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The map label for this gene is qseC [H]

Identifier: 116690674

GI number: 116690674

Start: 2940057

End: 2941610

Strand: Direct

Name: qseC [H]

Synonym: Bcen2424_2654

Alternate gene names: 116690674

Gene position: 2940057-2941610 (Clockwise)

Preceding gene: 116690673

Following gene: 116690675

Centisome position: 84.39

GC content: 71.75

Gene sequence:

>1554_bases
ATGGCCACGCCGGCCCATTCCCCTTCCCGCCACCCGACCGGCGCGCCGTCGTCGGCTGCCGACGAGGCGCGCGACGCGCG
CTACGAGAACCCGTTCGCGCCGCCCGACGAGACCGAATCGCCCGAAACGCCGCGCCCGCGCTCGCTGTTCGGCGAAATCC
TCGACTGGATGCTCGCGCCGCTGCTGCTGCTGTGGCCGATGAGCATCGCCGTCACCTATCTCGTCGCGAAGACGATCGCG
AACAGCCCGTTCGATCGCGCGCTCGAGACCAACGCCTACGTGCTCGCGCGCCAGATCCATCCGGTCAACGGCGTCGCCGA
GCTGACGCTGCCGGAGCAGACGCGCGACTTCCTGCGCGCGGACAACATCGACAGCGTCTACTTCCAGGTGCTCGGCACGC
GCGGCGAGCTGGTCGCGGGCGAGGCCGACATGCCGCTGCCGCGTGACGAGGACCGCCCGCCGCCGGGCGTCGTCGTGTTC
CGCGACGACCTGCTGCGCGGCAACGACGTGCGCGTCGCGTATACGACCGTCGCGCTGCCGCAGACGAGCGGCGCGCAGCC
CGTGCTCGTGCAGGTCGGCGAGACGCTCGACAAGCGCAATGCGCTCGCCAACGACATCATCAAGGGCGTGATCCTGCCGC
AATTCGTGATCCTGCCGCTCGCGATCCTGCTCGTCTGGTTCGGGCTGTCGCGCGGGCTCGCGCCGCTCAACGCGCTGCAG
GCGCACATCCGCGCGCGGCGGCCCGACGACCTGTCGCCCGTCGAGGCGCAGCGCGCGCCGCCCGAGATCGAGCCGCTCGT
CACGTCGTTCAACGACCTGCTCGCGCGCCTCGAACAAAACATGGCGCTGCAGAAACGCTTCATCGCCGATGCCGCGCACC
AGATGAAGACGCCGCTCGCGGGCCTGCGCACGCAGGCCGAGTTCGCGCTGCGCCACCCGGTGCCGCCCGACGTGCAGCGC
TCGCTCGAGCAGATCGCGACGAGCTCCGAGCAGGCCGCGCGGCTCGTCACGCAACTGCTGGCGCTCGCGCGCGCCGAGAA
CCGCGCGAGCGGGCTGACGTTCGAGCCGGTCGAGATCGGTTCGCTCGCGCGGCGCACCGTGCGCGACTGGGTGCAGGCCG
CGCTCGCGAAACGCATGGACCTCGGGTACGAAGGCCCGGACGACGATGCGCCGCTCGAGGTCGACGGCAACCCGGTGATG
CTGCGCGAGATGCTCGGCAACCTGGTCGACAACGCGATCCGCTATACGCCCGAAGGCGGCCGCATCACGGTGCGCGTGCG
GGCCGAGCGCGCGGCGCGGCGCGTGCATCTCGAAGTCGAGGATACCGGCCCCGGCATCCCGGCCGGCGAGCGCGAGCGCG
TCGTCGAGCGTTTCTACCGGATCCTCGGCCGCGAAGGCGACGGCAGCGGCCTCGGGCTCGCGATCGTGCGCGAGATCGCC
ACGCAGCACGGCGGCACGCTGACGCTCGACGATCACGTCTACCAGCACGCGCCGCGCCTCGCCGGCACGCTGGTGCGCAT
CAGCCTGCCGCTCACCGATACCGCCCCGGATTAA

Upstream 100 bases:

>100_bases
ATTGCCTCGAGAAGGTCGCGCCCGCGACGCCGGCCGACACGGCGGCGCCCCAGCCCGCGGCGGCCGGCACGCCGCTGCGC
TGACGCCGGGCGGCGCCGCG

Downstream 100 bases:

>100_bases
CCCTGACGCGCGCCGCCACGGCACGGCGCCAATACGCAGAAACCGGCGCTTTACCGGACGTTCACGCCACGATCGACACG
CGAAGCGACCGATTCGACAC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MATPAHSPSRHPTGAPSSAADEARDARYENPFAPPDETESPETPRPRSLFGEILDWMLAPLLLLWPMSIAVTYLVAKTIA
NSPFDRALETNAYVLARQIHPVNGVAELTLPEQTRDFLRADNIDSVYFQVLGTRGELVAGEADMPLPRDEDRPPPGVVVF
RDDLLRGNDVRVAYTTVALPQTSGAQPVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLNALQ
AHIRARRPDDLSPVEAQRAPPEIEPLVTSFNDLLARLEQNMALQKRFIADAAHQMKTPLAGLRTQAEFALRHPVPPDVQR
SLEQIATSSEQAARLVTQLLALARAENRASGLTFEPVEIGSLARRTVRDWVQAALAKRMDLGYEGPDDDAPLEVDGNPVM
LREMLGNLVDNAIRYTPEGGRITVRVRAERAARRVHLEVEDTGPGIPAGERERVVERFYRILGREGDGSGLGLAIVREIA
TQHGGTLTLDDHVYQHAPRLAGTLVRISLPLTDTAPD

Sequences:

>Translated_517_residues
MATPAHSPSRHPTGAPSSAADEARDARYENPFAPPDETESPETPRPRSLFGEILDWMLAPLLLLWPMSIAVTYLVAKTIA
NSPFDRALETNAYVLARQIHPVNGVAELTLPEQTRDFLRADNIDSVYFQVLGTRGELVAGEADMPLPRDEDRPPPGVVVF
RDDLLRGNDVRVAYTTVALPQTSGAQPVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLNALQ
AHIRARRPDDLSPVEAQRAPPEIEPLVTSFNDLLARLEQNMALQKRFIADAAHQMKTPLAGLRTQAEFALRHPVPPDVQR
SLEQIATSSEQAARLVTQLLALARAENRASGLTFEPVEIGSLARRTVRDWVQAALAKRMDLGYEGPDDDAPLEVDGNPVM
LREMLGNLVDNAIRYTPEGGRITVRVRAERAARRVHLEVEDTGPGIPAGERERVVERFYRILGREGDGSGLGLAIVREIA
TQHGGTLTLDDHVYQHAPRLAGTLVRISLPLTDTAPD
>Mature_516_residues
ATPAHSPSRHPTGAPSSAADEARDARYENPFAPPDETESPETPRPRSLFGEILDWMLAPLLLLWPMSIAVTYLVAKTIAN
SPFDRALETNAYVLARQIHPVNGVAELTLPEQTRDFLRADNIDSVYFQVLGTRGELVAGEADMPLPRDEDRPPPGVVVFR
DDLLRGNDVRVAYTTVALPQTSGAQPVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLNALQA
HIRARRPDDLSPVEAQRAPPEIEPLVTSFNDLLARLEQNMALQKRFIADAAHQMKTPLAGLRTQAEFALRHPVPPDVQRS
LEQIATSSEQAARLVTQLLALARAENRASGLTFEPVEIGSLARRTVRDWVQAALAKRMDLGYEGPDDDAPLEVDGNPVML
REMLGNLVDNAIRYTPEGGRITVRVRAERAARRVHLEVEDTGPGIPAGERERVVERFYRILGREGDGSGLGLAIVREIAT
QHGGTLTLDDHVYQHAPRLAGTLVRISLPLTDTAPD

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=437, Percent_Identity=29.2906178489703, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1786783, Length=323, Percent_Identity=31.8885448916409, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790551, Length=288, Percent_Identity=33.6805555555556, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1790861, Length=324, Percent_Identity=30.8641975308642, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=33.0357142857143, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788393, Length=253, Percent_Identity=28.8537549407115, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788279, Length=313, Percent_Identity=25.5591054313099, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI145693157, Length=229, Percent_Identity=28.82096069869, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI48994928, Length=207, Percent_Identity=28.5024154589372, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1790346, Length=260, Percent_Identity=29.6153846153846, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789149, Length=223, Percent_Identity=27.3542600896861, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87082128, Length=258, Percent_Identity=29.8449612403101, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=28.310502283105, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787894, Length=266, Percent_Identity=28.9473684210526, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787374, Length=289, Percent_Identity=27.681660899654, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788713, Length=256, Percent_Identity=24.609375, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081816, Length=229, Percent_Identity=27.5109170305677, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=29.045643153527, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788549, Length=226, Percent_Identity=22.5663716814159, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790300, Length=251, Percent_Identity=30.6772908366534, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1789808, Length=233, Percent_Identity=27.4678111587983, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56676; Mature: 56545

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPAHSPSRHPTGAPSSAADEARDARYENPFAPPDETESPETPRPRSLFGEILDWMLAP
CCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LLLLWPMSIAVTYLVAKTIANSPFDRALETNAYVLARQIHPVNGVAELTLPEQTRDFLRA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEECCCCCCCCEEECCCHHHHHHHHH
DNIDSVYFQVLGTRGELVAGEADMPLPRDEDRPPPGVVVFRDDLLRGNDVRVAYTTVALP
CCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEEEC
QTSGAQPVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLNALQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AHIRARRPDDLSPVEAQRAPPEIEPLVTSFNDLLARLEQNMALQKRFIADAAHQMKTPLA
HHHHCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
GLRTQAEFALRHPVPPDVQRSLEQIATSSEQAARLVTQLLALARAENRASGLTFEPVEIG
HHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHH
SLARRTVRDWVQAALAKRMDLGYEGPDDDAPLEVDGNPVMLREMLGNLVDNAIRYTPEGG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHEECCCCC
RITVRVRAERAARRVHLEVEDTGPGIPAGERERVVERFYRILGREGDGSGLGLAIVREIA
EEEEEEECHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
TQHGGTLTLDDHVYQHAPRLAGTLVRISLPLTDTAPD
HHCCCEEEECHHHHHHCHHHHCEEEEEEECCCCCCCC
>Mature Secondary Structure 
ATPAHSPSRHPTGAPSSAADEARDARYENPFAPPDETESPETPRPRSLFGEILDWMLAP
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LLLLWPMSIAVTYLVAKTIANSPFDRALETNAYVLARQIHPVNGVAELTLPEQTRDFLRA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEECCCCCCCCEEECCCHHHHHHHHH
DNIDSVYFQVLGTRGELVAGEADMPLPRDEDRPPPGVVVFRDDLLRGNDVRVAYTTVALP
CCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEEEC
QTSGAQPVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLNALQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AHIRARRPDDLSPVEAQRAPPEIEPLVTSFNDLLARLEQNMALQKRFIADAAHQMKTPLA
HHHHCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
GLRTQAEFALRHPVPPDVQRSLEQIATSSEQAARLVTQLLALARAENRASGLTFEPVEIG
HHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHH
SLARRTVRDWVQAALAKRMDLGYEGPDDDAPLEVDGNPVMLREMLGNLVDNAIRYTPEGG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHEECCCCC
RITVRVRAERAARRVHLEVEDTGPGIPAGERERVVERFYRILGREGDGSGLGLAIVREIA
EEEEEEECHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
TQHGGTLTLDDHVYQHAPRLAGTLVRISLPLTDTAPD
HHCCCEEEECHHHHHHCHHHHCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]