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The map label for this gene is moaC [H]

Identifier: 116690658

GI number: 116690658

Start: 2921614

End: 2922102

Strand: Direct

Name: moaC [H]

Synonym: Bcen2424_2638

Alternate gene names: 116690658

Gene position: 2921614-2922102 (Clockwise)

Preceding gene: 116690656

Following gene: 116690659

Centisome position: 83.86

GC content: 68.92

Gene sequence:

>489_bases
ATGTCAGGACTCACCCATTTCGATGCCGCCGGCCACGCCCATATGGTCGACGTCGGCGACAAGCAGGAAACCCGGCGCAT
CGCGATCGCGCGGGGCACGATCCGGATGCTGCCGGCCACGTTCGCGCTGATCCGCGACGGCAAGGCCAAGAAAGGCGACG
TGCTCGGCGTCGCGCGCATCGCGGCGATCCAGGGCGCCAAACGCACGGCCGACCTGATTCCGCTGTGCCACCCGCTCGCG
CTCACGCGCGTGGCCGTCGAGTTCGAACTCGACGACGCGCTGCCGGGCGTGCATTGCGTCGTGCAGGTCGAGACGTTCGG
GCGGACCGGCGTCGAGATGGAAGCGCTGACGGCCGTCCAGGTCGGGCTGCTGACCGTCTACGACATGTGCAAGGCGGTCG
ATCGCGGGATGGTGATCACCGACGTGAGCGTACGGGAGAAGCGCGGCGGGAAGTCGGGGGACTGGAAGGCGGAAGACGCG
GCGGGGTGA

Upstream 100 bases:

>100_bases
TTGGATCGGTTCGTCGCGCCGGTACGGGATGCGGTGCCCGGCCGGTCGCGCGGCAGGATCGAGGGACGTGCGCGCGCACT
CCGTTCCACTAGAGGAAGAC

Downstream 100 bases:

>100_bases
ATACCCGGGCACCACCGGCCCGCCAATTCGAGATAAAACCGTTTTATCTCATACAATTACCGGATTCCGCACGAGAGAGC
GTGCGAACCAGCACAACAAA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MSGLTHFDAAGHAHMVDVGDKQETRRIAIARGTIRMLPATFALIRDGKAKKGDVLGVARIAAIQGAKRTADLIPLCHPLA
LTRVAVEFELDDALPGVHCVVQVETFGRTGVEMEALTAVQVGLLTVYDMCKAVDRGMVITDVSVREKRGGKSGDWKAEDA
AG

Sequences:

>Translated_162_residues
MSGLTHFDAAGHAHMVDVGDKQETRRIAIARGTIRMLPATFALIRDGKAKKGDVLGVARIAAIQGAKRTADLIPLCHPLA
LTRVAVEFELDDALPGVHCVVQVETFGRTGVEMEALTAVQVGLLTVYDMCKAVDRGMVITDVSVREKRGGKSGDWKAEDA
AG
>Mature_161_residues
SGLTHFDAAGHAHMVDVGDKQETRRIAIARGTIRMLPATFALIRDGKAKKGDVLGVARIAAIQGAKRTADLIPLCHPLAL
TRVAVEFELDDALPGVHCVVQVETFGRTGVEMEALTAVQVGLLTVYDMCKAVDRGMVITDVSVREKRGGKSGDWKAEDAA
G

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=162, Percent_Identity=55.5555555555556, Blast_Score=161, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=48.993288590604, Blast_Score=142, Evalue=6e-35,
Organism=Drosophila melanogaster, GI28574490, Length=161, Percent_Identity=50.3105590062112, Blast_Score=139, Evalue=6e-34,
Organism=Drosophila melanogaster, GI28574492, Length=145, Percent_Identity=51.0344827586207, Blast_Score=128, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17264; Mature: 17133

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLTHFDAAGHAHMVDVGDKQETRRIAIARGTIRMLPATFALIRDGKAKKGDVLGVARI
CCCCCCCCCCCCEEEEECCCCCCHHEEEEECCCCHHHHHHHEEHCCCCCCCCCCHHHHHH
AAIQGAKRTADLIPLCHPLALTRVAVEFELDDALPGVHCVVQVETFGRTGVEMEALTAVQ
HHHCCCCCCHHHHHHHHHHHHEEEEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHH
VGLLTVYDMCKAVDRGMVITDVSVREKRGGKSGDWKAEDAAG
HHHHHHHHHHHHHHCCEEEEECCHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SGLTHFDAAGHAHMVDVGDKQETRRIAIARGTIRMLPATFALIRDGKAKKGDVLGVARI
CCCCCCCCCCCEEEEECCCCCCHHEEEEECCCCHHHHHHHEEHCCCCCCCCCCHHHHHH
AAIQGAKRTADLIPLCHPLALTRVAVEFELDDALPGVHCVVQVETFGRTGVEMEALTAVQ
HHHCCCCCCHHHHHHHHHHHHEEEEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHH
VGLLTVYDMCKAVDRGMVITDVSVREKRGGKSGDWKAEDAAG
HHHHHHHHHHHHHHCCEEEEECCHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA