCGGCGCATCGCGGCGCTCGCGGCGTCGCACATCCCCGACCAGG
CGTCGCTGTTCATCAACCTCGGCACAACGACCGAGGAAGTCGCGCGCGCGCTGAACCGGCATCACGGGCTGCACGTGATC
ACCAACAACCTGAACGTCGCGTCGATGATGAGCGGCTACCCCGACTGCGAGGTGCTGATCACCGGCGGCATCGTGCGACC
GTGGGACAAGGGCATCGTCGGCGAGCTCGCGATCGACTTCATCCGCCAGTTCAAGGTCGACTACGCGATCATCGGCACGT
CGGCGATCGAGGCCGACGGCACGCTGCGCGATTTCGACACGCGCGAGGTGCGCGTCGCCGAGGCGATCATGCAGCATGCG
CGCACGGTCTACCTCGTGACCGACCATTCGAAGGTCGGCCGCCCGGCGCTGGTGCGCCAGGGCCATCTGAGCCAGGTGCA
CGCGCTCTTCACCGACAAGCCGCTGCCGCCCGAAATGGCCGACACGGTGGCCGCCGCCGGCACGCAGGTGTACGTCGCGG
AATGA

Upstream 100 bases:

>100_bases
CACCTCGTCGAAAGCTGAATGAACGTGCCCGCGCGAGCGGGCAATCCGCCATTGCAGCGCGATCAGCGCCATCGCGCAAA
TTCATTTGTCACATAAATCC

Downstream 100 bases:

>100_bases
CCGTTGCGATGCTGCACCGCACCTGAAACTTCAAGTGAAATCAAGAAGTTGGCGCCGCGCGCGGACCGCTCGTGGGGTGC
GTTTCTGTCAAACGGAAAAT

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MQFTHELRAPTAGRPAERRYRPYNTRSVSRHDHRAMTRDPRLTLNARQQELLEWVQRDGFVTVDDLAAHFAVTPQTIRRD
VNWLADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHHGLHVI
TNNLNVASMMSGYPDCEVLITGGIVRPWDKGIVGELAIDFIRQFKVDYAIIGTSAIEADGTLRDFDTREVRVAEAIMQHA
RTVYLVTDHSKVGRPALVRQGHLSQVHALFTDKPLPPEMADTVAAAGTQVYVAE

Sequences:

>Translated_294_residues
MQFTHELRAPTAGRPAERRYRPYNTRSVSRHDHRAMTRDPRLTLNARQQELLEWVQRDGFVTVDDLAAHFAVTPQTIRRD
VNWLADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHHGLHVI
TNNLNVASMMSGYPDCEVLITGGIVRPWDKGIVGELAIDFIRQFKVDYAIIGTSAIEADGTLRDFDTREVRVAEAIMQHA
RTVYLVTDHSKVGRPALVRQGHLSQVHALFTDKPLPPEMADTVAAAGTQVYVAE
>Mature_294_residues
MQFTHELRAPTAGRPAERRYRPYNTRSVSRHDHRAMTRDPRLTLNARQQELLEWVQRDGFVTVDDLAAHFAVTPQTIRRD
VNWLADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHHGLHVI
TNNLNVASMMSGYPDCEVLITGGIVRPWDKGIVGELAIDFIRQFKVDYAIIGTSAIEADGTLRDFDTREVRVAEAIMQHA
RTVYLVTDHSKVGRPALVRQGHLSQVHALFTDKPLPPEMADTVAAAGTQVYVAE

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=230, Percent_Identity=47.3913043478261, Blast_Score=227, Evalue=9e-61,
Organism=Escherichia coli, GI87082344, Length=237, Percent_Identity=41.7721518987342, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1788069, Length=230, Percent_Identity=29.1304347826087, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=28.6290322580645, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790753, Length=249, Percent_Identity=26.9076305220884, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789519, Length=249, Percent_Identity=26.1044176706827, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787540, Length=233, Percent_Identity=29.6137339055794, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI226510968, Length=231, Percent_Identity=29.4372294372294, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787063, Length=240, Percent_Identity=28.75, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790635, Length=253, Percent_Identity=25.6916996047431, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 33048; Mature: 33048

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFTHELRAPTAGRPAERRYRPYNTRSVSRHDHRAMTRDPRLTLNARQQELLEWVQRDGF
CCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCCCEEECHHHHHHHHHHHHCCC
VTVDDLAAHFAVTPQTIRRDVNWLADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKR
EEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
RIAALAASHIPDQASLFINLGTTTEEVARALNRHHGLHVITNNLNVASMMSGYPDCEVLI
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCEEEE
TGGIVRPWDKGIVGELAIDFIRQFKVDYAIIGTSAIEADGTLRDFDTREVRVAEAIMQHA
ECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCEECCCCCCCCCCCHHHHHHHHHHHHC
RTVYLVTDHSKVGRPALVRQGHLSQVHALFTDKPLPPEMADTVAAAGTQVYVAE
CEEEEEECCCCCCCCHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure
MQFTHELRAPTAGRPAERRYRPYNTRSVSRHDHRAMTRDPRLTLNARQQELLEWVQRDGF
CCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCCCEEECHHHHHHHHHHHHCCC
VTVDDLAAHFAVTPQTIRRDVNWLADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKR
EEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
RIAALAASHIPDQASLFINLGTTTEEVARALNRHHGLHVITNNLNVASMMSGYPDCEVLI
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCEEEE
TGGIVRPWDKGIVGELAIDFIRQFKVDYAIIGTSAIEADGTLRDFDTREVRVAEAIMQHA
ECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCEECCCCCCCCCCCHHHHHHHHHHHHC
RTVYLVTDHSKVGRPALVRQGHLSQVHALFTDKPLPPEMADTVAAAGTQVYVAE
CEEEEEECCCCCCCCHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]